{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T17:17:14Z","timestamp":1787505434874,"version":"build-2736575974"},"reference-count":18,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2022,11,24]],"date-time":"2022-11-24T00:00:00Z","timestamp":1669248000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,6,19]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>A 68-year-old male patient presented with a 2-week history of malaise and anuria. Renal replacement therapy with haemodialysis was begun for acute kidney injury. His anti-glomerular basement membrane (anti-GBM) antibody titre was 3060\u2009U\/ml. Based on this finding, anti-GBM disease was diagnosed. Plasmapheresis and high-dose glucocorticoid therapy were begun, but his haemolytic anaemia and thrombocytopenia progressed. A disintegrin and metalloprotease with thrombospondin type 1 motif, 13 (ADAMTS-13) activity decreased to 33%, but no inhibitor was detected. Secondary thrombotic microangiopathy was suspected, and rituximab therapy was begun. The addition of rituximab is thought to have further reduced the anti-GBM antibodies, prevented recurrence, stabilised the platelet count, and facilitated the patient\u2019s withdrawal from plasmapheresis and glucocorticoid therapy. Rituximab may be a viable therapeutic option for anti-GBM diseases complicated with thrombotic microangiopathy.<\/jats:p>","DOI":"10.1093\/mrcr\/rxac091","type":"journal-article","created":{"date-parts":[[2022,11,24]],"date-time":"2022-11-24T07:10:25Z","timestamp":1669273825000},"page":"422-425","source":"Crossref","is-referenced-by-count":2,"title":["Anti-glomerular basement membrane diseases and thrombotic microangiopathy treated with rituximab"],"prefix":"10.1093","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5744-6965","authenticated-orcid":false,"given":"Nanase","family":"Honda","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Hino Municipal Hospital , Tokyo, Japan"},{"name":"Department of Rheumatic Diseases, Tokyo Metropolitan Tama Medical Center , Tokyo, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rihiro","family":"Shigehara","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, 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