{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,8,5]],"date-time":"2024-08-05T14:44:26Z","timestamp":1722869066131},"reference-count":83,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2016,11,7]],"date-time":"2016-11-07T00:00:00Z","timestamp":1478476800000},"content-version":"vor","delay-in-days":1397,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2013,3]]},"DOI":"10.1093\/nar\/gks1470","type":"journal-article","created":{"date-parts":[[2013,1,12]],"date-time":"2013-01-12T01:56:23Z","timestamp":1357955783000},"page":"3032-3046","source":"Crossref","is-referenced-by-count":12,"title":["MSH6- or PMS2-deficiency causes re-replication in DT40 B cells, but it has little effect on immunoglobulin gene conversion or on repair of AID-generated uracils"],"prefix":"10.1093","volume":"41","author":[{"given":"Vanina A.","family":"Campo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anne-Marie","family":"Patenaude","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Svenja","family":"Kaden","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lori","family":"Horb","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel","family":"Firka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Josef","family":"Jiricny","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Javier M.","family":"Di Noia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2013,1,10]]},"reference":[{"key":"key\n\t\t\t\t20170512121855_gks1470-B1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1146\/annurev.biochem.76.061705.090740","article-title":"Molecular mechanisms of antibody somatic hypermutation","volume":"76","author":"Di Noia","year":"2007","journal-title":"Annu. Rev. Biochem."},{"key":"key\n\t\t\t\t20170512121855_gks1470-B2","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1146\/annurev.immunol.26.021607.090236","article-title":"The biochemistry of somatic hypermutation","volume":"26","author":"Peled","year":"2008","journal-title":"Annu. Rev. Immunol."},{"key":"key\n\t\t\t\t20170512121855_gks1470-B3","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1016\/0092-8674(87)90189-9","article-title":"A hyperconversion mechanism generates the chicken light chain preimmune repertoire","volume":"48","author":"Reynaud","year":"1987","journal-title":"Cell"},{"key":"key\n\t\t\t\t20170512121855_gks1470-B4","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/0092-8674(89)90879-9","article-title":"Somatic hyperconversion diversifies the single Vh gene of the chicken with a high incidence in the D region","volume":"59","author":"Reynaud","year":"1989","journal-title":"Cell"},{"key":"key\n\t\t\t\t20170512121855_gks1470-B5","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1038\/nri1395","article-title":"Class-switch recombination: interplay of transcription, DNA deamination and DNA repair","volume":"4","author":"Chaudhuri","year":"2004","journal-title":"Nat. Rev. Immunol."},{"key":"key\n\t\t\t\t20170512121855_gks1470-B6","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1146\/annurev.immunol.26.021607.090248","article-title":"Mechanism and regulation of class switch recombination","volume":"26","author":"Stavnezer","year":"2008","journal-title":"Annu. Rev. Immunol."},{"key":"key\n\t\t\t\t20170512121855_gks1470-B7","doi-asserted-by":"crossref","first-page":"1301","DOI":"10.1126\/science.1067308","article-title":"Requirement of the activation-induced deaminase (AID) gene for immunoglobulin gene conversion","volume":"295","author":"Arakawa","year":"2002","journal-title":"Science"},{"key":"key\n\t\t\t\t20170512121855_gks1470-B8","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1016\/S0960-9822(02)00717-0","article-title":"AID is essential for immunoglobulin V gene conversion in a cultured B cell line","volume":"12","author":"Harris","year":"2002","journal-title":"Curr. Biol."},{"key":"key\n\t\t\t\t20170512121855_gks1470-B9","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1016\/S0092-8674(00)00078-7","article-title":"Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme","volume":"102","author":"Muramatsu","year":"2000","journal-title":"Cell"},{"key":"key\n\t\t\t\t20170512121855_gks1470-B10","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1038\/nature00981","article-title":"Altering the pathway of immunoglobulin hypermutation by inhibiting uracil-DNA glycosylase","volume":"419","author":"Di Noia","year":"2002","journal-title":"Nature"},{"key":"key\n\t\t\t\t20170512121855_gks1470-B11","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.molcel.2004.10.011","article-title":"Mismatch recognition and uracil excision provide complementary paths to both Ig switching and the A\/T-focused phase of somatic mutation","volume":"16","author":"Rada","year":"2004","journal-title":"Mol. Cell"},{"key":"key\n\t\t\t\t20170512121855_gks1470-B12","doi-asserted-by":"crossref","first-page":"1748","DOI":"10.1016\/S0960-9822(02)01215-0","article-title":"Immunoglobulin isotype switching is inhibited and somatic hypermutation perturbed in UNG-deficient mice","volume":"12","author":"Rada","year":"2002","journal-title":"Curr. Biol."},{"key":"key\n\t\t\t\t20170512121855_gks1470-B13","doi-asserted-by":"crossref","first-page":"3209","DOI":"10.1084\/jem.20071768","article-title":"Dependence of antibody gene diversification on uracil excision","volume":"204","author":"Di Noia","year":"2007","journal-title":"J. Exp. Med."},{"key":"key\n\t\t\t\t20170512121855_gks1470-B14","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/S1074-7613(00)80595-6","article-title":"Hot spot focusing of somatic hypermutation in MSH2-deficient mice suggests two stages of mutational targeting","volume":"9","author":"Rada","year":"1998","journal-title":"Immunity"},{"key":"key\n\t\t\t\t20170512121855_gks1470-B15","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1038\/nrm1907","article-title":"The multifaceted mismatch-repair system","volume":"7","author":"Jiricny","year":"2006","journal-title":"Nat. Rev. Mol. Cell. Biol."},{"key":"key\n\t\t\t\t20170512121855_gks1470-B16","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1146\/annurev.biochem.74.082803.133243","article-title":"DNA mismatch repair","volume":"74","author":"Kunkel","year":"2005","journal-title":"Annu. Rev. Biochem."},{"key":"key\n\t\t\t\t20170512121855_gks1470-B17","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.tig.2005.11.002","article-title":"Mismatch repair converts AID-instigated nicks to double-strand breaks for antibody class-switch recombination","volume":"22","author":"Stavnezer","year":"2006","journal-title":"Trends Genet."},{"key":"key\n\t\t\t\t20170512121855_gks1470-B18","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1038\/ni1031","article-title":"Altered somatic hypermutation and reduced class-switch recombination in exonuclease 1-mutant mice","volume":"5","author":"Bardwell","year":"2004","journal-title":"Nat. Immunol."},{"key":"key\n\t\t\t\t20170512121855_gks1470-B19","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1084\/jem.20062131","article-title":"DNA polymerase eta is the sole contributor of A\/T modifications during immunoglobulin gene hypermutation in the mouse","volume":"204","author":"Delbos","year":"2007","journal-title":"J. Exp. Med."},{"key":"key\n\t\t\t\t20170512121855_gks1470-B20","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1038\/88740","article-title":"DNA polymerase eta is an A-T mutator in somatic hypermutation of immunoglobulin variable genes","volume":"2","author":"Zeng","year":"2001","journal-title":"Nat. Immunol."},{"key":"key\n\t\t\t\t20170512121855_gks1470-B21","doi-asserted-by":"crossref","first-page":"1989","DOI":"10.1084\/jem.20070902","article-title":"A\/T mutagenesis in hypermutated immunoglobulin genes strongly depends on PCNAK164 modification","volume":"204","author":"Langerak","year":"2007","journal-title":"J. Exp. Med."},{"key":"key\n\t\t\t\t20170512121855_gks1470-B22","doi-asserted-by":"crossref","first-page":"16248","DOI":"10.1073\/pnas.0808182105","article-title":"Ubiquitylated PCNA plays a role in somatic hypermutation and class-switch recombination and is required for meiotic progression","volume":"105","author":"Roa","year":"2008","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"key\n\t\t\t\t20170512121855_gks1470-B23","doi-asserted-by":"crossref","first-page":"14553","DOI":"10.1073\/pnas.241525998","article-title":"Switch junction sequences in PMS2-deficient mice reveal a microhomology-mediated mechanism of Ig class switch recombination","volume":"98","author":"Ehrenstein","year":"2001","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"key\n\t\t\t\t20170512121855_gks1470-B24","doi-asserted-by":"crossref","first-page":"5386","DOI":"10.4049\/jimmunol.177.8.5386","article-title":"Somatic hypermutation and class switch recombination in Msh6(\u2212\/\u2212)Ung(\u2212\/\u2212) double-knockout mice","volume":"177","author":"Shen","year":"2006","journal-title":"J. Immunol."},{"key":"key\n\t\t\t\t20170512121855_gks1470-B25","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1002\/dvdy.10495","article-title":"Immunoglobulin gene conversion: insights from bursal B cells and the DT40 cell line","volume":"229","author":"Arakawa","year":"2004","journal-title":"Dev. Dyn."},{"key":"key\n\t\t\t\t20170512121855_gks1470-B26","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1016\/1074-7613(94)90036-1","article-title":"Rabbit IgH sequences in appendix germinal centers: VH diversification by gene conversion-like and hypermutation mechanisms","volume":"1","author":"Weinstein","year":"1994","journal-title":"Immunity"},{"key":"key\n\t\t\t\t20170512121855_gks1470-B27","doi-asserted-by":"crossref","first-page":"548","DOI":"10.1101\/gad.4.4.548","article-title":"Chicken IgL variable region gene conversions display pseudogene donor preference and 5' to 3' polarity","volume":"4","author":"McCormack","year":"1990","journal-title":"Genes Dev."},{"key":"key\n\t\t\t\t20170512121855_gks1470-B28","doi-asserted-by":"crossref","first-page":"921","DOI":"10.1002\/j.1460-2075.1990.tb08190.x","article-title":"Light chain gene conversion continues at high rate in an ALV-induced cell line","volume":"9","author":"Buerstedde","year":"1990","journal-title":"EMBO J."},{"key":"key\n\t\t\t\t20170512121855_gks1470-B29","doi-asserted-by":"crossref","first-page":"3224","DOI":"10.1128\/MCB.10.6.3224","article-title":"Ongoing diversification of the rearranged immunoglobulin light-chain gene in a bursal lymphoma cell line","volume":"10","author":"Kim","year":"1990","journal-title":"Mol. Cell. Biol."},{"key":"key\n\t\t\t\t20170512121855_gks1470-B30","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1098\/rstb.2008.0202","article-title":"Activation-induced cytidine deaminase-mediated hypermutation in the DT40 cell line","volume":"364","author":"Arakawa","year":"2009","journal-title":"Philos. Trans. R Soc. Lond. B Biol. Sci."},{"key":"key\n\t\t\t\t20170512121855_gks1470-B31","doi-asserted-by":"crossref","first-page":"1557","DOI":"10.1016\/j.dnarep.2007.05.002","article-title":"Immunoglobulin gene conversion: Synthesizing antibody diversification and DNA repair","volume":"6","author":"Tang","year":"2007","journal-title":"DNA Repair (Amst)"},{"key":"key\n\t\t\t\t20170512121855_gks1470-B32","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1098\/rstb.2000.0755","article-title":"Reverse genetic studies of homologous DNA recombination using the chicken B-lymphocyte line, DT40","volume":"356","author":"Sonoda","year":"2001","journal-title":"Philos. Trans. R Soc. Lond. B Biol. Sci."},{"key":"key\n\t\t\t\t20170512121855_gks1470-B33","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1016\/j.dnarep.2004.03.042","article-title":"Immunoglobulin diversification in DT40: a model for vertebrate DNA damage tolerance","volume":"3","author":"Sale","year":"2004","journal-title":"DNA Repair (Amst)"},{"key":"key\n\t\t\t\t20170512121855_gks1470-B34","doi-asserted-by":"crossref","first-page":"921","DOI":"10.1038\/35091100","article-title":"Ablation of XRCC2\/3 transforms immunoglobulin V gene conversion into somatic hypermutation","volume":"412","author":"Sale","year":"2001","journal-title":"Nature"},{"key":"key\n\t\t\t\t20170512121855_gks1470-B35","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/j.dnarep.2007.10.002","article-title":"Brca1 in immunoglobulin gene conversion and somatic hypermutation","volume":"7","author":"Longerich","year":"2008","journal-title":"DNA Repair (Amst)"},{"key":"key\n\t\t\t\t20170512121855_gks1470-B36","doi-asserted-by":"crossref","first-page":"1124","DOI":"10.1128\/MCB.25.3.1124-1134.2005","article-title":"Similar effects of Brca2 truncation and Rad51 paralog deficiency on immunoglobulin V gene diversification in DT40 cells support an early role for Rad51 paralogs in homologous recombination","volume":"25","author":"Hatanaka","year":"2005","journal-title":"Mol. Cell. Biol."},{"key":"key\n\t\t\t\t20170512121855_gks1470-B37","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/S0092-8674(00)80198-1","article-title":"Reduced X-ray resistance and homologous recombination frequencies in a RAD54\u2212\/\u2212 mutant of the chicken DT40 cell line","volume":"89","author":"Bezzubova","year":"1997","journal-title":"Cell"},{"key":"key\n\t\t\t\t20170512121855_gks1470-B38","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1002\/eji.200324631","article-title":"Immunoglobulin gene conversion in chicken DT40 cells largely proceeds through an abasic site intermediate generated by excision of the uracil produced by AID-mediated deoxycytidine deamination","volume":"34","author":"Di Noia","year":"2004","journal-title":"Eur. J. Immunol."},{"key":"key\n\t\t\t\t20170512121855_gks1470-B39","doi-asserted-by":"crossref","first-page":"365","DOI":"10.4049\/jimmunol.176.1.365","article-title":"Uracil DNA glycosylase disruption blocks Ig gene conversion and induces transition mutations","volume":"176","author":"Saribasak","year":"2006","journal-title":"J. Immunol."},{"key":"key\n\t\t\t\t20170512121855_gks1470-B40","doi-asserted-by":"crossref","first-page":"e11182","DOI":"10.1371\/journal.pone.0011182","article-title":"MSH2\/MSH6 complex promotes error-free repair of AID-induced dU:G mispairs as well as error-prone hypermutation of A:T sites","volume":"5","author":"Roa","year":"2010","journal-title":"PLoS One"},{"key":"key\n\t\t\t\t20170512121855_gks1470-B41","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1128\/MCB.20.1.149-157.2000","article-title":"Genetic analysis of mouse embryonic stem cells bearing Msh3 and Msh2 single and compound mutations","volume":"20","author":"Abuin","year":"2000","journal-title":"Mol. Cell. Biol."},{"key":"key\n\t\t\t\t20170512121855_gks1470-B42","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1016\/0092-8674(95)90319-4","article-title":"Inactivation of the mouse Msh2 gene results in mismatch repair deficiency, methylation tolerance, hyperrecombination, and predisposition to cancer","volume":"82","author":"de Wind","year":"1995","journal-title":"Cell"},{"key":"key\n\t\t\t\t20170512121855_gks1470-B43","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1038\/15544","article-title":"HNPCC-like cancer predisposition in mice through simultaneous loss of Msh3 and Msh6 mismatch-repair protein functions","volume":"23","author":"de Wind","year":"1999","journal-title":"Nat. Genet."},{"key":"key\n\t\t\t\t20170512121855_gks1470-B44","doi-asserted-by":"crossref","first-page":"2671","DOI":"10.1128\/MCB.21.8.2671-2682.2001","article-title":"Repair of double-strand breaks by homologous recombination in mismatch repair-defective mammalian cells","volume":"21","author":"Elliott","year":"2001","journal-title":"Mol. Cell. Biol."},{"key":"key\n\t\t\t\t20170512121855_gks1470-B45","doi-asserted-by":"crossref","first-page":"7839","DOI":"10.1128\/MCB.20.21.7839-7844.2000","article-title":"Roles for mismatch repair factors in regulating genetic recombination","volume":"20","author":"Evans","year":"2000","journal-title":"Mol. Cell. Biol."},{"key":"key\n\t\t\t\t20170512121855_gks1470-B46","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1038\/nrg2193","article-title":"Gene conversion: mechanisms, evolution and human disease","volume":"8","author":"Chen","year":"2007","journal-title":"Nat. Rev. Genet."},{"key":"key\n\t\t\t\t20170512121855_gks1470-B47","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1098\/rstb.2003.1367","article-title":"Repairing a double-strand chromosome break by homologous recombination: revisiting Robin Holliday's model","volume":"359","author":"Haber","year":"2004","journal-title":"Philos. Trans. R Soc. Lond. B Biol. Sci."},{"key":"key\n\t\t\t\t20170512121855_gks1470-B48","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1186\/1472-6750-1-7","article-title":"Mutant loxP vectors for selectable marker recycle and conditional knock-outs","volume":"1","author":"Arakawa","year":"2001","journal-title":"BMC Biotechnol."},{"key":"key\n\t\t\t\t20170512121855_gks1470-B49","doi-asserted-by":"crossref","first-page":"1858","DOI":"10.1053\/j.gastro.2007.09.003","article-title":"5-Fluorouracil is efficiently removed from DNA by the base excision and mismatch repair systems","volume":"133","author":"Fischer","year":"2007","journal-title":"Gastroenterology"},{"key":"key\n\t\t\t\t20170512121855_gks1470-B50","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1084\/jem.20040355","article-title":"Examination of Msh6- and Msh3-deficient mice in class switching reveals overlapping and distinct roles of MutS homologues in antibody diversification","volume":"200","author":"Li","year":"2004","journal-title":"J. Exp. Med."},{"key":"key\n\t\t\t\t20170512121855_gks1470-B51","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1084\/jem.20040691","article-title":"A role for Msh6 but not Msh3 in somatic hypermutation and class switch recombination","volume":"200","author":"Martomo","year":"2004","journal-title":"J. Exp. Med."},{"key":"key\n\t\t\t\t20170512121855_gks1470-B52","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1084\/jem.191.3.579","article-title":"Somatic hypermutation in MutS homologue (MSH)3-, MSH6-, and MSH3\/MSH6-deficient mice reveals a role for the MSH2-MSH6 heterodimer in modulating the base substitution pattern","volume":"191","author":"Wiesendanger","year":"2000","journal-title":"J. Exp. Med."},{"key":"key\n\t\t\t\t20170512121855_gks1470-B53","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1038\/71643","article-title":"MLH3: a DNA mismatch repair gene associated with mammalian microsatellite instability","volume":"24","author":"Lipkin","year":"2000","journal-title":"Nat. Genet."},{"key":"key\n\t\t\t\t20170512121855_gks1470-B54","first-page":"3721","article-title":"Evidence for a connection between the mismatch repair system and the G2 cell cycle checkpoint","volume":"55","author":"Hawn","year":"1995","journal-title":"Cancer Res."},{"key":"key\n\t\t\t\t20170512121855_gks1470-B55","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1038\/nbt1092","article-title":"Rapid generation of specific antibodies by enhanced homologous recombination","volume":"23","author":"Seo","year":"2005","journal-title":"Nat. Biotechnol."},{"key":"key\n\t\t\t\t20170512121855_gks1470-B56","first-page":"2872","article-title":"Mechanisms of action of 6-thioguanine, 6-mercaptopurine, and 8-azaguanine","volume":"35","author":"Nelson","year":"1975","journal-title":"Cancer Res."},{"key":"key\n\t\t\t\t20170512121855_gks1470-B57","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/0092-8674(91)90581-I","article-title":"Increased ratio of targeted to random integration after transfection of chicken B cell lines","volume":"67","author":"Buerstedde","year":"1991","journal-title":"Cell"},{"key":"key\n\t\t\t\t20170512121855_gks1470-B58","doi-asserted-by":"crossref","first-page":"3238","DOI":"10.1073\/pnas.91.8.3238","article-title":"Mismatch repair proteins MutS and MutL inhibit RecA-catalyzed strand transfer between diverged DNAs","volume":"91","author":"Worth","year":"1994","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"key\n\t\t\t\t20170512121855_gks1470-B59","doi-asserted-by":"crossref","first-page":"1175","DOI":"10.1093\/genetics\/139.3.1175","article-title":"Mismatch correction acts as a barrier to homeologous recombination in Saccharomyces cerevisiae","volume":"139","author":"Selva","year":"1995","journal-title":"Genetics"},{"key":"key\n\t\t\t\t20170512121855_gks1470-B60","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1128\/MCB.18.1.93","article-title":"Gene conversion tracts from double-strand break repair in mammalian cells","volume":"18","author":"Elliott","year":"1998","journal-title":"Mol. Cell. Biol."},{"key":"key\n\t\t\t\t20170512121855_gks1470-B61","doi-asserted-by":"crossref","first-page":"5128","DOI":"10.1073\/pnas.89.11.5128","article-title":"Highly efficient gene targeting in embryonic stem cells through homologous recombination with isogenic DNA constructs","volume":"89","author":"te Riele","year":"1992","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"key\n\t\t\t\t20170512121855_gks1470-B62","doi-asserted-by":"crossref","first-page":"8860","DOI":"10.1073\/pnas.85.23.8860","article-title":"A human 200-kDa protein binds selectively to DNA fragments containing G.T mismatches","volume":"85","author":"Jiricny","year":"1988","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"key\n\t\t\t\t20170512121855_gks1470-B63","doi-asserted-by":"crossref","first-page":"23876","DOI":"10.1016\/S0021-9258(18)35918-0","article-title":"The purification of a human mismatch-binding protein and identification of its associated ATPase and helicase activities","volume":"267","author":"Hughes","year":"1992","journal-title":"J. Biol. Chem."},{"key":"key\n\t\t\t\t20170512121855_gks1470-B64","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1038\/45843","article-title":"The thymine glycosylase MBD4 can bind to the product of deamination at methylated CpG sites","volume":"401","author":"Hendrich","year":"1999","journal-title":"Nature"},{"key":"key\n\t\t\t\t20170512121855_gks1470-B65","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1038\/sj.emboj.7600939","article-title":"SMUG1 is able to excise uracil from immunoglobulin genes: insight into mutation versus repair","volume":"25","author":"Di Noia","year":"2006","journal-title":"EMBO J."},{"key":"key\n\t\t\t\t20170512121855_gks1470-B66","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/S1074-7613(00)80594-4","article-title":"Mismatch repair deficiency interferes with the accumulation of mutations in chronically stimulated B cells and not with the hypermutation process","volume":"9","author":"Frey","year":"1998","journal-title":"Immunity"},{"key":"key\n\t\t\t\t20170512121855_gks1470-B67","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1084\/jem.190.3.323","article-title":"Reduced isotype switching in splenic B cells from mice deficient in mismatch repair enzymes","volume":"190","author":"Schrader","year":"1999","journal-title":"J. Exp. Med."},{"key":"key\n\t\t\t\t20170512121855_gks1470-B68","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1038\/nrm3115","article-title":"Mitotic catastrophe: a mechanism for avoiding genomic instability","volume":"12","author":"Vitale","year":"2011","journal-title":"Nat. Rev. Mol. Cell. Biol."},{"key":"key\n\t\t\t\t20170512121855_gks1470-B69","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/0092-8674(95)90318-6","article-title":"Male mice defective in the DNA mismatch repair gene PMS2 exhibit abnormal chromosome synapsis in meiosis","volume":"82","author":"Baker","year":"1995","journal-title":"Cell"},{"key":"key\n\t\t\t\t20170512121855_gks1470-B70","doi-asserted-by":"crossref","first-page":"1729","DOI":"10.1084\/jem.187.11.1729","article-title":"The role of DNA repair in somatic hypermutation of immunoglobulin genes","volume":"187","author":"Kim","year":"1998","journal-title":"J. Exp. Med."},{"key":"key\n\t\t\t\t20170512121855_gks1470-B71","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1084\/jem.189.3.471","article-title":"Severe attenuation of the B cell immune response in Msh2-deficient mice","volume":"189","author":"Vora","year":"1999","journal-title":"J. Exp. Med."},{"key":"key\n\t\t\t\t20170512121855_gks1470-B72","doi-asserted-by":"crossref","first-page":"3819","DOI":"10.4049\/jimmunol.169.7.3819","article-title":"Bcl-2 rescues the germinal center response but does not alter the V gene somatic hypermutation spectrum in MSH2-deficient mice","volume":"169","author":"Alabyev","year":"2002","journal-title":"J. Immunol."},{"key":"key\n\t\t\t\t20170512121855_gks1470-B73","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1038\/nature03147","article-title":"The BCL6 proto-oncogene suppresses p53 expression in germinal-centre B cells","volume":"432","author":"Phan","year":"2004","journal-title":"Nature"},{"key":"key\n\t\t\t\t20170512121855_gks1470-B74","doi-asserted-by":"crossref","first-page":"1923","DOI":"10.1038\/sj.onc.1204276","article-title":"A role for mismatch repair in control of DNA ploidy following DNA damage","volume":"20","author":"Strathdee","year":"2001","journal-title":"Oncogene"},{"key":"key\n\t\t\t\t20170512121855_gks1470-B75","doi-asserted-by":"crossref","first-page":"7002","DOI":"10.1038\/sj.onc.1203172","article-title":"Disruption of ATM in p53-null cells causes multiple functional abnormalities in cellular response to ionizing radiation","volume":"18","author":"Takao","year":"1999","journal-title":"Oncogene"},{"key":"key\n\t\t\t\t20170512121855_gks1470-B76","doi-asserted-by":"crossref","first-page":"997","DOI":"10.1016\/S1097-2765(03)00099-6","article-title":"A p53-dependent checkpoint pathway prevents rereplication","volume":"11","author":"Vaziri","year":"2003","journal-title":"Mol. Cell"},{"key":"key\n\t\t\t\t20170512121855_gks1470-B77","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1038\/ng1052","article-title":"The mismatch repair system is required for S-phase checkpoint activation","volume":"33","author":"Brown","year":"2003","journal-title":"Nat. Genet."},{"key":"key\n\t\t\t\t20170512121855_gks1470-B78","doi-asserted-by":"crossref","first-page":"1463","DOI":"10.1016\/j.dnarep.2007.04.013","article-title":"Mutations affecting a putative MutLalpha endonuclease motif impact multiple mismatch repair functions","volume":"6","author":"Erdeniz","year":"2007","journal-title":"DNA Repair"},{"key":"key\n\t\t\t\t20170512121855_gks1470-B79","doi-asserted-by":"crossref","first-page":"1546","DOI":"10.1128\/MCB.12.4.1546","article-title":"Formation of heteroduplex DNA during mammalian intrachromosomal gene conversion","volume":"12","author":"Bollag","year":"1992","journal-title":"Mol. Cell. Biol."},{"key":"key\n\t\t\t\t20170512121855_gks1470-B80","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1093\/genetics\/154.1.133","article-title":"Regulation of mitotic homeologous recombination in yeast. Functions of mismatch repair and nucleotide excision repair genes","volume":"154","author":"Nicholson","year":"2000","journal-title":"Genetics"},{"key":"key\n\t\t\t\t20170512121855_gks1470-B81","doi-asserted-by":"crossref","first-page":"10759","DOI":"10.1158\/0008-5472.CAN-05-2528","article-title":"Expression of the MutL homologue hMLH3 in human cells and its role in DNA mismatch repair","volume":"65","author":"Cannavo","year":"2005","journal-title":"Cancer Res."},{"key":"key\n\t\t\t\t20170512121855_gks1470-B82","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1016\/j.molcel.2007.04.018","article-title":"Structure of the human MutSalpha DNA lesion recognition complex","volume":"26","author":"Warren","year":"2007","journal-title":"Mol. Cell"},{"key":"key\n\t\t\t\t20170512121855_gks1470-B83","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1084\/jem.20042066","article-title":"MSH2-MSH6 stimulates DNA polymerase eta, suggesting a role for A:T mutations in antibody genes","volume":"201","author":"Wilson","year":"2005","journal-title":"J. Exp. Med."}],"container-title":["Nucleic Acids Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/nar\/article-pdf\/41\/5\/3032\/16944779\/gks1470.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,5]],"date-time":"2022-02-05T20:09:48Z","timestamp":1644091788000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/nar\/article-lookup\/doi\/10.1093\/nar\/gks1470"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,1,10]]},"references-count":83,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2013,1,10]]},"published-print":{"date-parts":[[2013,3]]}},"URL":"https:\/\/doi.org\/10.1093\/nar\/gks1470","relation":{},"ISSN":["1362-4962","0305-1048"],"issn-type":[{"value":"1362-4962","type":"electronic"},{"value":"0305-1048","type":"print"}],"subject":[],"published":{"date-parts":[[2013,1,10]]}}}