{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T10:28:15Z","timestamp":1792146495692,"version":"4.4.0"},"reference-count":39,"publisher":"Oxford University Press (OUP)","license":[{"start":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T00:00:00Z","timestamp":1791158400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100006489","name":"French Alternative Energies and Atomic Energy Commission","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100006489","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Horizon Europe Program","award":["101082304"],"award-info":[{"award-number":["101082304"]}]},{"name":"Priority Antibiotic Resistance Research Program"},{"name":"General Secretariat for Investment"},{"name":"Agence Nationale pour la Recherche","award":["ANR-25-CE45-7210"],"award-info":[{"award-number":["ANR-25-CE45-7210"]}]},{"name":"Agence Nationale pour la Recherche under France 2030","award":["ANR-21-ESRE-0048"],"award-info":[{"award-number":["ANR-21-ESRE-0048"]}]},{"name":"ABRomics"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>PanGBank (https:\/\/pangbank.genoscope.cns.fr) is a comprehensive open-access database providing precomputed prokaryotic pangenomes at a broad taxonomic scale. Built upon PPanGGOLiN partitioned pangenome graphs, PanGBank addresses the growing need for large-scale comparative genomics through a standardized, regularly updated, and fully accessible resource. The initial release comprises two complementary collections covering &amp;gt;4600 prokaryotic species from the Genome Taxonomy Database (GTDB), encompassing over 393\u2009000 genomes: GTDB_all, maximizing taxonomic and environmental diversity through the inclusion of metagenome-assembled genomes and single-cell amplified genomes, and GTDB_refseq, focusing on high-quality, annotation-rich genomes. Each species-level pangenome integrates graph-based statistical partitions into persistent, shell, and cloud gene families, together with regions of genomic plasticity (panRGP) and co-localized functional modules (panModule). PanGBank offers multiple access modes, including a REST API, a command-line interface, and an interactive web interface. By combining large-scale pangenome resources with advanced graph-based analyses, PanGBank provides a scalable framework for exploring microbial diversity, genome evolution, functional variation, and the dissemination of adaptive traits across prokaryotic populations, as illustrated by a use case on Acinetobacter baumannii pangenome investigating the distribution and evolution of antimicrobial resistance determinants.<\/jats:p>","DOI":"10.1093\/nar\/gkag948","type":"journal-article","created":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T11:12:42Z","timestamp":1789989162000},"source":"Crossref","is-referenced-by-count":1,"title":["PanGBank: a large-scale resource of precomputed microbial pangenomes built with PPanGGOLiN"],"prefix":"10.1093","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-9160-9744","authenticated-orcid":false,"given":"Jean","family":"Mainguy","sequence":"first","affiliation":[{"name":"LABGeM, G\u00e9nomique M\u00e9tabolique, CEA, Genoscope, Institut 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