{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T21:06:32Z","timestamp":1709327192824},"reference-count":27,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2022,11,23]],"date-time":"2022-11-23T00:00:00Z","timestamp":1669161600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,6,19]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n               <jats:p>A 24-year-old female with pneumonia two months prior presented with fever, cough, and worsening dyspnoea in the midst of a COVID-19 spike. Her initial episode was treated as COVID-19 pneumonia. On presentation, her chest computed tomography was suggestive of bilateral lower zone organising pneumonia with mild fibrosis and was attributed to post-COVID sequelae with an infective exacerbation. Oral steroids and antibiotics were administered, following which she had initial improvement and then subsequent deterioration requiring intensive care unit (ICU) care. A detailed clinical examination (in-person and virtually) at this point revealed the presence of pigmented rashes over the knuckles and weakness of hip muscles. Laboratory work showed elevated creatine kinase levels and positive anti-Ro and anti-Jo1 antibodies, which pointed to a diagnosis of antisynthetase syndrome. Unique attributes of this case include younger age of presentation in an atypical ethnic group, which are possibly incited by COVID-19 infection in the peak of a COVID-19 wave. The work-up, diagnosis, and initial management of this patient were carried out through a hybrid ICU model, which functioned as a traditional ICU in the day and a tele-ICU at night with an appropriate network of subspecialists including rheumatologists consulting, thus highlighting a collaborative model in a low-resource setting capable of managing rare cases even in the midst of increasing critical care needs during the pandemic.<\/jats:p>","DOI":"10.1093\/mrcr\/rxac088","type":"journal-article","created":{"date-parts":[[2022,11,23]],"date-time":"2022-11-23T14:04:53Z","timestamp":1669212293000},"page":"394-398","source":"Crossref","is-referenced-by-count":0,"title":["A rare presentation of antisynthetase syndrome requiring intensive care in the midst of a COVID wave"],"prefix":"10.1093","volume":"7","author":[{"given":"Akhila","family":"Arya","sequence":"first","affiliation":[{"name":"Cloudphysician Healthcare Private Limited , Bengaluru, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sanu","family":"Anand","sequence":"additional","affiliation":[{"name":"Cloudphysician Healthcare Private Limited , Bengaluru, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sandesh","family":"Kumar","sequence":"additional","affiliation":[{"name":"Cloudphysician Healthcare Private Limited , Bengaluru, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carl","family":"Britto","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Boston Children\u2019s Hospital , Boston, MA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2022,11,23]]},"reference":[{"key":"2023061920011987300_R1","first-page":"130","article-title":"New insights into antisynthetase syndrome","volume":"11","author":"Cojocaru","year":"2016","journal-title":"M\u00e6dica"},{"key":"2023061920011987300_R2","article-title":"Risks of 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