{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T15:38:15Z","timestamp":1762875495948},"reference-count":34,"publisher":"Oxford University Press (OUP)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2013,6]]},"DOI":"10.1093\/ndt\/gfs517","type":"journal-article","created":{"date-parts":[[2012,12,11]],"date-time":"2012-12-11T01:35:24Z","timestamp":1355189724000},"page":"1407-1417","source":"Crossref","is-referenced-by-count":22,"title":["Intrauterine growth restriction leads to a dysregulation of Wilms\u2019 tumour supressor gene 1 (WT1) and to early podocyte alterations"],"prefix":"10.1093","volume":"28","author":[{"given":"Carlos","family":"Menendez-Castro","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karl F.","family":"Hilgers","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kerstin","family":"Amann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christoph","family":"Daniel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nada","family":"Cordasic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rainer","family":"Wachtveitl","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fabian","family":"Fahlbusch","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian","family":"Plank","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J\u00f6rg","family":"D\u00f6tsch","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wolfgang","family":"Rascher","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Hartner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2012,12,9]]},"reference":[{"key":"key\n\t\t\t\t20170518090812_GFS517C1","doi-asserted-by":"crossref","first-page":"1472","DOI":"10.1001\/archinte.160.10.1472","article-title":"Low birth weights contribute to high rates of early-onset chronic renal failure in the Southeastern United States","volume":"160","author":"Lackland","year":"2000","journal-title":"Arch Intern Med"},{"key":"key\n\t\t\t\t20170518090812_GFS517C2","doi-asserted-by":"crossref","first-page":"S31","DOI":"10.1046\/j.1523-1755.63.s83.8.x","article-title":"A stereological study of glomerular number and volume: preliminary findings in a multiracial study of kidneys at autopsy","author":"Hoy","year":"2003","journal-title":"Kidney Int Suppl"},{"key":"key\n\t\t\t\t20170518090812_GFS517C3","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1093\/ajh\/1.4.335","article-title":"Glomeruli and blood pressure. Less of one, more the other?","volume":"1","author":"Brenner","year":"1988","journal-title":"Am J Hypertens"},{"key":"key\n\t\t\t\t20170518090812_GFS517C4","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1042\/cs0950115","article-title":"In utero programming of chronic disease","volume":"95","author":"Barker","year":"1998","journal-title":"Clin Sci (Lond)"},{"key":"key\n\t\t\t\t20170518090812_GFS517C5","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1046\/j.1523-1755.2001.00484.x","article-title":"Prenatal programming of adult hypertension in the rat","volume":"59","author":"Vehaskari","year":"2001","journal-title":"Kidney Int"},{"key":"key\n\t\t\t\t20170518090812_GFS517C6","doi-asserted-by":"crossref","first-page":"S56","DOI":"10.1016\/j.placenta.2006.01.014","article-title":"Fetal programming: causes and consequences as revealed by studies of dietary manipulation in rats\u2014a review","volume":"27","author":"McArdle","year":"2006","journal-title":"Placenta"},{"key":"key\n\t\t\t\t20170518090812_GFS517C7","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1203\/00006450-200104000-00005","article-title":"Maternal protein restriction suppresses the newborn renin-angiotensin system and programs adult hypertension in rats","volume":"49","author":"Woods","year":"2001","journal-title":"Pediatr Res"},{"key":"key\n\t\t\t\t20170518090812_GFS517C8","doi-asserted-by":"crossref","first-page":"1974","DOI":"10.1038\/sj.ki.5001966","article-title":"Intrauterine growth retardation aggravates the course of acute mesangioproliferative glomerulonephritis in the rat","volume":"70","author":"Plank","year":"2006","journal-title":"Kidney Int"},{"key":"key\n\t\t\t\t20170518090812_GFS517C9","doi-asserted-by":"crossref","first-page":"e20369","DOI":"10.1371\/journal.pone.0020369","article-title":"Early and late postnatal myocardial and vascular changes in a protein restriction rat model of intrauterine growth restriction","volume":"6","author":"Menendez-Castro","year":"2011","journal-title":"PLoS One"},{"key":"key\n\t\t\t\t20170518090812_GFS517C10","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1111\/j.1523-1755.2004.00406.x","article-title":"Is there an association between level of adult blood pressure and nephron number or renal filtration surface area?","volume":"65","author":"Black","year":"2004","journal-title":"Kidney Int"},{"key":"key\n\t\t\t\t20170518090812_GFS517C11","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1053\/snep.2003.50015","article-title":"Animal models of FSGS: lessons for pathogenesis and treatment","volume":"23","author":"Fogo","year":"2003","journal-title":"Semin Nephrol"},{"key":"key\n\t\t\t\t20170518090812_GFS517C12","doi-asserted-by":"crossref","first-page":"1292","DOI":"10.1038\/ki.2011.278","article-title":"Induction of progressive glomerulonephritis by podocyte-specific overexpression of platelet-derived growth factor-D","volume":"80","author":"van Roeyen","year":"2011","journal-title":"Kidney Int"},{"key":"key\n\t\t\t\t20170518090812_GFS517C13","doi-asserted-by":"crossref","first-page":"2131","DOI":"10.1038\/sj.ki.5000410","article-title":"The podocyte's response to injury: role in proteinuria and glomerulosclerosis","volume":"69","author":"Shankland","year":"2006","journal-title":"Kidney Int"},{"key":"key\n\t\t\t\t20170518090812_GFS517C14","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/S1084-9521(03)00026-0","article-title":"WT1 and glomerular function","volume":"14","author":"Menke","year":"2003","journal-title":"Semin Cell Dev Biol"},{"key":"key\n\t\t\t\t20170518090812_GFS517C15","doi-asserted-by":"crossref","first-page":"61","DOI":"10.4161\/org.6.2.11928","article-title":"WT1 and kidney progenitor cells","volume":"6","author":"Kreidberg","year":"2010","journal-title":"Organogenesis"},{"key":"key\n\t\t\t\t20170518090812_GFS517C16","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1093\/hmg\/11.6.651","article-title":"WT1 is a key regulator of podocyte function: reduced expression levels cause crescentic glomerulonephritis and mesangial sclerosis","volume":"11","author":"Guo","year":"2002","journal-title":"Hum Mol Genet"},{"key":"key\n\t\t\t\t20170518090812_GFS517C17","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/S0092-8674(01)00453-6","article-title":"Two splice variants of the Wilms\u2019 tumor 1 gene have distinct functions during sex determination and nephron formation","volume":"106","author":"Hammes","year":"2001","journal-title":"Cell"},{"key":"key\n\t\t\t\t20170518090812_GFS517C18","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1093\/hmg\/7.4.709","article-title":"Frasier syndrome is caused by defective alternative splicing of WT1 leading to an altered ratio of WT1 +\/\u2212KTS splice isoforms","volume":"7","author":"Klamt","year":"1998","journal-title":"Hum Mol Genet"},{"key":"key\n\t\t\t\t20170518090812_GFS517C19","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1097\/HJH.0b013e32831997d6","article-title":"Statin treatment reduces glomerular inflammation and podocyte damage in rat deoxycorticosterone-acetate-salt hypertension","volume":"27","author":"Hartner","year":"2009","journal-title":"J Hypertens"},{"key":"key\n\t\t\t\t20170518090812_GFS517C20","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1038\/labinvest.3700052","article-title":"Comparison of renal morphology in the Streptozotocin and the SHR\/N-cp models of diabetes","volume":"84","author":"Gross","year":"2004","journal-title":"Lab Invest"},{"key":"key\n\t\t\t\t20170518090812_GFS517C21","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1053\/ajkd.2001.25209","article-title":"Glomerular osteopontin expression and macrophage infiltration in glomerulosclerosis of DOCA-salt rats","volume":"38","author":"Hartner","year":"2001","journal-title":"Am J Kidney Dis"},{"key":"key\n\t\t\t\t20170518090812_GFS517C22","doi-asserted-by":"crossref","first-page":"F1329","DOI":"10.1152\/ajprenal.00284.2005","article-title":"Role of fibrillin-1 in hypertensive and diabetic glomerular disease","volume":"290","author":"Hartner","year":"2006","journal-title":"Am J Physiol Renal Physiol"},{"key":"key\n\t\t\t\t20170518090812_GFS517C23","doi-asserted-by":"crossref","first-page":"S47","DOI":"10.1097\/01.hjh.0000358838.71675.5e","article-title":"Hypertension and kidney alterations in rat offspring from low protein pregnancies","volume":"27","author":"Villar-Martini","year":"2009","journal-title":"J Hypertens Suppl"},{"key":"key\n\t\t\t\t20170518090812_GFS517C24","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1007\/s00428-005-0134-9","article-title":"Upregulation of nestin, vimentin and desmin in rat podocytes in response to injury","volume":"448","author":"Zou","year":"2006","journal-title":"Virchows Arch"},{"key":"key\n\t\t\t\t20170518090812_GFS517C25","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1146\/annurev-physiol-020911-153238","article-title":"Cell biology and pathology of podocytes","volume":"74","author":"Greka","year":"2012","journal-title":"Annu Rev Physiol"},{"key":"key\n\t\t\t\t20170518090812_GFS517C26","doi-asserted-by":"crossref","first-page":"F1151","DOI":"10.1152\/ajprenal.00058.2010","article-title":"Lack of {alpha}8-integrin aggravates podocyte injury in experimental diabetic nephropathy","volume":"299","author":"Hartner","year":"2010","journal-title":"Am J Physiol Ren Physiol"},{"key":"key\n\t\t\t\t20170518090812_GFS517C27","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1002\/path.1390","article-title":"The wt1-heterozygous mouse; a model to study the development of glomerular sclerosis","volume":"200","author":"Menke","year":"2003","journal-title":"J Pathol"},{"key":"key\n\t\t\t\t20170518090812_GFS517C28","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1681\/ASN.2007040471","article-title":"How do mesangial and endothelial cells form the glomerular tuft?","volume":"19","author":"Vaughan","year":"2008","journal-title":"J Am Soc Nephrol"},{"key":"key\n\t\t\t\t20170518090812_GFS517C29","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1016\/0092-8674(93)90515-R","article-title":"WT-1 is required for early kidney development","volume":"74","author":"Kreidberg","year":"1993","journal-title":"Cell"},{"key":"key\n\t\t\t\t20170518090812_GFS517C30","doi-asserted-by":"crossref","first-page":"1653","DOI":"10.1242\/jcs.00405","article-title":"The complex life of WT1","volume":"116","author":"Wagner","year":"2003","journal-title":"J Cell Sci"},{"key":"key\n\t\t\t\t20170518090812_GFS517C31","doi-asserted-by":"crossref","first-page":"F12","DOI":"10.1152\/ajprenal.00597.2007","article-title":"New insights into the function of the Wilms tumor suppressor gene WT1 in podocytes","volume":"295","author":"Morrison","year":"2008","journal-title":"Am J Physiol Ren Physiol"},{"key":"key\n\t\t\t\t20170518090812_GFS517C32","doi-asserted-by":"crossref","first-page":"975","DOI":"10.1158\/1541-7786.MCR-10-0033","article-title":"The predominant WT1 isoform (+KTS) encodes a DNA-binding protein targeting the planar cell polarity gene Scribble in renal podocytes","volume":"8","author":"Wells","year":"2010","journal-title":"Mol Cancer Res"},{"key":"key\n\t\t\t\t20170518090812_GFS517C33","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1007\/BF00230355","article-title":"Podocyte damage is a critical step in the development of glomerulosclerosis in the uninephrectomised-desoxycorticosterone hypertensive rat","volume":"425","author":"Kretzler","year":"1994","journal-title":"Virchows Arch"},{"key":"key\n\t\t\t\t20170518090812_GFS517C34","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1111\/j.1523-1755.2005.67097.x","article-title":"Pathways to nephron loss starting from glomerular diseases-insights from animal models","volume":"67","author":"Kriz","year":"2005","journal-title":"Kidney Int"}],"container-title":["Nephrology Dialysis Transplantation"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/ndt\/article-pdf\/28\/6\/1407\/12782581\/gfs517.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,8,24]],"date-time":"2017-08-24T08:34:11Z","timestamp":1503563651000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ndt\/article-lookup\/doi\/10.1093\/ndt\/gfs517"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,12,9]]},"references-count":34,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2012,12,9]]},"published-print":{"date-parts":[[2013,6]]}},"URL":"https:\/\/doi.org\/10.1093\/ndt\/gfs517","relation":{},"ISSN":["1460-2385","0931-0509"],"issn-type":[{"value":"1460-2385","type":"electronic"},{"value":"0931-0509","type":"print"}],"subject":[],"published":{"date-parts":[[2012,12,9]]}}}