{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,24]],"date-time":"2026-01-24T20:08:56Z","timestamp":1769285336905,"version":"3.49.0"},"reference-count":41,"publisher":"Oxford University Press (OUP)","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2006,7,1]]},"DOI":"10.1093\/ndt\/gfl114","type":"journal-article","created":{"date-parts":[[2006,4,8]],"date-time":"2006-04-08T00:14:05Z","timestamp":1144455245000},"page":"1999-2004","source":"Crossref","is-referenced-by-count":93,"title":["Successful treatment of calciphylaxis with cinacalcet\u2014an alternative to parathyroidectomy?"],"prefix":"10.1093","volume":"21","author":[{"given":"Nestor","family":"Velasco","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark S.","family":"MacGregor","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew","family":"Innes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ian G.","family":"MacKay","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2006,4,7]]},"reference":[{"key":"key\n\t\t\t\t20171012172640_BIB1","doi-asserted-by":"crossref","unstructured":"Janigan DT, Hirsch DJ, Klassen GA, MacDonald AS. Calcified subcutaneous arterioles with infarcts of the subcutis and skin (\u2018calciphylaxis\u2019) in chronic renal failure. Am J Kidney Dis2000; 35: 588\u2013597","DOI":"10.1016\/S0272-6386(00)70003-5"},{"key":"key\n\t\t\t\t20171012172640_BIB2","doi-asserted-by":"crossref","unstructured":"Wilmer WA, Magro CM. Calciphylaxis: emerging concepts in prevention, diagnosis, and treatment. Sem Dial2002; 15: 172\u2013186","DOI":"10.1046\/j.1525-139X.2002.00052.x"},{"key":"key\n\t\t\t\t20171012172640_BIB3","doi-asserted-by":"crossref","unstructured":"Arch-Ferrer JE, Beenken SW, Rue LW, Bland KI, Diethelm AG. Therapy for calciphylaxis: an outcome analysis. Surgery2003; 134: 941\u2013944","DOI":"10.1016\/j.surg.2003.07.001"},{"key":"key\n\t\t\t\t20171012172640_BIB4","doi-asserted-by":"crossref","unstructured":"Oikawa S, Osajima A, Tamura M et al. Development of proximal calciphylaxis with penile involvement after parathyroidectomy in a patient on hemodialysis. Intern Med2004; 43: 63\u201368","DOI":"10.2169\/internalmedicine.43.63"},{"key":"key\n\t\t\t\t20171012172640_BIB5","doi-asserted-by":"crossref","unstructured":"Block GA, Martin KJ, de Francisco AL et al. Cinacalcet for secondary hyperparathyroidism in patients receiving hemodialysis. N Engl J Med2004; 350: 1516\u20131525","DOI":"10.1056\/NEJMoa031633"},{"key":"key\n\t\t\t\t20171012172640_BIB6","doi-asserted-by":"crossref","unstructured":"Lindberg JS, Culleton B, Wong G et al. Cinacalcet HCl, an oral calcimimetic agent for the treatment of secondary hyperparathyroidism in hemodialysis and peritoneal dialysis: a randomized, double-blind, multicenter study. J Am Soc Nephrol2005; 16: 800\u2013807","DOI":"10.1681\/ASN.2004060512"},{"key":"key\n\t\t\t\t20171012172640_BIB7","doi-asserted-by":"crossref","unstructured":"Selye H, Gabbiani G, Tuchweber B. Effect of parathyroidectomy and ferric dextrin upon calciphylactic sensitization by uremia. J Urol1963; 90: 120\u2013124","DOI":"10.1016\/S0022-5347(17)64373-8"},{"key":"key\n\t\t\t\t20171012172640_BIB8","doi-asserted-by":"crossref","unstructured":"Gipstein RM, Coburn JW, Adams DA et al. Calciphylaxis in man. A syndrome of tissue necrosis and vascular calcification in 11 patients with chronic renal failure. Arch Intern Med1976; 136: 1273\u20131280","DOI":"10.1001\/archinte.1976.03630110043012"},{"key":"key\n\t\t\t\t20171012172640_BIB9","doi-asserted-by":"crossref","unstructured":"Hafner J, Keusch G, Wahl C et al. Uremic small-artery disease with medial calcification and intimal hyperplasia (so-called calciphylaxis): a complication of chronic renal failure and benefit from parathyroidectomy. J Am Acad Dermatol1995; 33: 954\u2013962","DOI":"10.1016\/0190-9622(95)90286-4"},{"key":"key\n\t\t\t\t20171012172640_BIB10","doi-asserted-by":"crossref","unstructured":"Kang AS, McCarthy JT, Rowland C, Farley DR, van Heerden JA. Is calciphylaxis best treated surgically or medically? Surgery2000; 128: 967\u2013971","DOI":"10.1067\/msy.2000.110429"},{"key":"key\n\t\t\t\t20171012172640_BIB11","doi-asserted-by":"crossref","unstructured":"Mazhar AR, Johnson RJ, Gillen D et al. Risk factors and mortality associated with calciphylaxis in end-stage renal disease. Kidney Int200160: 324\u2013332","DOI":"10.1046\/j.1523-1755.2001.00803.x"},{"key":"key\n\t\t\t\t20171012172640_BIB12","doi-asserted-by":"crossref","unstructured":"Girotto JA, Harmon JW, Ratner LE, Nicol TL, Wong L, Chen H. Parathyroidectomy promotes wound healing and prolongs survival in patients with calciphylaxis from secondary hyperparathyroidism. Surgery2001; 130: 645\u2013650","DOI":"10.1067\/msy.2001.117101"},{"key":"key\n\t\t\t\t20171012172640_BIB13","doi-asserted-by":"crossref","unstructured":"Fine A, Zacharias J. Calciphylaxis is usually non-ulcerating: risk factors, outcome and therapy. Kidney Int2002; 61: 2210\u20132217","DOI":"10.1046\/j.1523-1755.2002.00375.x"},{"key":"key\n\t\t\t\t20171012172640_BIB14","doi-asserted-by":"crossref","unstructured":"Mirza I, Chaubay D, Gunderia H, Shih W, El-Fanel H. An unusual presentation of calciphylaxis due to primary hyperparathyroidism. Arch Pathol Lab Med2001; 125: 1351\u20131353","DOI":"10.5858\/2001-125-1351-AUPOCD"},{"key":"key\n\t\t\t\t20171012172640_BIB15","doi-asserted-by":"crossref","unstructured":"Wenzel-Seifert K, Harwig S, Keller F. Fulminant calcinosis in two patients after kidney transplantation. Am J Nephrol1991; 11: 497\u2013500","DOI":"10.1159\/000168367"},{"key":"key\n\t\t\t\t20171012172640_BIB16","doi-asserted-by":"crossref","unstructured":"Barbur MA, Kurjak M, Becker K. Systemische Kalziphylaxie bei chronischer Niereninsuffizienz: fulminanter Verlauf nach Nierentransplantation. Pathologe1997; 18: 453\u2013458","DOI":"10.1007\/s002920050241"},{"key":"key\n\t\t\t\t20171012172640_BIB17","doi-asserted-by":"crossref","unstructured":"Korkmaz C, Dundar E, Zubaroglu I. Calciphylaxis in a patient with rheumatoid arthritis without renal failure and hyperparathyroidism: the possible role of long-term steroid use and protein S deficiency. Clin Rheumatol2002; 21: 66\u201369","DOI":"10.1007\/s100670200016"},{"key":"key\n\t\t\t\t20171012172640_BIB18","doi-asserted-by":"crossref","unstructured":"Riegert-Johnson DL, Kaur JS, Pfeifer EA. Calciphylaxis associated with cholangiocarcinoma treated with low-molecular-weight heparin and vitamin K. Mayo Clin Proc2001; 76: 749\u2013752","DOI":"10.4065\/76.7.749"},{"key":"key\n\t\t\t\t20171012172640_BIB19","doi-asserted-by":"crossref","unstructured":"Goyal S, Huhn KM, Provost TT. Calciphylaxis in a patient without renal failure or elevated parathyroid hormone: possible aetiological role of chemotherapy. Br J Dermatol2000; 143: 1087\u20131090","DOI":"10.1046\/j.1365-2133.2000.03853.x"},{"key":"key\n\t\t\t\t20171012172640_BIB20","doi-asserted-by":"crossref","unstructured":"Giacobetti R, Feldman SA, Ivanovich P, Huang CM, Levin ML. Sudden fatal pulmonary calcification following renal transplantation. Nephron1977; 19: 295\u2013300","DOI":"10.1159\/000180903"},{"key":"key\n\t\t\t\t20171012172640_BIB21","doi-asserted-by":"crossref","unstructured":"Khafif RA, Delima C, Silverberg A, Frankel R, Groopman J. Acute hyperparathyroidism with systemic calcinosis. Report of a case. Arch Intern Med1989; 149: 681\u2013684","DOI":"10.1001\/archinte.1989.00390030133026"},{"key":"key\n\t\t\t\t20171012172640_BIB22","doi-asserted-by":"crossref","unstructured":"Llach F, Velasquez Forero F. Secondary hyperparathyroidism in chronic renal failure: pathogenic and clinical aspects. Am J Kidney Dis2001; 38 [Suppl 5]: S20\u2013S33","DOI":"10.1053\/ajkd.2001.28113"},{"key":"key\n\t\t\t\t20171012172640_BIB23","doi-asserted-by":"crossref","unstructured":"Block GA, Klassen PS, Lazarus JM, Ofsthun N, Lowrie EG, Chertow GM. Mineral metabolism, mortality, and morbidity in maintenance hemodialysis. J Am Soc Nephrol2004; 15: 2208\u20132218","DOI":"10.1097\/01.ASN.0000133041.27682.A2"},{"key":"key\n\t\t\t\t20171012172640_BIB24","doi-asserted-by":"crossref","unstructured":"Zacharias JM, Fontaine B, Fine A. Calcium use increases risk of calciphylaxis: a case-control study. Peritoneal Dial Int1999; 19: 248\u2013252","DOI":"10.1177\/089686089901900310"},{"key":"key\n\t\t\t\t20171012172640_BIB25","doi-asserted-by":"crossref","unstructured":"Coates T, Kirkland GS, Dymock RB et al. Cutaneous necrosis from calcific uremic arteriolopathy. Am J Kidney Dis1998; 32: 384\u2013391","DOI":"10.1053\/ajkd.1998.v32.pm9740153"},{"key":"key\n\t\t\t\t20171012172640_BIB26","doi-asserted-by":"crossref","unstructured":"Charytan C, Coburn JW, Chonchol M et al. Cinacalcet hydrochloride is an effective treatment for secondary hyperparathyroidism in patients with CKD not receiving dialysis. Am J Kidney Dis2005; 46: 58\u201367","DOI":"10.1053\/j.ajkd.2005.04.013"},{"key":"key\n\t\t\t\t20171012172640_BIB27","doi-asserted-by":"crossref","unstructured":"Kruse AE, Eisenberger U, Frey FJ, Mohaupt MG. The calcimimetic cinacalcet normalizes serum calcium in renal transplant patients with persistent hyperparathyroidism. Nephrol Dial Transplant2005; 20: 1311\u20131314","DOI":"10.1093\/ndt\/gfh924"},{"key":"key\n\t\t\t\t20171012172640_BIB28","doi-asserted-by":"crossref","unstructured":"Serra AL, Schwarz AA, Wick FH, Marti HP, Wuthrich RP. Successful treatment of hypercalcemia with cinacalcet in renal transplant recipients with persistent hyperparathyroidism. Nephrol Dial Transplant2005; 20: 1315\u20131319","DOI":"10.1093\/ndt\/gfh925"},{"key":"key\n\t\t\t\t20171012172640_BIB29","doi-asserted-by":"crossref","unstructured":"Goldsmith DJ. Calcifying panniculitis or \u2018simple\u2019 inflammation? Biopsy is better than a bone scan. Nephrol Dial Transplant1997; 12: 2463\u20132464","DOI":"10.1093\/ndt\/12.11.2463"},{"key":"key\n\t\t\t\t20171012172640_BIB30","doi-asserted-by":"crossref","unstructured":"Cicone JS, Petronis JB, Embert CD, Spector DA. Successful treatment of calciphylaxis with intravenous sodium thiosulfate. Am J Kidney Dis2004; 43: 1104\u20131108","DOI":"10.1053\/j.ajkd.2004.03.018"},{"key":"key\n\t\t\t\t20171012172640_BIB31","doi-asserted-by":"crossref","unstructured":"Lien YH, Silva AL, Whittman D. Effects of cinacalcet on bone mineral density in patients with secondary hyperparathyroidism. Nephrol Dial Transplant2005;20: 1232\u20131237","DOI":"10.1093\/ndt\/gfh829"},{"key":"key\n\t\t\t\t20171012172640_BIB32","doi-asserted-by":"crossref","unstructured":"Cunningham J, Danese M, Olson K, Klassen P, Chertow GM. Effects of the calcimimetic cinacalcet HCl on cardiovascular disease, fracture, and health-related quality of life in secondary hyperparathyroidism. Kidney Int2005; 68: 1793\u20131800","DOI":"10.1111\/j.1523-1755.2005.00596.x"},{"key":"key\n\t\t\t\t20171012172640_BIB33","doi-asserted-by":"crossref","unstructured":"National Kidney Foundation. K\/DOQI clinical practice guidelines for bone metabolism and disease in chronic kidney disease. Am J Kidney Dis2003; 42 [Suppl 3]: S1\u2013S201","DOI":"10.1016\/S0272-6386(03)00905-3"},{"key":"key\n\t\t\t\t20171012172640_BIB34","doi-asserted-by":"crossref","unstructured":"Vassa N, Twardowski ZJ, Campbell J. Hyperbaric oxygen therapy in calciphylaxis-induced skin necrosis in a peritoneal dialysis patient. Am J Kidney Dis1994; 23: 878\u2013881","DOI":"10.1016\/S0272-6386(12)80145-4"},{"key":"key\n\t\t\t\t20171012172640_BIB35","doi-asserted-by":"crossref","unstructured":"Dean SM, Werman H. Calciphylaxis: a favorable outcome with hyperbaric oxygen. Vascular Med1998; 3: 115\u2013120","DOI":"10.1177\/1358836X9800300205"},{"key":"key\n\t\t\t\t20171012172640_BIB36","doi-asserted-by":"crossref","unstructured":"Podymow T, Wherrett C, Burns KD. Hyperbaric oxygen in the treatment of calciphylaxis: a case series. Nephrol Dial Transplant2001; 16: 2176\u20132180","DOI":"10.1093\/ndt\/16.11.2176"},{"key":"key\n\t\t\t\t20171012172640_BIB37","doi-asserted-by":"crossref","unstructured":"Dwyer KM, Francis DM, Hill PA, Murphy BF. Calcific uraemic arteriolopathy: local treatment and hyperbaric oxygen therapy. Nephrol Dial Transplant2002; 17: 1148\u20131149","DOI":"10.1093\/ndt\/17.6.1148"},{"key":"key\n\t\t\t\t20171012172640_BIB38","unstructured":"Basile C, Montanaro A, Masi M, Pati G, De Maio P, Gismondi A. Hyperbaric oxygen therapy for calcific uremic arteriolopathy: a case series. J Nephrol2002; 15: 676\u2013680"},{"key":"key\n\t\t\t\t20171012172640_BIB39","doi-asserted-by":"crossref","unstructured":"Guerra G, Shah RC, Ross EA. Rapid resolution of calciphylaxis with intravenous sodium thiosulfate and continuous venovenous haemofiltration using low calcium replacement fluid: case report. Nephrol Dial Transplant2005; 20: 1260\u20131262","DOI":"10.1093\/ndt\/gfh825"},{"key":"key\n\t\t\t\t20171012172640_BIB40","doi-asserted-by":"crossref","unstructured":"Monney P, Nguyen QV, Perroud H, Descombes E. Rapid improvement of calciphylaxis after intravenous pamidronate therapy in a patient with chronic renal failure. Nephrol Dial Transplant2004; 19: 2130\u20132132","DOI":"10.1093\/ndt\/gfh305"},{"key":"key\n\t\t\t\t20171012172640_BIB41","doi-asserted-by":"crossref","unstructured":"Foley RN, Li S, Liu J, Gilbertson DT, Chen SC, Collins AJ. The fall and rise of parathyroidectomy in U.S. hemodialysis patients, 1992 to 2002. J Am Soc Nephrol2005; 16: 210\u2013218","DOI":"10.1681\/ASN.2004020138"}],"container-title":["Nephrology Dialysis Transplantation"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/ndt\/article-pdf\/21\/7\/1999\/5157059\/gfl114.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,25]],"date-time":"2021-07-25T13:01:27Z","timestamp":1627218087000},"score":1,"resource":{"primary":{"URL":"http:\/\/academic.oup.com\/ndt\/article\/21\/7\/1999\/1821919\/Successful-treatment-of-calciphylaxis-with"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,4,7]]},"references-count":41,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2006,4,7]]},"published-print":{"date-parts":[[2006,7,1]]}},"URL":"https:\/\/doi.org\/10.1093\/ndt\/gfl114","relation":{},"ISSN":["1460-2385","0931-0509"],"issn-type":[{"value":"1460-2385","type":"electronic"},{"value":"0931-0509","type":"print"}],"subject":[],"published-other":{"date-parts":[[2006,7]]},"published":{"date-parts":[[2006,4,7]]}}}