{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,4]],"date-time":"2026-03-04T08:07:41Z","timestamp":1772611661435,"version":"3.50.1"},"reference-count":30,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2024,8,23]],"date-time":"2024-08-23T00:00:00Z","timestamp":1724371200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,2,21]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n               <jats:sec>\n                  <jats:title>Objectives<\/jats:title>\n                  <jats:p>To evaluate the prevalence of ultrasound (US)-detected knee synovitis in patients with rheumatoid arthritis (RA) with a history of total knee arthroplasty (TKA) and to explore its association with RA disease activity and clinical outcomes.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>The present, retrospective, cross-sectional study retrieved the data from electronic medical records of patients with RA who were followed up for TKA and had musculoskeletal ultrasound assessment at the study centre from 1 January 2021 through 31 December 2021.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Forty-two patients with 67 post-TKA knee joints were enrolled in the present study. US-detected synovitis of the post-TKA knee was present in 15 knees (22.4%) and 12 patients (28.6%). There was no difference in disease activity scores or the pain domain of Knee Injury and Osteoarthritis Outcome Score between the patients with (n\u2009=\u200912) and without (n\u2009=\u200930) US-detected knee synovitis. The proportion of patients with the intensification of antirheumatic drugs after MSUS assessment was significantly higher in patients with US-detected synovitis compared to those without US-detected synovitis (41.7 versus 6.7%, P\u2009=\u2009.01).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>US-detected synovitis of the knee was present at 22.4% of post-TKA knee joints. Patients with US-detected synovitis of post-TKA knees were likely to receive an intensification of antirheumatic drugs.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/mr\/roae074","type":"journal-article","created":{"date-parts":[[2024,8,23]],"date-time":"2024-08-23T23:33:22Z","timestamp":1724456002000},"page":"280-286","source":"Crossref","is-referenced-by-count":2,"title":["Ultrasound-detected knee synovitis in patients with rheumatoid arthritis after total knee arthroplasty"],"prefix":"10.1093","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8724-6393","authenticated-orcid":false,"given":"Yuji","family":"Miyoshi","sequence":"first","affiliation":[{"name":"The Department of Rheumatic Diseases, Tokyo Metropolitan Tama Medical Center , Fuchu, Tokyo,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eisuke","family":"Takamasu","sequence":"additional","affiliation":[{"name":"The Department of Rheumatic Diseases, Tokyo Metropolitan Tama Medical Center , Fuchu, Tokyo,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryosuke","family":"Takada","sequence":"additional","affiliation":[{"name":"The Department of Rheumatic Diseases, Tokyo Metropolitan Tama Medical Center , Fuchu, Tokyo,","place":["Japan"]},{"name":"The Department of Rheumatic Surgery, Tokyo Metropolitan Tama Medical Center , Fuchu, Tokyo,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuichi","family":"Nagase","sequence":"additional","affiliation":[{"name":"The Department of Rheumatic Diseases, Tokyo Metropolitan Tama Medical Center , Fuchu, Tokyo,","place":["Japan"]},{"name":"The Department of Rheumatic Surgery, Tokyo Metropolitan Tama Medical Center , Fuchu, 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