{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,6]],"date-time":"2026-07-06T10:14:42Z","timestamp":1783332882595,"version":"3.54.6"},"reference-count":30,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2025,12,10]],"date-time":"2025-12-10T00:00:00Z","timestamp":1765324800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,6,30]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>High tibial osteotomy (HTO) has traditionally been contraindicated in patients with rheumatoid arthritis (RA) owing to concerns about progressive synovitis and poor bone quality. However, advances in pharmacological treatments have challenged this concept. We aimed to evaluate the mid- to long-term outcomes of HTO in patients with well-controlled RA disease activity.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We retrospectively reviewed 13 knees in 11 patients with RA who underwent HTO between 2012 and 2022. Nine knees from seven patients with follow-up &amp;gt;\u20096\u00a0years were analyzed. Radiographic parameters included weight-bearing line percentage and medial proximal tibial angle. Bone union and clinical outcomes were assessed using the Japanese Orthopaedic Association score. Disease activity was monitored using Disease Activity Score 28. Conversion to total knee arthroplasty (TKA) was recorded.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>At final follow-up (mean, 8.3\u00a0years), all patients maintained low disease activity or remission. Weight-bearing line percentage and medial proximal tibial angle significantly increased postoperatively. The mean Japanese Orthopaedic Association score increased from 63.3 to 86.7 (P\u2009&amp;lt;\u2009.001). Bone union was achieved within 18\u00a0months in all cases, and no patient required conversion to TKA.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>HTO is a viable joint-preserving option for patients with RA and controlled disease activity, providing favourable long-term outcomes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/mr\/roaf119","type":"journal-article","created":{"date-parts":[[2025,12,8]],"date-time":"2025-12-08T12:38:33Z","timestamp":1765197513000},"page":"550-557","source":"Crossref","is-referenced-by-count":0,"title":["Mid- to long-term outcomes of high tibial osteotomy in patients with rheumatoid arthritis"],"prefix":"10.1093","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-7088-5371","authenticated-orcid":false,"given":"Kazunari","family":"Kuroda","sequence":"first","affiliation":[{"name":"Department of Orthopaedic Surgery, Yawata Medical Center , Komatsu, Ishikawa ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryuichi","family":"Nakamura","sequence":"additional","affiliation":[{"name":"Joint Preservation and Sports Orthopaedic Center, Harue Hospital , Fukui ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshiyuki","family":"Okamoto","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Yawata Medical Center , Komatsu, Ishikawa ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenji","family":"Fujita","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Ishikawa Prefectural Central Hospital , Kanazawa, Ishikawa ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masaki","family":"Takahashi","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Yawata Medical Center , Komatsu, Ishikawa ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryosuke","family":"Asa","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Yawata Medical Center , Komatsu, Ishikawa ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasuo","family":"Katsuki","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Yawata Medical Center , Komatsu, Ishikawa ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2025,12,10]]},"reference":[{"key":"2026070605221718000_ref1","doi-asserted-by":"publisher","first-page":"B55","DOI":"10.1016\/j.injury.2003.09.025","article-title":"TomoFix: a new LCP-concept for open wedge osteotomy of the medial proximal tibia\u2014early results in 92 cases","volume":"34","author":"Staubli","year":"2003","journal-title":"Injury"},{"key":"2026070605221718000_ref2","doi-asserted-by":"publisher","first-page":"167","DOI":"10.1007\/s00264-009-0902-2","article-title":"Evolution of open-wedge high-tibial osteotomy: experience with a special angular stable device for internal fixation without interposition material","volume":"34","author":"Staubli","year":"2010","journal-title":"Int Orthop"},{"key":"2026070605221718000_ref3","doi-asserted-by":"publisher","first-page":"e431","DOI":"10.1016\/j.eats.2014.04.004","article-title":"A novel closed-wedge high tibial osteotomy procedure to treat osteoarthritis of the knee: hybrid technique and rehabilitation measures","volume":"3","author":"Takeuchi","year":"2014","journal-title":"Arthrosc Tech"},{"key":"2026070605221718000_ref4","doi-asserted-by":"publisher","first-page":"e247","DOI":"10.1016\/j.eats.2022.10.014","article-title":"Flexion contracture in knee osteoarthritis can be fully eliminated by hybrid closed wedge high tibial osteotomy using a reduction-insertion-compression handle","volume":"12","author":"Nakamura","year":"2023","journal-title":"Arthrosc Tech"},{"key":"2026070605221718000_ref5","doi-asserted-by":"publisher","first-page":"e2169","DOI":"10.1016\/j.eats.2022.08.018","article-title":"Ankle-angle-adjusting fibular osteotomy in closed wedge high tibial osteotomy","volume":"11","author":"Nakamura","year":"2022","journal-title":"Arthrosc Tech"},{"key":"2026070605221718000_ref6","first-page":"95","article-title":"High tibial osteotomy for arthritis of the knee. 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