{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T05:48:40Z","timestamp":1783057720358,"version":"3.54.6"},"reference-count":43,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2024,9,21]],"date-time":"2024-09-21T00:00:00Z","timestamp":1726876800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,1,16]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n               <jats:p>Kikuchi\u2013Fujimoto Disease (KFD), also known as Kikuchi histiocytic necrotising lymphadenitis, is an extremely rare and benign condition that mostly affects young women. It is characterised by lymph node involvement with a predilection for the cervical region, commonly presenting with tender lymphadenopathy and a low-grade fever. The diagnosis requires excisional lymph node biopsy with immunohistochemical analysis. KFD is mostly self-limiting within a few weeks to months, with only some patients requiring symptomatic relief with non-steroidal anti-inflammatory drugs or corticosteroids, and a minority developing recurrent episodes of the disease. Importantly, it has been reported in association with systemic lupus erythematosus and, to a lesser extent, other immune-mediated inflammatory rheumatic diseases, such as Sj\u00f6gren\u2019s syndrome, whose clinical presentation itself may include lymphadenopathy. In this paper, we present an unusual case of a woman with primary Sj\u00f6gren syndrome (pSS) and a past medical history relevant for lymphoma, sarcoidosis, and thymoma, who later developed KFD, a particularly challenging diagnosis in this setting. We then performed a literature review of the association between KFD and pSS, gathering a total of 13 patients, and focusing epidemiological, clinical, and laboratory data.<\/jats:p>","DOI":"10.1093\/mrcr\/rxae058","type":"journal-article","created":{"date-parts":[[2024,9,21]],"date-time":"2024-09-21T08:47:51Z","timestamp":1726908471000},"page":"110-116","source":"Crossref","is-referenced-by-count":5,"title":["Kikuchi\u2013Fujimoto disease and primary Sj\u00f6gren\u2019s syndrome coexisting: A case-based literature review"],"prefix":"10.1093","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0511-3456","authenticated-orcid":false,"given":"Maria Jo\u00e3o","family":"Cad\u00f3rio","sequence":"first","affiliation":[{"name":"Rheumatology Department, Coimbra Local Health Unit , Coimbra,","place":["Portugal"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3819-0239","authenticated-orcid":false,"given":"Jo\u00e3o","family":"Oliveira","sequence":"additional","affiliation":[{"name":"Rheumatology Department, Coimbra Local Health Unit , Coimbra,","place":["Portugal"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jo\u00e3o","family":"Gama","sequence":"additional","affiliation":[{"name":"Anatomical Pathology Department, Coimbra Local Health Unit , Coimbra,","place":["Portugal"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9327-6935","authenticated-orcid":false,"given":"C\u00e1tia","family":"Duarte","sequence":"additional","affiliation":[{"name":"Rheumatology Department, Coimbra Local Health Unit , 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