{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,3,5]],"date-time":"2025-03-05T05:48:18Z","timestamp":1741153698098,"version":"3.38.0"},"reference-count":39,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2024,8,22]],"date-time":"2024-08-22T00:00:00Z","timestamp":1724284800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,2,21]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n               <jats:sec>\n                  <jats:title>Objective<\/jats:title>\n                  <jats:p>Rheumatoid pleural effusion (RPE) usually occurs in middle-aged men. Pleural fluid analyses have revealed high lactate dehydrogenase (LDH) levels and low pH and glucose levels in RPE. We aimed to investigate the clinical and laboratory features of patients with RPE since the beginning of the 21st century.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Medical records of patients with RPE were reviewed between May 2006 and October 2021. The patients were divided into &amp;lt;60\u2009year (younger) and \u226560\u2009year (older) groups.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>The younger group comprised 6 patients (median age 53.5\u2009years, female 33%) and older group comprised 23 patients (median age 76\u2009years, female 52.2%). Compared to the younger group, the older group had fewer cases of fever (83.3 versus 18.2%, P\u2009=\u2009.007) and chest pain (66.7 versus 8.7%, P\u2009=\u2009.008). In pleural fluid analysis, the older group presented higher pH (P\u2009=\u2009.004) and lower LDH levels (P\u2009=\u2009.044). Seven patients died during the follow-up period.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>Most patients with RPE were over 60\u2009years of age, and approximately half of them were female. The pleural fluid analysis showed milder inflammation in older patients than in middle-aged patients. The mortality rate of patients with RPE was distinctly higher than that previously reported.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/mr\/roae082","type":"journal-article","created":{"date-parts":[[2024,8,22]],"date-time":"2024-08-22T23:32:20Z","timestamp":1724369540000},"page":"249-255","source":"Crossref","is-referenced-by-count":0,"title":["New perspective on the clinical and laboratory characteristics of rheumatoid pleural effusion: A 29-case series"],"prefix":"10.1093","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-7184-2242","authenticated-orcid":false,"given":"Saki Sada","family":"Minoda","sequence":"first","affiliation":[{"name":"Department of General Internal Medicine, Tenri Hospital , Nara,","place":["Japan"]},{"name":"Department of Respiratory Medicine and Clinical Immunology, Graduate School of Medicine, Osaka University , Osaka,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1455-6822","authenticated-orcid":false,"given":"Ryuichi Minoda","family":"Sada","sequence":"additional","affiliation":[{"name":"Department of General Internal Medicine, Tenri Hospital , Nara,","place":["Japan"]},{"name":"Department of Transformative Protection to Infectious Disease, Graduate School of Medicine, Osaka University , Osaka,","place":["Japan"]},{"name":"Department of Infection Control, Graduate School of Medicine, Osaka University , Osaka,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroyuki","family":"Akebo","sequence":"additional","affiliation":[{"name":"Department of General Internal Medicine, Tenri Hospital , Nara,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yukio","family":"Tsugihashi","sequence":"additional","affiliation":[{"name":"Medical Home Care Centre, Tenri Hospital Shirakawa Branch , Nara,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuhiro","family":"Hatta","sequence":"additional","affiliation":[{"name":"Department of General Internal Medicine, Tenri Hospital , Nara,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2024,8,22]]},"reference":[{"key":"2025030423304536600_R1","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1007\/s00296-020-04731-0","article-title":"The global prevalence of rheumatoid arthritis: a meta-analysis based on a systematic review","volume":"41","author":"Almutairi","year":"2021","journal-title":"Rheumatol Int"},{"key":"2025030423304536600_R2","doi-asserted-by":"crossref","first-page":"722","DOI":"10.1136\/ard.62.8.722","article-title":"Extra-articular disease manifestations in rheumatoid arthritis: incidence trends and risk factors over 46 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