{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T23:02:04Z","timestamp":1790204524305,"version":"4.1.0"},"reference-count":26,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T00:00:00Z","timestamp":1785801600000},"content-version":"vor","delay-in-days":215,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,6,29]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Introduction: Prosthetic joint infection (PJI) represents a serious and challenging complication in a patient with rheumatoid arthritis. We report a case of PJI following revision total elbow arthroplasty with rheumatoid arthritis that was successfully managed with debridement, antibiotics, and implant retention augmented by continuous local antibiotic perfusion (CLAP). Case Presentation: A 69-year-old woman with a 39-year history of rheumatoid arthritis previously underwent revision total elbow arthroplasty for aseptic loosening. Two years following the revision surgery, she developed left elbow swelling, pain, and erythema, resulting in a diagnosis of PJI. Because the implant remained stable without evidence of loosening, an emergency debridement, antibiotics, and implant retention procedure was performed in conjunction with CLAP in attempt to salvage the prosthesis. Intraoperative cultures were positive for methicillin-susceptible Staphylococcus aureus. Following surgery, the patient received targeted systemic antibiotic therapy alongside continuous local gentamicin perfusion via the CLAP system. Local perfusion was discontinued on postoperative Day 18, and oral antibiotic suppressive therapy was continued for 3 months. At the 2-year follow-up examination, the patient showed no clinical evidence of recurrent infection and had maintained her preoperative elbow range of motion. Conclusion: The integration of CLAP with the debridement, antibiotics, and implant retention procedure represents a promising, prosthesis-preserving therapeutic strategy for managing PJI following revision total elbow arthroplasty.<\/jats:p>","DOI":"10.1093\/mrcr\/rxag077","type":"journal-article","created":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T11:24:57Z","timestamp":1785756297000},"source":"Crossref","is-referenced-by-count":1,"title":["Successful prosthesis salvage using continuous local antibiotic perfusion for prosthetic joint infection following revision total elbow arthroplasty in a patient with rheumatoid arthritis"],"prefix":"10.1093","volume":"10","author":[{"given":"Risa","family":"Arai","sequence":"first","affiliation":[{"name":"Department of Orthopaedic Surgery, Yamagata University Faculty of Medicine , Yamagata ,","place":["Japan"]},{"name":"Department of Orthopaedic Surgery, Nihonkai General Hospital , Yamagata ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3535-8419","authenticated-orcid":false,"given":"Yuya","family":"Takakubo","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Yamagata University Faculty of Medicine , Yamagata ,","place":["Japan"]},{"name":"Department of Rehabilitation, Yamagata University Hospital , Yamagata ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juji","family":"Ito","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Nihonkai General Hospital , Yamagata ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3389-5272","authenticated-orcid":false,"given":"Tomohiro","family":"Uno","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Yamagata University Faculty of Medicine , Yamagata 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