{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,9]],"date-time":"2026-02-09T06:15:13Z","timestamp":1770617713931,"version":"3.49.0"},"reference-count":22,"publisher":"Oxford University Press (OUP)","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2005,7,1]]},"DOI":"10.1093\/ndt\/gfh834","type":"journal-article","created":{"date-parts":[[2005,4,26]],"date-time":"2005-04-26T22:58:22Z","timestamp":1114556302000},"page":"1370-1377","source":"Crossref","is-referenced-by-count":107,"title":["1,25-Dihydroxyvitamin D3 but not cinacalcet HCl (Sensipar\u00ae\/Mimpara\u00ae) treatment mediates aortic calcification in a rat model of secondary hyperparathyroidism"],"prefix":"10.1093","volume":"20","author":[{"given":"Charles","family":"Henley","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matt","family":"Colloton","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Russell C.","family":"Cattley","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edward","family":"Shatzen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dwight A.","family":"Towler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Lacey","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Martin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2005,4,26]]},"reference":[{"key":"key\n\t\t\t\t20171011010044_BIB1","doi-asserted-by":"crossref","unstructured":"Chen NX, Moe SM. Vascular calcification in chronic kidney disease. Semin Nephrol2004; 24: 61\u201368","DOI":"10.1053\/j.semnephrol.2003.08.014"},{"key":"key\n\t\t\t\t20171011010044_BIB2","doi-asserted-by":"crossref","unstructured":"Block GA. The impact of calcimimetics on mineral metabolism and secondary hyperparathyroidism in end-stage renal disease. Kidney Int Suppl2003; S131\u2013S136","DOI":"10.1046\/j.1523-1755.64.s87.20.x"},{"key":"key\n\t\t\t\t20171011010044_BIB3","doi-asserted-by":"crossref","unstructured":"Guerin AP, London GM, Marchais SJ, Metivier F. Arterial stiffening and vascular calcifications in end-stage renal disease. Nephrol Dial Transplant2000; 15: 1014\u20131021","DOI":"10.1093\/ndt\/15.7.1014"},{"key":"key\n\t\t\t\t20171011010044_BIB4","doi-asserted-by":"crossref","unstructured":"Vattikuti R, Towler DA. Osteogenic regulation of vascular calcification: an early perspective. Am J Physiol Endocrinol Metab2004; 286: E686\u2013E696","DOI":"10.1152\/ajpendo.00552.2003"},{"key":"key\n\t\t\t\t20171011010044_BIB5","doi-asserted-by":"crossref","unstructured":"Goodman WG. The consequences of uncontrolled secondary hyperparathyroidism and its treatment in chronic kidney disease. Semin Dial2004; 17: 209\u2013216","DOI":"10.1111\/j.0894-0959.2004.17308.x"},{"key":"key\n\t\t\t\t20171011010044_BIB6","doi-asserted-by":"crossref","unstructured":"Martin KJ, Gonzalez EA. Strategies to minimize bone disease in renal failure. Am J Kidney Dis2001; 38: 1430\u20131436","DOI":"10.1053\/ajkd.2001.29283"},{"key":"key\n\t\t\t\t20171011010044_BIB7","doi-asserted-by":"crossref","unstructured":"Brown EM, Gamba G, Riccardi D et al. Cloning and characterization of an extracellular Ca(2+)-sensing receptor from bovine parathyroid. Nature1993; 366: 575\u2013580","DOI":"10.1038\/366575a0"},{"key":"key\n\t\t\t\t20171011010044_BIB8","doi-asserted-by":"crossref","unstructured":"Nemeth EF, Heaton WH, Miller M et al. Pharmacodynamics of the type II calcimimetic compound cinacalcet HCl. J Pharmacol Exp Ther2004; 308: 627\u2013635","DOI":"10.1124\/jpet.103.057273"},{"key":"key\n\t\t\t\t20171011010044_BIB9","doi-asserted-by":"crossref","unstructured":"Block GA, Martin KJ, de Francisco AL et al. Cinacalcet for secondary hyperparathyroidism in patients receiving hemodialysis. N Engl J Med2004; 350: 1516\u20131525","DOI":"10.1056\/NEJMoa031633"},{"key":"key\n\t\t\t\t20171011010044_BIB10","doi-asserted-by":"crossref","unstructured":"Wallin R, Wajih N, Greenwood GT, Sane DC. Arterial calcification: a review of mechanisms, animal models, and the prospects for therapy. Med Res Rev2001; 21: 274\u2013301","DOI":"10.1002\/med.1010"},{"key":"key\n\t\t\t\t20171011010044_BIB11","doi-asserted-by":"crossref","unstructured":"Bailie GR, Johnson CA. Comparative review of the pharmacokinetics of vitamin D analogues. Semin Dial2002; 15: 352\u2013357","DOI":"10.1046\/j.1525-139X.2002.00086.x"},{"key":"key\n\t\t\t\t20171011010044_BIB12","doi-asserted-by":"crossref","unstructured":"Jongen MJ, Bishop JE, Cade C, Norman AW. Effect of dietary calcium, phosphate and vitamin D deprivation on the pharmacokinetics of 1,25-dihydroxyvitamin D3 in the rat. Horm Metab Res1987; 19: 481\u2013485","DOI":"10.1055\/s-2007-1011858"},{"key":"key\n\t\t\t\t20171011010044_BIB13","doi-asserted-by":"crossref","unstructured":"Kissmeyer AM, Binderup L. Calcipotriol (MC 903): pharmacokinetics in rats and biological activities of metabolites. A comparative study with 1,25(OH)2D3. Biochem Pharmacol1991; 41: 1601\u20131606","DOI":"10.1016\/0006-2952(91)90160-7"},{"key":"key\n\t\t\t\t20171011010044_BIB14","doi-asserted-by":"crossref","unstructured":"Goldsmith DJ, Covic A, Sambrook PA, Ackrill P. Vascular calcification in long-term haemodialysis patients in a single unit: a retrospective analysis. Nephron1997; 77: 37\u201343","DOI":"10.1159\/000190244"},{"key":"key\n\t\t\t\t20171011010044_BIB15","doi-asserted-by":"crossref","unstructured":"Kawagishi T, Nishizawa Y, Konishi T et al. High-resolution B-mode ultrasonography in evaluation of atherosclerosis in uremia. Kidney Int1995; 48: 820\u2013826","DOI":"10.1038\/ki.1995.356"},{"key":"key\n\t\t\t\t20171011010044_BIB16","unstructured":"Fox J, Lowe SH, Petty BA, Nemeth EF. NPS R-568: a type II calcimimetic compound that acts on parathyroid cell calcium receptor of rats to reduce plasma levels of parathyroid hormone and calcium. J Pharmacol Exp Ther1999; 290: 473\u2013479"},{"key":"key\n\t\t\t\t20171011010044_BIB17","doi-asserted-by":"crossref","unstructured":"Naveh-Many T, Rahamimov R, Livni N, Silver J. Parathyroid cell proliferation in normal and chronic renal failure rats. The effects of calcium, phosphate, and vitamin D. J Clin Invest1995; 96: 1786\u20131793","DOI":"10.1172\/JCI118224"},{"key":"key\n\t\t\t\t20171011010044_BIB18","doi-asserted-by":"crossref","unstructured":"Moe SM, O'Neill KD, Duan D et al. Medial artery calcification in ESRD patients is associated with deposition of bone matrix proteins. Kidney Int2002; 61: 638\u2013647","DOI":"10.1046\/j.1523-1755.2002.00170.x"},{"key":"key\n\t\t\t\t20171011010044_BIB19","doi-asserted-by":"crossref","unstructured":"Reynolds JL, Joannides AJ, Skepper JN et al. Human vascular smooth muscle cells undergo vesicle-mediated calcification in response to changes in extracellular calcium and phosphate concentrations: a potential mechanism for accelerated vascular calcification in ESRD. J Am Soc Nephrol2004; 15: 2857\u20132867","DOI":"10.1097\/01.ASN.0000141960.01035.28"},{"key":"key\n\t\t\t\t20171011010044_BIB20","doi-asserted-by":"crossref","unstructured":"Jono S, Nishizawa Y, Shioi A, Morii H. Parathyroid hormone-related peptide as a local regulator of vascular calcification. Its inhibitory action on in vitro calcification by bovine vascular smooth muscle cells. Arterioscler Thromb Vasc Biol1997; 17: 1135\u20131142","DOI":"10.1161\/01.ATV.17.6.1135"},{"key":"key\n\t\t\t\t20171011010044_BIB21","doi-asserted-by":"crossref","unstructured":"Jono S, Nishizawa Y, Shioi A, Morii H. 1,25-Dihydroxyvitamin D3 increases in vitro vascular calcification by modulating secretion of endogenous parathyroid hormone-related peptide. Circulation1998; 98: 1302\u20131306","DOI":"10.1161\/01.CIR.98.13.1302"},{"key":"key\n\t\t\t\t20171011010044_BIB22","doi-asserted-by":"crossref","unstructured":"Lomashvili KA, Cobbs S, Hennigar RA, Hardcastle KI, O'Neill WC. Phosphate-induced vascular calcification: role of pyrophosphate and osteopontin. J Am Soc Nephrol2004; 15: 1392\u20131401","DOI":"10.1097\/01.ASN.0000128955.83129.9C"}],"container-title":["Nephrology Dialysis Transplantation"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/ndt\/article-pdf\/20\/7\/1370\/5395154\/gfh834.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,10,11]],"date-time":"2017-10-11T01:01:51Z","timestamp":1507683711000},"score":1,"resource":{"primary":{"URL":"http:\/\/academic.oup.com\/ndt\/article\/20\/7\/1370\/1912193\/125Dihydroxyvitamin-D3-but-not-cinacalcet-HCl"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,4,26]]},"references-count":22,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2005,4,26]]},"published-print":{"date-parts":[[2005,7,1]]}},"URL":"https:\/\/doi.org\/10.1093\/ndt\/gfh834","relation":{},"ISSN":["1460-2385","0931-0509"],"issn-type":[{"value":"1460-2385","type":"electronic"},{"value":"0931-0509","type":"print"}],"subject":[],"published-other":{"date-parts":[[2005,7]]},"published":{"date-parts":[[2005,4,26]]}}}