{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T14:53:52Z","timestamp":1778770432805,"version":"3.51.4"},"reference-count":69,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2018,12,21]],"date-time":"2018-12-21T00:00:00Z","timestamp":1545350400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"Netherlands organization for Scientific Research","award":["VIDI 700.10.421"],"award-info":[{"award-number":["VIDI 700.10.421"]}]},{"DOI":"10.13039\/501100004622","name":"Dutch Cancer Society","doi-asserted-by":"publisher","award":["KWF HUBR 2015-7736"],"award-info":[{"award-number":["KWF HUBR 2015-7736"]}],"id":[{"id":"10.13039\/501100004622","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,3,18]]},"DOI":"10.1093\/nar\/gky1276","type":"journal-article","created":{"date-parts":[[2018,12,13]],"date-time":"2018-12-13T17:57:59Z","timestamp":1544723879000},"page":"2377-2388","source":"Crossref","is-referenced-by-count":30,"title":["The role of SLX4 and its associated nucleases in DNA interstrand crosslink repair"],"prefix":"10.1093","volume":"47","author":[{"given":"Wouter S","family":"Hoogenboom","sequence":"first","affiliation":[{"name":"Oncode Institute, Hubrecht Institute\u2013KNAW and University Medical Center Utrecht, Utrecht, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rick A C M","family":"Boonen","sequence":"additional","affiliation":[{"name":"Oncode Institute, Hubrecht Institute\u2013KNAW and University Medical Center Utrecht, Utrecht, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Puck","family":"Knipscheer","sequence":"additional","affiliation":[{"name":"Oncode Institute, Hubrecht Institute\u2013KNAW and University Medical Center Utrecht, Utrecht, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2018,12,21]]},"reference":[{"key":"key\n\t\t\t\t2019031201360833100_B1","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1038\/nrc3088","article-title":"DNA interstrand crosslink repair and cancer","volume":"11","author":"Deans","year":"2011","journal-title":"Nat. Rev. Cancer"},{"key":"key\n\t\t\t\t2019031201360833100_B2","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.mrfmmm.2011.03.006","article-title":"DNA damage induced by endogenous aldehydes: Current state of knowledge","volume":"711","author":"Voulgaridou","year":"2011","journal-title":"Mutat. Res."},{"key":"key\n\t\t\t\t2019031201360833100_B3","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1016\/j.cell.2008.08.030","article-title":"Mechanism of replication-coupled DNA interstrand crosslink repair","volume":"134","author":"Raschle","year":"2008","journal-title":"Cell"},{"key":"key\n\t\t\t\t2019031201360833100_B4","doi-asserted-by":"crossref","first-page":"8283","DOI":"10.1128\/MCB.20.21.8283-8289.2000","article-title":"DNA replication is required To elicit cellular responses to psoralen-induced DNA interstrand cross-links","volume":"20","author":"Akkari","year":"2000","journal-title":"Mol. Cell. Biol."},{"key":"key\n\t\t\t\t2019031201360833100_B5","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1016\/j.tibs.2013.05.004","article-title":"The differences between ICL repair during and outside of S phase","volume":"38","author":"Williams","year":"2013","journal-title":"Trends Biochem. Sci."},{"key":"key\n\t\t\t\t2019031201360833100_B6","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1038\/nature11863","article-title":"Fanconi anaemia and the repair of Watson and Crick DNA crosslinks","volume":"493","author":"Kottemann","year":"2013","journal-title":"Nature"},{"key":"key\n\t\t\t\t2019031201360833100_B7","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1146\/annurev-biophys-051013-022737","article-title":"The Fanconi anemia DNA repair pathway: structural and functional insights into a complex disorder","volume":"43","author":"Walden","year":"2014","journal-title":"Annu. Rev. Biophys."},{"key":"key\n\t\t\t\t2019031201360833100_B8","doi-asserted-by":"crossref","first-page":"1698","DOI":"10.1126\/science.1182372","article-title":"The Fanconi anemia pathway promotes replication-dependent DNA interstrand cross-link repair","volume":"326","author":"Knipscheer","year":"2009","journal-title":"Science"},{"key":"key\n\t\t\t\t2019031201360833100_B9","doi-asserted-by":"crossref","first-page":"11117","DOI":"10.1158\/0008-5472.CAN-07-3028","article-title":"Cells deficient in the FANC\/BRCA pathway are hypersensitive to plasma levels of formaldehyde","volume":"67","author":"Ridpath","year":"2007","journal-title":"Cancer Res."},{"key":"key\n\t\t\t\t2019031201360833100_B10","doi-asserted-by":"crossref","first-page":"3206","DOI":"10.1182\/blood-2013-06-507962","article-title":"Variant ALDH2 is associated with accelerated progression of bone marrow failure in Japanese Fanconi anemia patients","volume":"122","author":"Hira","year":"2013","journal-title":"Blood"},{"key":"key\n\t\t\t\t2019031201360833100_B11","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1038\/nature11368","article-title":"Genotoxic consequences of endogenous aldehydes on mouse haematopoietic stem cell function","volume":"489","author":"Garaycoechea","year":"2012","journal-title":"Nature"},{"key":"key\n\t\t\t\t2019031201360833100_B12","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1038\/nature10192","article-title":"Fancd2 counteracts the toxic effects of naturally produced aldehydes in mice","volume":"475","author":"Langevin","year":"2011","journal-title":"Nature"},{"key":"key\n\t\t\t\t2019031201360833100_B13","doi-asserted-by":"crossref","first-page":"1432","DOI":"10.1038\/nsmb.2173","article-title":"Formaldehyde catabolism is essential in cells deficient for the Fanconi anemia DNA-repair pathway","volume":"18","author":"Rosado","year":"2011","journal-title":"Nat. Struct. Mol. Biol."},{"key":"key\n\t\t\t\t2019031201360833100_B14","doi-asserted-by":"crossref","first-page":"1149","DOI":"10.1021\/tx000118t","article-title":"Identification of DNA adducts of acetaldehyde","volume":"13","author":"Wang","year":"2000","journal-title":"Chem. Res. Toxicol."},{"key":"key\n\t\t\t\t2019031201360833100_B15","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1021\/tx025614r","article-title":"Reactions of formaldehyde plus acetaldehyde with deoxyguanosine and DNA: formation of cyclic deoxyguanosine adducts and formaldehyde cross-links","volume":"16","author":"Cheng","year":"2003","journal-title":"Chem. Res. Toxicol."},{"key":"key\n\t\t\t\t2019031201360833100_B16","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1126\/science.1204258","article-title":"Mechanism of RAD51-dependent DNA interstrand cross-link repair","volume":"333","author":"Long","year":"2011","journal-title":"Science"},{"key":"key\n\t\t\t\t2019031201360833100_B17","doi-asserted-by":"crossref","first-page":"1971","DOI":"10.15252\/embj.201490878","article-title":"Regulation of the Rev1-pol zeta complex during bypass of a DNA interstrand cross-link","volume":"34","author":"Budzowska","year":"2015","journal-title":"EMBO J."},{"key":"key\n\t\t\t\t2019031201360833100_B18","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1038\/nsmb.2956","article-title":"DNA interstrand cross-link repair requires replication-fork convergence","volume":"22","author":"Zhang","year":"2015","journal-title":"Nat. Struct. Mol. Biol."},{"key":"key\n\t\t\t\t2019031201360833100_B19","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1016\/j.molcel.2014.03.015","article-title":"XPF-ERCC1 acts in Unhooking DNA interstrand crosslinks in cooperation with FANCD2 and FANCP\/SLX4","volume":"54","author":"Klein\u00a0Douwel","year":"2014","journal-title":"Mol. Cell"},{"key":"key\n\t\t\t\t2019031201360833100_B20","doi-asserted-by":"crossref","first-page":"3419","DOI":"10.1016\/j.celrep.2018.05.061","article-title":"Replication fork reversal during DNA interstrand crosslink repair requires CMG unloading","volume":"23","author":"Amunugama","year":"2018","journal-title":"Cell Rep."},{"key":"key\n\t\t\t\t2019031201360833100_B21","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1016\/j.molcel.2013.09.021","article-title":"The DNA translocase FANCM\/MHF promotes replication traverse of DNA interstrand crosslinks","volume":"52","author":"Huang","year":"2013","journal-title":"Mol. Cell"},{"key":"key\n\t\t\t\t2019031201360833100_B22","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1016\/j.cell.2016.09.008","article-title":"Replication-Dependent unhooking of DNA interstrand Cross-Links by the NEIL3 glycosylase","volume":"167","author":"Semlow","year":"2016","journal-title":"Cell"},{"key":"key\n\t\t\t\t2019031201360833100_B23","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1016\/j.molcel.2014.03.014","article-title":"Mouse SLX4 is a tumor suppressor that stimulates the activity of the nuclease XPF-ERCC1 in DNA crosslink repair","volume":"54","author":"Hodskinson","year":"2014","journal-title":"Mol. Cell"},{"key":"key\n\t\t\t\t2019031201360833100_B24","doi-asserted-by":"crossref","first-page":"569","DOI":"10.14348\/molcells.2014.0118","article-title":"Nuclease delivery: versatile functions of SLX4\/FANCP in genome maintenance","volume":"37","author":"Kim","year":"2014","journal-title":"Mol. Cells"},{"key":"key\n\t\t\t\t2019031201360833100_B25","doi-asserted-by":"crossref","first-page":"848","DOI":"10.1016\/j.molcel.2017.01.031","article-title":"The SMX DNA repair Tri-nuclease","volume":"65","author":"Wyatt","year":"2017","journal-title":"Mol. Cell"},{"key":"key\n\t\t\t\t2019031201360833100_B26","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1101\/sqb.2015.80.027649","article-title":"Resolution of recombination Intermediates: Mechanisms and regulation","volume":"80","author":"West","year":"2015","journal-title":"Cold Spring Harb. Symp. Quant. Biol."},{"key":"key\n\t\t\t\t2019031201360833100_B27","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1101\/sqb.2017.82.034256","article-title":"Genome instability as a consequence of defects in the resolution of recombination intermediates","volume":"82","author":"West","year":"2017","journal-title":"Cold Spring Harb. Symp. Quant. Biol."},{"key":"key\n\t\t\t\t2019031201360833100_B28","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/j.molcel.2014.11.014","article-title":"The SLX4 complex is a SUMO E3 ligase that impacts on replication stress outcome and genome stability","volume":"57","author":"Guervilly","year":"2015","journal-title":"Mol. Cell"},{"key":"key\n\t\t\t\t2019031201360833100_B29","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1182\/blood-2012-07-441212","article-title":"Regulation of multiple DNA repair pathways by the Fanconi anemia protein SLX4","volume":"121","author":"Kim","year":"2013","journal-title":"Blood"},{"key":"key\n\t\t\t\t2019031201360833100_B30","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/j.molcel.2013.08.036","article-title":"Cooperative control of holliday junction resolution and DNA repair by the SLX1 and MUS81-EME1 nucleases","volume":"52","author":"Castor","year":"2013","journal-title":"Mol. Cell"},{"key":"key\n\t\t\t\t2019031201360833100_B31","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.cell.2009.06.030","article-title":"Mammalian BTBD12\/SLX4 assembles a Holliday junction resolvase and is required for DNA repair","volume":"138","author":"Svendsen","year":"2009","journal-title":"Cell"},{"key":"key\n\t\t\t\t2019031201360833100_B32","doi-asserted-by":"crossref","first-page":"4871","DOI":"10.1093\/nar\/gkw354","article-title":"Dimerization of SLX4 contributes to functioning of the SLX4-nuclease complex","volume":"44","author":"Yin","year":"2016","journal-title":"Nucleic Acids Res."},{"key":"key\n\t\t\t\t2019031201360833100_B33","doi-asserted-by":"crossref","first-page":"1604","DOI":"10.1101\/gad.240515.114","article-title":"A cell cycle-regulated Slx4-Dpb11 complex promotes the resolution of DNA repair intermediates linked to stalled replication","volume":"28","author":"Gritenaite","year":"2014","journal-title":"Genes Dev."},{"key":"key\n\t\t\t\t2019031201360833100_B34","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1016\/j.molcel.2013.08.035","article-title":"Coordinated actions of SLX1-SLX4 and MUS81-EME1 for Holliday junction resolution in human cells","volume":"52","author":"Wyatt","year":"2013","journal-title":"Mol. Cell"},{"key":"key\n\t\t\t\t2019031201360833100_B35","doi-asserted-by":"crossref","first-page":"740","DOI":"10.1016\/j.devcel.2016.11.017","article-title":"A mechanism for controlled breakage of Under-replicated chromosomes during mitosis","volume":"39","author":"Duda","year":"2016","journal-title":"Dev. Cell"},{"key":"key\n\t\t\t\t2019031201360833100_B36","doi-asserted-by":"crossref","first-page":"2811","DOI":"10.1242\/jcs.146167","article-title":"Distinct functional roles for the two SLX4 ubiquitin-binding UBZ domains mutated in Fanconi anemia","volume":"127","author":"Lachaud","year":"2014","journal-title":"J. Cell Sci."},{"key":"key\n\t\t\t\t2019031201360833100_B37","doi-asserted-by":"crossref","first-page":"512","DOI":"10.15252\/embr.201440017","article-title":"SUMOylation and PARylation cooperate to recruit and stabilize SLX4 at DNA damage sites","volume":"16","author":"Gonzalez-Prieto","year":"2015","journal-title":"EMBO Rep."},{"key":"key\n\t\t\t\t2019031201360833100_B38","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/j.molcel.2014.11.015","article-title":"Noncovalent interactions with SUMO and ubiquitin orchestrate distinct functions of the SLX4 complex in genome maintenance","volume":"57","author":"Ouyang","year":"2015","journal-title":"Mol. Cell"},{"key":"key\n\t\t\t\t2019031201360833100_B39","doi-asserted-by":"crossref","first-page":"2034","DOI":"10.15252\/embj.201695223","article-title":"Recruitment and positioning determine the specific role of the XPF-ERCC1 endonuclease in interstrand crosslink repair","volume":"36","author":"Klein\u00a0Douwel","year":"2017","journal-title":"EMBO J."},{"key":"key\n\t\t\t\t2019031201360833100_B40","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1016\/j.molcel.2009.06.019","article-title":"Drosophila MUS312 and the vertebrate ortholog BTBD12 interact with DNA structure-specific endonucleases in DNA repair and recombination","volume":"35","author":"Andersen","year":"2009","journal-title":"Mol. Cell"},{"key":"key\n\t\t\t\t2019031201360833100_B41","doi-asserted-by":"crossref","first-page":"1503","DOI":"10.1016\/S1097-2765(02)00782-7","article-title":"Drosophila MUS312 interacts with the nucleotide excision repair endonuclease MEI-9 to generate meiotic crossovers","volume":"10","author":"Yildiz","year":"2002","journal-title":"Mol. Cell"},{"key":"key\n\t\t\t\t2019031201360833100_B42","doi-asserted-by":"crossref","first-page":"26632","DOI":"10.1074\/jbc.C000337200","article-title":"Repair of an interstrand DNA cross-link initiated by ERCC1-XPF repair\/recombination nuclease","volume":"275","author":"Kuraoka","year":"2000","journal-title":"J. Biol. Chem."},{"key":"key\n\t\t\t\t2019031201360833100_B43","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1002\/path.3002","article-title":"The Fanconi anaemia pathway orchestrates incisions at sites of crosslinked DNA","volume":"226","author":"Crossan","year":"2012","journal-title":"J. Pathol."},{"key":"key\n\t\t\t\t2019031201360833100_B44","doi-asserted-by":"crossref","first-page":"1757","DOI":"10.4161\/cc.10.11.15818","article-title":"FANCP\/SLX4: a Swiss army knife of DNA interstrand crosslink repair","volume":"10","author":"Cybulski","year":"2011","journal-title":"Cell Cycle"},{"key":"key\n\t\t\t\t2019031201360833100_B45","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/j.dnarep.2014.03.018","article-title":"Mechanism and regulation of incisions during DNA interstrand cross-link repair","volume":"19","author":"Zhang","year":"2014","journal-title":"DNA Repair (Amst.)"},{"key":"key\n\t\t\t\t2019031201360833100_B46","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/j.molcel.2009.06.020","article-title":"Coordination of structure-specific nucleases by human SLX4\/BTBD12 is required for DNA repair","volume":"35","author":"Munoz","year":"2009","journal-title":"Mol. Cell"},{"key":"key\n\t\t\t\t2019031201360833100_B47","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1016\/j.cell.2011.07.045","article-title":"Selective bypass of a lagging strand roadblock by the eukaryotic replicative DNA helicase","volume":"146","author":"Fu","year":"2011","journal-title":"Cell"},{"key":"key\n\t\t\t\t2019031201360833100_B48","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1016\/j.ydbio.2017.03.033","article-title":"Xenopus egg extract: A powerful tool to study genome maintenance mechanisms","volume":"428","author":"Hoogenboom","year":"2017","journal-title":"Dev. Biol."},{"key":"key\n\t\t\t\t2019031201360833100_B49","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1016\/S1097-2765(00)80052-0","article-title":"Regulated chromosomal DNA replication in the absence of a nucleus","volume":"1","author":"Walter","year":"1998","journal-title":"Mol. Cell"},{"key":"key\n\t\t\t\t2019031201360833100_B50","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1007\/978-1-59745-000-3_9","article-title":"Chromosomal DNA replication in a soluble cell-free system derived from Xenopus eggs","volume":"322","author":"Tutter","year":"2006","journal-title":"Methods Mol. Biol."},{"key":"key\n\t\t\t\t2019031201360833100_B51","doi-asserted-by":"crossref","first-page":"8953","DOI":"10.1093\/nar\/gks670","article-title":"Repair of cisplatin-induced DNA interstrand crosslinks by a replication-independent pathway involving transcription-coupled repair and translesion synthesis","volume":"40","author":"Enoiu","year":"2012","journal-title":"Nucleic Acids Res."},{"key":"key\n\t\t\t\t2019031201360833100_B52","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1007\/978-1-61779-998-3_16","article-title":"Replication-coupled DNA interstrand cross-link repair in Xenopus egg extracts","volume":"920","author":"Knipscheer","year":"2012","journal-title":"Methods Mol. Biol."},{"key":"key\n\t\t\t\t2019031201360833100_B53","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1016\/j.molcel.2006.01.030","article-title":"Localization of MCM2-7, Cdc45, and GINS to the site of DNA unwinding during eukaryotic DNA replication","volume":"21","author":"Pacek","year":"2006","journal-title":"Mol. Cell"},{"key":"key\n\t\t\t\t2019031201360833100_B54","doi-asserted-by":"crossref","first-page":"1467","DOI":"10.1016\/j.celrep.2015.02.019","article-title":"Structural and mechanistic analysis of the Slx1-Slx4 endonuclease","volume":"10","author":"Gaur","year":"2015","journal-title":"Cell Rep."},{"key":"key\n\t\t\t\t2019031201360833100_B55","doi-asserted-by":"crossref","first-page":"a023192","DOI":"10.1101\/cshperspect.a023192","article-title":"Holliday junction resolvases","volume":"6","author":"Wyatt","year":"2014","journal-title":"Cold Spring Harb. Perspect. Biol."},{"key":"key\n\t\t\t\t2019031201360833100_B56","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1016\/j.celrep.2013.07.033","article-title":"Localization-dependent and -independent roles of SLX4 in regulating telomeres","volume":"4","author":"Wilson","year":"2013","journal-title":"Cell Rep."},{"key":"key\n\t\t\t\t2019031201360833100_B57","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1016\/j.cell.2009.06.029","article-title":"Human SLX4 is a Holliday junction resolvase subunit that binds multiple DNA repair\/recombination endonucleases","volume":"138","author":"Fekairi","year":"2009","journal-title":"Cell"},{"key":"key\n\t\t\t\t2019031201360833100_B58","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1038\/ng.752","article-title":"Disruption of mouse Slx4, a regulator of structure-specific nucleases, phenocopies Fanconi anemia","volume":"43","author":"Crossan","year":"2011","journal-title":"Nat. Genet."},{"key":"key\n\t\t\t\t2019031201360833100_B59","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.dnarep.2015.09.022","article-title":"Physical interaction between SLX4 (FANCP) and XPF (FANCQ) proteins and biological consequences of interaction-defective missense mutations","volume":"35","author":"Hashimoto","year":"2015","journal-title":"DNA Repair (Amst.)"},{"key":"key\n\t\t\t\t2019031201360833100_B60","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1016\/j.molcel.2014.08.012","article-title":"BRCA1 promotes unloading of the CMG helicase from a stalled DNA replication fork","volume":"56","author":"Long","year":"2014","journal-title":"Mol. Cell"},{"key":"key\n\t\t\t\t2019031201360833100_B61","doi-asserted-by":"crossref","first-page":"1194","DOI":"10.1002\/bies.20500","article-title":"Born to bind: the BTB protein-protein interaction domain","volume":"28","author":"Perez-Torrado","year":"2006","journal-title":"Bioessays"},{"key":"key\n\t\t\t\t2019031201360833100_B62","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1038\/ng.750","article-title":"Mutations of the SLX4 gene in Fanconi anemia","volume":"43","author":"Kim","year":"2011","journal-title":"Nat. Genet."},{"key":"key\n\t\t\t\t2019031201360833100_B63","doi-asserted-by":"crossref","first-page":"1124","DOI":"10.1101\/gad.238303.114","article-title":"Roles of SLX1-SLX4, MUS81-EME1, and GEN1 in avoiding genome instability and mitotic catastrophe","volume":"28","author":"Sarbajna","year":"2014","journal-title":"Genes Dev."},{"key":"key\n\t\t\t\t2019031201360833100_B64","doi-asserted-by":"crossref","first-page":"800","DOI":"10.1016\/j.ajhg.2013.04.002","article-title":"Mutations in ERCC4, encoding the DNA-repair endonuclease XPF, cause Fanconi anemia","volume":"92","author":"Bogliolo","year":"2013","journal-title":"Am. J. Hum. Genet."},{"key":"key\n\t\t\t\t2019031201360833100_B65","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1016\/j.ajhg.2013.04.007","article-title":"Malfunction of nuclease ERCC1-XPF results in diverse clinical manifestations and causes Cockayne syndrome, xeroderma pigmentosum, and Fanconi anemia","volume":"92","author":"Kashiyama","year":"2013","journal-title":"Am. J. Hum. Genet."},{"key":"key\n\t\t\t\t2019031201360833100_B66","doi-asserted-by":"crossref","first-page":"3999","DOI":"10.4161\/cc.10.23.18385","article-title":"Orchestrating the nucleases involved in DNA interstrand cross-link (ICL) repair","volume":"10","author":"Sengerova","year":"2011","journal-title":"Cell Cycle"},{"key":"key\n\t\t\t\t2019031201360833100_B67","doi-asserted-by":"crossref","first-page":"1859","DOI":"10.1101\/gad.15699211","article-title":"Human SNM1A and XPF-ERCC1 collaborate to initiate DNA interstrand cross-link repair","volume":"25","author":"Wang","year":"2011","journal-title":"Genes Dev."},{"key":"key\n\t\t\t\t2019031201360833100_B68","doi-asserted-by":"crossref","first-page":"1275","DOI":"10.1074\/jbc.M708072200","article-title":"Processing of a psoralen DNA interstrand cross-link by XPF-ERCC1 complex in vitro","volume":"283","author":"Fisher","year":"2008","journal-title":"J. Biol. Chem."},{"key":"key\n\t\t\t\t2019031201360833100_B69","doi-asserted-by":"crossref","first-page":"6492","DOI":"10.1073\/pnas.1018487108","article-title":"Involvement of SLX4 in interstrand cross-link repair is regulated by the Fanconi anemia pathway","volume":"108","author":"Yamamoto","year":"2011","journal-title":"PNAS"}],"container-title":["Nucleic Acids Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/nar\/article-pdf\/47\/5\/2377\/28041769\/gky1276.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,3,12]],"date-time":"2019-03-12T01:36:23Z","timestamp":1552354583000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/nar\/article\/47\/5\/2377\/5255686"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,12,21]]},"references-count":69,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2018,12,21]]},"published-print":{"date-parts":[[2019,3,18]]}},"URL":"https:\/\/doi.org\/10.1093\/nar\/gky1276","relation":{},"ISSN":["0305-1048","1362-4962"],"issn-type":[{"value":"0305-1048","type":"print"},{"value":"1362-4962","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2019,3,18]]},"published":{"date-parts":[[2018,12,21]]}}}