{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T11:26:28Z","timestamp":1774351588536,"version":"3.50.1"},"reference-count":55,"publisher":"Oxford University Press (OUP)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nephrology Dialysis Transplantation"],"published-print":{"date-parts":[[2011,1,1]]},"DOI":"10.1093\/ndt\/gfq384","type":"journal-article","created":{"date-parts":[[2010,7,9]],"date-time":"2010-07-09T00:30:51Z","timestamp":1278635451000},"page":"92-100","source":"Crossref","is-referenced-by-count":59,"title":["Inhibition of mTOR with sirolimus does not attenuate progression of liver and kidney disease in PCK rats"],"prefix":"10.1093","volume":"26","author":[{"given":"C.","family":"Renken","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.-C.","family":"Fischer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Kundt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N.","family":"Gretz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Haffner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2010,7,7]]},"reference":[{"issue":"3","key":"1_22278447","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1007\/BF03256455","volume":"10","author":"Bergmann","year":"2006","ISSN":"https:\/\/id.crossref.org\/issn\/1177-1062","issn-type":"print"},{"issue":"2","key":"2_5927891","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1002\/(SICI)1096-8628(19980305)76:2<137::AID-AJMG6>3.0.CO;2-Q","volume":"76","author":"Zerres","year":"1998","journal-title":"American journal of medical genetics","ISSN":"https:\/\/id.crossref.org\/issn\/0148-7299","issn-type":"print"},{"key":"3_32375239","doi-asserted-by":"publisher","first-page":"321","DOI":"10.1146\/annurev.med.60.101707.125712","volume":"60","author":"Harris","year":"2009","journal-title":"Annual review of medicine","ISSN":"https:\/\/id.crossref.org\/issn\/0066-4219","issn-type":"print"},{"issue":"2","key":"4_33383882","doi-asserted-by":"publisher","first-page":"100","DOI":"10.1007\/s00247-008-1064-x","volume":"39","author":"Turkbey","year":"2009","journal-title":"Pediatric radiology","ISSN":"https:\/\/id.crossref.org\/issn\/0301-0449","issn-type":"print"},{"issue":"5","key":"6_15849574","first-page":"1101","volume":"56","author":"Guay-Woodford","year":"1995","journal-title":"American journal of human genetics","ISSN":"https:\/\/id.crossref.org\/issn\/0002-9297","issn-type":"print"},{"issue":"5","key":"7_17003867","doi-asserted-by":"publisher","first-page":"1305","DOI":"10.1086\/340448","volume":"70","author":"Onuchic","year":"2002","journal-title":"American journal of human genetics","ISSN":"https:\/\/id.crossref.org\/issn\/0002-9297","issn-type":"print"},{"issue":"3","key":"8_16981352","doi-asserted-by":"publisher","first-page":"259","DOI":"10.1038\/ng833","volume":"30","author":"Ward","year":"2002","journal-title":"Nature genetics","ISSN":"https:\/\/id.crossref.org\/issn\/1061-4036","issn-type":"print"},{"issue":"18","key":"9_21967141","doi-asserted-by":"publisher","first-page":"2189","DOI":"10.1093\/bioinformatics\/btl123","volume":"22","year":"2006","journal-title":"Bioinformatics","ISSN":"https:\/\/id.crossref.org\/issn\/1367-4803","issn-type":"print"},{"issue":"45","key":"10_22571686","doi-asserted-by":"publisher","first-page":"34357","DOI":"10.1074\/jbc.M606740200","volume":"281","year":"2006","journal-title":"Journal of Biological Chemistry","ISSN":"https:\/\/id.crossref.org\/issn\/0021-9258","issn-type":"print"},{"issue":"8","key":"11_28486666","doi-asserted-by":"publisher","first-page":"942","DOI":"10.1093\/hmg\/ddm039","volume":"16","author":"Kaimori","year":"2007","journal-title":"Human Molecular Genetics","ISSN":"https:\/\/id.crossref.org\/issn\/0964-6906","issn-type":"print"},{"issue":"3","key":"12_17027390","doi-asserted-by":"publisher","first-page":"309","DOI":"10.1097\/00041552-200205000-00007","volume":"11","author":"Harris","year":"2002","journal-title":"Current opinion in nephrology and hypertension","ISSN":"https:\/\/id.crossref.org\/issn\/1062-4821","issn-type":"print"},{"issue":"3","key":"13_30354378","doi-asserted-by":"publisher","first-page":"455","DOI":"10.1681\/ASN.2007070770","volume":"19","year":"2008","journal-title":"Journal of the American Society of Nephrology","ISSN":"https:\/\/id.crossref.org\/issn\/1046-6673","issn-type":"print"},{"issue":"46","key":"14_31880212","doi-asserted-by":"publisher","first-page":"31559","DOI":"10.1074\/jbc.M805452200","volume":"283","year":"2008","journal-title":"Journal of Biological Chemistry","ISSN":"https:\/\/id.crossref.org\/issn\/0021-9258","issn-type":"print"},{"issue":"8","key":"15_23583964","doi-asserted-by":"publisher","first-page":"3241","DOI":"10.1128\/MCB.00072-07","volume":"27","year":"2007","journal-title":"Molecular and Cellular Biology","ISSN":"https:\/\/id.crossref.org\/issn\/0270-7306","issn-type":"print"},{"issue":"22","key":"16_22645116","doi-asserted-by":"publisher","first-page":"3280","DOI":"10.1093\/hmg\/ddl404","volume":"15","year":"2006","journal-title":"Human Molecular Genetics","ISSN":"https:\/\/id.crossref.org\/issn\/0964-6906","issn-type":"print"},{"issue":"12","key":"17_21238181","doi-asserted-by":"crossref","first-page":"928","DOI":"10.1038\/nrg1727","volume":"6","author":"Hildebrandt","year":"2005","journal-title":"Nature reviews. Genetics","ISSN":"https:\/\/id.crossref.org\/issn\/1471-0056","issn-type":"print"},{"key":"18_31221271","doi-asserted-by":"crossref","first-page":"4451","DOI":"10.2741\/3016","volume":"13","author":"Kolb","year":"2008","journal-title":"Frontiers in bioscience : a journal and virtual library","ISSN":"https:\/\/id.crossref.org\/issn\/1093-9946","issn-type":"print"},{"issue":"3","key":"19_34310061","doi-asserted-by":"publisher","first-page":"p39","DOI":"10.1159\/000178978","volume":"111","author":"Veland","year":"2009","journal-title":"Nephron. Clinical practice [electronic resource]","ISSN":"https:\/\/id.crossref.org\/issn\/1660-2129","issn-type":"print"},{"issue":"14","key":"20_21838571","doi-asserted-by":"publisher","first-page":"5466","DOI":"10.1073\/pnas.0509694103","volume":"103","year":"2006","journal-title":"PNAS","ISSN":"https:\/\/id.crossref.org\/issn\/0027-8424","issn-type":"print"},{"issue":"3","key":"21_21064661","doi-asserted-by":"publisher","first-page":"598","DOI":"10.1093\/ndt\/gfi181","volume":"21","year":"2006","journal-title":"Nephrology Dialysis Transplantation","ISSN":"https:\/\/id.crossref.org\/issn\/0931-0509","issn-type":"print"},{"issue":"3","key":"22_30282670","doi-asserted-by":"publisher","first-page":"631","DOI":"10.1681\/ASN.2007050626","volume":"19","year":"2008","journal-title":"Journal of the American Society of Nephrology","ISSN":"https:\/\/id.crossref.org\/issn\/1046-6673","issn-type":"print"},{"issue":"4","key":"23_29072984","doi-asserted-by":"publisher","first-page":"357","DOI":"10.1111\/j.1440-1797.2007.00811.x","volume":"12","author":"Wahl","year":"2007","journal-title":"Nephrology (Carlton, Vic.)","ISSN":"https:\/\/id.crossref.org\/issn\/1320-5358","issn-type":"print"},{"issue":"7","key":"24_22126320","doi-asserted-by":"publisher","first-page":"1752","DOI":"10.1093\/ndt\/gfl246","volume":"21","year":"2006","journal-title":"Nephrology Dialysis Transplantation","ISSN":"https:\/\/id.crossref.org\/issn\/0931-0509","issn-type":"print"},{"key":"25_29452174","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1186\/1471-2369-8-13","volume":"8","author":"Serra","year":"2007","journal-title":"BMC nephrology [electronic resource]","ISSN":"https:\/\/id.crossref.org\/issn\/1471-2369","issn-type":"print"},{"issue":"11","key":"26_35051259","doi-asserted-by":"publisher","first-page":"3334","DOI":"10.1093\/ndt\/gfp280","volume":"24","year":"2009","journal-title":"Nephrology Dialysis Transplantation","ISSN":"https:\/\/id.crossref.org\/issn\/0931-0509","issn-type":"print"},{"issue":"6","key":"27_33709836","doi-asserted-by":"publisher","first-page":"1819","DOI":"10.1093\/ndt\/gfn744","volume":"24","year":"2009","journal-title":"Nephrology Dialysis Transplantation","ISSN":"https:\/\/id.crossref.org\/issn\/0931-0509","issn-type":"print"},{"issue":"1","key":"28_10307614","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1538\/expanim.49.51","volume":"49","author":"Katsuyama","year":"2000","journal-title":"Experimental animals \/ Japanese Association for Laboratory Animal Science","ISSN":"https:\/\/id.crossref.org\/issn\/1341-1357","issn-type":"print"},{"key":"29_33014354","first-page":"1303","volume":"125","year":"2003","ISSN":"https:\/\/id.crossref.org\/issn\/1528-0012","issn-type":"print"},{"issue":"5","key":"30_18491845","doi-asserted-by":"crossref","first-page":"1719","DOI":"10.1016\/S0002-9440(10)63427-X","volume":"165","author":"Masyuk","year":"2004","journal-title":"American Journal Of Pathology","ISSN":"https:\/\/id.crossref.org\/issn\/0002-9440","issn-type":"print"},{"issue":"9","key":"31_22537013","doi-asserted-by":"publisher","first-page":"940","DOI":"10.1038\/labinvest.3700448","volume":"86","author":"Muff","year":"2006","journal-title":"Laboratory investigation; a journal of technical methods and pathology","ISSN":"https:\/\/id.crossref.org\/issn\/0023-6837","issn-type":"print"},{"issue":"1","key":"32_11009691","doi-asserted-by":"publisher","first-page":"126","DOI":"10.1046\/j.1523-1755.2001.00473.x","volume":"59","author":"Lager","year":"2001","journal-title":"Kidney international","ISSN":"https:\/\/id.crossref.org\/issn\/0085-2538","issn-type":"print"},{"issue":"3","key":"33_18881881","doi-asserted-by":"publisher","first-page":"551","DOI":"10.1007\/s00441-005-1108-6","volume":"320","author":"Borges","year":"2005","journal-title":"Cell and tissue research","ISSN":"https:\/\/id.crossref.org\/issn\/0302-766X","issn-type":"print"},{"issue":"7","key":"34_30740153","doi-asserted-by":"publisher","first-page":"1331","DOI":"10.1681\/ASN.2007060665","volume":"19","year":"2008","journal-title":"Journal of the American Society of Nephrology","ISSN":"https:\/\/id.crossref.org\/issn\/1046-6673","issn-type":"print"},{"issue":"3","key":"35_30283213","doi-asserted-by":"publisher","first-page":"269","DOI":"10.1038\/sj.ki.5002629","volume":"73","author":"Nagao","year":"2008","journal-title":"Kidney international","ISSN":"https:\/\/id.crossref.org\/issn\/0085-2538","issn-type":"print"},{"issue":"14","key":"36_21833982","doi-asserted-by":"publisher","first-page":"5247","DOI":"10.1073\/pnas.0601352103","volume":"103","year":"2006","journal-title":"PNAS","ISSN":"https:\/\/id.crossref.org\/issn\/0027-8424","issn-type":"print"},{"issue":"48","key":"37_22815945","doi-asserted-by":"publisher","first-page":"6373","DOI":"10.1038\/sj.onc.1209889","volume":"25","author":"Reiling","year":"2006","journal-title":"Oncogene","ISSN":"https:\/\/id.crossref.org\/issn\/0950-9232","issn-type":"print"},{"issue":"16","key":"38_18293218","doi-asserted-by":"publisher","first-page":"1926","DOI":"10.1101\/gad.1212704","volume":"18","author":"Hay","year":"2004","journal-title":"Genes &amp; Development","ISSN":"https:\/\/id.crossref.org\/issn\/0890-9369","issn-type":"print"},{"key":"39_30100568","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1146\/annurev.pharmtox.47.120505.105359","volume":"47","year":"2007","journal-title":"Annual review of pharmacology and toxicology","ISSN":"https:\/\/id.crossref.org\/issn\/1545-4304","issn-type":"print"},{"key":"40_22614356","doi-asserted-by":"publisher","first-page":"362","DOI":"10.1152\/physiol.00024.2006","volume":"21","author":"Wang","year":"2006","journal-title":"Physiology","ISSN":"https:\/\/id.crossref.org\/issn\/1548-9213","issn-type":"print"},{"issue":"3","key":"41_21611757","doi-asserted-by":"publisher","first-page":"471","DOI":"10.1016\/j.cell.2006.01.016","volume":"124","author":"Wullschleger","year":"2006","journal-title":"Cell","ISSN":"https:\/\/id.crossref.org\/issn\/0092-8674","issn-type":"print"},{"issue":"8","key":"42_34422525","doi-asserted-by":"publisher","first-page":"2349","DOI":"10.1093\/ndt\/gfp129","volume":"24","year":"2009","journal-title":"Nephrology Dialysis Transplantation","ISSN":"https:\/\/id.crossref.org\/issn\/0931-0509","issn-type":"print"},{"issue":"10","key":"43_11373664","doi-asserted-by":"publisher","first-page":"2120","DOI":"10.1023\/A:1011942310737","volume":"46","author":"Deters","year":"2001","journal-title":"Digestive diseases and sciences","ISSN":"https:\/\/id.crossref.org\/issn\/0163-2116","issn-type":"print"},{"issue":"4","key":"44_29426656","doi-asserted-by":"publisher","first-page":"381","DOI":"10.1038\/sj.clpt.6100317","volume":"82","author":"Hartford","year":"2007","journal-title":"Clinical pharmacology and therapeutics","ISSN":"https:\/\/id.crossref.org\/issn\/0009-9236","issn-type":"print"},{"issue":"48","key":"45_22815943","doi-asserted-by":"publisher","first-page":"6347","DOI":"10.1038\/sj.onc.1209885","volume":"25","author":"Corradetti","year":"2006","journal-title":"Oncogene","ISSN":"https:\/\/id.crossref.org\/issn\/0950-9232","issn-type":"print"},{"issue":"2","key":"46_27970455","doi-asserted-by":"publisher","first-page":"217","DOI":"10.1042\/BJ20070024","volume":"403","author":"Proud","year":"2007","journal-title":"The Biochemical journal","ISSN":"https:\/\/id.crossref.org\/issn\/0264-6021","issn-type":"print"},{"issue":"7","key":"47_34245630","doi-asserted-by":"crossref","first-page":"1026","DOI":"10.4161\/cc.8.7.8044","volume":"8","author":"Foster","year":"2009","journal-title":"Cell cycle (Georgetown, Tex.)","ISSN":"https:\/\/id.crossref.org\/issn\/1538-4101","issn-type":"print"},{"issue":"16","key":"48_19553515","doi-asserted-by":"publisher","first-page":"13907","DOI":"10.1074\/jbc.M110782200","volume":"277","year":"2002","journal-title":"Journal of Biological Chemistry","ISSN":"https:\/\/id.crossref.org\/issn\/0021-9258","issn-type":"print"},{"issue":"4","key":"49_33956048","doi-asserted-by":"crossref","first-page":"567","DOI":"10.4161\/cc.8.4.7659","volume":"8","author":"Choo","year":"2009","journal-title":"Cell cycle (Georgetown, Tex.)","ISSN":"https:\/\/id.crossref.org\/issn\/1538-4101","issn-type":"print"},{"issue":"9","key":"50_33561772","doi-asserted-by":"publisher","first-page":"1187","DOI":"10.1038\/onc.2008.490","volume":"28","author":"Chaturvedi","year":"2009","journal-title":"Oncogene","ISSN":"https:\/\/id.crossref.org\/issn\/0950-9232","issn-type":"print"},{"issue":"12","key":"51_35893684","doi-asserted-by":"publisher","first-page":"620","DOI":"10.1016\/j.tibs.2009.09.004","volume":"34","author":"Cybulski","year":"2009","journal-title":"Trends in biochemical sciences","ISSN":"https:\/\/id.crossref.org\/issn\/0167-7640","issn-type":"print"},{"issue":"5712","key":"52_18688422","doi-asserted-by":"publisher","first-page":"1098","DOI":"10.1126\/science.1106148","volume":"307","author":"Sarbassov","year":"2005","journal-title":"Science","ISSN":"https:\/\/id.crossref.org\/issn\/0036-8075","issn-type":"print"},{"issue":"8","key":"53_22827043","doi-asserted-by":"publisher","first-page":"955","DOI":"10.1038\/sj.bjc.6603353","volume":"95","author":"Kurmasheva","year":"2006","journal-title":"British Journal of Cancer","ISSN":"https:\/\/id.crossref.org\/issn\/1532-1827","issn-type":"print"},{"key":"54_36044759","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1097\/01.tp.0000225772.22757.5e","volume":"82","year":"2006","ISSN":"https:\/\/id.crossref.org\/issn\/1534-6080","issn-type":"print"},{"issue":"12","key":"55_35882745","doi-asserted-by":"publisher","first-page":"2493","DOI":"10.1681\/ASN.2008111186","volume":"20","year":"2009","journal-title":"Journal of the American Society of Nephrology","ISSN":"https:\/\/id.crossref.org\/issn\/1046-6673","issn-type":"print"},{"issue":"5","key":"56_18481269","doi-asserted-by":"publisher","first-page":"1766","DOI":"10.1111\/j.1523-1755.2004.00952.x","volume":"66","author":"Torres","year":"2004","journal-title":"Kidney international","ISSN":"https:\/\/id.crossref.org\/issn\/0085-2538","issn-type":"print"}],"container-title":["Nephrology Dialysis Transplantation"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/ndt\/article-pdf\/26\/1\/92\/5195382\/gfq384.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,10,31]],"date-time":"2021-10-31T03:45:06Z","timestamp":1635651906000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ndt\/article-lookup\/doi\/10.1093\/ndt\/gfq384"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,7,7]]},"references-count":55,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2010,12,21]]},"published-print":{"date-parts":[[2011,1,1]]}},"URL":"https:\/\/doi.org\/10.1093\/ndt\/gfq384","relation":{},"ISSN":["0931-0509","1460-2385"],"issn-type":[{"value":"0931-0509","type":"print"},{"value":"1460-2385","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,7,7]]}}}