{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T18:34:59Z","timestamp":1793385299164,"version":"4.5.0"},"reference-count":33,"publisher":"Oxford University Press (OUP)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2000,5,1]]},"DOI":"10.1093\/ndt\/15.5.611","type":"journal-article","created":{"date-parts":[[2002,7,26]],"date-time":"2002-07-26T22:30:06Z","timestamp":1027722606000},"page":"611-618","source":"Crossref","is-referenced-by-count":109,"title":["Wegener's granulomatosis: clinical course in 108 patients with renal involvement"],"prefix":"10.1093","volume":"15","author":[{"given":"Knut","family":"Aasar\u00f8d","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bjarne M.","family":"Iversen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jens","family":"Hammerstr\u00f8m","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leif","family":"Bostad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lars","family":"Vatten","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"St\u00f8rker","family":"J\u00f8rstad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2000,5]]},"reference":[{"key":"key\n\t\t\t\t20180109101344_R1","doi-asserted-by":"crossref","unstructured":"Walton EW. Giant cell granuloma of the respiratory tract (Wegener's granulomatosis). Br Med J1958; 2: 265\u2013270","DOI":"10.1136\/bmj.2.5091.265"},{"key":"key\n\t\t\t\t20180109101344_R2","doi-asserted-by":"crossref","unstructured":"Fauci AS, Haynes BF, Katz P, Wolff SM. Wegener's granulomatosis: prospective clinical and therapeutic experience with 85 patients for 21 years. Ann Intern Med1983; 98: 76\u201385","DOI":"10.7326\/0003-4819-98-1-76"},{"key":"key\n\t\t\t\t20180109101344_R3","doi-asserted-by":"crossref","unstructured":"Hoffman GS, Kerr GS, Leavitt RY et al. Wegener granulomatosis: an analysis of 158 patients [see comments]. Ann Intern Med1992; 116: 488\u2013498","DOI":"10.7326\/0003-4819-116-6-488"},{"key":"key\n\t\t\t\t20180109101344_R4","unstructured":"Scott DG, Bacon PA, Elliott PJ, Tribe CR, Wallington TB. Systemic vasculitis in a district general hospital 1972\u20131980: clinical and laboratory features, classification and prognosis of 80 cases. Q J Med1982; 51: 292\u2013311"},{"key":"key\n\t\t\t\t20180109101344_R5","unstructured":"Kurland LT, Chuang TY, Hunder G. The epidemiology of systemic arteritis. In: Lawrence RC and Shulman LE, eds. The Epidemiology of the Rheumatic Diseases. Gower, New York 1984: 196\u2013205"},{"key":"key\n\t\t\t\t20180109101344_R6","doi-asserted-by":"crossref","unstructured":"van der Woude FJ, Rasmussen N, Lobatto S et al. Autoantibodies against neutrophils and monocytes: tool for diagnosis and marker of disease activity in Wegener's granulomatosis. Lancet1985; 1: 425\u2013429","DOI":"10.1016\/S0140-6736(85)91147-X"},{"key":"key\n\t\t\t\t20180109101344_R7","doi-asserted-by":"crossref","unstructured":"Watts RA, Carruthers DM, Scott DG. Epidemiology of systemic vasculitis: changing incidence or definition? Semin Arthritis Rheum1995; 25: 28\u201334","DOI":"10.1016\/S0049-0172(95)80015-8"},{"key":"key\n\t\t\t\t20180109101344_R8","doi-asserted-by":"crossref","unstructured":"Appel GB, Gee B, Kashgarian M, Hayslett JP. Wegener's granulomatosis\u2014clinical\u2013pathologic correlations and long\u2010term course. Am J Kidney Dis1981; 1: 27\u201337","DOI":"10.1016\/S0272-6386(81)80008-X"},{"key":"key\n\t\t\t\t20180109101344_R9","unstructured":"Luqmani RA, Bacon PA, Beaman M et al. Classical versus non\u2010renal Wegener's granulomatosis. Q J Med1994; 87: 161\u2013167"},{"key":"key\n\t\t\t\t20180109101344_R10","unstructured":"Adu D, Howie AJ, Scott DG, Bacon PA, McGonigle RJ, Michael J. Polyarteritis and the kidney. Q J Med1987; 62: 221\u2013237"},{"key":"key\n\t\t\t\t20180109101344_R11","unstructured":"Andrassy K, Erb A, Koderisch J, Waldherr R, Ritz E. Wegener's granulomatosis with renal involvement: patient survival and correlations between initial renal function, renal histology, therapy and renal outcome. Clin Nephrol1991; 35: 139\u2013147"},{"key":"key\n\t\t\t\t20180109101344_R12","doi-asserted-by":"crossref","unstructured":"Falk RJ, Hogan S, Carey TS, Jennette JC. Clinical course of anti\u2010neutrophil cytoplasmic autoantibody\u2010associated glomerulonephritis and systemic vasculitis. The Glomerular Disease Collaborative Network [see comments]. Ann Intern Med1990; 113: 656\u2013663","DOI":"10.7326\/0003-4819-113-9-656"},{"key":"key\n\t\t\t\t20180109101344_R13","doi-asserted-by":"crossref","unstructured":"Leavitt RY, Fauci AS, Bloch DA et al. The American College of Rheumatology 1990 criteria for the classification of Wegener's granulomatosis. Arthritis Rheum1990; 33: 1101\u20131107","DOI":"10.1002\/art.1780330807"},{"key":"key\n\t\t\t\t20180109101344_R14","doi-asserted-by":"crossref","unstructured":"Sneller MC, Hoffman GS, Talar\u2010Williams C, Kerr GS, Hallahan CW, Fauci AS. An analysis of forty\u2010two Wegener's granulomatosis patients treated with methotrexate and prednisone. Arthritis Rheum1995; 38: 608\u2013613","DOI":"10.1002\/art.1780380505"},{"key":"key\n\t\t\t\t20180109101344_R15","doi-asserted-by":"crossref","unstructured":"Westman KW, Bygren PG, Olsson H, Ranstam J, Wieslander J. Relapse rate, renal survival, and cancer morbidity in patients with Wegener's granulomatosis or microscopic polyangiitis with renal involvement. J Am Soc Nephrol1998; 9: 842\u2013852","DOI":"10.1681\/ASN.V95842"},{"key":"key\n\t\t\t\t20180109101344_R16","doi-asserted-by":"crossref","unstructured":"Nachman PH, Hogan SL, Jennette JC, Falk RJ. Treatment response and relapse in antineutrophil cytoplasmic autoantibody\u2010associated microscopic polyangiitis and glomerulonephritis. J Am Soc Nephrol1996; 7: 33\u201339","DOI":"10.1681\/ASN.V7133"},{"key":"key\n\t\t\t\t20180109101344_R17","unstructured":"Gordon M, Luqmani RA, Adu D et al. Relapses in patients with a systemic vasculitis. Q J Med1993; 86: 779\u2013789"},{"key":"key\n\t\t\t\t20180109101344_R18","unstructured":"Jayne DR, Gaskin G, Pusey CD, Lockwood CM. ANCA and predicting relapse in systemic vasculitis. Q J Med1995; 88: 127\u2013133"},{"key":"key\n\t\t\t\t20180109101344_R19","unstructured":"Geffriaud\u2010Ricouard C, Noel LH, Chauveau D, Houhou S, Grunfeld JP, Lesavre P. Clinical spectrum associated with ANCA of defined antigen specificities in 98 selected patients. Clin Nephrol1993; 39: 125\u2013136"},{"key":"key\n\t\t\t\t20180109101344_R20","doi-asserted-by":"crossref","unstructured":"Franssen C, Gans R, Kallenberg C, Hageluken C, Hoorntje S. Disease spectrum of patients with antineutrophil cytoplasmic autoantibodies of defined specificity: distinct differences between patients with anti\u2010proteinase 3 and anti\u2010myeloperoxidase autoantibodies. J Intern Med1998; 244: 209\u2013216","DOI":"10.1046\/j.1365-2796.1998.00357.x"},{"key":"key\n\t\t\t\t20180109101344_R21","doi-asserted-by":"crossref","unstructured":"Guillevin L, Cordier JF, Lhote F et al. A prospective, multicenter, randomized trial comparing steroids and pulse cyclophosphamide versus steroids and oral cyclophosphamide in the treatment of generalized Wegener's granulomatosis [see comments]. Arthritis Rheum1997; 40: 2187\u20132198","DOI":"10.1002\/art.1780401213"},{"key":"key\n\t\t\t\t20180109101344_R22","doi-asserted-by":"crossref","unstructured":"Jayne DR, Rasmussen N. Treatment of antineutrophil cytoplasm autoantibody\u2010associated systemic vasculitis: initiatives of the European Community Systemic Vasculitis Clinical Trials Study Group. Mayo Clin Proc1997; 72: 737\u2013747","DOI":"10.4065\/72.8.737"},{"key":"key\n\t\t\t\t20180109101344_R23","doi-asserted-by":"crossref","unstructured":"Briedigkeit L, Kettritz R, Gobel U, Natusch R. Prognostic factors in Wegener's granulomatosis. Postgrad Med J1993; 69: 856\u2013861","DOI":"10.1136\/pgmj.69.817.856"},{"key":"key\n\t\t\t\t20180109101344_R24","doi-asserted-by":"crossref","unstructured":"Hogan SL, Nachman PH, Wilkman AS, Jennette JC, Falk RJ. Prognostic markers in patients with antineutrophil cytoplasmic autoantibody\u2010associated microscopic polyangiitis and glomerulonephritis. J Am Soc Nephrol1996; 7: 23\u201332","DOI":"10.1681\/ASN.V7123"},{"key":"key\n\t\t\t\t20180109101344_R25","doi-asserted-by":"crossref","unstructured":"Balow JE. Renal vasculitis [clinical conference]. Kidney Int1985; 27: 954\u2013964","DOI":"10.1038\/ki.1985.104"},{"key":"key\n\t\t\t\t20180109101344_R26","doi-asserted-by":"crossref","unstructured":"Franssen CF, Gans RO, Arends B et al. Differences between anti\u2010myeloperoxidase\u2010 and anti\u2010proteinase 3\u2010associated renal disease. Kidney Int1995; 47: 193\u2013199","DOI":"10.1038\/ki.1995.23"},{"key":"key\n\t\t\t\t20180109101344_R27","doi-asserted-by":"crossref","unstructured":"Matteson EL, Gold KN, Bloch DA, Hunder GG. Long\u2010term survival of patients with Wegener's granulomatosis from the American College of Rheumatology Wegener's Granulomatosis Classification Criteria Cohort. Am J Med1996; 101: 129\u2013134","DOI":"10.1016\/S0002-9343(96)80066-0"},{"key":"key\n\t\t\t\t20180109101344_R28","doi-asserted-by":"crossref","unstructured":"Goodfield NE, Bhandari S, Plant WD, Morley\u2010Davies A, Sutherland GR. Cardiac involvement in Wegener's granulomatosis. Br Heart J1995; 73: 110\u2013115","DOI":"10.1136\/hrt.73.2.110"},{"key":"key\n\t\t\t\t20180109101344_R29","doi-asserted-by":"crossref","unstructured":"Forstot JZ, Overlie PA, Neufeld GK, Harmon CE, Forstot SL. Cardiac complications of Wegener granulomatosis: a case report of complete heart block and review of the literature. Semin Arthritis Rheum1980; 10: 148\u2013154","DOI":"10.1016\/0049-0172(80)90005-0"},{"key":"key\n\t\t\t\t20180109101344_R30","unstructured":"Jarrousse B, Guillevin L, Bindi P et al. Increased risk of Pneumocystis carinii pneumonia in patients with Wegener's granulomatosis [published erratum appears in Clin Exp Rheumatol 1994 Jan\u2013Feb; 12(1): 117]. Clin Exp Rheumatol1993; 11: 615\u2013621"},{"key":"key\n\t\t\t\t20180109101344_R31","doi-asserted-by":"crossref","unstructured":"Pryor BD, Bologna SG, Kahl LE. Risk factors for serious infection during treatment with cyclophosphamide and high\u2010dose corticosteroids for systemic lupus erythematosus [see comments] [published erratum appears in Arthritis Rheum 1997 Sep; 40(9): 1711]. Arthritis Rheum1996; 39: 1475\u20131482","DOI":"10.1002\/art.1780390906"},{"key":"key\n\t\t\t\t20180109101344_R32","doi-asserted-by":"crossref","unstructured":"Talar\u2010Williams C, Hijazi YM, Walther MM et al. Cyclophosphamide\u2010induced cystitis and bladder cancer in patients with Wegener granulomatosis [see comments]. Ann Intern Med1996; 124: 477\u2013484","DOI":"10.7326\/0003-4819-124-5-199603010-00003"},{"key":"key\n\t\t\t\t20180109101344_R33","doi-asserted-by":"crossref","unstructured":"Pedersen\u2010Bjergaard J, Ersboll J, Sorensen HM et al. Risk of acute nonlymphocytic leukemia and preleukemia in patients treated with cyclophosphamide for non\u2010Hodgkin's lymphomas. Comparison with results obtained in patients treated for Hodgkin's disease and ovarian carcinoma with other alkylating agents. Ann Intern Med1985; 103: 195\u2013200","DOI":"10.7326\/0003-4819-103-2-195"}],"container-title":["Nephrology Dialysis Transplantation"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/ndt\/article-pdf\/15\/5\/611\/23367582\/150611.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,5,17]],"date-time":"2021-05-17T16:16:46Z","timestamp":1621268206000},"score":1,"resource":{"primary":{"URL":"http:\/\/academic.oup.com\/ndt\/article\/15\/5\/611\/1849889"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,5,1]]},"references-count":33,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2000,5]]},"published-print":{"date-parts":[[2000,5,1]]}},"URL":"https:\/\/doi.org\/10.1093\/ndt\/15.5.611","relation":{},"ISSN":["1460-2385","0931-0509"],"issn-type":[{"value":"1460-2385","type":"electronic"},{"value":"0931-0509","type":"print"}],"subject":[],"published-other":{"date-parts":[[2000,5]]},"published":{"date-parts":[[2000,5,1]]}}}