{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T08:05:41Z","timestamp":1788854741539,"version":"build-2803163510"},"reference-count":23,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2024,10,29]],"date-time":"2024-10-29T00:00:00Z","timestamp":1730160000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,1,16]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n               <jats:p>Pachydermodactyly, an uncommon variant of digital fibromatosis, predominantly affects young men and results in fibrous swelling on the sides of the proximal interphalangeal joints. It is generally considered benign and asymptomatic, requiring only regular follow-up. Nevertheless, the absence of established diagnostic criteria has led to misdiagnoses, prompting the administration of unnecessary medications. In this report, we present a 14-year-old Japanese male with symptomatic pachydermodactyly (PDD), necessitating careful differentiation from juvenile idiopathic arthritis (JIA) due to the presence of morning stiffness. Despite exhibiting typical PDD features, the patient\u2019s age and symptoms suggested rheumatoid factor-negative polyarticular JIA. However, the lack of inflammatory findings precluded a JIA diagnosis. Following confirmation of the absence of uveitis and progression of bone destruction, the morning stiffness spontaneously resolved without active treatment. However, the patient underwent surgery for aesthetic reasons to alleviate the persistent swelling. Our case highlights the nuances of symptomatic PDD, with a literature review revealing similarities between symptomatic and asymptomatic cases. This challenges the suitability of asymptomatic status as a definitive diagnostic criterion. Our findings contribute to the ongoing efforts in establishing diagnostic criteria for PDD, aiming to reduce misdiagnoses and unnecessary medications in patients.<\/jats:p>","DOI":"10.1093\/mrcr\/rxae064","type":"journal-article","created":{"date-parts":[[2024,10,29]],"date-time":"2024-10-29T13:41:34Z","timestamp":1730209294000},"page":"224-227","source":"Crossref","is-referenced-by-count":2,"title":["Symptomatic pachydermodactyly: A case report"],"prefix":"10.1093","volume":"9","author":[{"given":"Ayaka","family":"Ito","sequence":"first","affiliation":[{"name":"Department of Rheumatology, National Hospital Organization Sagamihara National Hospital , Kanagawa,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hirotaka","family":"Tsuno","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, National Hospital Organization Sagamihara National Hospital , Kanagawa,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yusuke","family":"Yano","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, National Hospital Organization Sagamihara National Hospital , Kanagawa,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shinichi","family":"Nogi","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, National Hospital Organization Sagamihara National Hospital , Kanagawa,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshihiko","family":"Tabira","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, National Hospital Organization Sagamihara National Hospital , Kanagawa,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanako","family":"Ohmatsu","sequence":"additional","affiliation":[{"name":"Department of Dermatology, National Hospital Organization Sagamihara National Hospital , Kanagawa,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shogo","family":"Honda","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Pathology, National Hospital Organization Sagamihara National Hospital , Kanagawa,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ayako","family":"Horita","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Pathology, National Hospital Organization Sagamihara National Hospital , Kanagawa,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ikuo","family":"Saito","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Pathology, National Hospital Organization Sagamihara National Hospital , Kanagawa,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7686-3211","authenticated-orcid":false,"given":"Toshihiro","family":"Matsui","sequence":"additional","affiliation":[{"name":"Department of Rheumatology Research, Clinical Research Center for Allergy and Rheumatology, National Hospital Organization Sagamihara National Hospital , Kanagawa,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2024,10,29]]},"reference":[{"key":"2025011615481428900_R1","doi-asserted-by":"crossref","DOI":"10.1001\/archderm.1975.01630160114017","article-title":"Letter: pachydermodactyly: a variant of the true knuckle pad","volume":"111","author":"Verbov","year":"1975","journal-title":"Arch Dermatol"},{"key":"2025011615481428900_R2","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1007\/s11845-020-02378-1","article-title":"Pachydermodactyly: a systematic 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