{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T18:45:20Z","timestamp":1791830720636,"version":"4.3.4"},"reference-count":37,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2024,9,24]],"date-time":"2024-09-24T00:00:00Z","timestamp":1727136000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,12,20]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n               <jats:p>Chronic kidney disease\u2013mineral and bone disorder (CKD-MBD) contributes substantially to the burden of cardiovascular disease and fractures in patients with CKD. An increasing arsenal of diagnostic tools, including bone turnover markers and bone imaging, is available to support clinicians in the management of CKD-associated osteoporosis. Although not mandatory, a bone biopsy remains useful in the diagnostic workup of complex cases. In this special report, the European Renal Osteodystrophy (EUROD) initiative introduces the concept of a kidney\u2013bone multidisciplinary team (MDT) for the diagnosis and clinical management of challenging cases of CKD-associated osteoporosis. In 2021, the EUROD initiative launched virtual clinical-pathological case conferences to discuss challenging cases of patients with CKD-associated osteoporosis, in whom a bone biopsy was useful in the diagnostic workup. Out of these, we selected four representative cases and asked a kidney\u2013bone MDT consisting of a nephrologist, an endocrinologist and a rheumatologist to provide comments on the diagnostic and therapeutic choices. These cases covered a broad spectrum of CKD-associated osteoporosis, including bone fracture in CKD G5D, post-transplant bone disease, disturbed bone mineralization, severely suppressed bone turnover and severe hyperparathyroidism. Comments from the MDT were, in most cases, complementary to each other and additive to the presented approach in the cases. The MDT approach may thus set the stage for improved diagnostics and tailored therapies in the field of CKD-associated osteoporosis. We demonstrate the clinical utility of a kidney-bone MDT for the management of patients with CKD-MBD and recommend their establishment at local, national, and international levels.<\/jats:p>","DOI":"10.1093\/ndt\/gfae197","type":"journal-article","created":{"date-parts":[[2024,9,24]],"date-time":"2024-09-24T12:52:16Z","timestamp":1727182336000},"page":"48-59","source":"Crossref","is-referenced-by-count":18,"title":["Multidisciplinary team approach for CKD-associated osteoporosis"],"prefix":"10.1093","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4929-7901","authenticated-orcid":false,"given":"Ditte","family":"Hansen","sequence":"first","affiliation":[{"name":"Department of Nephrology, Copenhagen University Hospital \u2013 Herlev , Copenhagen ,","place":["Denmark"]},{"name":"Institute of Clinical Medicine, University of Copenhagen , Copenhagen 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Aarhus University , Aarhus ,","place":["Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1323-5293","authenticated-orcid":false,"given":"Ana Carina","family":"Ferreira","sequence":"additional","affiliation":[{"name":"Department of Nephrology, ULS S\u00e3o Jos\u00e9 Lisbon ,","place":["Portugal"]},{"name":"Universidade Nova de Lisboa- NOVA Medical School-Nephology , Lisbon ,","place":["Portugal"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"An\u00edbal","family":"Ferreira","sequence":"additional","affiliation":[{"name":"Department of Nephrology, ULS S\u00e3o Jos\u00e9 Lisbon ,","place":["Portugal"]},{"name":"Universidade Nova de Lisboa- NOVA Medical School-Nephology , Lisbon ,","place":["Portugal"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renate","family":"de Jongh","sequence":"additional","affiliation":[{"name":"Department of Endocrinology and Metabolism, Amsterdam UMC location Vrije 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