{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T14:51:26Z","timestamp":1791039086399,"version":"4.1.0"},"reference-count":30,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T00:00:00Z","timestamp":1756425600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,3,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Juvenile psoriatic arthritis (JPsA), a subtype of juvenile idiopathic arthritis, is a chronic inflammatory disease characterized by joint and skin involvement. Microvascular alterations, including endothelial dysfunction and inflammation, are thought to contribute to its pathophysiology. Nailfold videocapillaroscopy (NVC) is a noninvasive technique for assessing microvascular changes. This study aimed to evaluate NVC findings in children with JPsA compared to healthy controls, investigating the potential diagnostic and monitoring utility of NVC.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This cross-sectional study included 25 children with JPsA and 33 age- and sex-matched healthy controls. NVC was performed on eight fingers per participant, focusing on capillary density, morphology, and the presence of microhaemorrhages. Disease activity was assessed using the Juvenile Arthritis Disease Activity Score-27. Statistical analyses compared capillaroscopic findings between groups and explored correlations with clinical parameters.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>In JPsA patients, tortuous capillaries (84% vs 24%, P\u2009&amp;lt;\u2009.001), crossed capillaries (100% vs 63.6%, P\u2009=\u2009.001), and microhaemorrhages (28% vs 0%, P\u2009=\u2009.002) were significantly more frequent compared to controls. No specific capillaroscopy pattern was detected in the JPsA cohort. The capillary density and apical loop widths did not differ significantly between groups (P\u2009=\u2009.92 and P\u2009=\u2009.93, respectively). Disease duration negatively correlated with capillary density (r\u2009=\u2009\u22120.484, P\u2009=\u2009.014), suggesting progressive microvascular changes over time.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Nailfold videocapillaroscopy revealed distinct microvascular abnormalities in children with JPsA, including increased tortuosity and microhaemorrhages, highlighting its potential as a diagnostic and monitoring tool. Longitudinal studies with larger cohorts are warranted to validate these findings and clarify the prognostic significance of NVC in JPsA.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/mr\/roaf079","type":"journal-article","created":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T11:39:43Z","timestamp":1756467583000},"page":"290-298","source":"Crossref","is-referenced-by-count":1,"title":["Exploring nailfold videocapillaroscopy in children with psoriatic arthritis: are there any hidden vascular signatures?"],"prefix":"10.1093","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2774-9591","authenticated-orcid":false,"given":"Bengisu","family":"Menento\u011flu","sequence":"first","affiliation":[{"name":"Division of Pediatric Rheumatology, Department of Pediatrics, Istanbul University Faculty of Medicine, Istanbul University , Istanbul ,","place":["T\u00fcrkiye"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9950-2489","authenticated-orcid":false,"given":"Fatma G\u00fcl","family":"Demirkan","sequence":"additional","affiliation":[{"name":"Division of Pediatric Rheumatology , Department of Pediatrics, Kanuni Sultan S\u00fcleyman Training and Research Hospital, Istanbul, T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Selen Duygu","family":"Ar\u0131k","sequence":"additional","affiliation":[{"name":"Division of Pediatric Rheumatology, Department of Pediatrics, Istanbul University Faculty of Medicine, Istanbul University , Istanbul ,","place":["T\u00fcrkiye"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G\u00fcl\u015fah Kavrul","family":"Kayaalp","sequence":"additional","affiliation":[{"name":"Division of Pediatric Rheumatology, Department of Pediatrics, Istanbul University Faculty of Medicine, Istanbul University , Istanbul 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,","place":["T\u00fcrkiye"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3594-7387","authenticated-orcid":false,"given":"Nuray Aktay","family":"Ayaz","sequence":"additional","affiliation":[{"name":"Division of Pediatric Rheumatology, Department of Pediatrics, Istanbul University Faculty of Medicine, Istanbul University , Istanbul ,","place":["T\u00fcrkiye"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2025,8,29]]},"reference":[{"key":"2026030508165746500_ref1","doi-asserted-by":"crossref","first-page":"884727","DOI":"10.3389\/fped.2022.884727","article-title":"New insights on juvenile psoriatic arthritis","volume":"10","author":"Brunello","year":"2022","journal-title":"Front Pediatr"},{"key":"2026030508165746500_ref2","doi-asserted-by":"crossref","first-page":"1601","DOI":"10.3906\/sag-2011-235","article-title":"Autoimmunity in psoriatic arthritis: pathophysiological and 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