{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,18]],"date-time":"2026-05-18T07:11:34Z","timestamp":1779088294908,"version":"3.51.4"},"reference-count":29,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2025,7,4]],"date-time":"2025-07-04T00:00:00Z","timestamp":1751587200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,12,23]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Chronic kidney disease (CKD) is common in both type 1 and type 2 diabetes and complicated glycemic control due to fluctuating insulin resistance and metabolism. In advanced CKD (stage 4 and stage 5, or estimated glomerular filtration rate &amp;lt;30\u00a0mL\/min\/1.73 m2), reduced kidney clearance of insulin can lower or eliminated insulin needs, but glycemic control remains challenging. This article reviews optimal glycemic targets, monitoring and current therapeutic recommendations for patients with severe CKD or on dialysis, addressing the lack of efficacy data for many antihyperglycemics in this population.<\/jats:p>","DOI":"10.1093\/ndt\/gfaf083","type":"journal-article","created":{"date-parts":[[2025,4,29]],"date-time":"2025-04-29T07:49:17Z","timestamp":1745912957000},"page":"31-41","source":"Crossref","is-referenced-by-count":4,"title":["Treatment of diabetes in patients with advanced chronic kidney disease or kidney failure"],"prefix":"10.1093","volume":"41","author":[{"given":"George","family":"Bonifant","sequence":"first","affiliation":[{"name":"University of Maryland School of Medicine From the Division of Nephrology, Department of Medicine, Zucker School of Medicine at Hofstra\/Northwell Staten Island University Hospital, and The Divisions of Endocrinology, Nutrition and Obesity and Nephrology, Department of Medicine, , Baltimore, MD ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephen N","family":"Davis","sequence":"additional","affiliation":[{"name":"University of Maryland School of Medicine From the Division of Nephrology, Department of Medicine, Zucker School of Medicine at Hofstra\/Northwell Staten Island University Hospital, and The Divisions of Endocrinology, Nutrition and Obesity and Nephrology, Department of Medicine, , Baltimore, MD ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthew R","family":"Weir","sequence":"additional","affiliation":[{"name":"University of Maryland School of Medicine From the Division of Nephrology, Department of Medicine, Zucker School of Medicine at Hofstra\/Northwell Staten Island University Hospital, and The Divisions of Endocrinology, Nutrition and Obesity and Nephrology, Department of Medicine, , Baltimore, MD ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2025,7,4]]},"reference":[{"key":"2025122223470156200_bib1","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1007\/s00125-018-4711-2","article-title":"Global trends in diabetes complications: a review of current evidence","volume":"62","author":"Harding","year":"2019","journal-title":"Diabetologia"},{"key":"2025122223470156200_bib2","doi-asserted-by":"publisher","first-page":"756","DOI":"10.1210\/endrev\/bnaa017","article-title":"Glycemic monitoring and management in advanced chronic kidney disease","volume":"41","author":"Galindo","year":"2020","journal-title":"Endocr Rev"},{"key":"2025122223470156200_bib3","doi-asserted-by":"publisher","first-page":"651","DOI":"10.4239\/wjd.v5.i5.651","article-title":"Diabetes treatment in patients with renal disease: is the landscape clear enough?","volume":"5","author":"Ioannidis","year":"2014","journal-title":"World J Diabetes"},{"key":"2025122223470156200_bib4","doi-asserted-by":"publisher","first-page":"3075","DOI":"10.2337\/dci22-0027","article-title":"Diabetes management in chronic kidney disease: a consensus report by the American Diabetes Association (ADA) and Kidney Disease: Improving Global Outcomes (KDIGO)","volume":"45","author":"de Boer","year":"2022","journal-title":"Diabetes Care"},{"key":"2025122223470156200_bib5","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1186\/s40842-015-0001-9","article-title":"Management of diabetes mellitus in patients with chronic kidney disease","volume":"1","author":"Hahr","year":"2015","journal-title":"Clin Diabetes Endocrinol"},{"key":"2025122223470156200_bib6","doi-asserted-by":"publisher","first-page":"e158","DOI":"10.2337\/dc15-1096","article-title":"Effect of acetaminophen on CGM glucose in an outpatient setting","volume":"38","author":"Maahs","year":"2015","journal-title":"Diabetes Care"},{"key":"2025122223470156200_bib7","doi-asserted-by":"publisher","first-page":"1119","DOI":"10.1210\/clinem\/dgad652","article-title":"Effectiveness of continuous glucose monitoring on metrics of glycemic control in type 2 diabetes mellitus: a systematic review and meta-analysis of randomized controlled trials","volume":"109","author":"Uhl","year":"2024","journal-title":"J Clin Endocrinol Metab"},{"key":"2025122223470156200_bib8","doi-asserted-by":"publisher","first-page":"S126","DOI":"10.2337\/dc24-S007","article-title":"7. 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