{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T22:57:00Z","timestamp":1791068220908,"version":"4.1.0"},"reference-count":46,"publisher":"Oxford University Press (OUP)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Mutagenesis"],"published-print":{"date-parts":[[2012,9,1]]},"DOI":"10.1093\/mutage\/ges015","type":"journal-article","created":{"date-parts":[[2012,4,27]],"date-time":"2012-04-27T04:49:24Z","timestamp":1335502164000},"page":"523-532","source":"Crossref","is-referenced-by-count":46,"title":["Genotoxicity profile of fexinidazole--a drug candidate in clinical development for human African trypanomiasis (sleeping sickness)"],"prefix":"10.1093","volume":"27","author":[{"given":"D.","family":"Tweats","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.","family":"Bourdin Trunz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Torreele","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2012,4,26]]},"reference":[{"key":"2_42447530","first-page":"e55","volume":"5","year":"2006","ISSN":"https:\/\/id.crossref.org\/issn\/1549-1277","issn-type":"print"},{"issue":"7","key":"3_17156534","doi-asserted-by":"publisher","first-page":"437","DOI":"10.1016\/S1473-3099(02)00321-3","volume":"2","author":"Legros","year":"2002","journal-title":"The Lancet infectious diseases","ISSN":"https:\/\/id.crossref.org\/issn\/1473-3099","issn-type":"print"},{"issue":"6","key":"4_31221904","doi-asserted-by":"publisher","first-page":"966","DOI":"10.3201\/eid1406.71266","volume":"14","author":"Robays","year":"2008","journal-title":"Emerging infectious diseases","ISSN":"https:\/\/id.crossref.org\/issn\/1080-6040","issn-type":"print"},{"issue":"2","key":"5_16195550","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1016\/0001-706X(95)00109-R","volume":"60","author":"Bouteille","year":"1995","journal-title":"Acta tropica","ISSN":"https:\/\/id.crossref.org\/issn\/0001-706X","issn-type":"print"},{"issue":"2","key":"6_18194628","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/j.mrgentox.2004.02.013","volume":"560","author":"Nesslany","year":"2004","journal-title":"Mutation Research","ISSN":"https:\/\/id.crossref.org\/issn\/0027-5107","issn-type":"print"},{"key":"7_29686754","doi-asserted-by":"crossref","first-page":"S19","DOI":"10.1007\/s00436-002-0754-9","volume":"90","year":"2003","journal-title":"Parasitology research","ISSN":"https:\/\/id.crossref.org\/issn\/0932-0113","issn-type":"print"},{"issue":"9","key":"8_35255072","doi-asserted-by":"publisher","first-page":"2173","DOI":"10.1002\/ijc.24545","volume":"125","author":"Friedman","year":"2009","journal-title":"International journal of cancer. Journal international du cancer","ISSN":"https:\/\/id.crossref.org\/issn\/0020-7136","issn-type":"print"},{"issue":"2","key":"10_35104929","first-page":"106","volume":"22","author":"Granizo","year":"2009","journal-title":"Revista espa  ola de quimioterapia : publicaci  n oficial de la Sociedad Espa  ola de Quimioterapia","ISSN":"https:\/\/id.crossref.org\/issn\/0214-3429","issn-type":"print"},{"issue":"9723","key":"11_37133801","doi-asserted-by":"publisher","first-page":"1388","DOI":"10.1016\/S0140-6736(10)60061-X","volume":"375","author":"Rassi","year":"2010","journal-title":"Lancet","ISSN":"https:\/\/id.crossref.org\/issn\/0140-6736","issn-type":"print"},{"issue":"9743","key":"12_38084020","doi-asserted-by":"crossref","first-page":"768","DOI":"10.1016\/S0140-6736(10)61372-4","volume":"376","author":"Issa","year":"2010","journal-title":"Lancet","ISSN":"https:\/\/id.crossref.org\/issn\/0140-6736","issn-type":"print"},{"key":"13_42447531","first-page":"2009","volume":"2009","year":"2009","ISSN":"https:\/\/id.crossref.org\/issn\/2090-0031","issn-type":"print"},{"issue":"1","key":"14_31396371","doi-asserted-by":"publisher","first-page":"46","DOI":"10.1016\/j.toxlet.2008.05.017","volume":"180","author":"Lopez Nigro","year":"2008","journal-title":"Toxicology letters","ISSN":"https:\/\/id.crossref.org\/issn\/0378-4274","issn-type":"print"},{"issue":"13","key":"15_4954036","doi-asserted-by":"publisher","first-page":"2603","DOI":"10.1016\/0006-2952(88)90252-3","volume":"37","author":"Ehlhardt","year":"1988","journal-title":"Biochemical pharmacology","ISSN":"https:\/\/id.crossref.org\/issn\/0006-2952","issn-type":"print"},{"issue":"1","key":"16_10160133","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1093\/jac\/31.1.9","volume":"31","author":"Edwards","year":"1993","journal-title":"Journal of Antimicrobial Chemotherapy","ISSN":"https:\/\/id.crossref.org\/issn\/0305-7453","issn-type":"print"},{"key":"17_40714767","doi-asserted-by":"crossref","first-page":"497","DOI":"10.3797\/scipharm.0907-14","volume":"77","year":"2009","ISSN":"https:\/\/id.crossref.org\/issn\/0036-8709","issn-type":"print"},{"key":"18_42447532","first-page":"979","volume":"72","year":"1973","journal-title":"PNAS","ISSN":"https:\/\/id.crossref.org\/issn\/0027-8424","issn-type":"print"},{"issue":"12","key":"19_8247320","first-page":"4599","volume":"40","author":"Blumer","year":"1980","journal-title":"Cancer Research","ISSN":"https:\/\/id.crossref.org\/issn\/0008-5472","issn-type":"print"},{"issue":"4","key":"20_13641177","doi-asserted-by":"publisher","first-page":"429","DOI":"10.1002\/em.2860070404","volume":"7","author":"Speck","year":"1985","journal-title":"Environmental mutagenesis","ISSN":"https:\/\/id.crossref.org\/issn\/0192-2521","issn-type":"print"},{"key":"21_42447533","first-page":"150","volume":"30","year":"1986","journal-title":"Journal of medicinal chemistry","ISSN":"https:\/\/id.crossref.org\/issn\/0022-2623","issn-type":"print"},{"issue":"2","key":"22_9748295","doi-asserted-by":"publisher","first-page":"167","DOI":"10.1002\/em.2850190212","volume":"19","author":"De M\u00a0\u00a0o","year":"1992","journal-title":"Environmental and molecular mutagenesis","ISSN":"https:\/\/id.crossref.org\/issn\/0893-6692","issn-type":"print"},{"issue":"10","key":"23_28321258","doi-asserted-by":"publisher","first-page":"1537","DOI":"10.1016\/j.bcp.2007.01.024","volume":"73","author":"Buschini","year":"2007","journal-title":"Biochemical pharmacology","ISSN":"https:\/\/id.crossref.org\/issn\/0006-2952","issn-type":"print"},{"issue":"2","key":"24_31413381","doi-asserted-by":"publisher","first-page":"653","DOI":"10.1016\/j.ejmech.2008.05.015","volume":"44","author":"Crozet","year":"2009","journal-title":"European journal of medicinal chemistry","ISSN":"https:\/\/id.crossref.org\/issn\/0223-5234","issn-type":"print"},{"issue":"13","key":"25_30705841","doi-asserted-by":"publisher","first-page":"5022","DOI":"10.1073\/pnas.0711014105","volume":"105","year":"2008","journal-title":"PNAS","ISSN":"https:\/\/id.crossref.org\/issn\/0027-8424","issn-type":"print"},{"issue":"7","key":"26_37197776","doi-asserted-by":"publisher","first-page":"2893","DOI":"10.1128\/AAC.00332-10","volume":"54","year":"2010","journal-title":"Antimicrobial Agents and Chemotherapy","ISSN":"https:\/\/id.crossref.org\/issn\/0066-4804","issn-type":"print"},{"issue":"6789","key":"27_10375038","doi-asserted-by":"publisher","first-page":"962","DOI":"10.1038\/35016103","volume":"405","author":"Stover","year":"2000","journal-title":"Nature; Physical Science (London)","ISSN":"https:\/\/id.crossref.org\/issn\/1476-4687","issn-type":"print"},{"issue":"11","key":"28_23057260","doi-asserted-by":"publisher","first-page":"e466","DOI":"10.1371\/journal.pmed.0030466","volume":"3","author":"Matsumoto","year":"2006","ISSN":"https:\/\/id.crossref.org\/issn\/1549-1277","issn-type":"print"},{"key":"29_42447534","first-page":"739","volume":"28","year":"1978","journal-title":"ARZNEIMITTELFORSCHUNGDRUG RES"},{"issue":"1","key":"31_9062656","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1080\/00034983.1983.11811668","volume":"77","author":"Raether","year":"1983","journal-title":"Annals of tropical medicine and parasitology","ISSN":"https:\/\/id.crossref.org\/issn\/0003-4983","issn-type":"print"},{"issue":"12","key":"32_39070366","doi-asserted-by":"publisher","first-page":"e923","DOI":"10.1371\/journal.pntd.0000923","volume":"4","author":"Torreele","year":"2010","ISSN":"https:\/\/id.crossref.org\/issn\/1935-2735","issn-type":"print"},{"issue":"1","key":"33_16763496","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/S0027-5107(96)00243-6","volume":"375","author":"Yamada","year":"1997","journal-title":"Mutation Research","ISSN":"https:\/\/id.crossref.org\/issn\/0027-5107","issn-type":"print"},{"issue":"1-2","key":"34_11358633","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0027-5107(01)00239-1","volume":"483","author":"Porwollik","year":"2001","journal-title":"Mutation Research","ISSN":"https:\/\/id.crossref.org\/issn\/0027-5107","issn-type":"print"},{"issue":"3-4","key":"35_8936142","doi-asserted-by":"publisher","first-page":"173","DOI":"10.1016\/0165-1218(83)90165-9","volume":"113","author":"Maron","year":"1983","journal-title":"Mutation Research","ISSN":"https:\/\/id.crossref.org\/issn\/0027-5107","issn-type":"print"},{"issue":"1-2","key":"37_10580687","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/S0027-5107(00)00117-2","volume":"455","author":"Krishna","year":"2000","journal-title":"Mutation Research","ISSN":"https:\/\/id.crossref.org\/issn\/0027-5107","issn-type":"print"},{"issue":"7","key":"39_10769055","doi-asserted-by":"publisher","first-page":"3537","DOI":"10.1073\/pnas.96.7.3537","volume":"96","author":"Liochev","year":"1999","journal-title":"PNAS","ISSN":"https:\/\/id.crossref.org\/issn\/0027-8424","issn-type":"print"},{"key":"40_23841300","doi-asserted-by":"crossref","first-page":"1637","DOI":"10.1063\/1.555843","volume":"18","year":"1989","journal-title":"J PHYS CHEM REF DATA"},{"issue":"2","key":"41_16031459","doi-asserted-by":"publisher","first-page":"147","DOI":"10.1002\/em.2850260208","volume":"26","author":"Parton","year":"1995","journal-title":"Environmental and molecular mutagenesis","ISSN":"https:\/\/id.crossref.org\/issn\/0893-6692","issn-type":"print"},{"issue":"3","key":"42_8670382","doi-asserted-by":"publisher","first-page":"241","DOI":"10.1093\/carcin\/3.3.241","volume":"3","author":"Mirsalis","year":"1982","journal-title":"Carcinogenesis","ISSN":"https:\/\/id.crossref.org\/issn\/0143-3334","issn-type":"print"},{"issue":"26","key":"43_18522633","doi-asserted-by":"publisher","first-page":"3229","DOI":"10.2174\/1381612043383287","volume":"10","author":"Lounis","year":"2004","journal-title":"Current pharmaceutical design","ISSN":"https:\/\/id.crossref.org\/issn\/1381-6128","issn-type":"print"},{"key":"44_42447535","first-page":"58","volume":"93","year":"1983","journal-title":"Surgery","ISSN":"https:\/\/id.crossref.org\/issn\/0039-6060","issn-type":"print"},{"issue":"1","key":"45_10160133","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1093\/jac\/31.1.9","volume":"31","year":"1993","journal-title":"Journal of Antimicrobial Chemotherapy","ISSN":"https:\/\/id.crossref.org\/issn\/0305-7453","issn-type":"print"},{"key":"47_42447536","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1177\/030089168306900502","volume":"69","year":"1983","ISSN":"https:\/\/id.crossref.org\/issn\/2038-2529","issn-type":"print"},{"issue":"3","key":"48_42172178","doi-asserted-by":"publisher","first-page":"863","DOI":"10.1093\/jnci\/63.3.863","volume":"63","year":"1979","journal-title":"JNCI Journal of the National Cancer Institute","ISSN":"https:\/\/id.crossref.org\/issn\/0027-8874","issn-type":"print"},{"issue":"2","key":"49_14687834","doi-asserted-by":"publisher","first-page":"189","DOI":"10.1016\/0165-1218(94)90046-9","volume":"305","author":"Teixeira","year":"1994","journal-title":"Mutation Research","ISSN":"https:\/\/id.crossref.org\/issn\/0027-5107","issn-type":"print"},{"issue":"5-6","key":"50_22314876","doi-asserted-by":"publisher","first-page":"397","DOI":"10.1016\/j.etp.2006.01.005","volume":"57","author":"Iatropoulos","year":"2006","journal-title":"Experimental and toxicologic pathology : official journal of the Gesellschaft f  r Toxikologische Pathologie","ISSN":"https:\/\/id.crossref.org\/issn\/0940-2993","issn-type":"print"},{"issue":"2","key":"51_17144958","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/S1383-5718(02)00105-5","volume":"518","author":"Suter","year":"2002","journal-title":"Mutation Research","ISSN":"https:\/\/id.crossref.org\/issn\/0027-5107","issn-type":"print"},{"issue":"5","key":"52_39356381","doi-asserted-by":"publisher","first-page":"1524","DOI":"10.1016\/j.ejmech.2011.01.071","volume":"46","author":"Trunz","year":"2011","journal-title":"European journal of medicinal chemistry","ISSN":"https:\/\/id.crossref.org\/issn\/0223-5234","issn-type":"print"}],"container-title":["Mutagenesis"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/mutage\/article-pdf\/27\/5\/523\/3168513\/ges015.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,7,6]],"date-time":"2020-07-06T20:09:28Z","timestamp":1594066168000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/mutage\/article-lookup\/doi\/10.1093\/mutage\/ges015"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,4,26]]},"references-count":46,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2012,8,20]]},"published-print":{"date-parts":[[2012,9,1]]}},"URL":"https:\/\/doi.org\/10.1093\/mutage\/ges015","relation":{},"ISSN":["0267-8357","1464-3804"],"issn-type":[{"value":"0267-8357","type":"print"},{"value":"1464-3804","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,4,26]]}}}