{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T12:55:15Z","timestamp":1790686515038,"version":"4.1.0"},"reference-count":53,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2020,5,27]],"date-time":"2020-05-27T00:00:00Z","timestamp":1590537600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,6,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>The objective of this study was to establish if renal transplant outcomes (graft and patient survival) for young adults in England were worse than for other age groups.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Outcomes for all renal transplant recipients in England (n\u2009=\u200926\u00a0874) were collected from Hospital Episode Statistics and the Office for National Statistics databases over 12\u2009years. Graft and patient outcomes, follow-up and admissions were studied for all patients, stratified by age bands.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Young adults (14\u201323\u2009years) had substantially greater likelihood [hazard ratio (HR) = 1.26, 95% confidence interval (CI) 1.10\u20131.19; P\u2009&amp;lt;\u20090.001] of kidney transplant failure than any other age band. They had a higher non-attendance rate for clinic appointments (1.6 versus 1.2\/year; P\u2009&amp;lt; 0.001) and more emergency admissions post-transplantation (25% of young adults on average are admitted each year, compared with 15\u201320% of 34- to 43-year olds). Taking into account deprivation, ethnicity, transplant type and transplant centre, in the 14- to 23-year group, return to dialysis remained significantly worse than all other age bands (HR = 1.41, 95% CI 1.26\u20131.57). For the whole cohort, increasing deprivation related to poorer outcomes and black ethnicity was associated with poorer outcomes. However, neither ethnicity nor deprivation was over-represented in the young adult cohort.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Young adults who receive a kidney transplant have a significant increased likelihood of a return to dialysis in the first 10 years post-transplant when compared with those aged 34\u201343\u2009years in multivariable analysis.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ndt\/gfaa059","type":"journal-article","created":{"date-parts":[[2020,3,3]],"date-time":"2020-03-03T20:19:30Z","timestamp":1583266770000},"page":"1043-1051","source":"Crossref","is-referenced-by-count":33,"title":["Young adults have worse kidney transplant outcomes than other age groups"],"prefix":"10.1093","volume":"35","author":[{"given":"Tanya","family":"Pankhurst","sequence":"first","affiliation":[{"name":"Department of Nephrology, University Hospitals Birmingham, Birmingham, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felicity","family":"Evison","sequence":"first","affiliation":[{"name":"Department of Nephrology, University Hospitals Birmingham, Birmingham, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jemma","family":"Mytton","sequence":"first","affiliation":[{"name":"Department of Nephrology, University Hospitals Birmingham, Birmingham, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samantha","family":"Williamson","sequence":"first","affiliation":[{"name":"Department of Nephrology, University Hospitals Birmingham, Birmingham, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Larissa","family":"Kerecuk","sequence":"first","affiliation":[{"name":"Department of Nephrology, Birmingham Women\u2019s and Children\u2019s NHS Foundation Trust, Birmingham, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Graham","family":"Lipkin","sequence":"first","affiliation":[{"name":"Department of Nephrology, University Hospitals Birmingham, Birmingham, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2020,5,27]]},"reference":[{"key":"2020061010445655800_gfaa059-B1","doi-asserted-by":"crossref","first-page":"904","DOI":"10.1093\/ndt\/gfx046","article-title":"The clinical epidemiology of young adults starting renal replacement therapy in the UK: presentation, management and survival using 15 years of UK Renal Registry data","volume":"32","author":"Hamilton","year":"2017","journal-title":"Nephrol Dial Transplant"},{"key":"2020061010445655800_gfaa059-B2","doi-asserted-by":"crossref","first-page":"e3718","DOI":"10.1136\/bmj.e3718","article-title":"Bridging the gap: an integrated paediatric to adult clinical service for young adults with kidney 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