{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T04:16:41Z","timestamp":1790482601905,"version":"4.1.0"},"reference-count":35,"publisher":"Oxford University Press (OUP)","issue":"8","license":[{"start":{"date-parts":[[2016,11,7]],"date-time":"2016-11-07T00:00:00Z","timestamp":1478476800000},"content-version":"vor","delay-in-days":591,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2015,4,30]]},"DOI":"10.1093\/nar\/gkv259","type":"journal-article","created":{"date-parts":[[2015,3,28]],"date-time":"2015-03-28T23:49:44Z","timestamp":1427586584000},"page":"4055-4066","source":"Crossref","is-referenced-by-count":58,"title":["Significance of ligand interactions involving Hop2-Mnd1 and the RAD51 and DMC1 recombinases in homologous DNA repair and XX ovarian dysgenesis"],"prefix":"10.1093","volume":"43","author":[{"given":"Weixing","family":"Zhao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick","family":"Sung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2015,3,27]]},"reference":[{"key":"key\n\t\t\t\t20171011220104_B1","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1146\/annurev.biochem.77.061306.125255","article-title":"Mechanism of eukaryotic homologous recombination","volume":"77","author":"San\u00a0Filippo","year":"2008","journal-title":"Annu. Rev. Biochem."},{"key":"key\n\t\t\t\t20171011220104_B2","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1038\/nrg1614","article-title":"Homologous chromosome interactions in meiosis: diversity amidst conservation","volume":"6","author":"Gerton","year":"2005","journal-title":"Nat. Rev. Genet."},{"key":"key\n\t\t\t\t20171011220104_B3","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1038\/nature04885","article-title":"Clarifying the mechanics by formation of DNA double-strand breaks: mechanism and regulation of DNAstrand exchange in meiotic recombination","volume":"442","author":"Neale","year":"2006","journal-title":"Nature"},{"key":"key\n\t\t\t\t20171011220104_B4","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1016\/0092-8674(92)90446-J","article-title":"DMC1: a meiosis-specific yeast homolog of E. coli recA required for recombination, synaptonemal complex formation, and cell cycle progression","volume":"69","author":"Bishop","year":"1992","journal-title":"Cell"},{"key":"key\n\t\t\t\t20171011220104_B5","doi-asserted-by":"crossref","first-page":"630","DOI":"10.1128\/MMBR.66.4.630-670.2002","article-title":"Role of RAD52 epistasis group genes in homologous recombination and double-strand break repair","volume":"66","author":"Symington","year":"2002","journal-title":"Microbiol. Mol. Biol. Rev."},{"key":"key\n\t\t\t\t20171011220104_B6","doi-asserted-by":"crossref","first-page":"10572","DOI":"10.1073\/pnas.0404195101","article-title":"Heterodimeric complexes of Hop2 and Mnd1 function with Dmc1 to promote meiotic homolog juxtaposition and strand assimilation","volume":"101","author":"Chen","year":"2004","journal-title":"Proc. Natl Acad. Sci. U.S.A."},{"key":"key\n\t\t\t\t20171011220104_B7","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1038\/nsmb923","article-title":"The Hop2 and Mnd1 proteins act in concert with Rad51 and Dmc1 in meiotic recombination","volume":"12","author":"Petukhova","year":"2005","journal-title":"Nat. Struct. Mol. Biol."},{"key":"key\n\t\t\t\t20171011220104_B8","doi-asserted-by":"crossref","first-page":"5575","DOI":"10.1074\/jbc.M506506200","article-title":"Stimulation of DNA strand exchange by the human TBPIP\/Hop2-Mnd1 complex","volume":"281","author":"Enomoto","year":"2006","journal-title":"J. Biol. Chem."},{"key":"key\n\t\t\t\t20171011220104_B9","doi-asserted-by":"crossref","first-page":"2719","DOI":"10.1093\/nar\/gkm174","article-title":"Stimulation of fission yeast and mouse Hop2-Mnd1 of the Dmc1 and Rad51 recombinases","volume":"35","author":"Ploquin","year":"2007","journal-title":"Nucleic Acids Res."},{"key":"key\n\t\t\t\t20171011220104_B10","doi-asserted-by":"crossref","first-page":"4924","DOI":"10.1105\/tpc.113.118521","article-title":"Sufficient amounts of functional HOP2\/MND1 complex promote interhomolog DNA repair but are dispensable for intersister DNA repair during meiosis in Arabidopsis","volume":"25","author":"Uanschou","year":"2013","journal-title":"Plant Cell"},{"key":"key\n\t\t\t\t20171011220104_B11","doi-asserted-by":"crossref","first-page":"1758","DOI":"10.1101\/gad.1562907","article-title":"Hop2\/Mnd1 acts on two critical steps in Dmc1-promoted homologous pairing","volume":"21","author":"Pezza","year":"2007","journal-title":"Genes Dev."},{"key":"key\n\t\t\t\t20171011220104_B12","doi-asserted-by":"crossref","first-page":"906","DOI":"10.1093\/nar\/gkt924","article-title":"Mechanistic insights into the role of Hop2-Mnd1 in meiotic homologous DNA pairing","volume":"42","author":"Zhao","year":"2014","journal-title":"Nucleic Acids Res."},{"key":"key\n\t\t\t\t20171011220104_B13","doi-asserted-by":"crossref","first-page":"1747","DOI":"10.1101\/gad.1563007","article-title":"Bipartite stimulatory action of the Hop2-Mnd1 complex on the Rad51 recombinase","volume":"21","author":"Chi","year":"2007","journal-title":"Genes Dev."},{"key":"key\n\t\t\t\t20171011220104_B14","doi-asserted-by":"crossref","first-page":"4198","DOI":"10.1038\/ncomms5198","article-title":"HOP2-MND1 modulates RAD51 binding to nucleotides and DNA","volume":"5","author":"Bugreev","year":"2014","journal-title":"Nat. Commun."},{"key":"key\n\t\t\t\t20171011220104_B15","doi-asserted-by":"crossref","first-page":"18076","DOI":"10.1074\/jbc.M114.558601","article-title":"The 3rd exon of the budding yeast meiotic recombination gene HOP2 is required for calcium-dependent and recombinase Dmc1-specific stimulation of homologous strand assimilation","volume":"289","author":"Chan","year":"2014","journal-title":"J. Biol. Chem."},{"key":"key\n\t\t\t\t20171011220104_B16","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1016\/j.dnarep.2005.12.007","article-title":"Atmnd1-delta1 is sensitive to gamma-irradiation and defective in meiotic DNA repair","volume":"5","author":"Domenichini","year":"2006","journal-title":"DNA Repair (Amst.)"},{"key":"key\n\t\t\t\t20171011220104_B17","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/j.cell.2014.08.030","article-title":"Interchromosomal homology searches drive directional ALT telomere movement and synapsis","volume":"159","author":"Cho","year":"2014","journal-title":"Cell"},{"key":"key\n\t\t\t\t20171011220104_B18","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1177\/1947601913486344","article-title":"Inactivating mutations in GT198 in familial and early-onset breast and ovarian cancers","volume":"4","author":"Peng","year":"2013","journal-title":"Genes Cancer"},{"key":"key\n\t\t\t\t20171011220104_B19","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1177\/1947601913486345","article-title":"GT198 splice variants display dominant-negative activities and are induced by inactivating mutations","volume":"4","author":"Peng","year":"2013","journal-title":"Genes Cancer"},{"key":"key\n\t\t\t\t20171011220104_B20","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1016\/j.ajhg.2011.09.006","article-title":"XX ovarian dysgenesis is caused by a PSMC3IP\/HOP2 mutation that abolishes coactivation of estrogen-driven transcription","volume":"89","author":"Zangen","year":"2011","journal-title":"Am. J. Hum. Genet."},{"key":"key\n\t\t\t\t20171011220104_B21","doi-asserted-by":"crossref","first-page":"8798","DOI":"10.1074\/jbc.M010011200","article-title":"Basis for avid homologous DNA strand exchange by human Rad51 and RPA","volume":"276","author":"Sigurdsson","year":"2001","journal-title":"J. Biol. Chem."},{"key":"key\n\t\t\t\t20171011220104_B22","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1038\/nature02563","article-title":"Human meiotic recombinase Dmc1 promotes ATP-dependent homologous DNA strand exchange","volume":"429","author":"Sehorn","year":"2004","journal-title":"Nature"},{"key":"key\n\t\t\t\t20171011220104_B23","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1016\/j.dnarep.2005.11.005","article-title":"Roles of ATP binding and ATP hydrolysis in human Rad51 recombinase function","volume":"5","author":"Chi","year":"2006","journal-title":"DNA Repair (Amst.)"},{"key":"key\n\t\t\t\t20171011220104_B24","doi-asserted-by":"crossref","first-page":"9988","DOI":"10.1073\/pnas.0402105101","article-title":"Ca2+ activates human homologous recombination protein Rad51 by modulating its ATPase activity","volume":"101","author":"Bugreev","year":"2004","journal-title":"Proc. Natl Acad. Sci. U.S.A."},{"key":"key\n\t\t\t\t20171011220104_B25","doi-asserted-by":"crossref","first-page":"1494","DOI":"10.1126\/science.1962209","article-title":"Selective cleavage of human DNA: RecA-assisted restriction endonuclease (RARE) cleavage","volume":"254","author":"Ferrin","year":"1991","journal-title":"Science"},{"key":"key\n\t\t\t\t20171011220104_B26","doi-asserted-by":"crossref","first-page":"11932","DOI":"10.1021\/bi9810297","article-title":"Interaction of Rad51 with ATP and Mg2 +induces a conformational change in Rad51","volume":"37","author":"Namsaraev","year":"1998","journal-title":"Biochemistry"},{"key":"key\n\t\t\t\t20171011220104_B27","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1128\/MCB.22.1.357-369.2002","article-title":"Identification and characterization of a tissue-specific coactivator, GT198, that interacts with the DNA-binding domains of nuclear receptors","volume":"22","author":"Ko","year":"2002","journal-title":"Mol. Cell. Biol."},{"key":"key\n\t\t\t\t20171011220104_B28","doi-asserted-by":"crossref","first-page":"752","DOI":"10.1016\/j.cub.2004.04.030","article-title":"Mnd1 is required for meiotic interhomolog repair","volume":"14","author":"Zierhut","year":"2004","journal-title":"Curr. Biol."},{"key":"key\n\t\t\t\t20171011220104_B29","doi-asserted-by":"crossref","first-page":"18426","DOI":"10.1074\/jbc.M601073200","article-title":"Molecular activities of meiosis-specific proteins Hop2, Mnd1, and the Hop2-Mnd1 complex","volume":"281","author":"Pezza","year":"2006","journal-title":"J. Biol. Chem."},{"key":"key\n\t\t\t\t20171011220104_B30","doi-asserted-by":"crossref","first-page":"14682","DOI":"10.1074\/jbc.M114.548180","article-title":"Solution structure and DNA-binding properties of the winged helix domain of the meiotic recombination HOP2 protein","volume":"289","author":"Moktan","year":"2014","journal-title":"J. Biol. Chem."},{"key":"key\n\t\t\t\t20171011220104_B31","doi-asserted-by":"crossref","first-page":"2915","DOI":"10.1038\/sj.emboj.7601739","article-title":"Interactions between human BRCA2 protein and the meiosis-specific recombinase DMC1","volume":"26","author":"Thorslund","year":"2007","journal-title":"EMBO J."},{"key":"key\n\t\t\t\t20171011220104_B32","doi-asserted-by":"crossref","first-page":"3560","DOI":"10.1073\/pnas.1016454108","article-title":"Molecular basis for enhancement of the meiotic DMC1 recombinase by RAD51 associated protein 1 (RAD51AP1)","volume":"108","author":"Dray","year":"2011","journal-title":"Proc. Natl Acad. Sci. U.S.A."},{"key":"key\n\t\t\t\t20171011220104_B33","doi-asserted-by":"crossref","first-page":"37328","DOI":"10.1074\/jbc.M111.290015","article-title":"RAD51-associated protein 1 (RAD51AP1) interacts with the meiotic recombinase DMC1 through a conserved motif","volume":"286","author":"Dunlop","year":"2011","journal-title":"J. Biol. Chem."},{"key":"key\n\t\t\t\t20171011220104_B34","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1016\/S1534-5807(03)00369-1","article-title":"The Hop2 protein has a direct role in promoting interhomolog interactions during mouse meiosis","volume":"5","author":"Petukhova","year":"2003","journal-title":"Dev. Cell"},{"key":"key\n\t\t\t\t20171011220104_B35","doi-asserted-by":"crossref","first-page":"2346","DOI":"10.1093\/nar\/gkt1234","article-title":"The dual role of HOP2 in mammalian meiotic homologous recombination","volume":"42","author":"Pezza","year":"2014","journal-title":"Nucleic Acids Res."}],"container-title":["Nucleic Acids Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/nar\/article-pdf\/43\/8\/4055\/17436739\/gkv259.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,4,2]],"date-time":"2018-04-02T10:42:58Z","timestamp":1522665778000},"score":1,"resource":{"primary":{"URL":"http:\/\/academic.oup.com\/nar\/article\/43\/8\/4055\/2414401\/Significance-of-ligand-interactions-involving"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,3,27]]},"references-count":35,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2015,3,27]]},"published-print":{"date-parts":[[2015,4,30]]}},"URL":"https:\/\/doi.org\/10.1093\/nar\/gkv259","relation":{},"ISSN":["1362-4962","0305-1048"],"issn-type":[{"value":"1362-4962","type":"electronic"},{"value":"0305-1048","type":"print"}],"subject":[],"published-other":{"date-parts":[[2015,4,30]]},"published":{"date-parts":[[2015,3,27]]}}}