{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,6]],"date-time":"2026-04-06T14:54:20Z","timestamp":1775487260488,"version":"3.50.1"},"reference-count":24,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2024,1,16]],"date-time":"2024-01-16T00:00:00Z","timestamp":1705363200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,7,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n               <jats:p>Salivary gland ultrasonography is a non-invasive imaging technique that helps in the diagnosis and assessment of disease activity in Sj\u00f6gren\u2019s syndrome. However, it remains unclear whether the salivary gland ultrasonography findings are reversible in response to treatment. We present a case of a woman in her 20s who presented with parotid swelling and pain lasting for 3 months. The patient was diagnosed with anti-SS-A antibody-positive Sj\u00f6gren\u2019s syndrome with active sialadenitis, and short-term glucocorticoid treatment resulted in resolution of clinical symptoms and improvement of salivary gland ultrasonography findings by the Outcome Measures in Rheumatology Clinical Trials scoring system. Notably, the anechoic\/hypoechoic foci and vascular signals in the parotid and submandibular glands were reduced after treatment. Furthermore, peak systolic blood flow velocity of the facial artery entering the submandibular gland was decreased. Our case highlights that the findings of \u2018inflammatory\u2019 structural changes and vascularisation on salivary gland ultrasonography, including the Outcome Measures in Rheumatology Clinical Trials scoring system, reflect the disease active of Sj\u00f6gren\u2019s syndrome and are reversible with treatment. Salivary gland ultrasonography has the potential to be a useful tool for monitoring treatment response and stratifying patients by disease activity in Sj\u00f6gren\u2019s syndrome; therefore, further research is needed on the relationship of salivary gland ultrasonography findings with the pathophysiological mechanisms of sialadenitis and long-term clinical outcomes.<\/jats:p>","DOI":"10.1093\/mrcr\/rxae002","type":"journal-article","created":{"date-parts":[[2024,1,16]],"date-time":"2024-01-16T10:52:43Z","timestamp":1705402363000},"page":"286-290","source":"Crossref","is-referenced-by-count":4,"title":["Improvement of active salivary gland ultrasonography findings in Sj\u00f6gren\u2019s syndrome in response to short-term glucocorticoid treatment: A case report and review of the literature"],"prefix":"10.1093","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5740-8352","authenticated-orcid":false,"given":"Takashi","family":"Kida","sequence":"first","affiliation":[{"name":"Inflammation and Immunology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine , Kyoto, Japan"},{"name":"Nagoya Rheumatology Clinic , Nagoya, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yutaka","family":"Kawahito","sequence":"additional","affiliation":[{"name":"Inflammation and Immunology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine , Kyoto, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yusuke","family":"Suzuki","sequence":"additional","affiliation":[{"name":"Nagoya Rheumatology Clinic , Nagoya, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shigenori","family":"Tamaki","sequence":"additional","affiliation":[{"name":"Nagoya Rheumatology Clinic , Nagoya, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ikuko","family":"Tanaka","sequence":"additional","affiliation":[{"name":"Nagoya Rheumatology Clinic , Nagoya, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2024,1,16]]},"reference":[{"key":"2024070814411631200_R1","doi-asserted-by":"crossref","DOI":"10.1007\/s11926-020-00914-7","article-title":"Sonographic features of salivary glands in Sjogren\u2019s syndrome and its mimics","volume":"22","author":"James-Goulbourne","year":"2020","journal-title":"Curr Rheumatol Rep"},{"key":"2024070814411631200_R2","doi-asserted-by":"crossref","first-page":"3522","DOI":"10.1093\/rheumatology\/kez079","article-title":"Salivary gland ultrasonography in primary Sjogren\u2019s syndrome: opportunities and challenges","volume":"60","author":"Devauchelle-Pensec","year":"2021","journal-title":"Rheumatology 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