{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T23:16:59Z","timestamp":1740179819078,"version":"3.37.3"},"reference-count":13,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2024,3,2]],"date-time":"2024-03-02T00:00:00Z","timestamp":1709337600000},"content-version":"vor","delay-in-days":3,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,7,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n               <jats:p>Lupus protein-losing enteropathy (LUPLE) is a rare condition in patients with systemic lupus erythematosus (SLE). Since the causes and exact pathological mechanism have not been elucidated, appropriate treatment has not been determined. Here, we report the case of a 69-year-old woman with systemic lupus erythematosus who developed LUPLE which was successfully treated with belimumab without an increase in glucocorticoid dose. This case suggests that belimumab monotherapy may be a treatment option for LUPLE.<\/jats:p>","DOI":"10.1093\/mrcr\/rxae010","type":"journal-article","created":{"date-parts":[[2024,3,2]],"date-time":"2024-03-02T18:14:38Z","timestamp":1709403278000},"page":"264-266","source":"Crossref","is-referenced-by-count":0,"title":["Successful treatment of lupus protein-losing enteropathy with belimumab: A case report"],"prefix":"10.1093","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7637-4867","authenticated-orcid":false,"given":"Marenori","family":"Kojima","sequence":"first","affiliation":[{"name":"Division of Rheumatology, Center for Rheumatic Diseases, Seirei Yokohama Hospital , Yokohama, Kanagawa, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hironari","family":"Hanaoka","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Division of Rheumatology, Keio University School of Medicine , Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kaito","family":"Aoki","sequence":"additional","affiliation":[{"name":"Division of Rheumatology, Center for Rheumatic Diseases, Seirei Yokohama Hospital , Yokohama, Kanagawa, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiromi","family":"Matsushita","sequence":"additional","affiliation":[{"name":"Division of Rheumatology, Center for Rheumatic Diseases, Seirei Yokohama Hospital , Yokohama, Kanagawa, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroshi","family":"Ito","sequence":"additional","affiliation":[{"name":"Division of Rheumatology, Center for Rheumatic Diseases, Seirei Yokohama Hospital , Yokohama, Kanagawa, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hidehiro","family":"Yamada","sequence":"additional","affiliation":[{"name":"Division of Rheumatology, Center for Rheumatic Diseases, Seirei Yokohama Hospital , Yokohama, Kanagawa, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2024,2,28]]},"reference":[{"key":"2024082915174848600_R1","first-page":"162","article-title":"Protein-losing enteropathy in systemic lupus erythematosus","volume":"55","author":"Pachas","year":"1971","journal-title":"Am J Gastroenterol"},{"key":"2024082915174848600_R2","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1097\/MEG.0b013e32834f3ea0","article-title":"Protein-losing enteropathy associated with or without systemic autoimmune disease: what are the differences?","volume":"24","author":"Law","year":"2012","journal-title":"Eur J Gastroenterol Hepatol"},{"key":"2024082915174848600_R3","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1093\/rheumatology\/kei164","article-title":"Outcome of protein-losing gastroenteropathy in systemic lupus erythematosus treated with prednisolone and azathioprine","volume":"45","author":"Mok","year":"2006","journal-title":"Rheumatology"},{"key":"2024082915174848600_R4","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1111\/j.1346-8138.2011.01404.x","article-title":"Systemic lupus erythematosus complicated with protein-losing enteropathy: a case report and review of the published works","volume":"39","author":"Awazawa","year":"2012","journal-title":"J Dermatol"},{"key":"2024082915174848600_R5","doi-asserted-by":"crossref","first-page":"995","DOI":"10.1007\/s00296-011-1827-9","article-title":"Lupus protein-losing enteropathy (LUPLE): a systematic review","volume":"31","author":"Al-mogairen","year":"2011","journal-title":"Rheum Int"},{"key":"2024082915174848600_R6","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jtauto.2021.100106","article-title":"Gastrointestinal involvement in systemic lupus erythematosus: a systematic review","volume":"4","author":"Frittoli","year":"2021","journal-title":"J Transl 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Rheum"},{"key":"2024082915174848600_R13","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1007\/s12328-020-01186-5","article-title":"Lupus-associated protein losing enteropathy (LUPLE) complicated by a hypercoagulable state and successfully treated with belimumab","volume":"13","author":"Lewis","year":"2020","journal-title":"Clin J Gastroenterol"}],"container-title":["Modern Rheumatology Case 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