{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T01:08:21Z","timestamp":1792112901937,"version":"4.4.0"},"reference-count":62,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T00:00:00Z","timestamp":1779148800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"name":"Commission of the Improvement of Higher Education Personnel","award":["001"],"award-info":[{"award-number":["001"]}]},{"name":"Foundation for Research Support of Rio Grande do Sul"},{"DOI":"10.13039\/501100003593","name":"National Council for Scientific and Technological Development","doi-asserted-by":"publisher","award":["53\/2022"],"award-info":[{"award-number":["53\/2022"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003593","name":"National Council for Scientific and Technological Development","doi-asserted-by":"publisher","award":["408831\/2022-7"],"award-info":[{"award-number":["408831\/2022-7"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,8,27]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Diet quality can be a potential modifier of post-acute COVID-19 syndrome (PACS), yet the relationship between dietary patterns, symptom burden, and biological markers remains poorly understood. We hypothesized that a low-quality diet would positively associate with PACS symptom burden, DNA damage, inflammatory and neurotrophic markers, and with overall health quality. A total of 186 individuals were classified into three groups: control (n\u2009=\u200964), acute PACS (n\u2009=\u200966), and chronic PACS (n\u2009=\u200955). Dietary intake was assessed by a food frequency questionnaire, and diet quality was quantified via the Protective and Risk Eating Score (PRES). Blood samples were analyzed for inflammatory (tumor necrosis factor-\u03b1, transforming growth factor-\u03b2, interleukin-6, interleukin-1\u03b2) and neurotrophic (brain-derived neurotrophic factor, glial cell line-derived neurotrophic factor, S100 calcium-binding protein B) markers. DNA damage was assessed by micronuclei frequency, telomere length, and comet assay parameters. Health index (HI) was assessed by daily habits (alcohol consumption, sleeping patterns, hydration, exercise frequency, smoking habits, anthropometric parameters, and PRES). No significant differences were found among groups in ultra-processed foods or sugary products intake, PRES scores, inflammatory or neurotrophic biomarkers, DNA damage indicators, and HI. Of note, poorer diet quality was associated with higher symptom burden in PACS women, mainly in fatigue, memory, mental health, circulatory, and skin symptom domains. Few associations among diet quality, HI, and biomarkers emerged. Of note, principal component analysis shows that PACS relies on the convergence of genomic instability, systemic inflammation, and low diet quality. These findings suggest that diet may represent a modifiable factor in PACS management, warranting longitudinal and interventional studies to determine causality and therapeutic potential.<\/jats:p>","DOI":"10.1093\/mutage\/geag020","type":"journal-article","created":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T11:40:14Z","timestamp":1779190814000},"page":"271-284","source":"Crossref","is-referenced-by-count":1,"title":["Ultra-processed foods and diet quality in long COVID: associations with symptom burden, DNA damage, and inflammation"],"prefix":"10.1093","volume":"41","author":[{"given":"Raquel D S","family":"Freitas","sequence":"first","affiliation":[{"name":"Graduate Program on Health and Human Development, Laboratory of Genetic Toxicology, University LaSalle , Canoas, Rio Grande do Sul 92010-00 ,","place":["Brazil"]},{"name":"Lutheran University of Brazil (ULBRA) Postgraduate Program in Cellular and Molecular Biology Applied to Health , Canoas, Rio Grande do Sul ,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana L H","family":"Garcia","sequence":"additional","affiliation":[{"name":"Graduate Program on Health and Human Development, Laboratory of Genetic Toxicology, University LaSalle , Canoas, Rio Grande do Sul 92010-00 ,","place":["Brazil"]},{"name":"Lutheran University of Brazil (ULBRA) Postgraduate Program in Cellular and Molecular Biology Applied to Health , Canoas, Rio Grande do Sul ,","place":["Brazil"]},{"name":"CESUCA, University Center , Cachoeirinha, Rio Grande do Sul ,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruna A A","family":"Martins","sequence":"additional","affiliation":[{"name":"Graduate Program on Health and Human Development, Laboratory of Genetic Toxicology, University LaSalle , Canoas, Rio Grande do Sul 92010-00 ,","place":["Brazil"]},{"name":"Graduate Program in Genetics and Molecular Biology, Federal University of Rio Grande do Sul , Porto Alegre, Rio Grande do Sul ,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daiana","family":"Dalberto","sequence":"additional","affiliation":[{"name":"Graduate Program on Health and Human Development, Laboratory of Genetic Toxicology, University LaSalle , Canoas, Rio Grande do Sul 92010-00 ,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernanda R","family":"Da Silva","sequence":"additional","affiliation":[{"name":"Graduate Program on Health and Human Development, Laboratory of Genetic Toxicology, University LaSalle , Canoas, Rio Grande do Sul 92010-00 ,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Malu S","family":"Borges","sequence":"additional","affiliation":[{"name":"Graduate Program on Health and Human Development, Laboratory of Genetic Toxicology, University LaSalle , Canoas, Rio Grande do Sul 92010-00 ,","place":["Brazil"]},{"name":"Graduate Program in Genetics and Molecular Biology, Federal University of Rio Grande do Sul , Porto Alegre, Rio Grande do Sul ,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5896-3171","authenticated-orcid":false,"given":"Gumercindo E P","family":"Peralta","sequence":"additional","affiliation":[{"name":"Graduate Program on Health and Human Development, Laboratory of Genetic Toxicology, University LaSalle , Canoas, Rio Grande do Sul 92010-00 ,","place":["Brazil"]},{"name":"Graduate Program in Genetics and Molecular Biology, Federal University of Rio Grande do Sul , Porto Alegre, Rio Grande do Sul ,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Larissa D","family":"Bobermin","sequence":"additional","affiliation":[{"name":"Graduate Program in Biological Sciences: Biochemistry, Institute of Basic Health Sciences, Federal University of Rio Grande do Sul ,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andr\u00e9","family":"Quincozes-Santos","sequence":"additional","affiliation":[{"name":"Graduate Program in Biological Sciences: Biochemistry, Institute of Basic Health Sciences, Federal University of Rio Grande do Sul ,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juliana","family":"Da Silva","sequence":"additional","affiliation":[{"name":"Graduate Program on Health and Human Development, Laboratory of Genetic Toxicology, University LaSalle , Canoas, Rio Grande do Sul 92010-00 ,","place":["Brazil"]},{"name":"Graduate Program in Genetics and Molecular Biology, Federal University of Rio Grande do Sul , Porto Alegre, Rio Grande do Sul ,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,5,19]]},"reference":[{"key":"2026082709421145200_ref1","volume-title":"WHO Coronavirus (COVID-19) Dashboard &gt; Cases [Dashboard]","author":"World Health Organization","year":"2025"},{"key":"2026082709421145200_ref2","volume-title":"WHO Coronavirus (COVID-19) Dashboard &gt; Deaths [Dashboard]","author":"World Health Organization","year":"2025"},{"key":"2026082709421145200_ref3","doi-asserted-by":"publisher","first-page":"C1","DOI":"10.1152\/AJPCELL.00375.2021","article-title":"Long-term complications of COVID-19","volume":"322","author":"Desai","year":"2022","journal-title":"Am J Physiol Cell Physiol"},{"key":"2026082709421145200_ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.prp.2023.154497","article-title":"COVID-19, post-acute COVID-19 syndrome (PACS, \u201clong COVID\u201d) and post-COVID-19 vaccination syndrome (PCVS, \u201cpost-COVIDvac-syndrome\u201d): similarities and differences","volume":"246","author":"Scholkmann","year":"2023","journal-title":"Pathol Res Pract"},{"key":"2026082709421145200_ref5","doi-asserted-by":"publisher","first-page":"707","DOI":"10.1016\/S0140-6736(24)01136-X","article-title":"Long COVID: a clinical update","volume":"404","author":"Greenhalgh","year":"2024","journal-title":"Lancet"},{"key":"2026082709421145200_ref6","doi-asserted-by":"publisher","first-page":"3697","DOI":"10.2147\/DMSO.S484733","article-title":"The bidirectional association between metabolic syndrome and long-COVID-19","volume":"17","author":"Liu","year":"2024","journal-title":"Diabetes Metabolic Syndrome Obesity"},{"key":"2026082709421145200_ref7","doi-asserted-by":"publisher","first-page":"939","DOI":"10.1016\/j.cjco.2024.03.003","article-title":"Impact of long COVID-19 on health outcomes among adults with Preexisting cardiovascular disease and hypertension: a systematic review","volume":"6","author":"Daodu","year":"2024","journal-title":"CJC Open"},{"key":"2026082709421145200_ref8","doi-asserted-by":"publisher","DOI":"10.3390\/jcm11113094","article-title":"The long-term effect of COVID-19 disease severity on risk of diabetes incidence and the near 1-year follow-up outcomes among Postdischarge patients in Wuhan","volume":"11","author":"Zhang","year":"2022","journal-title":"J Clin Med"},{"key":"2026082709421145200_ref9","doi-asserted-by":"crossref","first-page":"e2455430","DOI":"10.1001\/jamanetworkopen.2024.55430","article-title":"Sex differences in long COVID","volume":"8","author":"Shah","year":"2025","journal-title":"JAMA Netw Open"},{"key":"2026082709421145200_ref10","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph191912422","article-title":"Effect of COVID-19 vaccines on reducing the risk of long COVID in the real world: a systematic review and meta-analysis","volume":"19","author":"Gao","year":"2022","journal-title":"Int J Environ Res Public Health"},{"key":"2026082709421145200_ref11","doi-asserted-by":"publisher","first-page":"758","DOI":"10.1038\/s41586-022-05542-y","article-title":"SARS-CoV-2 infection and persistence in the human body and brain at autopsy","volume":"612","author":"Stein","year":"2022","journal-title":"Nature"},{"key":"2026082709421145200_ref12","doi-asserted-by":"publisher","first-page":"881","DOI":"10.1016\/j.cell.2022.01.014","article-title":"Multiple early factors anticipate post-acute COVID-19 sequelae","volume":"185","author":"Su","year":"2022","journal-title":"Cell"},{"key":"2026082709421145200_ref13","doi-asserted-by":"publisher","DOI":"10.1186\/s12933-021-01359-7","article-title":"Persistent clotting protein pathology in long COVID\/post-acute sequelae of COVID-19 (PASC) is accompanied by increased levels of antiplasmin","volume":"20","author":"Pretorius","year":"2021","journal-title":"Cardiovasc Diabetol"},{"key":"2026082709421145200_ref14","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2023.1080043","article-title":"Gut and airway microbiota dysbiosis and their role in COVID-19 and long-COVID","volume":"14","author":"Ancona","year":"2023","journal-title":"Front Immunol"},{"key":"2026082709421145200_ref15","doi-asserted-by":"publisher","DOI":"10.1093\/mutage\/geae022","article-title":"Exploring the relationship between genetic instability and health outcomes in acute and chronic post-COVID syndrome","author":"Martins","year":"2024","journal-title":"Mutagenesis"},{"key":"2026082709421145200_ref16","doi-asserted-by":"publisher","DOI":"10.1016\/j.mrgentox.2025.503870","article-title":"Acute and chronic post-COVID-19 conditions: a study of genetic integrity and clinical markers","volume":"904","author":"Martins","year":"2025","journal-title":"Mutat Res Genet Toxicol Environ Mutagen"},{"key":"2026082709421145200_ref17","doi-asserted-by":"publisher","DOI":"10.3390\/microorganisms13051029","article-title":"The role of beneficial microbiota in COVID-19: insights from key bacterial genera","volume":"13","author":"Rampelotto","year":"2025","journal-title":"Microorganisms"},{"key":"2026082709421145200_ref18","doi-asserted-by":"publisher","DOI":"10.3390\/antiox10050708","article-title":"Diet-derived antioxidants and their role in inflammation, obesity and gut microbiota modulation","volume":"10","author":"Deledda","year":"2021","journal-title":"Antioxidants"},{"key":"2026082709421145200_ref19","doi-asserted-by":"publisher","DOI":"10.1016\/j.nut.2025.112800","article-title":"Impact of ultra-processed foods on human health: a comprehensive review of genomic instability and molecular mechanisms","volume":"137","author":"Freitas","year":"2025","journal-title":"Nutrition"},{"key":"2026082709421145200_ref20","doi-asserted-by":"publisher","DOI":"10.3390\/idr17020025","article-title":"Unhealthy food consumption is associated with post-acute sequelae of COVID-19 in Brazilian elderly people","volume":"17","author":"Ribeiro","year":"2025","journal-title":"Infect Dis Rep"},{"key":"2026082709421145200_ref21","doi-asserted-by":"crossref","first-page":"e623","DOI":"10.1093\/pubmed\/fdae134","article-title":"Association between food insecurity and long COVID in adults from southern Brazil: findings of the PAMPA cohort","volume":"46","author":"Schr\u00f6eder","year":"2024","journal-title":"J Public Health (Bangkok)"},{"key":"2026082709421145200_ref22","volume-title":"Nutrition for a Healthy Life \u2013 WHO Recommendations","author":"World Health Organization","year":"2025"},{"key":"2026082709421145200_ref23","doi-asserted-by":"publisher","DOI":"10.1136\/bmj-2022-070230","article-title":"Development and validation of the symptom burden questionnaire for long covid (SBQ-LC): Rasch analysis","author":"Hughes","year":"2022","journal-title":"The BMJ"},{"key":"2026082709421145200_ref24","doi-asserted-by":"publisher","DOI":"10.1016\/j.envpol.2021.117346","article-title":"Environmental exposure to mineral coal and by-products: influence on human health and genomic instability","volume":"287","author":"de Souza","year":"2021","journal-title":"Environ Pollut"},{"key":"2026082709421145200_ref25","doi-asserted-by":"publisher","DOI":"10.1016\/j.mrgentox.2024.503793","article-title":"Multiple factors influence telomere length and DNA damage in individuals environmentally exposed to a coal-burning power plant","volume":"898","author":"de Souza","year":"2024","journal-title":"Mutat Res Genet Toxicol Environ Mutagen"},{"key":"2026082709421145200_ref26","doi-asserted-by":"publisher","first-page":"275","DOI":"10.1007\/s00394-022-02982-0","article-title":"Impact of ultra-processed food intake on the risk of COVID-19: a prospective cohort study","volume":"62","author":"Zhou","year":"2023","journal-title":"Eur J Nutr"},{"key":"2026082709421145200_ref27","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2024.123295","article-title":"The impact of gut microbiome and diet on post-acute sequelae of SARS-CoV-2 infection","volume":"467","author":"Reyes","year":"2024","journal-title":"J Neurol Sci"},{"key":"2026082709421145200_ref28","doi-asserted-by":"publisher","DOI":"10.3389\/fnut.2025.1549747","article-title":"Vaccination and food consumption: association with post-acute COVID-19 syndrome in Brazilian adults (CUME study)","volume":"12","author":"Brand\u00e3o","year":"2025","journal-title":"Front Nutr"},{"key":"2026082709421145200_ref29","doi-asserted-by":"publisher","first-page":"114225","DOI":"10.1016\/j.physbeh.2023.114225","article-title":"High-fat-sugar diet is associated with impaired hippocampus-dependent memory in humans","volume":"268","author":"Atak","year":"2023","journal-title":"Physiol Behav"},{"key":"2026082709421145200_ref30","doi-asserted-by":"publisher","first-page":"1094","DOI":"10.1001\/jamainternmed.2015.1668","article-title":"Mediterranean diet and age-related cognitive decline: a randomized clinical trial","volume":"175","author":"Valls-Pedret","year":"2015","journal-title":"JAMA Intern Med"},{"key":"2026082709421145200_ref31","doi-asserted-by":"publisher","DOI":"10.3389\/fnut.2024.1458484","article-title":"Inflammatory diet, gut microbiota and sensorineural hearing loss: a cross-sectional and Mendelian randomization study","volume":"11","author":"Wang","year":"2024","journal-title":"Front Nutr"},{"key":"2026082709421145200_ref32","doi-asserted-by":"publisher","DOI":"10.3390\/ijms222413177","article-title":"The link between gut Dysbiosis caused by a high-fat diet and hearing loss","volume":"22","author":"Kociszewska","year":"2021","journal-title":"Int J Mol Sci"},{"key":"2026082709421145200_ref33","doi-asserted-by":"publisher","first-page":"E2334770","DOI":"10.1001\/jamanetworkopen.2023.34770","article-title":"Consumption of Ultraprocessed food and risk of depression","volume":"6","author":"Samuthpongtorn","year":"2023","journal-title":"JAMA Netw Open"},{"key":"2026082709421145200_ref34","doi-asserted-by":"publisher","DOI":"10.3390\/nu17111802","article-title":"A comprehensive scoping review on diet and nutrition in relation to long COVID-19 symptoms and recovery","volume":"17","author":"Bigman","year":"2025","journal-title":"Nutrients"},{"key":"2026082709421145200_ref35","doi-asserted-by":"publisher","DOI":"10.3390\/diagnostics12051162","article-title":"Serum NGF and BDNF in long-COVID-19 adolescents: a pilot study","volume":"12","author":"Petrella","year":"2022","journal-title":"Diagnostics"},{"key":"2026082709421145200_ref36","doi-asserted-by":"publisher","first-page":"1339","DOI":"10.1007\/s00406-022-01514-5","article-title":"Long-lasting cognitive effects of COVID-19: is there a role of BDNF?","volume":"273","author":"Demir","year":"2023","journal-title":"Eur Arch Psychiatry Clin Neurosci"},{"key":"2026082709421145200_ref37","doi-asserted-by":"publisher","first-page":"96","DOI":"10.1016\/j.ijpsycho.2015.11.008","article-title":"Could BDNF be involved in compensatory mechanisms to maintain cognitive performance despite acute sleep deprivation? An exploratory study","volume":"99","author":"Giacobbo","year":"2016","journal-title":"Int J Psychophysiol"},{"key":"2026082709421145200_ref38","article-title":"Increased plasma brain-derived neurotrophic factor (BDNF) as a potential biomarker for and compensatory mechanism in mild cognitive impairment: a case-control study","author":"Kheng","year":"2021"},{"key":"2026082709421145200_ref39","doi-asserted-by":"publisher","DOI":"10.3390\/cells14070476","article-title":"BDNF Signaling and pain modulation","volume":"14","author":"Mazzitelli","year":"2025","journal-title":"Cells"},{"key":"2026082709421145200_ref40","doi-asserted-by":"publisher","DOI":"10.1007\/s11481-025-10180-y","article-title":"PKR inhibition prevents Neuroinflammation and rescues depressive-like Behaviors via BDNF\/TrkB Signaling","volume":"20","author":"Hu","year":"2025","journal-title":"J NeuroImmune Pharmacol"},{"key":"2026082709421145200_ref41","doi-asserted-by":"publisher","DOI":"10.3390\/ijms25073819","article-title":"The influence of microglia on neuroplasticity and long-term cognitive sequelae in long COVID: impacts on brain development and beyond","volume":"25","author":"S.","year":"2024","journal-title":"Int J Mol Sci"},{"key":"2026082709421145200_ref42","doi-asserted-by":"publisher","first-page":"1552","DOI":"10.1017\/S0007114522000551","article-title":"Consumption of ultra-processed foods and IL-6 in two cohorts from high- and middle-income countries","volume":"129","author":"Silva Dos Santos","year":"2023","journal-title":"Br J Nutr"},{"key":"2026082709421145200_ref43","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1093\/mutage\/geq050","article-title":"The effect of age, gender, diet and lifestyle on DNA damage measured using micronucleus frequency in human peripheral blood lymphocytes","volume":"26","author":"Fenech","year":"2011","journal-title":"Mutagenesis"},{"key":"2026082709421145200_ref44","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.jnutbio.2018.07.003","article-title":"Dietary modulation of mitochondrial DNA damage: implications in aging and associated diseases","volume":"63","author":"Lam","year":"2019","journal-title":"J Nutr Biochem"},{"key":"2026082709421145200_ref45","doi-asserted-by":"publisher","first-page":"568","DOI":"10.1017\/S0007114520001981","article-title":"Higher ultra-processed food intake is associated with higher DNA damage in healthy adolescents","volume":"125","author":"Edalati","year":"2021","journal-title":"Br J Nutr"},{"key":"2026082709421145200_ref46","doi-asserted-by":"crossref","first-page":"104399","DOI":"10.1016\/j.yrtph.2019.05.024","article-title":"In vitro and in vivo genotoxicity studies on monosodium L-glutamate monohydrate","volume":"107","author":"Takumi","year":"2019","journal-title":"Regul Toxicol Pharmacol"},{"key":"2026082709421145200_ref47","doi-asserted-by":"publisher","first-page":"115476","DOI":"10.1016\/j.fct.2025.115476","article-title":"Genotoxicity assessment of food-grade titanium dioxide","volume":"201","author":"Ling","year":"2025","journal-title":"Food Chem Toxicol"},{"key":"2026082709421145200_ref48","first-page":"503142","article-title":"Genotoxicity of the food additive E171, titanium dioxide, in the plants Lens culinaris L. and Allium cepa L. mutation research\/genetic toxicology and environmental","volume":"849","author":"Bellani","year":"2020","journal-title":"Mutagenesis"},{"key":"2026082709421145200_ref49","doi-asserted-by":"publisher","first-page":"763","DOI":"10.1016\/j.fct.2010.11.040","article-title":"The evaluation of the genotoxicity of two food preservatives: sodium benzoate and potassium benzoate","volume":"49","author":"Zengin","year":"2011","journal-title":"Food Chem Toxicol"},{"key":"2026082709421145200_ref50","doi-asserted-by":"publisher","DOI":"10.1590\/1519-6984.243628","article-title":"Antiproliferative, genotoxic and mutagenic potential of synthetic chocolate food flavoring","volume":"82","author":"Fr\u00e2ncica","year":"2022","journal-title":"Braz J Biol"},{"key":"2026082709421145200_ref51","doi-asserted-by":"publisher","first-page":"288","DOI":"10.1158\/2326-6066.CIR-14-0022","article-title":"The biology and medical implications of interleukin-6","volume":"2","author":"Tanaka","year":"2014","journal-title":"Cancer Immunol Res"},{"key":"2026082709421145200_ref52","doi-asserted-by":"publisher","DOI":"10.1016\/j.meegid.2025.105728","article-title":"Genotoxic risks in patients with COVID-19","volume":"129","author":"Ba\u015faran","year":"2025","journal-title":"Infect Genet Evol"},{"key":"2026082709421145200_ref53","doi-asserted-by":"publisher","first-page":"320","DOI":"10.5935\/1518-0557.20240007","article-title":"Implications of lifestyle factors on male reproductive health","volume":"28","author":"Rotimi","year":"2024","journal-title":"J Bras Reprod Assist"},{"key":"2026082709421145200_ref54","doi-asserted-by":"publisher","DOI":"10.3390\/ijms24021731","article-title":"Can baseline IL-6 levels predict long COVID in subjects hospitalized for SARS-CoV-2 disease?","volume":"24","author":"Giannitrapani","year":"2023","journal-title":"Int J Mol Sci"},{"key":"2026082709421145200_ref55","doi-asserted-by":"publisher","first-page":"4","DOI":"10.1111\/sms.14241","article-title":"IL-6 signaling in acute exercise and chronic training: potential consequences for health and athletic performance","volume":"33","author":"Nash","year":"2023","journal-title":"Scand J Med Sci Sports"},{"key":"2026082709421145200_ref56","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.mrgentox.2013.03.001","article-title":"The effect of age, sex, and lifestyle factors on micronucleus frequency in peripheral blood lymphocytes of the Bosnian population","volume":"753","author":"Nefic","year":"2013","journal-title":"Mutat Res Genet Toxicol Environ Mutagen"},{"key":"2026082709421145200_ref57","doi-asserted-by":"publisher","DOI":"10.1155\/2018\/7017423","article-title":"Occupational exposure to pesticides in tobacco fields: the integrated evaluation of nutritional intake and susceptibility on genomic and epigenetic instability","volume":"2018","author":"Kahl","year":"2018","journal-title":"Oxidative Med Cell Longev"},{"key":"2026082709421145200_ref58","doi-asserted-by":"publisher","DOI":"10.1016\/j.mrrev.2021.108367","article-title":"Impact of dietary and lifestyle interventions in elderly or people diagnosed with diabetes, metabolic disorders, cardiovascular disease, cancer and micronutrient deficiency on micronuclei frequency \u2013 a systematic review and meta-analysis","volume":"787","author":"Wagner","year":"2021","journal-title":"Mutat Res Rev Mutat Res"},{"key":"2026082709421145200_ref59","doi-asserted-by":"publisher","first-page":"383","DOI":"10.1016\/j.ypmed.2008.12.023","article-title":"Effects of lifestyle on micronuclei frequency in human lymphocytes in Japanese hard-metal workers","volume":"48","author":"Huang","year":"2009","journal-title":"Prev Med (Baltim)"},{"key":"2026082709421145200_ref60","doi-asserted-by":"publisher","first-page":"825","DOI":"10.1038\/nprot.2009.53","article-title":"Buccal micronucleus cytome assay","volume":"4","author":"Thomas","year":"2009","journal-title":"Nat Protoc"},{"key":"2026082709421145200_ref61","doi-asserted-by":"publisher","first-page":"240","DOI":"10.1016\/j.freeradbiomed.2025.03.047","article-title":"Plant-based diet and oxidative stress-induced DNA damage in post-surgery colorectal cancer patients: results from a randomized controlled trial","volume":"233","author":"Nordengen","year":"2025","journal-title":"Free Radic Biol Med"},{"key":"2026082709421145200_ref62","doi-asserted-by":"publisher","first-page":"421","DOI":"10.1038\/s41593-024-01576-9","article-title":"Blood\u2013brain barrier disruption and sustained systemic inflammation in individuals with long COVID-associated cognitive impairment","volume":"27","author":"Greene","year":"2024","journal-title":"Nat Neurosci"}],"container-title":["Mutagenesis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/mutage\/advance-article-pdf\/doi\/10.1093\/mutage\/geag020\/68334637\/geag020.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/mutage\/article-pdf\/41\/5\/271\/68334637\/geag020.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/mutage\/article-pdf\/41\/5\/271\/68334637\/geag020.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T13:42:22Z","timestamp":1787838142000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/mutage\/article\/41\/5\/271\/8687352"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,19]]},"references-count":62,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2026,5,19]]},"published-print":{"date-parts":[[2026,8,27]]}},"URL":"https:\/\/doi.org\/10.1093\/mutage\/geag020","relation":{},"ISSN":["0267-8357","1464-3804"],"issn-type":[{"value":"0267-8357","type":"print"},{"value":"1464-3804","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2026,9]]},"published":{"date-parts":[[2026,5,19]]}}}