{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T02:09:40Z","timestamp":1777860580818,"version":"3.51.4"},"reference-count":40,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2025,3,10]],"date-time":"2025-03-10T00:00:00Z","timestamp":1741564800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,10,28]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Enthesitis has been reported in Beh\u00e7et\u2019s disease (BD); however, the analysis remains insufficient. This study examined the clinical characteristics of patients with BD presenting with enthesitis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A single-centre, observational, retrospective cohort study was conducted by reviewing medical records. Cases of BD with enthesitis were registered, and BD cases without enthesitis served as a control group. Statistical analysis included the Mann\u2013Whitney U test, Fisher\u2019s exact tests, and logistic regression analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 31 cases of BD with concomitant enthesitis were identified. The Achilles tendon was the most commonly affected site (n\u2009=\u200926, 83.9%), and arthritis frequently co-occurred (93.5% vs 66.7%, P\u2009=\u2009.002). Multivariate analysis comparing BD cases without enthesitis (n\u2009=\u200993) revealed associations of enthesitis with arthritis, pustular skin lesions, and epididymitis (P\u2009=\u2009.031, P\u2009=\u2009.036, and P\u2009=\u2009.043, respectively). The treatment response for enthesitis in BD was favourable.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Enthesitis in BD was associated with arthritis, pustular skin lesions, and epididymitis, aligning with the previously reported cluster involving pustular skin lesions, arthritis, and enthesitis. Management of BD should incorporate enthesitis considerations, and further research is essential to refine diagnostic and treatment strategies.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/mr\/roaf021","type":"journal-article","created":{"date-parts":[[2025,3,7]],"date-time":"2025-03-07T23:19:58Z","timestamp":1741389598000},"page":"1030-1034","source":"Crossref","is-referenced-by-count":2,"title":["Enthesitis in patients with Beh\u00e7et\u2019s disease: A single-centre retrospective cohort study in Japan"],"prefix":"10.1093","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4926-3528","authenticated-orcid":false,"given":"Hiroko","family":"Nagafuchi","sequence":"first","affiliation":[{"name":"Department of Rheumatology and Allergology, St. Marianna University School of Medicine , Kawasaki,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1802-5092","authenticated-orcid":false,"given":"Takayasu","family":"Ando","sequence":"additional","affiliation":[{"name":"Department of Rheumatology and Allergology, St. Marianna University School of Medicine , Kawasaki,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Machiko","family":"Mizushima","sequence":"additional","affiliation":[{"name":"Department of Rheumatology and Allergology, St. Marianna University School of Medicine , Kawasaki,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5635-345X","authenticated-orcid":false,"given":"Seido","family":"Ooka","sequence":"additional","affiliation":[{"name":"Department of Rheumatology and Allergology, St. Marianna University School of Medicine , Kawasaki,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4359-9987","authenticated-orcid":false,"given":"Kimito","family":"Kawahata","sequence":"additional","affiliation":[{"name":"Department of Rheumatology and Allergology, St. Marianna University School of Medicine , Kawasaki,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2025,3,10]]},"reference":[{"key":"2026021908112470100_R1","doi-asserted-by":"crossref","first-page":"1284","DOI":"10.1056\/NEJM199910213411707","article-title":"Beh\u00e7et\u2019s disease","volume":"341","author":"Sakane","year":"1999","journal-title":"N Engl J Med"},{"key":"2026021908112470100_R2","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1016\/j.rdc.2023.03.010","article-title":"Beh\u00e7et syndrome","volume":"49","author":"Hatemi","year":"2023","journal-title":"Rheum Dis Clin North 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