{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T15:08:27Z","timestamp":1759331307967,"version":"build-2065373602"},"reference-count":12,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,7,25]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n               <jats:p>We report the case of a 39-year-old man who was admitted for evaluation of enlarged lymph nodes. A lymph node biopsy showed CD68- and 1\u03b1-hydroxylase-positive non-caseating epithelioid granuloma. Sarcoidosis was diagnosed because of mildly elevated angiotensin-converting enzyme levels and hypercalcemia. We noted tattoos (which were created 10\u00a0years earlier) on the left upper arm and forearm. It was hypothesised that some component in the tattoos had triggered a systemic foreign body reaction by macrophages, resulting in sarcoidosis. Treatment with steroids was ineffective, but additional treatment with methotrexate plus adalimumab was successful.<\/jats:p>","DOI":"10.1093\/mrcr\/rxaf036","type":"journal-article","created":{"date-parts":[[2025,7,4]],"date-time":"2025-07-04T06:03:09Z","timestamp":1751608989000},"source":"Crossref","is-referenced-by-count":0,"title":["A case of tattoo-related sarcoidosis with generalised lymph node enlargement"],"prefix":"10.1093","volume":"9","author":[{"given":"Ukyo","family":"Yamamoto","sequence":"first","affiliation":[{"name":"Nephrology Centern, Toranomon Hospital , Tokyo ,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daisuke","family":"Ikuma","sequence":"additional","affiliation":[{"name":"Nephrology Center, Toranomon Hospital , Tokyo ,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuki","family":"Oba","sequence":"additional","affiliation":[{"name":"Nephrology Center, Toranomon Hospital , Tokyo ,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroki","family":"Mizuno","sequence":"additional","affiliation":[{"name":"Nephrology Center, Toranomon Hospital , Tokyo ,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akinari","family":"Sekine","sequence":"additional","affiliation":[{"name":"Nephrology Center, Toranomon Hospital , Tokyo ,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masayuki","family":"Yamanouchi","sequence":"additional","affiliation":[{"name":"Nephrology Center, Toranomon Hospital , Tokyo ,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eiko","family":"Hasegawa","sequence":"additional","affiliation":[{"name":"Nephrology Center, Toranomon Hospital , Tokyo ,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suwa Tatsuya","family":"Suwabebe","sequence":"additional","affiliation":[{"name":"Nephrology Center, Toranomon Hospital , Tokyo ,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kei","family":"Kono","sequence":"additional","affiliation":[{"name":"Department of Pathology, Toranomon Hospital , Tokyo ,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenichi","family":"Ohashi","sequence":"additional","affiliation":[{"name":"Department of Pathology, Toranomon Hospital , Tokyo ,","place":["Japan"]},{"name":"Department of Human Pathology, Institute of Science Tokyo, \u00a0 Tokyo ,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takehiko","family":"Wada","sequence":"additional","affiliation":[{"name":"Nephrology Center, Toranomon Hospital , Tokyo ,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naoki","family":"Sawa","sequence":"additional","affiliation":[{"name":"Nephrology Center, Toranomon Hospital , Tokyo ,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshifumi","family":"Ubara","sequence":"additional","affiliation":[{"name":"Nephrology Center, Toranomon Hospital , Tokyo ,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2025,7,4]]},"reference":[{"key":"2025093008414890700_ref1","doi-asserted-by":"crossref","first-page":"242","DOI":"10.4103\/jomfp.jomfp_373_21","article-title":"Sarcoidosis - a review article","volume":"26","author":"Sreeja","year":"2022","journal-title":"J Oral Maxillofac Pathol"},{"key":"2025093008414890700_ref2","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1186\/s12931-020-01409-w","article-title":"Immunoreactivity to metal and silica associates with sarcoidosis in Dutch patients","volume":"21","author":"Beijer","year":"2020","journal-title":"Respir Res"},{"key":"2025093008414890700_ref3","doi-asserted-by":"crossref","first-page":"2321","DOI":"10.1007\/s11999-010-1372-y","article-title":"Histological features of pseudotumor-like tissues from metal-on-metal hips","volume":"468","author":"Campbell","year":"2010","journal-title":"Clin Orthop Relat Res"},{"key":"2025093008414890700_ref4","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1515\/cclm-2012-0492","article-title":"Metal release from hip prostheses: cobalt and chromium toxicity and the role of the clinical laboratory","volume":"51","author":"Campbell","year":"2013","journal-title":"Clin Chem Lab Med"},{"key":"2025093008414890700_ref5","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1530\/EOR-21-0098","article-title":"Prosthetic hip-associated cobalt toxicity: a systematic review of case series and case reports","volume":"7","author":"Crutsen","year":"2022","journal-title":"EFORT Open Rev"},{"key":"2025093008414890700_ref6","doi-asserted-by":"crossref","first-page":"249","DOI":"10.5371\/hp.2016.28.4.249","article-title":"Granulomatous lung disease: a novel complication following metallosis from hip arthroplasty","volume":"28","author":"Balbouzis","year":"2016","journal-title":"Hip Pelvis"},{"key":"2025093008414890700_ref7","doi-asserted-by":"crossref","first-page":"e34","DOI":"10.1056\/NEJMicm1215331","article-title":"Images in clinical medicine. Tattoos and sarcoidosis","volume":"370","author":"Torres","year":"2014","journal-title":"N Engl J Med"},{"key":"2025093008414890700_ref8","doi-asserted-by":"crossref","first-page":"1416","DOI":"10.1016\/j.amjmed.2020.04.027","article-title":"Tattoo-associated sarcoidosis","volume":"133","author":"Hirani","year":"2020","journal-title":"Am J Med"},{"key":"2025093008414890700_ref9","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1007\/s11882-018-0794-6","article-title":"Atypical cutaneous presentations of sarcoidosis: two case reports and review of the literature","volume":"18","author":"Leverenz","year":"2018","journal-title":"Curr Allergy Asthma Rep"},{"key":"2025093008414890700_ref10","doi-asserted-by":"crossref","first-page":"S71","DOI":"10.1016\/j.jaad.2005.12.022","article-title":"Sarcoid granuloma on black tattoo","volume":"55","author":"Morales-Callaghan","year":"2006","journal-title":"J Am Acad Dermatol"},{"key":"2025093008414890700_ref11","doi-asserted-by":"crossref","first-page":"e26","DOI":"10.1164\/rccm.202002-0251ST","article-title":"Diagnosis and detection of sarcoidosis. An official American Thoracic Society clinical practice guideline","volume":"201","author":"Crouser","year":"2020","journal-title":"Am J Respir Crit Care Med"},{"key":"2025093008414890700_ref12","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.clinimag.2022.01.006","article-title":"Can infections trigger sarcoidosis?","volume":"84","author":"Lampejo","year":"2022","journal-title":"Clin Imaging"}],"container-title":["Modern Rheumatology Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/mrcr\/advance-article-pdf\/doi\/10.1093\/mrcr\/rxaf036\/63668118\/rxaf036.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/mrcr\/article-pdf\/9\/2\/rxaf036\/63668118\/rxaf036.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/mrcr\/article-pdf\/9\/2\/rxaf036\/63668118\/rxaf036.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,30]],"date-time":"2025-09-30T12:42:11Z","timestamp":1759236131000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/mrcr\/article\/doi\/10.1093\/mrcr\/rxaf036\/8185786"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025]]},"references-count":12,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2025,7,25]]}},"URL":"https:\/\/doi.org\/10.1093\/mrcr\/rxaf036","relation":{},"ISSN":["2472-5625"],"issn-type":[{"type":"electronic","value":"2472-5625"}],"subject":[],"published-other":{"date-parts":[[2025]]},"published":{"date-parts":[[2025]]},"article-number":"rxaf036"}}