{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,14]],"date-time":"2026-04-14T10:20:41Z","timestamp":1776162041709,"version":"3.50.1"},"reference-count":32,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,1,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Systemic sclerosis (SSc) is a syndrome characterised by excessive fibrosis in multiple organs. Intestinal pseudo-obstruction is one of the major gastrointestinal manifestations of SSc, characterised by long-standing symptoms suggesting obstruction without a lesion identified despite endoscopic and\/or radiological examination. Septic pulmonary embolism is a rare type of pulmonary embolism in which emboli containing pathogens embolise into the pulmonary arteries and cause focal lung abscesses. The case of a 53-year-old man with SSc-associated intestinal pseudo-obstruction, who developed a septic pulmonary embolism, is described. Klebsiella pneumoniae was isolated from blood cultures. After 4 weeks of intravenous antibiotic therapy, follow-up computed tomography showed the complete disappearance of the pulmonary cavity lesions. This case suggests that patients with SSc-associated intestinal pseudo-obstruction are at risk of infection and highlights the importance of careful observation.<\/jats:p>","DOI":"10.1093\/mrcr\/rxag017","type":"journal-article","created":{"date-parts":[[2026,3,2]],"date-time":"2026-03-02T12:23:32Z","timestamp":1772454212000},"source":"Crossref","is-referenced-by-count":0,"title":["Septic pulmonary embolism in systemic sclerosis-associated intestinal pseudo-obstruction: A case report"],"prefix":"10.1093","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2464-1833","authenticated-orcid":false,"given":"Eri","family":"Sugawara","sequence":"first","affiliation":[{"name":"Department of Rheumatology, Tonan Hospital , Sapporo ,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haruka","family":"Iino","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, Tonan Hospital , Sapporo ,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8082-1009","authenticated-orcid":false,"given":"Keita","family":"Ninagawa","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, Tonan Hospital , Sapporo ,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2026,3,6]]},"reference":[{"key":"2026041405220574900_ref1","doi-asserted-by":"publisher","first-page":"304","DOI":"10.1016\/S0140-6736(22)01692-0","article-title":"Systemic sclerosis","volume":"401","author":"Volkmann","year":"2023","journal-title":"Lancet"},{"key":"2026041405220574900_ref2","doi-asserted-by":"publisher","first-page":"2437","DOI":"10.1002\/1529-0131(200011)43:11&lt;2437::AID-ANR10&gt;3.0.CO;2-U","article-title":"Severe organ involvement in systemic sclerosis with diffuse scleroderma","volume":"43","author":"Steen","year":"2000","journal-title":"Arthritis Rheum"},{"key":"2026041405220574900_ref3","doi-asserted-by":"publisher","first-page":"636","DOI":"10.1093\/rheumatology\/key350","article-title":"Severe gastrointestinal disease in very early systemic sclerosis is associated with early mortality","volume":"58","author":"Richard","year":"2019","journal-title":"Rheumatology (Oxford)"},{"key":"2026041405220574900_ref4","doi-asserted-by":"publisher","first-page":"166","DOI":"10.1038\/s41584-022-00900-6","article-title":"Systemic sclerosis gastrointestinal dysmotility: risk factors, pathophysiology, diagnosis and management","volume":"19","author":"McMahan","year":"2023","journal-title":"Nat Rev Rheumatol"},{"key":"2026041405220574900_ref5","doi-asserted-by":"publisher","first-page":"675","DOI":"10.1136\/gut.41.5.675","article-title":"Clinical characteristics of chronic idiopathic intestinal pseudo-obstruction in adults","volume":"41","author":"Mann","year":"1997","journal-title":"Gut"},{"key":"2026041405220574900_ref6","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1007\/s11938-005-0046-4","article-title":"Chronic intestinal pseudo-obstruction","volume":"8","author":"Panganamamula","year":"2005","journal-title":"Curr Treat Options Gastroenterol"},{"key":"2026041405220574900_ref7","doi-asserted-by":"publisher","first-page":"2049","DOI":"10.3899\/jrheum.131547","article-title":"Mortality, recurrence, and hospital course of patients with systemic sclerosis-related acute intestinal pseudo-obstruction","volume":"41","author":"Mecoli","year":"2014","journal-title":"J Rheumatol"},{"key":"2026041405220574900_ref8","doi-asserted-by":"publisher","first-page":"162","DOI":"10.1378\/chest.128.1.162","article-title":"Septic pulmonary embolism: presenting features and clinical course of 14 patients","volume":"128","author":"Cook","year":"2005","journal-title":"Chest"},{"key":"2026041405220574900_ref9","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.rmed.2013.10.012","article-title":"Clinical characteristics of septic pulmonary embolism in adults: a systematic review","volume":"108","author":"Ye","year":"2014","journal-title":"Respir Med"},{"key":"2026041405220574900_ref10","doi-asserted-by":"publisher","first-page":"405","DOI":"10.1016\/j.semarthrit.2019.05.005","article-title":"Evaluation of risk factors for pseudo-obstruction in systemic sclerosis","volume":"49","author":"Dein","year":"2019","journal-title":"Semin Arthritis Rheum"},{"key":"2026041405220574900_ref11","doi-asserted-by":"publisher","first-page":"654","DOI":"10.1093\/rheumatology\/kev393","article-title":"Intestinal pseudo-obstruction in patients with systemic sclerosis: an analysis of the nationwide inpatient sample","volume":"55","author":"Valenzuela","year":"2016","journal-title":"Rheumatology (Oxford)"},{"key":"2026041405220574900_ref12","doi-asserted-by":"crossref","first-page":"1545","DOI":"10.3899\/jrheum.121380","article-title":"The 15% rule in scleroderma: the frequency of severe organ complications in systemic sclerosis. 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