{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,12]],"date-time":"2025-11-12T13:47:35Z","timestamp":1762955255272},"reference-count":39,"publisher":"Oxford University Press (OUP)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2014,3]]},"DOI":"10.1093\/mutage\/get067","type":"journal-article","created":{"date-parts":[[2014,1,17]],"date-time":"2014-01-17T03:15:41Z","timestamp":1389928541000},"page":"107-114","source":"Crossref","is-referenced-by-count":11,"title":["An increase of oxidised nucleotides activates DNA damage checkpoint pathway that regulates post-embryonic development in Caenorhabditis elegans"],"prefix":"10.1093","volume":"29","author":[{"given":"Yu","family":"Sanada","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qiu-Mei","family":"Zhang-Akiyama","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2014,1,16]]},"reference":[{"key":"key\n\t\t\t\t20170517095000_CIT0001","doi-asserted-by":"crossref","first-page":"1195","DOI":"10.1096\/fj.02-0752rev","article-title":"Oxidative DNA damage: mechanisms, mutation, and disease","volume":"17","author":"Cooke","year":"(2003)","journal-title":"FASEB J."},{"key":"key\n\t\t\t\t20170517095000_CIT0002","doi-asserted-by":"crossref","first-page":"8895","DOI":"10.1038\/sj.onc.1206023","article-title":"Oxidative nucleotide damage: consequences and prevention","volume":"21","author":"Sekiguchi","year":"(2002)","journal-title":"Oncogene"},{"key":"key\n\t\t\t\t20170517095000_CIT0003","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1038\/327077a0","article-title":"Misreading of DNA templates containing 8-hydroxydeoxyguanosine at the modified base and at adjacent residues","volume":"327","author":"Kuchino","year":"(1987)","journal-title":"Nature"},{"key":"key\n\t\t\t\t20170517095000_CIT0004","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/S0300-483X(00)00140-2","article-title":"Induction of 8-oxo-dGTPase activity in human lymphoid cells and normal fibroblasts by oxidative stress","volume":"146","author":"Meyer","year":"(2000)","journal-title":"Toxicology"},{"key":"key\n\t\t\t\t20170517095000_CIT0005","doi-asserted-by":"crossref","first-page":"11021","DOI":"10.1073\/pnas.89.22.11021","article-title":"Hydrolytic elimination of a mutagenic nucleotide, 8-oxodGTP, by human 18-kilodalton protein: sanitization of nucleotide pool","volume":"89","author":"Mo","year":"(1992)","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"key\n\t\t\t\t20170517095000_CIT0006","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1038\/355273a0","article-title":"MutT protein specifically hydrolyses a potent mutagenic substrate for DNA synthesis","volume":"355","author":"Maki","year":"(1992)","journal-title":"Nature"},{"key":"key\n\t\t\t\t20170517095000_CIT0007","doi-asserted-by":"crossref","first-page":"23524","DOI":"10.1016\/S0021-9258(19)49494-5","article-title":"Cloning and expression of cDNA for a human enzyme that hydrolyzes 8-oxo-dGTP, a mutagenic substrate for DNA synthesis","volume":"268","author":"Sakumi","year":"(1993)","journal-title":"J. Biol. Chem."},{"key":"key\n\t\t\t\t20170517095000_CIT0008","doi-asserted-by":"crossref","first-page":"1073","DOI":"10.1016\/S0006-291X(03)00864-7","article-title":"Mouse MTH2 protein which prevents mutations caused by 8-oxoguanine nucleotides","volume":"305","author":"Cai","year":"(2003)","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"key\n\t\t\t\t20170517095000_CIT0009","doi-asserted-by":"crossref","first-page":"21541","DOI":"10.1074\/jbc.M112.363010","article-title":"Human MTH3 (NUDT18) protein hydrolyzes oxidized forms of guanosine and deoxyguanosine diphosphates: comparison with MTH1 and MTH2","volume":"287","author":"Takagi","year":"(2012)","journal-title":"J. Biol. Chem."},{"key":"key\n\t\t\t\t20170517095000_CIT0010","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1038\/sj.embor.embor838","article-title":"A novel mechanism for preventing mutations caused by oxidation of guanine nucleotides","volume":"4","author":"Ishibashi","year":"(2003)","journal-title":"EMBO Rep."},{"key":"key\n\t\t\t\t20170517095000_CIT0011","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1093\/jb\/mvr107","article-title":"NDX-1 protein hydrolyzes 8-oxo-7, 8-dihydrodeoxyguanosine-5\u2019-diphosphate to sanitize oxidized nucleotides and prevent oxidative stress in Caenorhabditis elegans","volume":"150","author":"Sanada","year":"(2011)","journal-title":"J. Biochem."},{"key":"key\n\t\t\t\t20170517095000_CIT0012","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1016\/j.dnarep.2010.10.009","article-title":"Caenorhabditis elegans NDX-4 is a MutT-type enzyme that contributes to genomic stability","volume":"10","author":"Arczewska","year":"(2011)","journal-title":"DNA Repair (Amst)."},{"key":"key\n\t\t\t\t20170517095000_CIT0013","doi-asserted-by":"crossref","first-page":"9977","DOI":"10.1021\/bi010595q","article-title":"Specific binding of 8-oxoguanine-containing RNA to polynucleotide phosphorylase protein","volume":"40","author":"Hayakawa","year":"(2001)","journal-title":"Biochemistry"},{"key":"key\n\t\t\t\t20170517095000_CIT0014","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1126\/science.278.5335.128","article-title":"Counteraction by MutT protein of transcriptional errors caused by oxidative damage","volume":"278","author":"Taddei","year":"(1997)","journal-title":"Science"},{"key":"key\n\t\t\t\t20170517095000_CIT0015","doi-asserted-by":"crossref","first-page":"6670","DOI":"10.1021\/bi047550k","article-title":"Multiple enzyme activities of Escherichia coli MutT protein for sanitization of DNA and RNA precursor pools","volume":"44","author":"Ito","year":"(2005)","journal-title":"Biochemistry"},{"key":"key\n\t\t\t\t20170517095000_CIT0016","doi-asserted-by":"crossref","first-page":"3779","DOI":"10.1093\/nar\/gki682","article-title":"Mammalian enzymes for preventing transcriptional errors caused by oxidative damage","volume":"33","author":"Ishibashi","year":"(2005)","journal-title":"Nucleic Acids Res."},{"key":"key\n\t\t\t\t20170517095000_CIT0017","doi-asserted-by":"crossref","first-page":"1160","DOI":"10.1126\/science.1140321","article-title":"ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage","volume":"316","author":"Matsuoka","year":"(2007)","journal-title":"Science"},{"key":"key\n\t\t\t\t20170517095000_CIT0018","doi-asserted-by":"crossref","first-page":"2565","DOI":"10.1242\/dev.01136","article-title":"A Werner syndrome protein homolog affects C. elegans development, growth rate, life span and sensitivity to DNA damage by acting at a DNA damage checkpoint","volume":"131","author":"Lee","year":"(2004)","journal-title":"Development"},{"key":"key\n\t\t\t\t20170517095000_CIT0019","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.mrfmmm.2008.11.007","article-title":"C. elegans: a model of Fanconi anemia and ICL repair","volume":"668","author":"Youds","year":"(2009)","journal-title":"Mutat. Res."},{"key":"key\n\t\t\t\t20170517095000_CIT0020","doi-asserted-by":"crossref","first-page":"1046","DOI":"10.1038\/sj.embor.7400782","article-title":"Abrogation of the CLK-2 checkpoint leads to tolerance to base-excision repair intermediates","volume":"7","author":"Dengg","year":"(2006)","journal-title":"EMBO Rep."},{"key":"key\n\t\t\t\t20170517095000_CIT0021","doi-asserted-by":"crossref","first-page":"941","DOI":"10.1038\/nature05978","article-title":"Base-excision repair of oxidative DNA damage","volume":"447","author":"David","year":"(2007)","journal-title":"Nature"},{"key":"key\n\t\t\t\t20170517095000_CIT0022","doi-asserted-by":"crossref","first-page":"6321","DOI":"10.1128\/jb.174.20.6321-6325.1992","article-title":"The GO system protects organisms from the mutagenic effect of the spontaneous lesion 8-hydroxyguanine (7,8-dihydro-8-oxoguanine)","volume":"174","author":"Michaels","year":"(1992)","journal-title":"J. Bacteriol."},{"key":"key\n\t\t\t\t20170517095000_CIT0023","doi-asserted-by":"crossref","first-page":"5197","DOI":"10.1073\/pnas.93.11.5197","article-title":"Cloning and expression in Escherichia coli of the OGG1 gene of Saccharomyces cerevisiae, which codes for a DNA glycosylase that excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N-methylformamidopyrimidine","volume":"93","author":"van der Kemp","year":"(1996)","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"key\n\t\t\t\t20170517095000_CIT0024","doi-asserted-by":"crossref","first-page":"8010","DOI":"10.1073\/pnas.94.15.8010","article-title":"Cloning and characterization of hOGG1, a human homolog of the OGG1 gene of Saccharomyces cerevisiae","volume":"94","author":"Radicella","year":"(1997)","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"key\n\t\t\t\t20170517095000_CIT0025","doi-asserted-by":"crossref","first-page":"854","DOI":"10.1038\/27579","article-title":"Specific interference by ingested dsRNA","volume":"395","author":"Timmons","year":"(1998)","journal-title":"Nature"},{"key":"key\n\t\t\t\t20170517095000_CIT0026","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/S1046-2023(03)00050-1","article-title":"Genome-wide RNAi screening in Caenorhabditis elegans","volume":"30","author":"Kamath","year":"(2003)","journal-title":"Methods"},{"key":"key\n\t\t\t\t20170517095000_CIT0027","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1016\/S0891-5849(03)00362-9","article-title":"Inhibition of 8-oxo-2\u2019-deoxyguanosine 5\u2019-triphosphate pyrophosphohydrolase (8-oxo-dGTPase) activity of the antimutagenic human MTH1 protein by nucleoside 5\u2019-diphosphates","volume":"35","author":"Bialkowski","year":"(2003)","journal-title":"Free Radic. Biol. Med."},{"key":"key\n\t\t\t\t20170517095000_CIT0028","doi-asserted-by":"crossref","first-page":"3523","DOI":"10.1073\/pnas.062053799","article-title":"Identification and characterization of a human DNA glycosylase for repair of modified bases in oxidatively damaged DNA","volume":"99","author":"Hazra","year":"(2002)","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"key\n\t\t\t\t20170517095000_CIT0029","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1471-2164-10-S1-S1","article-title":"Identification of genes expressed in the hermaphrodite germ line of C. elegans using SAGE","volume":"10","author":"Wang","year":"(2009)","journal-title":"BMC Genomics"},{"key":"key\n\t\t\t\t20170517095000_CIT0030","doi-asserted-by":"crossref","first-page":"33811","DOI":"10.1074\/jbc.273.50.33811","article-title":"Repair pathways for processing of 8-oxoguanine in DNA by mammalian cell extracts","volume":"273","author":"Dianov","year":"(1998)","journal-title":"J. Biol. Chem."},{"key":"key\n\t\t\t\t20170517095000_CIT0031","doi-asserted-by":"crossref","first-page":"912","DOI":"10.1016\/S0960-9822(02)00863-1","article-title":"The mammalian mismatch repair pathway removes DNA 8-oxodGMP incorporated from the oxidized dNTP pool","volume":"12","author":"Colussi","year":"(2002)","journal-title":"Curr. Biol."},{"key":"key\n\t\t\t\t20170517095000_CIT0032","doi-asserted-by":"crossref","first-page":"1244","DOI":"10.1016\/S0891-5849(02)00822-5","article-title":"Repair of 8-oxoguanine in Saccharomyces cerevisiae: interplay of DNA repair and replication mechanisms","volume":"32","author":"Boiteux","year":"(2002)","journal-title":"Free Radic. Biol. Med."},{"key":"key\n\t\t\t\t20170517095000_CIT0033","doi-asserted-by":"crossref","first-page":"844","DOI":"10.1016\/j.dnarep.2009.04.020","article-title":"Purification and characterization of Caenorhabditis elegans NTH, a homolog of human endonuclease III: essential role of N-terminal region","volume":"8","author":"Morinaga","year":"(2009)","journal-title":"DNA Repair (Amst)."},{"key":"key\n\t\t\t\t20170517095000_CIT0034","doi-asserted-by":"crossref","first-page":"133","DOI":"10.18632\/aging.100127","article-title":"A two-tiered compensatory response to loss of DNA repair modulates aging and stress response pathways","volume":"2","author":"Fensg\u00e5rd","year":"(2010)","journal-title":"Aging (Albany. NY)."},{"key":"key\n\t\t\t\t20170517095000_CIT0035","doi-asserted-by":"crossref","first-page":"2184","DOI":"10.1093\/nar\/26.9.2184","article-title":"Efficient in vitro repair of 7-hydro-8-oxodeoxyguanosine by human cell extracts: involvement of multiple pathways","volume":"26","author":"Jaiswal","year":"(1998)","journal-title":"Nucleic Acids Res."},{"key":"key\n\t\t\t\t20170517095000_CIT0036","doi-asserted-by":"crossref","first-page":"6335","DOI":"10.1073\/pnas.90.13.6335","article-title":"DNA excision-repair defect of xeroderma pigmentosum prevents removal of a class of oxygen free radical-induced base lesions","volume":"90","author":"Satoh","year":"(1993)","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"key\n\t\t\t\t20170517095000_CIT0037","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/j.dnarep.2007.10.004","article-title":"Nucleotide excision repair and the degradation of RNA pol II by the Caenorhabditis elegans XPA and Rsp5 orthologues, RAD-3 and WWP-1","volume":"7","author":"Astin","year":"(2008)","journal-title":"DNA Repair (Amst)."},{"key":"key\n\t\t\t\t20170517095000_CIT0038","doi-asserted-by":"crossref","first-page":"12419","DOI":"10.1016\/S0021-9258(18)33730-X","article-title":"The metabolism of menadione (2-methyl-1,4-naphthoquinone) by isolated hepatocytes. A study of the implications of oxidative stress in intact cells","volume":"257","author":"Thor","year":"(1982)","journal-title":"J. Biol. Chem."},{"key":"key\n\t\t\t\t20170517095000_CIT0039","doi-asserted-by":"crossref","first-page":"672","DOI":"10.1093\/nar\/gki214","article-title":"A functional analysis of the DNA glycosylase activity of mouse MUTYH protein excising 2-hydroxyadenine opposite guanine in DNA","volume":"33","author":"Ushijima","year":"(2005)","journal-title":"Nucleic Acids Res."}],"container-title":["Mutagenesis"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/mutage\/article-pdf\/29\/2\/107\/17162975\/get067.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,23]],"date-time":"2022-03-23T23:26:47Z","timestamp":1648078007000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/mutage\/article-lookup\/doi\/10.1093\/mutage\/get067"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,1,16]]},"references-count":39,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2014,1,16]]},"published-print":{"date-parts":[[2014,3]]}},"URL":"https:\/\/doi.org\/10.1093\/mutage\/get067","relation":{},"ISSN":["1464-3804","0267-8357"],"issn-type":[{"value":"1464-3804","type":"electronic"},{"value":"0267-8357","type":"print"}],"subject":[],"published":{"date-parts":[[2014,1,16]]}}}