{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T16:26:57Z","timestamp":1791822417488,"version":"4.3.4"},"reference-count":52,"publisher":"Oxford University Press (OUP)","issue":"12","license":[{"start":{"date-parts":[[2024,4,17]],"date-time":"2024-04-17T00:00:00Z","timestamp":1713312000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,11,27]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Chronic kidney disease (CKD) is a growing global health concern. Recent research has indicated sex disparities in CKD-related complications, yet the impact of sex differences on critical kidney function levels that trigger these complications and mortality remains inadequately documented.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>We investigated sex-specific disparities in CKD-related complications and mortality according to estimated glomerular filtration rate (eGFR) levels. We analyzed National Health and Nutrition Examination Survey (NHANES) data spanning from 1999 to 2018, including adult participants with an eGFR of 15\u2013150\u00a0mL\/min\/1.73 m2. The outcomes were CKD-related complications [hypertension, anaemia, cardiovascular (CV) diseases, acidosis, hyperphosphatemia, hyperparathyroidism] and all-cause and cause-specific mortality (CV mortality and non-CV mortality). Sex-stratified multivariable logistic and Cox regression models yielded odds ratios and hazard ratios for the relationship between eGFR categories and outcomes. Sex-stratified natural splines were used to explore the relationship between continuous eGFR and outcomes and identified eGFR thresholds of statistical significance.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>The study included 49\u00a0558 participants (50.3% women, 49.7% men). Multivariable logistic regression demonstrated a significant eGFR association with all CKD-related complications, exhibiting a linear trend across eGFR categories. Modelling eGFR as a natural spline revealed varied significance thresholds between sexes for anaemia and hyperparathyroidism. Additionally, the eGFR\u2013hyperphosphatemia association was more pronounced in men. We observed substantial but not statistically significant differences between men and women in the thresholds of statistical significance for CV (significance appeared at a higher eGFR in men) and non-CV mortality (significance appeared at a higher eGFR in women).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Research shows sex disparities in most CKD-related complications. Men develop anaemia and hyperparathyroidism earlier; women show a steeper anaemia increase. Men have higher CV mortality risk. As eGFR decreased, men faced a higher risk of CV mortality at a higher eGFR threshold than women.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ndt\/gfae087","type":"journal-article","created":{"date-parts":[[2024,4,18]],"date-time":"2024-04-18T02:05:49Z","timestamp":1713405949000},"page":"2005-2015","source":"Crossref","is-referenced-by-count":16,"title":["Sex differences in chronic kidney disease\u2013related complications and mortality across levels of glomerular filtration rate"],"prefix":"10.1093","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2298-1420","authenticated-orcid":false,"given":"Gianmarco","family":"Lombardi","sequence":"first","affiliation":[{"name":"U.O.C. Nefrologia, Department of Medicine, Azienda Ospedaliera Universitaria Integrata di Verona, University of Verona , Verona ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1379-022X","authenticated-orcid":false,"given":"Pietro Manuel","family":"Ferraro","sequence":"additional","affiliation":[{"name":"U.O.C. Nefrologia, Department of Medicine, Azienda Ospedaliera Universitaria Integrata di Verona, University of Verona , Verona ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elisa","family":"De Tomi","sequence":"additional","affiliation":[{"name":"U.O.C. Nefrologia, Department of Medicine, Azienda Ospedaliera Universitaria Integrata di Verona, University of Verona , Verona ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9288-4111","authenticated-orcid":false,"given":"Matteo","family":"Bargagli","sequence":"additional","affiliation":[{"name":"Department of Nephrology and Hypertension, Inselspital, Bern University Hospital, University of Bern , Bern ,","place":["Switzerland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6044-7256","authenticated-orcid":false,"given":"Andrea","family":"Spasiano","sequence":"additional","affiliation":[{"name":"Dipartimento Universitario di Medicina e Chirurgia Traslazionale, Universit\u00e0 Cattolica del Sacro Cuore , Rome ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giovanni","family":"Gambaro","sequence":"additional","affiliation":[{"name":"U.O.C. Nefrologia, Department of Medicine, Azienda Ospedaliera Universitaria Integrata di Verona, University of Verona , Verona ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2024,4,17]]},"reference":[{"key":"2024112623560859700_bib1","doi-asserted-by":"publisher","first-page":"1296","DOI":"10.1016\/S0140-6736(09)62004-3","article-title":"Early recognition and prevention of chronic kidney disease","volume":"375","author":"James","year":"2010","journal-title":"Lancet North Am Ed"},{"key":"2024112623560859700_bib2","doi-asserted-by":"publisher","first-page":"709","DOI":"10.1016\/S0140-6736(20)30045-3","article-title":"Global, regional, and national burden of chronic kidney disease, 1990-2017: A systematic analysis for the Global Burden of Disease Study 2017","volume":"395","author":"GBD Chronic Kidney Disease Collaboration","year":"2020","journal-title":"Lancet North Am Ed"},{"key":"2024112623560859700_bib3","doi-asserted-by":"publisher","first-page":"868","DOI":"10.1053\/j.ajkd.2019.08.026","article-title":"Perceived health and quality of life in patients with CKD, including those with kidney failure: findings from national surveys in France","volume":"75","author":"Legrand","year":"2020","journal-title":"Am J Kidney Dis"},{"key":"2024112623560859700_bib4","doi-asserted-by":"publisher","first-page":"46","DOI":"10.1016\/j.yfrne.2017.04.001","article-title":"Sex differences in cardiovascular disease\u2014impact on care and outcomes","volume":"46","author":"Humphries","year":"2017","journal-title":"Front Neuroendocrinol"},{"key":"2024112623560859700_bib5","doi-asserted-by":"publisher","first-page":"2145","DOI":"10.1161\/CIRCULATIONAHA.110.968792","article-title":"Sex\/gender differences in cardiovascular disease prevention: what a difference a decade makes","volume":"124","author":"Mosca","year":"2011","journal-title":"Circulation"},{"key":"2024112623560859700_bib6","doi-asserted-by":"publisher","first-page":"185","DOI":"10.1038\/nrneph.2017.189","article-title":"Sex-specific differences in hypertension and associated cardiovascular disease","volume":"14","author":"Colafella","year":"2018","journal-title":"Nat Rev Nephrol"},{"key":"2024112623560859700_bib7","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1016\/S0140-6736(11)60679-X","article-title":"National, regional, and global trends in fasting plasma glucose and diabetes prevalence since 1980: systematic analysis of health examination surveys and epidemiological studies with 370 country-years and 2\u00b77 million participants","volume":"378","author":"Danaei","year":"2011","journal-title":"Lancet North Am Ed"},{"key":"2024112623560859700_bib8","doi-asserted-by":"publisher","first-page":"813","DOI":"10.1164\/rccm.201512-2379ED","article-title":"Sex differences in chronic obstructive pulmonary disease mechanisms","volume":"193","author":"Barnes","year":"2016","journal-title":"Am J Respir Crit Care Med"},{"key":"2024112623560859700_bib9","doi-asserted-by":"publisher","first-page":"151","DOI":"10.1038\/nrneph.2017.181","article-title":"Sex and gender disparities in the epidemiology and outcomes of chronic kidney disease","volume":"14","author":"Carrero","year":"2018","journal-title":"Nat Rev Nephrol"},{"key":"2024112623560859700_bib10","doi-asserted-by":"publisher","first-page":"245","DOI":"10.1159\/000342210","article-title":"Risk factor, age and sex differences in chronic kidney disease prevalence in a diabetic cohort: the pathways study","volume":"36","author":"Yu","year":"2012","journal-title":"Am J Nephrol"},{"key":"2024112623560859700_bib11","doi-asserted-by":"publisher","first-page":"1946","DOI":"10.2215\/CJN.02400310","article-title":"Prevalence of CKD in northeastern Italy: results of the INCIPE study and comparison with NHANES","volume":"5","author":"Gambaro","year":"2010","journal-title":"Clin J Am Soc Nephrol"},{"key":"2024112623560859700_bib12","doi-asserted-by":"publisher","first-page":"319","DOI":"10.1681\/ASN.V112319","article-title":"Effect of gender on the progression of nondiabetic renal disease: a meta-analysis","volume":"11","author":"Neugarten","year":"2000","journal-title":"J Am Soc Nephrol"},{"key":"2024112623560859700_bib13","doi-asserted-by":"publisher","first-page":"2047","DOI":"10.1093\/ndt\/gfg317","article-title":"The rate of progression of renal disease may not be slower in women compared with men: a patient-level meta-analysis","volume":"18","author":"Jafar","year":"2003","journal-title":"Nephrol Dial Transplant"},{"key":"2024112623560859700_bib14","doi-asserted-by":"publisher","first-page":"2721","DOI":"10.1681\/ASN.2016090986","article-title":"Sex differences in hospitalizations with maintenance hemodialysis","volume":"28","author":"Adams","year":"2017","journal-title":"J Am Soc Nephrol"},{"key":"2024112623560859700_bib15","doi-asserted-by":"publisher","first-page":"413","DOI":"10.1053\/j.ajkd.2012.10.012","article-title":"Estimating the total incidence of kidney failure in Australia including individuals who are not treated by dialysis or transplantation","volume":"61","author":"Sparke","year":"2013","journal-title":"Am J Kidney Dis"},{"key":"2024112623560859700_bib16","doi-asserted-by":"publisher","first-page":"153","DOI":"10.1016\/j.semnephrol.2022.04.006","article-title":"Sex-based differences in risk factors and complications of chronic kidney disease","volume":"42","author":"Wyld","year":"2022","journal-title":"Semin Nephrol"},{"key":"2024112623560859700_bib17","doi-asserted-by":"publisher","first-page":"1157","DOI":"10.1161\/CIRCULATIONAHA.120.050686","article-title":"cardiovascular disease in chronic kidney disease: pathophysiological insights and therapeutic options","volume":"143","author":"Jankowski","year":"2021","journal-title":"Circulation"},{"key":"2024112623560859700_bib18","doi-asserted-by":"publisher","first-page":"330","DOI":"10.1681\/ASN.V112330","article-title":"Race is a major determinant of secondary hyperparathyroidism in uremic patients","volume":"11","author":"Gupta","year":"2000","journal-title":"J Am Soc Nephrol"},{"key":"2024112623560859700_bib19","doi-asserted-by":"publisher","first-page":"1401","DOI":"10.1001\/archinte.162.12.1401","article-title":"Association of kidney function with anaemia: the Third National Health and Nutrition Examination Survey (1988-1994)","volume":"162","author":"Astor","year":"2002","journal-title":"Arch Intern Med"},{"key":"2024112623560859700_bib20","article-title":"Centers for Disease Control and Prevention: National Health and Nutrition Examination Survey","author":"National Center for Health Statistics"},{"key":"2024112623560859700_bib21","volume-title":"Continuous NHANES Public-use Linked Mortality Files","author":"National Center for Health Statistics Division of Analysis and 537 Epidemiology","year":"2019"},{"key":"2024112623560859700_bib22","doi-asserted-by":"publisher","first-page":"268","DOI":"10.1053\/j.ajkd.2021.08.003","article-title":"A Unifying approach for GFR estimation: recommendations of the NKF-ASN Task Force on Reassessing the Inclusion of Race in Diagnosing Kidney Disease","volume":"79","author":"Delgado","year":"2022","journal-title":"Am J Kidney Dis"},{"key":"2024112623560859700_bib23","first-page":"279","article-title":"KDIGO Clinical Practice Guideline for Anaemia in Chronic Kidney Disease","volume":"2","author":"Kidney Disease: Improving Global Outcomes (KDIGO) Anaemia Work Group","year":"2012","journal-title":"Kidney Int"},{"key":"2024112623560859700_bib24","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.kisu.2017.04.001","article-title":"KDIGO 2017 Clinical Practice Guideline Update for the Diagnosis, Evaluation, Prevention, and Treatment of Chronic Kidney Disease\u2013Mineral and Bone Disorder (CKD-MBD)","volume":"7","author":"Kidney Disease: Improving Global Outcomes (KDIGO) CKD-MBD Update Work Group","year":"2017","journal-title":"Kidney Int Suppl"},{"key":"2024112623560859700_bib25","first-page":"1","article-title":"KDIGO 2012 Clinical Practice Guideline for the Evaluation and Management of Chronic Kidney Disease","volume":"3","author":"Kidney Disease: Improving Global Outcomes (KDIGO) CKD Work Group","year":"2013","journal-title":"Kidney Int"},{"key":"2024112623560859700_bib26","doi-asserted-by":"crossref","first-page":"S1","DOI":"10.1016\/j.kint.2020.11.003","article-title":"KDIGO 2021 Clinical Practice Guideline for the Management of Blood Pressure in Chronic Kidney Disease","volume":"99","author":"Kidney Disease: Improving Global Outcomes (KDIGO) Blood Pressure Work Group","year":"2021","journal-title":"Kidney Int"},{"key":"2024112623560859700_bib27","doi-asserted-by":"publisher","first-page":"1306","DOI":"10.1038\/ki.2011.280","article-title":"Higher estimated glomerular filtration rates may be associated with increased risk of adverse outcomes, especially with concomitant proteinuria","volume":"80","author":"Tonelli","year":"2011","journal-title":"Kidney Int"},{"key":"2024112623560859700_bib28","doi-asserted-by":"publisher","first-page":"608","DOI":"10.34067\/KID.0006802021","article-title":"Hyperkalemia and metabolic acidosis occur at a higher eGFR in sickle cell disease","volume":"3","author":"Saraf","year":"2022","journal-title":"Kidney360"},{"key":"2024112623560859700_bib29","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1186\/s12882-020-1689-z","article-title":"Prevalence of chronic kidney disease in the Lazio region, Italy: a classification algorithm based on health information systems","volume":"21","author":"Marino","year":"2020","journal-title":"BMC Nephrol"},{"key":"2024112623560859700_bib30","doi-asserted-by":"publisher","first-page":"1305","DOI":"10.1001\/archinte.1988.00380060069016","article-title":"Age, sex, and race inequality in renal transplantation","volume":"148","author":"Kjellstrand","year":"1988","journal-title":"Arch Intern Med"},{"key":"2024112623560859700_bib31","doi-asserted-by":"publisher","first-page":"1440","DOI":"10.1681\/ASN.2004080639","article-title":"Race, gender, and incident dialysis patients\u2019 reported health status and quality of life","volume":"16","author":"Kutner","year":"2005","journal-title":"J Am Soc Nephrol"},{"key":"2024112623560859700_bib32","doi-asserted-by":"publisher","first-page":"f324","DOI":"10.1136\/bmj.f324","article-title":"Associations of estimated glomerular filtration rate and albuminuria with mortality and renal failure by sex: a meta-analysis","volume":"346","author":"Nitsch","year":"2013","journal-title":"BMJ"},{"key":"2024112623560859700_bib33","doi-asserted-by":"publisher","first-page":"2758","DOI":"10.1681\/ASN.2007040422","article-title":"Age affects outcomes in chronic kidney disease","volume":"18","author":"O'Hare","year":"2007","journal-title":"J Am Soc Nephrol"},{"key":"2024112623560859700_bib34","doi-asserted-by":"publisher","first-page":"863","DOI":"10.1053\/j.ajkd.2005.07.040","article-title":"The natural history of chronic renal failure: results from an unselected, population-based, inception cohort in Sweden","volume":"46","author":"Evans","year":"2005","journal-title":"Am J Kidney Dis"},{"key":"2024112623560859700_bib35","doi-asserted-by":"publisher","first-page":"375","DOI":"10.1038\/sj.ki.5000058","article-title":"The progression of chronic kidney disease: a 10-year population-based study of the effects of gender and age","volume":"69","author":"Eriksen","year":"2006","journal-title":"Kidney Int"},{"key":"2024112623560859700_bib36","doi-asserted-by":"publisher","first-page":"464","DOI":"10.1038\/sj.ki.5002328","article-title":"Gender-specific effects of endogenous testosterone: female alpha-estrogen receptor-deficient C57Bl\/6J mice develop glomerulosclerosis","volume":"72","author":"Elliot","year":"2007","journal-title":"Kidney Int"},{"key":"2024112623560859700_bib37","doi-asserted-by":"publisher","first-page":"1729","DOI":"10.1111\/j.1523-1755.2005.00589.x","article-title":"Gender hormones and the progression of experimental polycystic kidney disease","volume":"68","author":"Stringer","year":"2005","journal-title":"Kidney Int"},{"key":"2024112623560859700_bib38","doi-asserted-by":"publisher","first-page":"528","DOI":"10.1016\/j.amjmed.2008.11.013","article-title":"Adherence to healthy lifestyle habits in US adults, 1988-2006","volume":"122","author":"King","year":"2009","journal-title":"Am J Med"},{"key":"2024112623560859700_bib39","doi-asserted-by":"publisher","first-page":"1631","DOI":"10.1681\/ASN.2011111078","article-title":"Mechanisms of anaemia in CKD","volume":"23","author":"Babitt","year":"2012","journal-title":"J Am Soc Nephrol"},{"key":"2024112623560859700_bib40","doi-asserted-by":"publisher","first-page":"S453","DOI":"10.1093\/cid\/cis247","article-title":"Sex-based differences in food consumption: Foodborne Diseases Active Surveillance Network (FoodNet) Population Survey, 2006-2007","volume":"54","author":"Shiferaw","year":"2012","journal-title":"Clin Infect Dis"},{"key":"2024112623560859700_bib41","doi-asserted-by":"publisher","first-page":"684","DOI":"10.1038\/sj.ijo.0802277","article-title":"Dietary intake, eating behavior, and physical activity-related determinants of high body mass index in rural communities in Wyoming, Montana, and Idaho","volume":"27","author":"Liebman","year":"2003","journal-title":"Int J Obes"},{"key":"2024112623560859700_bib42","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1159\/000505501","article-title":"Is there a gender difference in clinical presentation of renal hyperparathyroidism and outcome after parathyroidectomy?","volume":"36","author":"Bures","year":"2020","journal-title":"Visc Med"},{"key":"2024112623560859700_bib43","doi-asserted-by":"publisher","first-page":"115885","DOI":"10.1016\/j.bone.2021.115885","article-title":"Age and sex effects on FGF23-mediated response to mild phosphate challenge","volume":"146","author":"Tippen","year":"2021","journal-title":"Bone"},{"key":"2024112623560859700_bib44","doi-asserted-by":"publisher","first-page":"c67","DOI":"10.1159\/000151720","article-title":"Mortality at low and high estimated glomerular filtration rate values: a \u2018U\u2019 shaped curve","volume":"110","author":"Cox","year":"2008","journal-title":"Nephron Clin Pract"},{"key":"2024112623560859700_bib45","first-page":"713","article-title":"Cardiovascular disease in patients with chronic kidney disease","volume":"5","author":"Wright","year":"2009","journal-title":"Vasc Health Risk Manag"},{"key":"2024112623560859700_bib46","doi-asserted-by":"publisher","first-page":"1165","DOI":"10.1161\/01.CIR.99.9.1165","article-title":"Sex, age, cardiovascular risk factors, and coronary heart disease: a prospective follow-up study of 14 786 middle-aged men and women in Finland","volume":"99","author":"Jousilahti","year":"1999","journal-title":"Circulation"},{"key":"2024112623560859700_bib47","doi-asserted-by":"publisher","first-page":"383","DOI":"10.1016\/0002-8703(86)90155-9","article-title":"Patterns of coronary heart disease morbidity and mortality in the sexes: a 26-year follow-up of the Framingham population","volume":"111","author":"Lerner","year":"1986","journal-title":"Am Heart J"},{"key":"2024112623560859700_bib48","doi-asserted-by":"publisher","first-page":"F365","DOI":"10.1152\/ajprenal.2001.280.3.F365","article-title":"Estrogen-induced cardiorenal protection: potential cellular, biochemical, and molecular mechanisms","volume":"280","author":"Dubey","year":"2001","journal-title":"Am J Physiol Renal Physiol"},{"key":"2024112623560859700_bib49","doi-asserted-by":"publisher","first-page":"1787","DOI":"10.1093\/ndt\/gfw084","article-title":"Sex hormones in women with kidney disease","volume":"31","author":"Ahmed","year":"2016","journal-title":"Nephrol Dial Transplant"},{"key":"2024112623560859700_bib50","doi-asserted-by":"publisher","first-page":"241","DOI":"10.1159\/000497446","article-title":"Temporal trends in incident mortality in dialysis patients: focus on sex and racial disparities","volume":"49","author":"Shah","year":"2019","journal-title":"Am J Nephrol"},{"key":"2024112623560859700_bib51","doi-asserted-by":"publisher","first-page":"200","DOI":"10.1053\/j.ajkd.2021.01.020","article-title":"Sex differences in cardiovascular outcomes in CKD: findings from the CRIC study","volume":"78","author":"Toth-Manikowski","year":"2021","journal-title":"Am J Kidney Dis"},{"key":"2024112623560859700_bib52","doi-asserted-by":"publisher","first-page":"1057","DOI":"10.1016\/j.jacc.2009.09.065","article-title":"Sex-related differences in myocardial remodeling","volume":"55","author":"Piro","year":"2010","journal-title":"J Am Coll Cardiol"}],"container-title":["Nephrology Dialysis Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/ndt\/advance-article-pdf\/doi\/10.1093\/ndt\/gfae087\/57447475\/gfae087.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ndt\/article-pdf\/39\/12\/2005\/60817546\/gfae087.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ndt\/article-pdf\/39\/12\/2005\/60817546\/gfae087.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,26]],"date-time":"2024-11-26T23:56:15Z","timestamp":1732665375000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ndt\/article\/39\/12\/2005\/7649362"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4,17]]},"references-count":52,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2024,4,17]]},"published-print":{"date-parts":[[2024,11,27]]}},"URL":"https:\/\/doi.org\/10.1093\/ndt\/gfae087","relation":{},"ISSN":["0931-0509","1460-2385"],"issn-type":[{"value":"0931-0509","type":"print"},{"value":"1460-2385","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2024,12]]},"published":{"date-parts":[[2024,4,17]]}}}