{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T23:16:41Z","timestamp":1740179801267,"version":"3.37.3"},"reference-count":13,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2021,11,18]],"date-time":"2021-11-18T00:00:00Z","timestamp":1637193600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,6,24]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n               <jats:p>Dermatomyositis is associated with malignancies and is known to have systemic involvement. However, associations with bone diseases have not been well described in the current literature. This article describes the second reported case of the co-existence of dermatomyositis and Paget\u2019s disease of bone (PDB), but this is the first report to describe such co-existence in a specific subtype of dermatomyositis\u2014hypomyopathic dermatomyositis. Our patient was a 51\u2009year old woman who presented with prolonged fever, myalgia, morning stiffness, and rashes pathognomonic of dermatomyositis. There was no muscle weakness clinically, although muscle enzymes were increased and electromyogram revealed myopathic changes. Further imaging showed the incidental finding of a T11 vertebral bone lesion, of which biopsy confirmed the diagnosis of PDB. Our report illustrates the diagnostic approach to bone lesions in patients with dermatomyositis and takes a closer look at the pathophysiology and management implications of the co-occurrence of these two rare diseases.<\/jats:p>","DOI":"10.1093\/mrcr\/rxab050","type":"journal-article","created":{"date-parts":[[2021,11,18]],"date-time":"2021-11-18T11:16:08Z","timestamp":1637234168000},"page":"291-295","source":"Crossref","is-referenced-by-count":1,"title":["A case of Paget\u2019s disease of bone associated with hypomyopathic dermatomyositis"],"prefix":"10.1093","volume":"6","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4587-6060","authenticated-orcid":false,"given":"Karina Ruth","family":"Soenjoyo","sequence":"first","affiliation":[{"name":"Department of General Medicine, Sengkang General Hospital , Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marvin Wei Jie","family":"Chua","sequence":"additional","affiliation":[{"name":"Department of General Medicine, Sengkang General Hospital , Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2021,11,18]]},"reference":[{"key":"2022062410204952700_R1","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1007\/s40257-020-00502-6","article-title":"Dermatomyositis: an update on diagnosis and treatment","volume":"21","author":"Cobos","year":"2020","journal-title":"AM J Chin Dermatol"},{"key":"2022062410204952700_R2","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1056\/NEJM199202063260602","article-title":"Risk of cancer in patients with dermatomyositis or polymyositis. A population-based study","volume":"326","author":"Sigurgeirsson","year":"1992","journal-title":"N Engl J Med"},{"key":"2022062410204952700_R3","doi-asserted-by":"crossref","first-page":"1298","DOI":"10.1016\/j.amjmed.2018.04.028","article-title":"Paget\u2019s disease of bone: diagnosis and treatment","volume":"131","author":"Kravets","year":"2018","journal-title":"Am J Med"},{"key":"2022062410204952700_R4","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/0738-081X(88)90044-2","article-title":"History and classification of polymyositis and dermatomyositis","volume":"6","author":"Bohan","year":"1988","journal-title":"Clin Dermatol"},{"key":"2022062410204952700_R5","first-page":"289","article-title":"A case series of Paget\u2019s disease of bone: diagnosing a rather uncommon condition in Singapore","volume":"27","author":"Hsu","year":"1998","journal-title":"Ann Acad Med"},{"key":"2022062410204952700_R6","doi-asserted-by":"crossref","first-page":"4408","DOI":"10.1210\/jc.2014-2910","article-title":"Paget\u2019s disease of bone: an endocrine society clinical practice guideline","volume":"99","author":"Singer","year":"2014","journal-title":"J Clin Endocrinol Metab"},{"key":"2022062410204952700_R7","doi-asserted-by":"crossref","first-page":"1875","DOI":"10.1007\/s00198-015-3095-0","article-title":"Bone turnover markers in Paget\u2019s disease of the bone: a systematic review and meta-analysis","volume":"26","author":"Al Nofal","year":"2015","journal-title":"Osteoporos Int"},{"key":"2022062410204952700_R8","first-page":"173","article-title":"Paget\u2019s disease of bone: review with emphasis on radiologic features, part II","volume":"24","author":"Mirra","year":"1995","journal-title":"Skeletal Radiol"},{"key":"2022062410204952700_R9","first-page":"1565","article-title":"Coexistence of Paget\u2019s disease and dermatomyositis","volume":"15","author":"Leonard-Segal","year":"1988","journal-title":"J Rheumatol"},{"key":"2022062410204952700_R10","article-title":"Study on the differentially expressed genes and signaling pathways in dermatomyositis using integrated bioinformatics method","volume":"9999","author":"Liu","year":"2020","journal-title":"Medicine (Baltimore)"},{"key":"2022062410204952700_R11","doi-asserted-by":"crossref","first-page":"1365","DOI":"10.1002\/art.1780291109","article-title":"Prevalence of Coxsackie B virus antibodies in patients with juvenile dermatomyositis","volume":"29","author":"Christensen","year":"1986","journal-title":"Arthritis Rheum"},{"key":"2022062410204952700_R12","doi-asserted-by":"crossref","first-page":"1256","DOI":"10.1002\/1097-0142(19810901)48:5<1256::AID-CNCR2820480534>3.0.CO;2-4","article-title":"Osteosarcoma arising in heterotopic ossification of dermatomyositis: case report and review of the literature","volume":"48","author":"Eckardt","year":"1981","journal-title":"Cancer"},{"key":"2022062410204952700_R13","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1007\/s002560050320","article-title":"Lymphoma arising in Paget\u2032s disease","volume":"26","author":"Yu","year":"1997","journal-title":"Skeletal Radiol"}],"container-title":["Modern Rheumatology Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/mrcr\/advance-article-pdf\/doi\/10.1093\/mrcr\/rxab050\/41818985\/rxab050.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/mrcr\/article-pdf\/6\/2\/291\/44245154\/rxab050.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/mrcr\/article-pdf\/6\/2\/291\/44245154\/rxab050.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,6,24]],"date-time":"2022-06-24T10:21:26Z","timestamp":1656066086000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/mrcr\/article\/6\/2\/291\/6430792"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11,18]]},"references-count":13,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2021,11,18]]},"published-print":{"date-parts":[[2022,6,24]]}},"URL":"https:\/\/doi.org\/10.1093\/mrcr\/rxab050","relation":{},"ISSN":["2472-5625"],"issn-type":[{"type":"electronic","value":"2472-5625"}],"subject":[],"published-other":{"date-parts":[[2022,6,1]]},"published":{"date-parts":[[2021,11,18]]}}}