{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T05:02:58Z","timestamp":1792213378723,"version":"4.4.0"},"reference-count":65,"publisher":"Oxford University Press (OUP)","issue":"10","license":[{"start":{"date-parts":[[2024,7,15]],"date-time":"2024-07-15T00:00:00Z","timestamp":1721001600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,9,27]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n               <jats:p>Hyponatraemia is the most common electrolyte disorder in hospital patients associated with increased morbidity, mortality, hospital stay and financial burden. The speed of a correction with 3% sodium chloride as a 100- to 150-ml intravenous bolus or continuous infusion depends on the severity and persistence of the symptoms and needs frequent biochemical monitoring. The rapid intermittent administration of hypertonic saline is preferred for treatment of symptomatic hyponatraemia. In asymptomatic mild hyponatraemia, an adequate solute intake with an initial fluid restriction (FR) of 500\u00a0ml\/day adjusted according to the serum sodium (sNa) levels is preferred. Almost half of the syndrome of inappropriate antidiuretic hormone (SIADH) patients do not respond to FR as first-line therapy. At present, urea and tolvaptan are considered the most effective second-line therapies in SIADH. However, the evidence for guidance on the choice of second-line therapy of hypotonic hyponatraemia is lacking. Oral urea is considered to be a very effective and safe treatment. Mild and asymptomatic hyponatraemia is treated with adequate solute intake (salt and protein) and initial FR with adjustments based on sNa levels. Specific treatment with vaptans may be considered in either euvolaemic or hypervolaemic patients with high ADH activity. In order to ensure optimal patient outcome, close monitoring and readiness for administration of either hypotonic fluids or desmopressin may be crucial in the decision-making process for specific treatment and eventual overcorrection consequences. According to the guidelines, gradual correction and clinical evaluation is preferable over rapid normalization of sNa towards the laboratory reference ranges.<\/jats:p>","DOI":"10.1093\/ndt\/gfae162","type":"journal-article","created":{"date-parts":[[2024,7,15]],"date-time":"2024-07-15T23:21:58Z","timestamp":1721085718000},"page":"1583-1592","source":"Crossref","is-referenced-by-count":39,"title":["Hyponatraemia\u2014treatment standard 2024"],"prefix":"10.1093","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5628-2500","authenticated-orcid":false,"given":"Goce","family":"Spasovski","sequence":"first","affiliation":[{"name":"Department of Nephrology, University of Skopje , Sts. Cyril and Methodius, Skopje, N. Macedonia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2024,7,15]]},"reference":[{"key":"2024102212502653700_bib1","doi-asserted-by":"publisher","first-page":"139","DOI":"10.1111\/j.1399-6576.2010.02311.x","article-title":"Initial approach to the hyponatremic patient","volume":"55","author":"Overgaard-Steensen","year":"2011","journal-title":"Acta Anaesthesiol Scand"},{"key":"2024102212502653700_bib2","doi-asserted-by":"publisher","first-page":"ITC1","DOI":"10.7326\/AITC201508040","article-title":"In the clinic: hyponatremia","volume":"163","author":"Henry","year":"2015","journal-title":"Ann Intern Med"},{"key":"2024102212502653700_bib3","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1159\/000493234","article-title":"Etiology and epidemiology of hyponatremia","volume":"52","author":"Burst","year":"2019","journal-title":"Front Horm Res"},{"key":"2024102212502653700_bib4","doi-asserted-by":"publisher","first-page":"1423","DOI":"10.1210\/jc.2011-3201","article-title":"Clinical review: disorders of water homeostasis in neurosurgical patients","volume":"97","author":"Hannon","year":"2012","journal-title":"J Clin Endocrinol Metab"},{"key":"2024102212502653700_bib5","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1007\/s11897-016-0295-7","article-title":"Pharmacologic approaches to electrolyte abnormalities in heart failure","volume":"13","author":"Grodin","year":"2016","journal-title":"Curr Heart Fail Rep"},{"key":"2024102212502653700_bib6","doi-asserted-by":"publisher","first-page":"2790","DOI":"10.3390\/jcm9092790","article-title":"Are further interventions needed to prevent and manage hospital-acquired hyponatraemia? A nationwide cross-sectional survey of IV fluid prescribing practices","volume":"9","author":"Sindahl","year":"2020","journal-title":"J Clin Med"},{"key":"2024102212502653700_bib7","doi-asserted-by":"publisher","first-page":"357","DOI":"10.1016\/j.nefro.2017.03.001","article-title":"Guidelines on hyponatremia that not always guide","volume":"37","author":"Alc\u00e1zar","year":"2017","journal-title":"Nefrolog\u00eda"},{"key":"2024102212502653700_bib8","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s12916-014-0231-1","article-title":"Diagnosis and treatment of hyponatremia: systematic review of clinical practice","volume":"12","author":"Nagler","year":"2014","journal-title":"BMC Med"},{"key":"2024102212502653700_bib9","doi-asserted-by":"publisher","first-page":"i1","DOI":"10.1093\/ndt\/gfu040","article-title":"Clinical practice guideline on diagnosis and treatment of hyponatraemia","volume":"29","author":"Spasovski","year":"2014","journal-title":"Nephrol Dial Transplant"},{"issue":"10 Suppl 1","key":"2024102212502653700_bib10","doi-asserted-by":"publisher","first-page":"S1","DOI":"10.1016\/j.amjmed.2013.07.006","article-title":"Diagnosis, evaluation, and treatment of hyponatremia: expert panel recommendations","volume":"126","author":"Verbalis","year":"2013","journal-title":"Am J Med"},{"key":"2024102212502653700_bib11","doi-asserted-by":"publisher","first-page":"1430","DOI":"10.1373\/clinchem.2015.242602","article-title":"Reference change values for sodium are ignored by the American and European treatment guidelines for hyponatremia","volume":"61","author":"Tormey","year":"2015","journal-title":"Clin Chem"},{"key":"2024102212502653700_bib12","doi-asserted-by":"publisher","first-page":"E281","DOI":"10.1503\/cmaj.120887","article-title":"Management of hyponatremia","volume":"186","author":"Lee","year":"2014","journal-title":"CMAJ"},{"key":"2024102212502653700_bib13","doi-asserted-by":"publisher","first-page":"263","DOI":"10.7861\/clinmedicine.17-3-263","article-title":"Hyponatraemia\u2014presentations and management","volume":"17","author":"Dineen","year":"2017","journal-title":"Clin Med"},{"key":"2024102212502653700_bib14","doi-asserted-by":"publisher","first-page":"467","DOI":"10.1016\/j.jpeds.2006.11.062","article-title":"Preventing a drop in effective plasma osmolality to minimize the likelihood of cerebral edema during treatment of children with diabetic ketoacidosis","volume":"150","author":"Hoorn","year":"2007","journal-title":"J Pediatr"},{"key":"2024102212502653700_bib15","doi-asserted-by":"publisher","first-page":"126","DOI":"10.1097\/MPA.0000000000001192","article-title":"Pseudohyponatremia in hypertriglyceridemia-induced acute pancreatitis: a tool for diagnosis rather than merely a laboratory error?","volume":"48","author":"Wang","year":"2019","journal-title":"Pancreas"},{"key":"2024102212502653700_bib16","doi-asserted-by":"publisher","first-page":"1340","DOI":"10.1681\/ASN.2016101139","article-title":"Diagnosis and treatment of hyponatremia: compilation of the guidelines","volume":"28","author":"Hoorn","year":"2017","journal-title":"J Am Soc Nephrol"},{"key":"2024102212502653700_bib17","doi-asserted-by":"publisher","first-page":"20","DOI":"10.7326\/0003-4819-126-1-199701010-00003","article-title":"Postoperative hyponatremia despite near-isotonic saline infusion: a phenomenon of desalination","volume":"126","author":"Steele","year":"1997","journal-title":"Ann Intern Med"},{"key":"2024102212502653700_bib18","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1016\/j.ejim.2015.11.022","article-title":"Ten common pitfalls in the evaluation of patients with hyponatremia","volume":"29","author":"Filippatos","year":"2016","journal-title":"Eur J Intern Med"},{"key":"2024102212502653700_bib19","doi-asserted-by":"publisher","first-page":"493","DOI":"10.1097\/MNH.0b013e32833bfa64","article-title":"Treatment of hyponatremia","volume":"19","author":"Sterns","year":"2010","journal-title":"Curr Opin Nephrol Hypertens"},{"key":"2024102212502653700_bib20","doi-asserted-by":"publisher","first-page":"435","DOI":"10.1053\/j.ajkd.2014.09.021","article-title":"Treatment of hyponatremic encephalopathy with a 3% sodium chloride protocol: a case series","volume":"65","author":"Ayus","year":"2015","journal-title":"Am J Kidney Dis"},{"key":"2024102212502653700_bib21","doi-asserted-by":"publisher","first-page":"79","DOI":"10.7861\/clinmedicine.10-1-79","article-title":"Serum sodium disorders: safe management","volume":"10","author":"Wakil","year":"2010","journal-title":"Clin Med"},{"key":"2024102212502653700_bib22","doi-asserted-by":"crossref","first-page":"1880","DOI":"10.1210\/jc.2015-4228","article-title":"Association between hyponatremia, osteoporosis and fracture: a systematic review and meta-analysis","volume":"101","author":"Sikarin","year":"2016","journal-title":"J Clin Endocrinol Metab"},{"key":"2024102212502653700_bib23","doi-asserted-by":"publisher","first-page":"322","DOI":"10.1093\/ejendo\/lvad028","article-title":"Overcorrection and undercorrection with fixed dosing of bolus hypertonic saline for symptomatic hyponatremia","volume":"188","author":"Pelouto","year":"2023","journal-title":"Eur J Endocrinol"},{"key":"2024102212502653700_bib24","doi-asserted-by":"publisher","first-page":"647","DOI":"10.1530\/EJE-20-1207","article-title":"Treatment of symptomatic hyponatremia with hypertonic saline: a real-life observational study","volume":"184","author":"Chifu","year":"2021","journal-title":"Eur J Endocrinol"},{"key":"2024102212502653700_bib25","doi-asserted-by":"publisher","first-page":"516","DOI":"10.1080\/00325481.2016.1186488","article-title":"Ten pitfalls in the proper management of patients with hyponatremia","volume":"128","author":"Filippatos","year":"2016","journal-title":"Postgrad Med"},{"key":"2024102212502653700_bib26","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1001\/jamainternmed.2020.5519","article-title":"Risk of overcorrection in rapid intermittent bolus vs slow continuous infusion therapies of hypertonic saline for patients with symptomatic hyponatremia: the SALSA randomized clinical trial","volume":"181","author":"Baek","year":"2021","journal-title":"JAMA Intern Med"},{"key":"2024102212502653700_bib27","doi-asserted-by":"publisher","first-page":"742","DOI":"10.1053\/j.ajkd.2009.12.024","article-title":"A patient with severe hyponatremia and hypokalemia: osmotic demyelination following potassium repletion","volume":"55","author":"Berl","year":"2010","journal-title":"Am J Kidney Dis"},{"key":"2024102212502653700_bib28","doi-asserted-by":"publisher","first-page":"424","DOI":"10.1097\/MNH.0000000000000528","article-title":"Recent developments in the management of acute and chronic hyponatremia","volume":"28","author":"Hoorn","year":"2019","journal-title":"Curr Opin Nephrol Hypertens"},{"key":"2024102212502653700_bib29","first-page":"93","article-title":"Hypovolemic hyponatremia","volume-title":"Front Horm Res","author":"Mohottige","year":"2019"},{"key":"2024102212502653700_bib30","doi-asserted-by":"publisher","first-page":"3567","DOI":"10.3390\/jcm9113567","article-title":"The effect of the dose of isotonic saline on the correction of serum sodium in the treatment of hypovolemic hyponatremia","volume":"9","author":"Ruiz-S\u00e1nchez","year":"2020","journal-title":"J Clin Med"},{"key":"2024102212502653700_bib31","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1159\/000493242","article-title":"Hypervolemic hyponatremia in heart failure","volume":"52","author":"Davila","year":"2019","journal-title":"Front Horm Res"},{"key":"2024102212502653700_bib32","doi-asserted-by":"publisher","first-page":"1775","DOI":"10.14309\/ajg.0000000000000786","article-title":"Hyponatremia in cirrhosis: an update","volume":"115","author":"Alukal","year":"2020","journal-title":"Am J Gastroenterol"},{"key":"2024102212502653700_bib33","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1136\/bmj.285.6335.89","article-title":"Inappropriate secretion of antidiuretic hormone treated with frusemide","volume":"285","author":"Decaux","year":"1982","journal-title":"BMJ"},{"key":"2024102212502653700_bib34","doi-asserted-by":"publisher","first-page":"1319","DOI":"10.1001\/jama.297.12.1319","article-title":"Effects of oral tolvaptan in patients hospitalized for worsening heart failure: the EVEREST Outcome Trial","volume":"297","author":"Konstam","year":"2007","journal-title":"JAMA"},{"key":"2024102212502653700_bib35","doi-asserted-by":"publisher","first-page":"2537","DOI":"10.1111\/ajt.14317","article-title":"Prevention of the osmotic demyelination syndrome after liver transplantation: a multidisciplinary perspective","volume":"17","author":"Crismale","year":"2017","journal-title":"Am J Transplant"},{"key":"2024102212502653700_bib36","doi-asserted-by":"publisher","first-page":"1627","DOI":"10.2215\/CJN.04020318","article-title":"Urea for the treatment of hyponatremia","volume":"13","author":"Rondon-Berrios","year":"2018","journal-title":"Clin J Am Soc Nephrol"},{"key":"2024102212502653700_bib37","doi-asserted-by":"publisher","first-page":"212","DOI":"10.1159\/000503773","article-title":"Urea for chronic hyponatremia","volume-title":"Blood Purif","author":"Rondon-Berrios","year":"2020"},{"key":"2024102212502653700_bib38","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1159\/000493238","article-title":"Euvolemic hyponatremia secondary to the syndrome of inappropriate antidiuresis","volume":"52","author":"Verbalis","year":"2019","journal-title":"Front Horm Res"},{"key":"2024102212502653700_bib39","doi-asserted-by":"publisher","first-page":"167","DOI":"10.1038\/ki.2015.4","article-title":"Current treatment practice and outcomes. Report of the hyponatremia registry","volume":"88","author":"Greenberg","year":"2015","journal-title":"Kidney Int"},{"key":"2024102212502653700_bib40","doi-asserted-by":"publisher","first-page":"e4360","DOI":"10.1210\/clinem\/dgaa619","article-title":"Fluid restriction therapy for chronic SIAD; results of a prospective randomized controlled trial","volume":"105","author":"Garrahy","year":"2020","journal-title":"J Clin Endocrinol Metab"},{"key":"2024102212502653700_bib41","first-page":"AEP434","article-title":"Drinking only when thirsty or when eating solids can normalize serum sodium levels in most patients with SIADH and a high fluid intake, regardless of urine osmolarity","volume":"73","author":"Pazos","year":"2021","journal-title":"Endocr Abstr"},{"key":"2024102212502653700_bib42","doi-asserted-by":"publisher","first-page":"489","DOI":"10.1093\/qjmed\/hcx036","article-title":"Predictors of failure to respond to fluid restriction in SIAD in clinical practice; time to re-evaluate clinical guidelines?","volume":"110","author":"Cuesta","year":"2017","journal-title":"QJM"},{"key":"2024102212502653700_bib43","doi-asserted-by":"publisher","first-page":"203","DOI":"10.1053\/j.ajkd.2019.11.012","article-title":"Efficacy of furosemide, oral sodium chloride, and fluid restriction for treatment of syndrome of inappropriate antidiuresis (SIAD): an open-label randomized controlled study (the EFFUSE-FLUID Trial)","volume":"76","author":"Krisanapan","year":"2020","journal-title":"Am J Kidney Dis"},{"key":"2024102212502653700_bib44","doi-asserted-by":"publisher","first-page":"141","DOI":"10.3389\/fmed.2017.00141","article-title":"Vasopressin receptor antagonists in hyponatremia: uses and misuses","volume":"4","author":"Rondon-Berrios","year":"2017","journal-title":"Front Med"},{"key":"2024102212502653700_bib45","doi-asserted-by":"publisher","first-page":"183","DOI":"10.3390\/ijms21010183","article-title":"Lixivaptan, a new generation diuretic, counteracts vasopressin-induced aquaporin-2 trafficking and function in renal collecting duct cells","volume":"21","author":"Di Mise","year":"2019","journal-title":"Int J Mol Sci"},{"key":"2024102212502653700_bib46","doi-asserted-by":"publisher","first-page":"761","DOI":"10.1111\/cen.13315","article-title":"A systematic review of known interventions for the treatment of chronic nonhypovolaemic hypotonic hyponatraemia and a meta-analysis of the vaptans","volume":"86","author":"Bhandari","year":"2017","journal-title":"Clin Endocrinol (Oxf)"},{"key":"2024102212502653700_bib47","doi-asserted-by":"publisher","first-page":"924","DOI":"10.3350\/cmh.2023.0090","article-title":"Evidence-based hyponatremia management in liver disease","volume":"29","author":"Ryu","year":"2023","journal-title":"Clin Mol Hepatol"},{"key":"2024102212502653700_bib48","doi-asserted-by":"publisher","first-page":"280","DOI":"10.1001\/jama.2022.11176","article-title":"Diagnosis and management of hyponatremia: a review","volume":"328","author":"Adrogu\u00e9","year":"2022","journal-title":"JAMA"},{"key":"2024102212502653700_bib49","doi-asserted-by":"publisher","first-page":"842","DOI":"10.1111\/cen.13966","article-title":"Urea in cancer patients with chronic SIAD-induced hyponatremia: old drug, new evidence","volume":"90","author":"Nervo","year":"2019","journal-title":"Clin Endocrinol (Oxf)"},{"key":"2024102212502653700_bib50","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1016\/j.ejim.2017.09.024","article-title":"Mild water restriction with or without urea for the long- term treatment of syndrome of inappropriate antidiuretic hormone secretion (SIADH): can urine osmolality help the choice?","volume":"48","author":"Decaux","year":"2018","journal-title":"Eur J Intern Med"},{"key":"2024102212502653700_bib51","doi-asserted-by":"publisher","first-page":"615","DOI":"10.1681\/ASN.2019090944","article-title":"A randomized trial of empagliflozin to increase plasma sodium levels in patients with the syndrome of inappropriate antidiuresis","volume":"31","author":"Refardt","year":"2020","journal-title":"J Am Soc Nephrol"},{"key":"2024102212502653700_bib52","doi-asserted-by":"publisher","first-page":"819","DOI":"10.1210\/endrev\/bnad010","article-title":"Syndrome of inappropriate antidiuresis: from pathophysiology to management","volume":"44","author":"Warren","year":"2023","journal-title":"Endocr Rev"},{"key":"2024102212502653700_bib53","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnesp.2023.10.037","article-title":"Palatability of two different formulations of urea for the treatment of hyponatremia: A double-blind, randomized, cross-over study","volume":"58","author":"Colombo","year":"2023","journal-title":"Clin Nutr ESPEN"},{"key":"2024102212502653700_bib54","doi-asserted-by":"publisher","first-page":"630","DOI":"10.1111\/cen.13930","article-title":"Urea treatment in fluid restriction-refractory hyponatraemia","volume":"90","author":"Lockett","year":"2019","journal-title":"Clin Endocrinol (Oxf)"},{"key":"2024102212502653700_bib55","doi-asserted-by":"publisher","first-page":"742","DOI":"10.2215\/CJN.06990711","article-title":"Efficacy and tolerance of urea compared with vaptans for long-term treatment of patients with SIADH","volume":"7","author":"Soupart","year":"2012","journal-title":"Clin J Am Soc Nephrol"},{"key":"2024102212502653700_bib56","doi-asserted-by":"publisher","first-page":"335","DOI":"10.1186\/s13063-022-06237-5","article-title":"Tolvaptan versus fluid restriction in acutely hospitalised patients with moderate-profound hyponatraemia (TVFR-HypoNa): design and implementation of an open-label randomised trial","volume":"23","author":"Warren","year":"2022","journal-title":"Trials"},{"key":"2024102212502653700_bib57","doi-asserted-by":"publisher","first-page":"322","DOI":"10.1681\/ASN.2022050623","article-title":"Treatment effect of the SGLT2 inhibitor empagliflozin on chronic syndrome of inappropriate antidiuresis: results of a randomized, double-blind, placebo-controlled, crossover trial","volume":"34","author":"Refardt","year":"2023","journal-title":"J Am Soc Nephrol"},{"key":"2024102212502653700_bib58","article-title":"Effects of the SGLT2 inhibitor empagliflozin in patients with euvolemic and hypervolemic hyponatremia","author":"University Hospital, Basel, Switzerland"},{"key":"2024102212502653700_bib59","doi-asserted-by":"publisher","first-page":"539","DOI":"10.1007\/s12020-016-1161-9","article-title":"Improving care and outcomes of inpatients with syndrome of inappropriate antidiuresis (SIAD): a prospective intervention study of intensive endocrine input vs. routine care","volume":"55","author":"Tzoulis","year":"2017","journal-title":"Endocrine"},{"key":"2024102212502653700_bib60","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1530\/EJE-20-0577","article-title":"Active management of severe hyponatraemia is associated with improved mortality","volume":"184","author":"Garrahy","year":"2021","journal-title":"Eur J Endocrinol"},{"key":"2024102212502653700_bib61","doi-asserted-by":"publisher","first-page":"729545","DOI":"10.3389\/fmed.2021.729545","article-title":"Hyponatremia intervention trial (HIT): study protocol of a randomized, controlled, parallel-group trial with blinded outcome assessment","volume":"8","author":"Refardt","year":"2021","journal-title":"Front Med"},{"key":"2024102212502653700_bib62","first-page":"80","article-title":"Epidemiology of hyponatraemia among elderly patients with lower respiratory tract infection","volume":"68","author":"Akash","year":"2020","journal-title":"J Assoc Physicians India"},{"key":"2024102212502653700_bib63","doi-asserted-by":"publisher","first-page":"823","DOI":"10.1016\/j.amjmed.2016.03.007","article-title":"The economic burden of hyponatremia: systematic review and meta-analysis","volume":"129","author":"Corona","year":"2016","journal-title":"Am J Med"},{"key":"2024102212502653700_bib64","doi-asserted-by":"publisher","first-page":"282","DOI":"10.2215\/CJN.04880419","article-title":"Therapeutic relowering of plasma sodium after overly rapid correction of hyponatremia: what is the evidence?","volume":"15","author":"Rondon-Berrios","year":"2020","journal-title":"Clin J Am Soc Nephrol"},{"key":"2024102212502653700_bib65","doi-asserted-by":"publisher","first-page":"48","DOI":"10.1097\/01.JAA.0000578796.15417.09","article-title":"Managing hyponatremia","volume":"32","author":"Boyle","year":"2019","journal-title":"JAAPA"}],"container-title":["Nephrology Dialysis Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/ndt\/advance-article-pdf\/doi\/10.1093\/ndt\/gfae162\/58815232\/gfae162.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ndt\/article-pdf\/39\/10\/1583\/59959040\/gfae162.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ndt\/article-pdf\/39\/10\/1583\/59959040\/gfae162.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,10,22]],"date-time":"2024-10-22T12:52:26Z","timestamp":1729601546000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ndt\/article\/39\/10\/1583\/7713921"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7,15]]},"references-count":65,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2024,7,15]]},"published-print":{"date-parts":[[2024,9,27]]}},"URL":"https:\/\/doi.org\/10.1093\/ndt\/gfae162","relation":{},"ISSN":["0931-0509","1460-2385"],"issn-type":[{"value":"0931-0509","type":"print"},{"value":"1460-2385","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2024,10]]},"published":{"date-parts":[[2024,7,15]]}}}