{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T20:07:43Z","timestamp":1792786063788,"version":"4.5.0"},"reference-count":88,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2022,7,22]],"date-time":"2022-07-22T00:00:00Z","timestamp":1658448000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"DOI":"10.13039\/100013870","name":"Astex Pharmaceuticals","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100013870","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004330","name":"GlaxoSmithKline","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004330","id-type":"DOI","asserted-by":"publisher"}]},{"name":"George Clinicals"},{"DOI":"10.13039\/100009891","name":"International Society of Nephrology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009891","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100001463","name":"American Society of Nephrology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100001463","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,5,31]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Systemic AA amyloidosis is associated with systemic inflammatory processes such as autoimmune disorders or chronic infections. In addition, AA amyloidosis can develop in a localized or systemic form in patients with malignant neoplastic disorders, and usually involves kidneys impacting renal function. Among solid tumors, renal cell carcinoma (RCC) appears to be responsible for one-quarter to half of all cancers associated with amyloidosis. Among other solid cancers, various clinical presentations and pathological types of lung cancer and basal cell carcinoma skin were reported with AA amyloidosis more often than isolated case reports on other cancers with AA amyloidosis. Symptoms from kidney involvement rather than from the tumor per se were the presenting manifestations in cases of RCC associated with AA amyloidosis. Among hematological malignancies, clonal B cell\/plasma cell dyscrasias such as monoclonal gammopathy and lymphoma were noted to be associated with AA amyloidosis. In addition, AA amyloidosis was reported in a substantial number of cases treated with immune checkpoint inhibitors such as pembrolizumab and nivolumab. The mechanism of association of cancer and AA amyloidosis seems to be mediated by the immune response exacerbated from the tumor and its microenvironment or immune therapy. The mainstay of treatment consists of therapy directed against the underlying malignancy or careful withdrawal of the offending agent. This review will discuss this rare but highly morbid clinical condition.<\/jats:p>","DOI":"10.1093\/ndt\/gfac217","type":"journal-article","created":{"date-parts":[[2022,7,22]],"date-time":"2022-07-22T14:49:03Z","timestamp":1658501343000},"page":"1366-1374","source":"Crossref","is-referenced-by-count":24,"title":["AA amyloidosis associated with cancers"],"prefix":"10.1093","volume":"38","author":[{"given":"Joyita","family":"Bharati","sequence":"first","affiliation":[{"name":"Department of Nephrology, Post Graduate Institute of Medical Education and Research , Chandigarh , India"},{"name":"Glomerular Center at Northwell Health, Division of Kidney Diseases and Hypertension, Department of Medicine, Donald and Barbara Zucker School of Medicine at Hofstra\/Northwell , Great Neck, NY , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oscar B","family":"Lahoud","sequence":"additional","affiliation":[{"name":"Adult Bone Marrow Transplant Service, Department of Medicine, Memorial Sloan Kettering Cancer Center , New York, NY , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1578-0524","authenticated-orcid":false,"given":"Kenar D","family":"Jhaveri","sequence":"additional","affiliation":[{"name":"Glomerular Center at Northwell Health, Division of Kidney Diseases and Hypertension, Department of Medicine, Donald and Barbara Zucker School of Medicine at Hofstra\/Northwell , Great Neck, NY , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6249-9837","authenticated-orcid":false,"given":"Hassan","family":"Izzedine","sequence":"additional","affiliation":[{"name":"Department of Nephrology, Peupliers Private Hospital, Ramsay G\u00e9n\u00e9rale de Sant\u00e9 , Paris , France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2022,7,22]]},"reference":[{"key":"2023053100321606100_bib1","doi-asserted-by":"crossref","first-page":"1817","DOI":"10.1182\/blood.V79.7.1817.1817","article-title":"Incidence and natural history of primary systemic amyloidosis in Olmsted County, Minnesota, 1950 through 1989","volume":"79","author":"Kyle","year":"1992","journal-title":"Blood"},{"key":"2023053100321606100_bib2","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1080\/13506129.2017.1342235","article-title":"Changing epidemiology of AA amyloidosis: clinical observations over 25 years at a single national referral centre","volume":"24","author":"Lane","year":"2017","journal-title":"Amyloid"},{"key":"2023053100321606100_bib3","doi-asserted-by":"crossref","first-page":"369","DOI":"10.2147\/CLEP.S39981","article-title":"Systemic AA amyloidosis: epidemiology, diagnosis, and management","volume":"6","author":"Real de As\u00faa","year":"2014","journal-title":"Clin Epidemiol"},{"key":"2023053100321606100_bib4","doi-asserted-by":"crossref","first-page":"958","DOI":"10.7326\/0003-4819-55-6-958","article-title":"Amyloidosis in association with neoplastic disease. Report of an unusual case and clinicopathological experience at Memorial Center for Cancer and Allied Diseases during eleven years (1948-1958)","volume":"55","author":"Kimball","year":"1961","journal-title":"Ann Intern Med"},{"key":"2023053100321606100_bib5","doi-asserted-by":"crossref","first-page":"2361","DOI":"10.1056\/NEJMoa070265","article-title":"Natural history and outcome in systemic AA amyloidosis","volume":"356","author":"Lachmann","year":"2007","journal-title":"N Engl J Med"},{"key":"2023053100321606100_bib6","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1111\/j.0954-6820.1940.tb09080.x","article-title":"On amyloidosis induced by tumors of the kidney","volume":"104","author":"Ask-Upmark","year":"1940","journal-title":"Acta Med Scand"},{"key":"2023053100321606100_bib7","first-page":"411","article-title":"Systemic amyloidosis and non-hematologic malignancy in a large autopsy series","volume":"89","author":"Dictor","year":"1981","journal-title":"Acta Pathol Microbiol Scand A"},{"key":"2023053100321606100_bib8","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1136\/jcp.19.6.539","article-title":"Systemic amyloidosis and malignant disease","volume":"19","author":"Azzopardi","year":"1966","journal-title":"J Clin Pathol"},{"key":"2023053100321606100_bib9","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1038\/ki.2012.484","article-title":"Glomerular diseases seen with cancer and chemotherapy: a narrative review","volume":"84","author":"Jhaveri","year":"2013","journal-title":"Kidney Int"},{"key":"2023053100321606100_bib10","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1210\/jcem-19-1-152","article-title":"Medullary (solid) carcinoma of the thyroid; a clinicopathologic entity","volume":"19","author":"Hazard","year":"1959","journal-title":"J Clin Endocrinol Metab"},{"key":"2023053100321606100_bib11","first-page":"623","article-title":"Amyloidosis of functioning islet cell adenomas of the pancreas","volume":"41","author":"Porta","year":"1962","journal-title":"Am J Pathol"},{"key":"2023053100321606100_bib12","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1016\/0030-4220(65)90240-9","article-title":"Amyloid-containing odontogenic tumors","volume":"20","author":"Vickers","year":"1965","journal-title":"Oral Surg Oral Med Oral Pathol"},{"key":"2023053100321606100_bib13","first-page":"212","article-title":"Amyloid in polypeptide hormone-producing tumors","volume":"37","author":"Westermark","year":"1977","journal-title":"Lab Invest"},{"key":"2023053100321606100_bib14","first-page":"87A","article-title":"Interstitial amyloid in pheochromocytomas","volume":"58","author":"Steinhoff","year":"1988","journal-title":"Lab Invest"},{"key":"2023053100321606100_bib15","doi-asserted-by":"crossref","first-page":"722","DOI":"10.1046\/j.1464-410x.1999.00071.x","article-title":"Localized amyloidosis of the urethra with transitional cell carcinoma of the bladder","volume":"83","author":"Biyani","year":"1999","journal-title":"BJU Int"},{"key":"2023053100321606100_bib16","doi-asserted-by":"crossref","first-page":"153","DOI":"10.2739\/kurumemedj.49.153","article-title":"Early gastric carcinoma associated with amyloidosis: a case report","volume":"49","author":"Aoyagi","year":"2002","journal-title":"Kurume Med J"},{"key":"2023053100321606100_bib17","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1016\/0090-4295(80)90382-9","article-title":"Primary amyloidosis of renal pelvis and renal cortical adenoma","volume":"XV","author":"Gelbard","year":"1980","journal-title":"Urology"},{"key":"2023053100321606100_bib18","doi-asserted-by":"crossref","first-page":"1833","DOI":"10.1002\/1097-0142(19831115)52:10<1833::AID-CNCR2820521012>3.0.CO;2-O","article-title":"Localized amyloidosis in basal cell carcinoma. A pathologic study","volume":"52","author":"Looi","year":"1983","journal-title":"Cancer"},{"key":"2023053100321606100_bib19","doi-asserted-by":"crossref","first-page":"1515","DOI":"10.2215\/CJN.10491012","article-title":"Renal amyloidosis: origin and clinicopathologic correlations of 474 recent cases","volume":"8","author":"Said","year":"2013","journal-title":"Clin J Am Soc Nephrol"},{"key":"2023053100321606100_bib20","first-page":"107","article-title":"The systemic amyloidoses: an overview","volume":"45","author":"Falk","year":"2000","journal-title":"Adv Intern Med"},{"key":"2023053100321606100_bib21","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1007\/s13730-013-0088-8","article-title":"Renal cell carcinoma presenting as AA amyloidosis: a case report and review of the literature","volume":"3","author":"Babu","year":"2014","journal-title":"CEN Case Rep"},{"key":"2023053100321606100_bib22","doi-asserted-by":"crossref","first-page":"882","DOI":"10.1016\/j.ekir.2019.02.017","article-title":"Cancer-associated AA amyloidosis presenting as crescentic glomerulonephritis","volume":"4","author":"Zuckerman","year":"2019","journal-title":"Kidney Int Rep"},{"key":"2023053100321606100_bib23","doi-asserted-by":"crossref","first-page":"1510","DOI":"10.1038\/sj.ki.5001790","article-title":"Membranous nephropathy and cancer: epidemiologic evidence and determinants of high-risk cancer association","volume":"70","author":"Lefaucheur","year":"2006","journal-title":"Kidney Int"},{"key":"2023053100321606100_bib24","doi-asserted-by":"crossref","first-page":"574","DOI":"10.1093\/ndt\/gfg616","article-title":"Distribution of glomerular IgG subclass deposits in malignancy-associated membranous nephropathy","volume":"19","author":"Ohtani","year":"2004","journal-title":"Nephrol Dial Transplant"},{"key":"2023053100321606100_bib25","doi-asserted-by":"crossref","first-page":"197","DOI":"10.3109\/13506129.2012.712926","article-title":"Systemic AA amyloidosis in a patient with lung metastasis from renal cell carcinoma","volume":"19","author":"Nobata","year":"2012","journal-title":"Amyloid"},{"key":"2023053100321606100_bib26","first-page":"897","article-title":"Interleukin-1 and its effects on the liver","volume-title":"The Liver: Biology and Pathobiology","author":"Dinarello","year":"1988"},{"key":"2023053100321606100_bib27","doi-asserted-by":"crossref","first-page":"898","DOI":"10.1056\/NEJM199709253371306","article-title":"The systemic amyloidoses","volume":"337","author":"Falk","year":"1997","journal-title":"N Engl J Med"},{"key":"2023053100321606100_bib28","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/S0140-6736(00)05252-1","article-title":"Amyloid load and clinical outcome in AA amyloidosis in relation to circulating concentration of serum amyloid A protein","volume":"358","author":"Gillmore","year":"2001","journal-title":"Lancet"},{"key":"2023053100321606100_bib29","doi-asserted-by":"crossref","first-page":"1391","DOI":"10.1136\/bmj.286.6375.1391","article-title":"Wegelius O. Correlation of persistently high serum amyloid A protein and C-reactive protein concentrations with rapid progression of secondary amyloidosis","volume":"286","author":"Falk","year":"1983","journal-title":"Br Med Jr (Clin Res Ed)"},{"key":"2023053100321606100_bib30","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1111\/j.1365-3083.1984.tb00919.x","article-title":"Acute phase proteins or tumour markers","volume":"19","author":"Weinstein","year":"1984","journal-title":"Scand J Immunol"},{"key":"2023053100321606100_bib31","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1002\/cncr.24838","article-title":"Serum amyloid A: a novel biomarker for endometrial cancer","volume":"116","author":"Cocco","year":"2010","journal-title":"Cancer"},{"key":"2023053100321606100_bib32","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1016\/j.lungcan.2008.07.018","article-title":"Interleukin-6-producing undifferentiated thymic carcinoma with neuroendocrine features","volume":"63","author":"Suzuki","year":"2009","journal-title":"Lung Cancer"},{"key":"2023053100321606100_bib33","first-page":"2260","article-title":"FK506 inhibits murine AA amyloidosis: possible involvement of T cells in amyloidogenesis","volume":"33","author":"Ueda","year":"2006","journal-title":"J Rheumatol"},{"key":"2023053100321606100_bib34","doi-asserted-by":"crossref","first-page":"383","DOI":"10.7326\/0003-4819-91-3-383","article-title":"Serum amyloid A to monitor cancer dissemination","volume":"91","author":"Rosenthal","year":"1979","journal-title":"Ann Intern Med"},{"key":"2023053100321606100_bib35","doi-asserted-by":"crossref","first-page":"798","DOI":"10.1136\/jcp.36.7.798","article-title":"Comparison of serum amyloid A protein and C-reactive protein concentration in cancer and nonmalignant disease","volume":"36","author":"Raynes","year":"1983","journal-title":"J Clin Pathol"},{"key":"2023053100321606100_bib36","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.canlet.2008.04.022","article-title":"Serum amyloid A as indicator of distant metastases but not as early tumor marker in patients with renal cell carcinoma","volume":"269","author":"Ramankulov","year":"2008","journal-title":"Cancer Lett"},{"key":"2023053100321606100_bib37","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1097\/00005792-199107000-00002","article-title":"Secondary systemic amyloidosis: response and survival in 64 patients","volume":"70","author":"Gertz","year":"1991;","journal-title":"Medicine (Baltimore)"},{"key":"2023053100321606100_bib38","doi-asserted-by":"crossref","first-page":"2361","DOI":"10.1056\/NEJMoa070265","article-title":"Natural history and outcome in systemic AA amyloidosis","volume":"356","author":"Lachmann","year":"2007","journal-title":"N Engl J Med"},{"key":"2023053100321606100_bib39","doi-asserted-by":"crossref","first-page":"1207","DOI":"10.1016\/S0272-6386(00)70059-X","article-title":"Remission of nephrotic syndrome after removal of localized Castleman's disease","volume":"35","author":"Keven","year":"2000","journal-title":"Am J Kidney Dis"},{"key":"2023053100321606100_bib40","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1080\/13506120600876930","article-title":"Histopathological regression of systemic AA amyloidosis after surgical treatment of a localized Castleman's disease","volume":"13","author":"Shimojima","year":"2006","journal-title":"Amyloid"},{"key":"2023053100321606100_bib41","first-page":"225","article-title":"Remission of nephrotic syndrome in amyloidosis associated with a hypernephroma","volume":"32","author":"Tang","year":"1989","journal-title":"Clin Nephrol"},{"key":"2023053100321606100_bib42","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/S0046-8177(83)80016-1","article-title":"Renal cell carcinoma and systemic amyloidosis: demonstration of AA protein and review of the literature","volume":"14","author":"Vanatta","year":"1983","journal-title":"Hum Pathol"},{"key":"2023053100321606100_bib43","doi-asserted-by":"crossref","first-page":"1156","DOI":"10.3332\/ecancer.2020.1156","article-title":"Advanced systemic amyloidosis secondary to metastatic renal cell carcinoma","volume":"14","author":"Algarra","year":"2020","journal-title":"Ecancermedicalscience"},{"key":"2023053100321606100_bib44","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1080\/17843286.1960.11717596","article-title":"Amyloidosis secondary to renal carcinoma. Clinical study of 3 cases","volume":"15","author":"Bogaert","year":"1960","journal-title":"Acta Clin Belg"},{"key":"2023053100321606100_bib45","first-page":"1541","article-title":"Spleno-hepatic amyloidosis and cancer of the kidney. Study of local plasmocytosis and of reticulinic lesions","volume":"68","author":"Picard","year":"1960","journal-title":"Presse Med"},{"key":"2023053100321606100_bib46","doi-asserted-by":"crossref","first-page":"1778","DOI":"10.1016\/S0022-5347(17)37026-X","article-title":"Interleukin-6 in renal cell carcinoma","volume":"148","author":"Tsukamoto","year":"1992","journal-title":"J Urol"},{"key":"2023053100321606100_bib47","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1016\/0014-5793(89)80805-1","article-title":"Interleukin-6 (IL-6) functions as an in vitro autocrine growth factor in renal cell carcinomas","volume":"250","author":"Miki","year":"1989","journal-title":"FEBS Lett"},{"key":"2023053100321606100_bib48","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1056\/NEJM197001152820304","article-title":"Remission of the nephrotic syndrome in renal amyloidosis","volume":"282","author":"Lowenstein","year":"1970;","journal-title":"N Engl J Med"},{"key":"2023053100321606100_bib49","doi-asserted-by":"crossref","first-page":"2624","DOI":"10.1200\/JCO.2003.11.021","article-title":"Some unusual paraneoplastic syndromes: case 4. Paraneoplastic nephrotic syndrome in a patient with lung cancer","volume":"21","author":"Ebert","year":"2003","journal-title":"J Clin Oncol"},{"key":"2023053100321606100_bib50","doi-asserted-by":"crossref","first-page":"836","DOI":"10.1186\/s12885-016-2882-0","article-title":"Increased serum amyloid A as potential diagnostic marker for lung cancer: a meta-analysis based on nine studies","volume":"16","author":"Biaoxue","year":"2016","journal-title":"BMC Cancer"},{"key":"2023053100321606100_bib51","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1136\/thx.45.2.156","article-title":"Systemic amyloid associated with carcinoma of the bronchus","volume":"45","author":"Richmond","year":"1990","journal-title":"Thorax"},{"key":"2023053100321606100_bib52","doi-asserted-by":"crossref","first-page":"e25961","DOI":"10.1097\/MD.0000000000025961","article-title":"Lung cancer combined with diffuse peritoneal and mesenteric amyloidosis detected on 18F-FDG PET\/CT: a case report","volume":"100","author":"Wang","year":"2021","journal-title":"Medicine (Baltimore)"},{"key":"2023053100321606100_bib53","first-page":"279","article-title":"Different glomerulopathies accompanying non-small cell lung cancer","volume":"72","author":"Paydas","year":"2005","journal-title":"Mount Sinai J Med"},{"key":"2023053100321606100_bib54","first-page":"831","article-title":"Nephrotic syndrome associated with lung cancer: a rare case of malignancy associated with AA amyloidosis","volume":"2013","author":"Gueutin","year":"2013","journal-title":"Case Rep Nephrol"},{"key":"2023053100321606100_bib55","first-page":"191","article-title":"AA amylosis and the nephrotic syndrome complicating a pulmonary epidermoid carcinoma","volume":"6","author":"Meyrier","year":"1985","journal-title":"Nephrologie"},{"key":"2023053100321606100_bib56","doi-asserted-by":"crossref","first-page":"1031","DOI":"10.1093\/ndt\/gfg063","article-title":"Carcinoma of the bronchus presenting as renal failure secondary to amyloidosis","volume":"18","author":"Garthwaite","year":"2003","journal-title":"Nephrol Dial Transplant"},{"key":"2023053100321606100_bib57","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1038\/modpathol.3880099","article-title":"Extragastrointestinal (soft tissue) stromal tumors: an analysis of 48 cases with emphasis on histologic predictors of outcome","volume":"13","author":"Reith","year":"2000","journal-title":"Mod Pathol"},{"key":"2023053100321606100_bib58","doi-asserted-by":"crossref","first-page":"470","DOI":"10.5858\/2003-127-0470-SAAGST","article-title":"Secondary amyloidosis and gastrointestinal stromal tumors. A case report and discussion of pathogenesis","volume":"127","author":"Overstreet","year":"2003","journal-title":"Arch Pathol Lab Med"},{"key":"2023053100321606100_bib59","doi-asserted-by":"crossref","first-page":"1517","DOI":"10.1093\/ndt\/16.7.1517","article-title":"Honkanen E. Renal failure and nephrotic syndrome associated with gastrointestinal stromal tumour (GIST) \u2013 a rare cause of AA amyloidosis","volume":"16","author":"Jaakkola","year":"2001","journal-title":"Nephrol Dial Transplant"},{"key":"2023053100321606100_bib60","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1093\/ajcp\/78.4.527","article-title":"Multiple endocrine neoplasia: pituitary adenoma, multicentric papillary thyroid carcinoma, bilateral carotid body paraganglioma, parathyroid hyperplasia, gastric leiomyoma and systemic amyloidosis","volume":"78","author":"Larraza-Hernandez","year":"1982","journal-title":"Am J Clin Pathol"},{"key":"2023053100321606100_bib61","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1093\/ajcp\/103.1.90","article-title":"Extranodal follicular dendritic cell sarcoma of the gastrointestinal tract. Morphologic, immunohistochemical, and ultrastructural analysis of two cases","volume":"103","author":"Hollowood","year":"1995","journal-title":"Am J Clin Pathol"},{"key":"2023053100321606100_bib62","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1067\/msy.2001.113441","article-title":"Retroperitoneal follicular dendritic cell sarcoma presenting as secondary amyloidosis","volume":"130","author":"Chiaramonte","year":"2001","journal-title":"Surgery"},{"key":"2023053100321606100_bib63","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1053\/ajkd.2002.34545","article-title":"Systemic amyloidosis associated with pleomorphic sarcoma of the spleen and remission of nephrotic syndrome after removal of the tumor","volume":"40","author":"Agha","year":"2002","journal-title":"Am J Kidney Dis"},{"key":"2023053100321606100_bib64","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1159\/000052417","article-title":"Small cell carcinoma of the urinary bladder: presentation of 23 cases and review of 134 published cases","volume":"39","author":"Trias","year":"2001","journal-title":"Eur Urol"},{"key":"2023053100321606100_bib65","doi-asserted-by":"crossref","first-page":"2453","DOI":"10.1093\/ndt\/gfg391","article-title":"Systemic AA amyloidosis and nephrotic syndrome associated with small cell carcinoma of the bladder","volume":"18","author":"Kanat","year":"2003","journal-title":"Nephrol Dial Transplant"},{"key":"2023053100321606100_bib66","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1111\/j.1440-1797.2006.00538.x","article-title":"Synchronous carcinomas of stomach and bladder together with AA amyloidosis","volume":"11","author":"Ersoy","year":"2006","journal-title":"Nephrology (Carlton)"},{"key":"2023053100321606100_bib67","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1136\/pgmj.70.825.505","article-title":"Systemic amyloidosis and ovarian carcinoma","volume":"70","author":"Fernandez-Miranda","year":"1994","journal-title":"Postgrad Med J"},{"key":"2023053100321606100_bib68","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1373\/clinchem.2004.041087","article-title":"Identification of serum amyloid A as a biomarker to distinguish prostate cancer patients with bone lesions","volume":"51","author":"Le","year":"2005","journal-title":"Clin Chem"},{"key":"2023053100321606100_bib69","first-page":"617","article-title":"Secondary amyloidosis and eosinophilia in a patient with uterine leiomyosarcoma","volume":"35","author":"Onishi","year":"2005","journal-title":"J Clin Oncol"},{"key":"2023053100321606100_bib70","doi-asserted-by":"crossref","first-page":"564","DOI":"10.2340\/0001555563564567","article-title":"Giant basal cell carcinoma with metastasis and secondary amyloidos: report of case","volume":"63","author":"Beck","year":"1983","journal-title":"Acta Derm Venereol"},{"key":"2023053100321606100_bib71","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1111\/j.1346-8138.1996.tb04025.x","article-title":"Giant basal cell carcinoma associated with systemic amyloidosis","volume":"23","author":"Yamamoto","year":"1996","journal-title":"J Dermatol"},{"key":"2023053100321606100_bib72","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1081\/JDI-120022562","article-title":"Permanent improvement of renal dysfunction and proteinuria with colchicine in a patient with tumoral amyloidosis and basal cell carcinoma","volume":"25","author":"Balal","year":"2003","journal-title":"Ren Fail"},{"key":"2023053100321606100_bib73","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1016\/S0168-8278(86)80056-3","article-title":"Systemic reactive amyloidosis caused by hepatocellular adenoma. A case report","volume":"2","author":"Thysell","year":"1986","journal-title":"J Hepatol"},{"key":"2023053100321606100_bib74","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1111\/j.1600-0676.1995.tb00665.x","article-title":"Systemic AA amyloidosis induced by oral contraceptive-associated hepatocellular adenoma: a 13-year follow up","volume":"15","author":"Cosme","year":"1995","journal-title":"Liver"},{"key":"2023053100321606100_bib75","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1136\/gut.31.3.361","article-title":"Systemic AA amyloidosis induced by liver cell adenoma","volume":"31","author":"Fievet","year":"1990","journal-title":"Gut"},{"key":"2023053100321606100_bib76","first-page":"250604","article-title":"The hidden cost of untreated paragangliomas of the head and neck: systemic reactive (AA) amyloidosis","volume":"2015","author":"Dervisoglu","year":"2015","journal-title":"Case Rep Nephrol"},{"key":"2023053100321606100_bib77","first-page":"e14817","article-title":"AA amyloidosis complicating monoclonal gammopathies, an unusual feature validating the concept of \u201cmonoclonal gammopathy of inflammatory significance\u201d?","volume":"75","author":"79.","year":"2021","journal-title":"Int J Clin Pract"},{"key":"2023053100321606100_bib78","doi-asserted-by":"crossref","first-page":"1191","DOI":"10.1053\/j.ajkd.2010.07.009","article-title":"The spectrum of kidney involvement in lymphoma: a case report and review of the literature","volume":"56","author":"Cohen","year":"2010","journal-title":"Am J Kidney Dis"},{"key":"2023053100321606100_bib79","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1111\/bjh.15269","article-title":"Successful treatment of systemic AA amyloidosis associated with underlying Hodgkin lymphoma","volume":"182","author":"Manwani","year":"2018","journal-title":"Br J Haematol"},{"key":"2023053100321606100_bib80","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1111\/j.1365-2257.2006.00795.x","article-title":"Secondary amyloidosis causing nephrotic syndrome in a patient with non-Hodgkin's lymphoma: quite a rare diagnosis","volume":"28","author":"Pamuk","year":"2006","journal-title":"Clin Lab Haematol"},{"key":"2023053100321606100_bib81","first-page":"93","article-title":"Successful treatment of AA amyloidosis secondary to Hodgkin's disease with 4\u2032-iodo-4\u2032-deoxydoxorubicin","volume":"84","author":"P\u00e9rez Equiza","year":"1999","journal-title":"Haematologica"},{"key":"2023053100321606100_bib82","first-page":"677","article-title":"Renal amyloidosis in a child with Hodgkin disease","volume":"39","author":"Thavaraj","year":"2002","journal-title":"Indian Pediatr"},{"key":"2023053100321606100_bib83","first-page":"297","article-title":"Przypadek amyloidozy wt\u00f3rnej w przebiegu ziarnicy z\u0142o\u015bliwej [A case of secondary amyloidosis in Hodgkin's disease]","volume":"51","author":"Bienia","year":"1996","journal-title":"Pol Tyg Lek"},{"key":"2023053100321606100_bib84","doi-asserted-by":"crossref","first-page":"1794","DOI":"10.3109\/10428194.2012.751531","article-title":"Gastrointestinal AA amyloidosis following allogeneic hematopoietic stem cell transplant in a patient with chronic myelogenous leukemia","volume":"54","author":"Honda","year":"2013","journal-title":"Leuk Lymphoma"},{"key":"2023053100321606100_bib85","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1002\/ajh.23413","article-title":"Systemic amyloidosis associated with chronic lymphocytic leukemia\/small lymphocytic lymphoma","volume":"88","author":"Kourelis","year":"2013","journal-title":"Am J Hematol"},{"key":"2023053100321606100_bib86","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1186\/s40425-018-0478-8","article-title":"Nephrotoxicity of immune checkpoint inhibitors beyond tubulointerstitial nephritis: single-center experience","volume":"7","author":"Mamlouk","year":"2019","journal-title":"J Immunother Cancer"},{"key":"2023053100321606100_bib87","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1177\/2399369320907598","article-title":"Immune checkpoint inhibitor\u2013associated renal amyloid A amyloidosis: a case series and review of the literature","volume":"4","author":"Lapman","year":"2020","journal-title":"J Onco-Nephrol"},{"key":"2023053100321606100_bib88","first-page":"142","article-title":"Adrenal carcinoma causing secondary amyloidosis: report of the first case in the literature","volume":"61","author":"Altiparmak","year":"2003","journal-title":"Neth J Med"}],"container-title":["Nephrology Dialysis Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/ndt\/advance-article-pdf\/doi\/10.1093\/ndt\/gfac217\/45688095\/gfac217.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ndt\/article-pdf\/38\/6\/1366\/50463128\/gfac217.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ndt\/article-pdf\/38\/6\/1366\/50463128\/gfac217.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,24]],"date-time":"2023-11-24T16:59:36Z","timestamp":1700845176000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ndt\/article\/38\/6\/1366\/6648712"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,7,22]]},"references-count":88,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2022,7,22]]},"published-print":{"date-parts":[[2023,5,31]]}},"URL":"https:\/\/doi.org\/10.1093\/ndt\/gfac217","relation":{},"ISSN":["0931-0509","1460-2385"],"issn-type":[{"value":"0931-0509","type":"print"},{"value":"1460-2385","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2023,6]]},"published":{"date-parts":[[2022,7,22]]}}}