{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T04:12:01Z","timestamp":1783743121225,"version":"3.55.0"},"reference-count":84,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2016,11,24]],"date-time":"2016-11-24T00:00:00Z","timestamp":1479945600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2017,4,7]]},"DOI":"10.1093\/nar\/gkw1043","type":"journal-article","created":{"date-parts":[[2016,10,24]],"date-time":"2016-10-24T11:05:23Z","timestamp":1477307123000},"page":"3422-3436","source":"Crossref","is-referenced-by-count":85,"title":["Spliceosomal protein eftud2 mutation leads to p53-dependent apoptosis in zebrafish neural progenitors"],"prefix":"10.1093","volume":"45","author":[{"given":"Lei","family":"Lei","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shou-Yu","family":"Yan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ran","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jia-Yu","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yumei","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ye","family":"Bu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nannan","family":"Chang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qinchao","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaojun","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chuan-Yun","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing-Wei","family":"Xiong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2016,11,24]]},"reference":[{"key":"key\n\t\t\t\t20170508170716_B1","doi-asserted-by":"crossref","first-page":"1147","DOI":"10.1002\/bies.10394","article-title":"The spliceosome: the most complex macromolecular machine in the cell","volume":"25","year":"2003","journal-title":"BioEssays"},{"key":"key\n\t\t\t\t20170508170716_B2","first-page":"a003707","article-title":"Spliceosome structure and function","volume":"3","year":"2011","journal-title":"Cold Spring Harb. Perspect. Biol."},{"key":"key\n\t\t\t\t20170508170716_B3","doi-asserted-by":"crossref","first-page":"612","DOI":"10.1016\/j.bbagrm.2013.02.005","article-title":"Nonsense-mediated mRNA decay\u2014mechanisms of substrate mRNA recognition and degradation in mammalian cells","volume":"1829","year":"2013","journal-title":"Biochim. Biophys. Acta"},{"key":"key\n\t\t\t\t20170508170716_B4","doi-asserted-by":"crossref","first-page":"1333","DOI":"10.1261\/rna.2113605","article-title":"Transcript selection and the recruitment of mRNA decay factors for NMD in saccharomyces cerevisiae","volume":"11","year":"2005","journal-title":"RNA"},{"key":"key\n\t\t\t\t20170508170716_B5","doi-asserted-by":"crossref","first-page":"3726","DOI":"10.1105\/tpc.113.115485","article-title":"Nonsense-mediated decay of alternative precursor mRNA splicing variants is a major determinant of the arabidopsis steady state transcriptome","volume":"25","year":"2013","journal-title":"Plant Cell"},{"key":"key\n\t\t\t\t20170508170716_B6","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1007\/s00018-009-0177-1","article-title":"Nonsense-mediated mRNA decay in human cells: mechanistic insights, functions beyond quality control and the double-life of NMD factors","volume":"67","year":"2010","journal-title":"Cell. Mol. Life Sci."},{"key":"key\n\t\t\t\t20170508170716_B7","doi-asserted-by":"crossref","first-page":"3219","DOI":"10.1128\/MCB.22.10.3219-3229.2002","article-title":"Human U4\/U6.U5 and U4atac\/U6atac.U5 Tri-snRNPs Exhibit Similar Protein Compositions","volume":"22","year":"2002","journal-title":"Mol. Cell. Biol."},{"key":"key\n\t\t\t\t20170508170716_B8","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1016\/S0092-8674(00)81057-0","article-title":"A novel spliceosome containing U11, U12, and U5 snRNPs excises a minor class (AT-AC) intron in vitro","volume":"84","year":"1996","journal-title":"Cell"},{"key":"key\n\t\t\t\t20170508170716_B9","doi-asserted-by":"crossref","first-page":"928","DOI":"10.1042\/BST0320928","article-title":"Roles of the U5 snRNP in spliceosome dynamics and catalysis","volume":"32","year":"2004","journal-title":"Biochem. Soc. Trans."},{"key":"key\n\t\t\t\t20170508170716_B10","doi-asserted-by":"crossref","first-page":"4092","DOI":"10.1093\/emboj\/16.13.4092","article-title":"An evolutionarily conserved U5 snRNP-specific protein is a GTP-binding factor closely related to the ribosomal translocase EF-2","volume":"16","year":"1997","journal-title":"EMBO J"},{"key":"key\n\t\t\t\t20170508170716_B11","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1042\/BST0360551","article-title":"The role of Snu114p during pre-mRNA splicing","volume":"36","year":"2008","journal-title":"Biochem. Soc. Trans."},{"key":"key\n\t\t\t\t20170508170716_B12","doi-asserted-by":"crossref","first-page":"1063","DOI":"10.1534\/genetics.105.042044","article-title":"Genetic analysis reveals a role for the C terminus of the saccharomyces cerevisiae GTPase Snu114 during spliceosome activation","volume":"170","year":"2005","journal-title":"Genetics"},{"key":"key\n\t\t\t\t20170508170716_B13","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1186\/1750-1172-8-110","article-title":"Oto-facial syndrome and esophageal atresia, intellectual disability and zygomatic anomalies - expanding the phenotypes associated with EFTUD2 mutations","volume":"8","year":"2013","journal-title":"Orphanet J. Rare Dis."},{"key":"key\n\t\t\t\t20170508170716_B14","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1111\/cge.12328","article-title":"Array-CGH is an effective first-tier diagnostic test for EFTUD2-associated congenital mandibulofacial dysostosis with microcephaly","volume":"87","year":"2015","journal-title":"Clin. Genet."},{"key":"key\n\t\t\t\t20170508170716_B15","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1136\/jmedgenet-2012-101173","article-title":"EFTUD2 haploinsufficiency leads to syndromic oesophageal atresia","volume":"49","year":"2012","journal-title":"J. Med. Genet."},{"key":"key\n\t\t\t\t20170508170716_B16","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1002\/humu.22517","article-title":"Delineation of EFTUD2 haploinsufficiency-related phenotypes through a series of 36 patients","volume":"35","year":"2014","journal-title":"Hum. Mutat."},{"key":"key\n\t\t\t\t20170508170716_B17","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1016\/j.ajhg.2011.12.023","article-title":"Haploinsufficiency of a spliceosomal GTPase encoded by EFTUD2 causes mandibulofacial dysostosis with microcephaly","volume":"90","year":"2012","journal-title":"Am. J. Hum. Genet."},{"key":"key\n\t\t\t\t20170508170716_B18","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1002\/ajmg.a.35696","article-title":"\u2018Mandibulofacial dysostosis with microcephaly\u2019 caused by EFTUD2 mutations: expanding the phenotype","volume":"161","year":"2013","journal-title":"Am. J. Med. Gene A"},{"key":"key\n\t\t\t\t20170508170716_B19","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1007\/s13353-014-0255-4","article-title":"Phenotype analysis of Polish patients with mandibulofacial dysostosis type guion-almeida associated with esophageal atresia and choanal atresia caused by EFTUD2 gene mutations","volume":"56","year":"2015","journal-title":"J. Appl. Genet."},{"key":"key\n\t\t\t\t20170508170716_B20","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1597\/13-221","article-title":"Radioulnar synostosis and brain abnormalities in a Patient With 17q21.31 microdeletion involving EFTUD2","volume":"52","year":"2015","journal-title":"Cleft Palate Craniofac. J."},{"key":"key\n\t\t\t\t20170508170716_B21","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1523\/JNEUROSCI.11-02-00311.1991","article-title":"Developmental neurobiology of the zebrafish","volume":"11","year":"1991","journal-title":"J. Neurosci."},{"key":"key\n\t\t\t\t20170508170716_B22","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1016\/S0301-0082(03)00052-2","article-title":"From cells to circuits: development of the zebrafish spinal cord","volume":"69","year":"2003","journal-title":"Prog. Neurobiol."},{"key":"key\n\t\t\t\t20170508170716_B23","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1038\/nrm1739","article-title":"The cell biology of neurogenesis","volume":"6","year":"2005","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"key\n\t\t\t\t20170508170716_B24","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/S0736-5748(00)00093-9","article-title":"Neurogenesis in the vertebrate neural tube","volume":"19","year":"2001","journal-title":"Int. J. Dev. Neurosci."},{"key":"key\n\t\t\t\t20170508170716_B25","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.yexcr.2013.10.003","article-title":"Cell fate control in the developing central nervous system","volume":"321","year":"2014","journal-title":"Exp. Cell Res."},{"key":"key\n\t\t\t\t20170508170716_B26","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1002\/1097-0177(2000)9999:9999<::AID-DVDY1052>3.3.CO;2-B","article-title":"Zebrafish neural induction and patterning","volume":"219","year":"2000","journal-title":"Dev. Dyn."},{"key":"key\n\t\t\t\t20170508170716_B27","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1042\/BJ20130176","article-title":"How Sox2 maintains neural stem cell identity","volume":"450","year":"2013","journal-title":"Biochem. J."},{"key":"key\n\t\t\t\t20170508170716_B28","doi-asserted-by":"crossref","first-page":"1162","DOI":"10.1038\/nn1131","article-title":"Vertebrate neurogenesis is counteracted by Sox1-3 activity","volume":"6","year":"2003","journal-title":"Nat. Neurosci."},{"key":"key\n\t\t\t\t20170508170716_B29","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1016\/j.tins.2005.08.008","article-title":"From stem cells to neurons and glia: a Soxist's view of neural development","volume":"28","year":"2005","journal-title":"Trends Neurosci"},{"key":"key\n\t\t\t\t20170508170716_B30","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.abb.2014.05.028","article-title":"Neurogenins in brain development and disease: an overview","volume":"558","year":"2014","journal-title":"Arch. Biochem. Biophys."},{"key":"key\n\t\t\t\t20170508170716_B31","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1186\/1749-8104-8-3","article-title":"Neurogenesis in zebrafish \u2013 from embryo to adult","volume":"8","year":"2013","journal-title":"Neural Dev."},{"key":"key\n\t\t\t\t20170508170716_B32","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1186\/1471-213X-7-89","article-title":"Expression of the zebrafish intermediate neurofilament Nestin in the developing nervous system and in neural proliferation zones at postembryonic stages","volume":"7","year":"2007","journal-title":"BMC Dev. Biol."},{"key":"key\n\t\t\t\t20170508170716_B33","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/S0378-1119(03)00526-2","article-title":"Structural and functional characterization of the zebrafish gene for glial fibrillary acidic protein, GFAP","volume":"310","year":"2003","journal-title":"Gene"},{"key":"key\n\t\t\t\t20170508170716_B34","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1002\/wsbm.1239","article-title":"Neural stem and progenitor cells in health and disease","volume":"5","year":"2013","journal-title":"Wiley Interdiscip. Rev. Syst. Biol. Med."},{"key":"key\n\t\t\t\t20170508170716_B35","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1038\/ng0498-338","article-title":"A microsatellite genetic linkage map for zebrafish (Danio rerio)","volume":"18","year":"1998","journal-title":"Nat. Genet."},{"key":"key\n\t\t\t\t20170508170716_B36","doi-asserted-by":"crossref","first-page":"1007","DOI":"10.1016\/j.modgep.2006.04.006","article-title":"GFAP transgenic zebrafish","volume":"6","year":"2006","journal-title":"Gene Expr. Patterns"},{"key":"key\n\t\t\t\t20170508170716_B37","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/S0925-4773(02)00413-6","article-title":"Multiple regulatory elements with spatially and temporally distinct activities control neurogenin1 expression in primary neurons of the zebrafish embryo","volume":"120","year":"2003","journal-title":"Mech. Dev."},{"key":"key\n\t\t\t\t20170508170716_B38","doi-asserted-by":"crossref","first-page":"3517","DOI":"10.1128\/MCB.00177-09","article-title":"Nonsense-mediated mRNA decay effectors are essential for zebrafish embryonic development and survival","volume":"29","year":"2009","journal-title":"Mol. Cell Biol."},{"key":"key\n\t\t\t\t20170508170716_B39","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1038\/nprot.2007.514","article-title":"High-resolution in situ hybridization to whole-mount zebrafish embryos","volume":"3","year":"2008","journal-title":"Nat. Protoc."},{"key":"key\n\t\t\t\t20170508170716_B40","doi-asserted-by":"crossref","first-page":"2761","DOI":"10.1242\/jcs.145367","article-title":"Protein tyrosine phosphatase PTPN9 regulates erythroid cell development through STAT3 dephosphorylation in zebrafish","volume":"127","year":"2014","journal-title":"J. Cell Sci."},{"key":"key\n\t\t\t\t20170508170716_B41","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1016\/j.molcel.2011.04.018","article-title":"Identification of a microRNA that activates gene expression by repressing nonsense-mediated RNA decay","volume":"42","year":"2011","journal-title":"Mol. Cell"},{"key":"key\n\t\t\t\t20170508170716_B42","first-page":"368","article-title":"Systemic splicing factor deficiency causes tissue-specific defects: a zebrafish model for retinitis pigmentosa","volume":"20","year":"2010","journal-title":"Hum. Mol. Genet."},{"key":"key\n\t\t\t\t20170508170716_B43","doi-asserted-by":"crossref","first-page":"e123","DOI":"10.1093\/nar\/gkp596","article-title":"Transcriptome analysis by strand-specific sequencing of complementary DNA","volume":"37","year":"2009","journal-title":"Nucleic Acids Res."},{"key":"key\n\t\t\t\t20170508170716_B44","doi-asserted-by":"crossref","first-page":"1309","DOI":"10.1093\/molbev\/msu084","article-title":"Evolutionary interrogation of human biology in well-annotated genomic framework of rhesus macaque","volume":"31","year":"2014","journal-title":"Mol. Biol. Evol."},{"key":"key\n\t\t\t\t20170508170716_B45","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1038\/nature07509","article-title":"Alternative isoform regulation in human tissue transcriptomes","volume":"456","year":"2008","journal-title":"Nature"},{"key":"key\n\t\t\t\t20170508170716_B46","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1016\/j.cell.2013.06.052","article-title":"Orchestrated intron retention regulates normal granulocyte differentiation","volume":"154","year":"2013","journal-title":"Cell"},{"key":"key\n\t\t\t\t20170508170716_B47","doi-asserted-by":"crossref","first-page":"986","DOI":"10.1101\/gr.7.10.986","article-title":"The significance of digital gene expression profiles","volume":"7","year":"1997","journal-title":"Genome Res."},{"key":"key\n\t\t\t\t20170508170716_B48","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1089\/1066527041410418","article-title":"Maximum entropy modeling of short sequence motifs with applications to RNA splicing signals","volume":"11","year":"2004","journal-title":"J. Comput. Biol."},{"key":"key\n\t\t\t\t20170508170716_B49","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1186\/s12915-014-0055-7","article-title":"Simultaneous high-resolution detection of multiple transcripts combined with localization of proteins in whole-mount embryos","volume":"12","year":"2014","journal-title":"BMC Biol."},{"key":"key\n\t\t\t\t20170508170716_B50","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1093\/bioinformatics\/btp612","article-title":"DEGseq: an R package for identifying differentially expressed genes from RNA-seq data","volume":"26","year":"2010","journal-title":"Bioinformatics"},{"key":"key\n\t\t\t\t20170508170716_B51","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1038\/nature08869","article-title":"Phenotypic profiling of the human genome by time-lapse microscopy reveals cell division genes","volume":"464","year":"2010","journal-title":"Nature"},{"key":"key\n\t\t\t\t20170508170716_B52","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1093\/hmg\/ddp534","article-title":"Gain and loss of function of ALS-related mutations of TARDBP (TDP-43) cause motor deficits in vivo","volume":"19","year":"2010","journal-title":"Hum. Mol. Genet."},{"key":"key\n\t\t\t\t20170508170716_B53","doi-asserted-by":"crossref","first-page":"1432","DOI":"10.1261\/rna.038893.113","article-title":"Comparison of EJC-enhanced and EJC-independent NMD in human cells reveals two partially redundant degradation pathways","volume":"19","year":"2013","journal-title":"RNA"},{"key":"key\n\t\t\t\t20170508170716_B54","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1038\/nsmb.1550","article-title":"Nonsense-mediated mRNA decay (NMD) mechanisms","volume":"16","year":"2009","journal-title":"Nat. Struct. Mol. Biol."},{"key":"key\n\t\t\t\t20170508170716_B55","doi-asserted-by":"crossref","first-page":"1209","DOI":"10.1101\/gad.188037.112","article-title":"Coordinated regulation of neuronal mRNA steady-state levels through developmentally controlled intron retention","volume":"26","year":"2012","journal-title":"Genes Dev."},{"key":"key\n\t\t\t\t20170508170716_B56","doi-asserted-by":"crossref","first-page":"1774","DOI":"10.1101\/gr.177790.114","article-title":"Widespread intron retention in mammals functionally tunes transcriptomes","volume":"24","year":"2014","journal-title":"Genome Res."},{"key":"key\n\t\t\t\t20170508170716_B57","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1101\/gad.247361.114","article-title":"Detained introns are a novel, widespread class of post-transcriptionally spliced introns","volume":"29","year":"2015","journal-title":"Genes Dev."},{"key":"key\n\t\t\t\t20170508170716_B58","doi-asserted-by":"crossref","first-page":"8319","DOI":"10.1093\/nar\/gkt585","article-title":"DHX34 and NBAS form part of an autoregulatory NMD circuit that regulates endogenous RNA targets in human cells, zebrafish and Caenorhabditis elegans","volume":"41","year":"2013","journal-title":"Nucleic Acids Res."},{"key":"key\n\t\t\t\t20170508170716_B59","doi-asserted-by":"crossref","first-page":"2128","DOI":"10.1128\/MCB.00174-13","article-title":"Inhibition of nonsense-mediated RNA decay activates autophagy","volume":"33","year":"2013","journal-title":"Mol. Cell Biol."},{"key":"key\n\t\t\t\t20170508170716_B60","doi-asserted-by":"crossref","first-page":"3686","DOI":"10.1093\/nar\/gkq1319","article-title":"Dhx34 and Nbas function in the NMD pathway and are required for embryonic development in zebrafish","volume":"39","year":"2011","journal-title":"Nucleic Acids Res."},{"key":"key\n\t\t\t\t20170508170716_B61","doi-asserted-by":"crossref","first-page":"630","DOI":"10.1002\/bdra.23397","article-title":"EFTUD2 deficiency in vertebrates: identification of a novel human mutation and generation of a zebrafish model","volume":"103","year":"2015","journal-title":"Birth Defects Res. A Clin. Mol. Teratol."},{"key":"key\n\t\t\t\t20170508170716_B62","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1038\/nrg2164","article-title":"Splicing in disease: disruption of the splicing code and the decoding machinery","volume":"8","year":"2007","journal-title":"Nat. Rev. Genet."},{"key":"key\n\t\t\t\t20170508170716_B63","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1002\/path.2649","article-title":"The pathobiology of splicing","volume":"220","year":"2010","journal-title":"J. Pathol."},{"key":"key\n\t\t\t\t20170508170716_B64","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/j.tig.2012.01.001","article-title":"New connections between splicing and human disease","volume":"28","year":"2012","journal-title":"Trends Genet."},{"key":"key\n\t\t\t\t20170508170716_B65","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1097\/01.mcd.0000220603.09661.7e","article-title":"A new syndrome with growth and mental retardation, mandibulofacial dysostosis, microcephaly, and cleft palate","volume":"15","year":"2006","journal-title":"Clin. Dysmorphol."},{"key":"key\n\t\t\t\t20170508170716_B66","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1136\/jmedgenet-2012-100819","article-title":"Clinical application of exome sequencing in undiagnosed genetic conditions","volume":"49","year":"2012","journal-title":"J. Med. Genet."},{"key":"key\n\t\t\t\t20170508170716_B67","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/S0736-5748(00)00093-9","article-title":"Neurogenesis in the vertebrate neural tube","volume":"19","year":"2001","journal-title":"Int. J. Dev. Neurosci."},{"key":"key\n\t\t\t\t20170508170716_B68","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1042\/BJ20130176","article-title":"How Sox2 maintains neural stem cell identity","volume":"450","year":"2013","journal-title":"Biochem. J."},{"key":"key\n\t\t\t\t20170508170716_B69","doi-asserted-by":"crossref","first-page":"828","DOI":"10.1016\/j.bbrc.2005.03.194","article-title":"Maintaining appearances\u2014The role of p53 in adult neurogenesis","volume":"331","year":"2005","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"key\n\t\t\t\t20170508170716_B70","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1242\/dev.128.1.137","article-title":"DNA damage-induced neural precursor cell apoptosis requires p53 and caspase 9 but neither Bax nor caspase 3","volume":"128","year":"2001","journal-title":"Development"},{"key":"key\n\t\t\t\t20170508170716_B71","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1016\/j.nbd.2004.09.015","article-title":"Ethylnitrosourea induces neural progenitor cell apoptosis after S-phase accumulation in a p53-dependent manner","volume":"18","year":"2005","journal-title":"Neurobiol. Dis."},{"key":"key\n\t\t\t\t20170508170716_B72","doi-asserted-by":"crossref","first-page":"8497","DOI":"10.1038\/sj.onc.1207821","article-title":"Involvement of p53 and Fas\/CD95 in murine neural progenitor cell response to ionizing irradiation","volume":"23","year":"2004","journal-title":"Oncogene"},{"key":"key\n\t\t\t\t20170508170716_B73","doi-asserted-by":"crossref","first-page":"6608","DOI":"10.1073\/pnas.0701919104","article-title":"Network of coregulated spliceosome components revealed by zebrafish mutant in recycling factor p110","volume":"104","year":"2007","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"key\n\t\t\t\t20170508170716_B74","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1093\/hmg\/ddm300","article-title":"Mutation in the splicing factor Hprp3p linked to retinitis pigmentosa impairs interactions within the U4\/U6 snRNP complex","volume":"17","year":"2007","journal-title":"Hum. Mol. Genet."},{"key":"key\n\t\t\t\t20170508170716_B75","doi-asserted-by":"crossref","first-page":"3173","DOI":"10.1128\/MCB.01807-08","article-title":"PLRG1 is an essential regulator of cell proliferation and apoptosis during vertebrate development and tissue homeostasis","volume":"29","year":"2009","journal-title":"Mol. Cell. Biol."},{"key":"key\n\t\t\t\t20170508170716_B76","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1016\/j.ajhg.2011.04.008","article-title":"A missense mutation in PRPF6 causes impairment of pre-mRNA splicing and autosomal-dominant retinitis pigmentosa","volume":"88","year":"2011","journal-title":"Am. J. Hum. Genet."},{"key":"key\n\t\t\t\t20170508170716_B77","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1016\/j.cell.2011.11.057","article-title":"Mutation of a U2 snRNA gene causes global disruption of alternative splicing and neurodegeneration","volume":"148","year":"2012","journal-title":"Cell"},{"key":"key\n\t\t\t\t20170508170716_B78","doi-asserted-by":"crossref","first-page":"2150","DOI":"10.1016\/j.febslet.2013.05.030","article-title":"In vivo mutation of pre-mRNA processing factor 8 (Prpf8) affects transcript splicing, cell survival and myeloid differentiation","volume":"587","year":"2013","journal-title":"FEBS Lett."},{"key":"key\n\t\t\t\t20170508170716_B79","doi-asserted-by":"crossref","first-page":"3062","DOI":"10.1073\/pnas.1305536111","article-title":"Minor class splicing shapes the zebrafish transcriptome during development","volume":"111","year":"2014","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"key\n\t\t\t\t20170508170716_B80","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/j.molcel.2011.03.014","article-title":"SON controls cell-cycle progression by coordinated regulation of RNA splicing","volume":"42","year":"2011","journal-title":"Mol. Cell"},{"key":"key\n\t\t\t\t20170508170716_B81","doi-asserted-by":"crossref","first-page":"e01201","DOI":"10.7554\/eLife.01201","article-title":"The splicing regulator PTBP2 controls a program of embryonic splicing required for neuronal maturation","volume":"3","year":"2014","journal-title":"Elife"},{"key":"key\n\t\t\t\t20170508170716_B82","doi-asserted-by":"crossref","first-page":"1252","DOI":"10.1016\/j.cell.2013.02.034","article-title":"Dynamic integration of splicing within gene regulatory pathways","volume":"152","year":"2013","journal-title":"Cell"},{"key":"key\n\t\t\t\t20170508170716_B83","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1016\/j.molcel.2010.11.005","article-title":"Splicing-dependent RNA polymerase pausing in yeast","volume":"40","year":"2010","journal-title":"Mol. Cell"},{"key":"key\n\t\t\t\t20170508170716_B84","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1016\/j.celrep.2014.01.028","article-title":"Posttranscriptional control of the stem cell and neurogenic programs by the nonsense-mediated rna decay pathway","volume":"6","year":"2014","journal-title":"Cell Rep."}],"container-title":["Nucleic Acids Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/nar\/article-pdf\/45\/6\/3422\/16663833\/gkw1043.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,7,11]],"date-time":"2022-07-11T02:41:56Z","timestamp":1657507316000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/nar\/article-lookup\/doi\/10.1093\/nar\/gkw1043"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,11,24]]},"references-count":84,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2016,11,24]]},"published-print":{"date-parts":[[2017,4,7]]}},"URL":"https:\/\/doi.org\/10.1093\/nar\/gkw1043","relation":{},"ISSN":["0305-1048","1362-4962"],"issn-type":[{"value":"0305-1048","type":"print"},{"value":"1362-4962","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,11,24]]}}}