{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,24]],"date-time":"2026-04-24T17:02:10Z","timestamp":1777050130581,"version":"3.51.4"},"reference-count":24,"publisher":"Oxford University Press (OUP)","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"\n Background<\/jats:title>\n The creation of arteriovenous fistula (AVF) may retard chronic kidney disease progression in the general population. Conversely, the impact of AVF closure on renal function in kidney transplant recipients (KTRs) remains unknown.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n From 2007 to 2013, we retrospectively categorized 285 KTRs into three groups: no AVF (Group 0, n = 90), closed AVF (Group 1, n = 114) and left-open AVF (Group 2, n = 81). AVF closure occurred at 653 \u00b1 441 days after kidney transplantation (KTx), with a thrombosis:ligation ratio of 19:95. Estimated glomerular filtration rate (eGFR) was determined using the Modification of Diet in Renal Disease equation. Linear mixed models calculated the slope and intercept of eGFR decline versus time, starting at 3 months post-KTx, with a median follow-up of 1807 days (95% confidence interval 1665\u20132028).<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n The eGFR slope was less in Group 1 (\u22120.081 mL\/min\/month) compared with Group 0 (\u22120.183 mL\/min\/month; P = 0.03) or Group 2 (\u22120.164 mL\/min\/month; P = 0.09). Still, the eGFR slope significantly deteriorated after (\u22120.159 mL\/min\/month) versus before (0.038 mL\/min\/month) AVF closure (P = 0.03). Study periods before versus after AVF closure were balanced to a mean of 13.5 and 12.5 months, respectively, with at least 10 observations per patient (n = 99).<\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n In conclusion, a significant acceleration of eGFR decline is observed over the 12 months following the closure of a functioning AVF in KTRs.<\/jats:p>\n <\/jats:sec>","DOI":"10.1093\/ndt\/gfw351","type":"journal-article","created":{"date-parts":[[2016,10,18]],"date-time":"2016-10-18T16:20:33Z","timestamp":1476807633000},"source":"Crossref","is-referenced-by-count":14,"title":["The closure of arteriovenous fistula in kidney transplant recipients is associated with an acceleration of kidney function decline"],"prefix":"10.1093","author":[{"given":"Laurent","family":"Weekers","sequence":"first","affiliation":[{"name":"1 Division of Nephrology, Department of Internal Medicine, University of Li\u00e8ge Hospital (ULg CHU), Li\u00e8ge, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pauline","family":"Vanderweckene","sequence":"additional","affiliation":[{"name":"1 Division of Nephrology, Department of Internal Medicine, University of Li\u00e8ge Hospital (ULg CHU), Li\u00e8ge, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hans","family":"Pottel","sequence":"additional","affiliation":[{"name":"2 KU Leuven Kulak, Department of Public Health and Primary Care, University of Leuven, Kortrijk, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diego","family":"Castanares-Zapatero","sequence":"additional","affiliation":[{"name":"3 Intensive Care Unit, Cliniques universistaires Saint-Luc, Universit\u00e9 catholique de Louvain, Brussels, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Catherine","family":"Bonvoisin","sequence":"additional","affiliation":[{"name":"1 Division of Nephrology, Department of Internal Medicine, University of Li\u00e8ge Hospital (ULg CHU), Li\u00e8ge, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Etienne","family":"Hamoir","sequence":"additional","affiliation":[{"name":"4 Division of Abdominal Surgery and Transplantation, Department of Surgery, University of Li\u00e8ge Hospital (ULg CHU), Li\u00e8ge, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sylvie","family":"Maweja","sequence":"additional","affiliation":[{"name":"4 Division of Abdominal Surgery and Transplantation, Department of Surgery, University of Li\u00e8ge Hospital (ULg CHU), Li\u00e8ge, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean-Marie","family":"Krzesinski","sequence":"additional","affiliation":[{"name":"1 Division of Nephrology, Department of Internal Medicine, University of Li\u00e8ge Hospital (ULg CHU), Li\u00e8ge, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pierre","family":"Delanaye","sequence":"additional","affiliation":[{"name":"1 Division of Nephrology, Department of Internal Medicine, University of Li\u00e8ge Hospital (ULg CHU), Li\u00e8ge, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fran\u00e7ois","family":"Jouret","sequence":"additional","affiliation":[{"name":"1 Division of Nephrology, Department of Internal Medicine, University of Li\u00e8ge Hospital (ULg CHU), Li\u00e8ge, Belgium"},{"name":"5 Groupe Interdisciplinaire de G\u00e9noprot\u00e9omique Appliqu\u00e9e (GIGA), Cardiovascular Sciences, University of Li\u00e8ge, Li\u00e8ge, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2016,10,17]]},"reference":[{"issue":"4 Suppl 3","key":"2025102312475293800_GFW351C1","first-page":"S150","article-title":"National Kidney Foundation-Dialysis Outcomes Quality Initiative","volume":"30","author":"NKF-DOQI clinical practice guidelines for vascular access","year":"1997","journal-title":"Am J Kidney Dis"},{"key":"2025102312475293800_GFW351C2","first-page":"159","article-title":"Hemodialysis arteriovenous fistula after transplant: to keep or not to keep?","volume":"6","author":"Einollahi","year":"2012","journal-title":"Iran J Kidney Dis"},{"key":"2025102312475293800_GFW351C3","doi-asserted-by":"crossref","first-page":"4006","DOI":"10.1016\/j.transproceed.2010.09.057","article-title":"Functional status of hemodialysis arteriovenous fistula in kidney transplant recipients as a predictor of allograft function and survival","volume":"42","author":"Vajdic","year":"2010","journal-title":"Transplant Proc"},{"key":"2025102312475293800_GFW351C4","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1097\/00007890-200207150-00013","article-title":"Reduction of left ventricular diameter and mass after surgical arteriovenous fistula closure in renal transplant recipients","volume":"74","author":"Unger","year":"2002","journal-title":"Transplantation"},{"key":"2025102312475293800_GFW351C5","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1097\/TP.0b013e318160f163","article-title":"Arteriovenous fistula closure after renal transplantation: a prospective study with 24-hour ambulatory blood pressure monitoring","volume":"85","author":"Unger","year":"2008","journal-title":"Transplantation"},{"key":"2025102312475293800_GFW351C6","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1093\/ndt\/16.2.368","article-title":"Effect of closure of the arteriovenous fistula on left ventricular dimensions in renal transplant patients","volume":"16","author":"van Duijnhoven","year":"2001","journal-title":"Nephrol Dial Transplant"},{"key":"2025102312475293800_GFW351C7","doi-asserted-by":"crossref","first-page":"348","DOI":"10.20452\/pamw.1349","article-title":"To close or not to close: fistula ligation and cardiac function in kidney allograft recipients","volume":"122","author":"Glowinski","year":"2012","journal-title":"Pol Arch Med Wewn"},{"key":"2025102312475293800_GFW351C8","first-page":"198","article-title":"Impact of dialysis access fistula on cardiac function after kidney transplantation","volume":"6","author":"Soleimani","year":"2012","journal-title":"Iran J Kidney Dis"},{"key":"2025102312475293800_GFW351C9","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1159\/000006980","article-title":"Cardiac effects of persistent hemodialysis arteriovenous access in recipients of renal allograft","volume":"92","author":"De Lima","year":"1999","journal-title":"Cardiology"},{"key":"2025102312475293800_GFW351C10","doi-asserted-by":"crossref","first-page":"2014","DOI":"10.1093\/ndt\/gfv082","article-title":"Arteriovenous fistula creation may slow estimated glomerular filtration rate trajectory","volume":"30","author":"Golper","year":"2015","journal-title":"Nephrol Dial Transplant"},{"key":"2025102312475293800_GFW351C11","doi-asserted-by":"crossref","DOI":"10.1093\/ndt\/gfw220","article-title":"Association between vascular access creation and deceleration of estimated glomerular filtration rate decline in late-stage chronic kidney disease patients transitioning to end-stage renal disease","author":"Sumida","year":"2016","journal-title":"Nephrol Dial Transplant"},{"key":"2025102312475293800_GFW351C12","doi-asserted-by":"crossref","first-page":"1939","DOI":"10.1093\/ndt\/gfv281","article-title":"Arteriovenous fistula as a nephroprotective intervention in advanced CKD: scientific discovery and explanation, and the evaluation of interventions","volume":"30","author":"Locatelli","year":"2015","journal-title":"Nephrol Dial Transplant"},{"key":"2025102312475293800_GFW351C13","doi-asserted-by":"crossref","first-page":"3296","DOI":"10.1093\/ndt\/gfq851","article-title":"Effects of arteriovenous fistula formation on arterial stiffness and cardiovascular performance and function","volume":"26","author":"Korsheed","year":"2011","journal-title":"Nephrol Dial Transplant"},{"key":"2025102312475293800_GFW351C14","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1373\/clinchem.2006.077180","article-title":"Expressing the Modification of Diet in Renal Disease Study equation for estimating glomerular filtration rate with standardized serum creatinine values","volume":"53","author":"Levey","year":"2007","journal-title":"Clin Chem"},{"key":"2025102312475293800_GFW351C15","doi-asserted-by":"crossref","first-page":"1211","DOI":"10.1097\/TP.0b013e318288caa6","article-title":"MDRD versus CKD-EPI equation to estimate glomerular filtration rate in kidney transplant recipients","volume":"95","author":"Masson","year":"2013","journal-title":"Transplantation"},{"key":"2025102312475293800_GFW351C16","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1046\/j.1523-1755.2002.00407.x","article-title":"Central aortic pressure augmentation in stable renal transplant recipients","volume":"62","author":"Ferro","year":"2002","journal-title":"Kidney Int"},{"key":"2025102312475293800_GFW351C17","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1159\/000176695","article-title":"Changes in left ventricular mass and filling after renal transplantation are related to changes in blood pressure: an echocardiographic and pulsed Doppler study","volume":"85","author":"Peteiro","year":"1994","journal-title":"Cardiology"},{"key":"2025102312475293800_GFW351C18","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1111\/sdi.12366","article-title":"Complications of a high-flow access and its management","volume":"28","author":"Sequeira","year":"2015","journal-title":"Semin Dial"},{"key":"2025102312475293800_GFW351C19","doi-asserted-by":"crossref","first-page":"880","DOI":"10.1111\/j.1600-6143.2006.01690.x","article-title":"Assessment of changes in kidney allograft function using creatinine-based estimates of glomerular filtration rate","volume":"7","author":"Gera","year":"2007","journal-title":"Am J Transplant"},{"key":"2025102312475293800_GFW351C20","doi-asserted-by":"crossref","first-page":"3593","DOI":"10.1093\/ndt\/gfp431","article-title":"Errors induced by indexing glomerular filtration rate for body surface area: reductio ad absurdum","volume":"24","author":"Delanaye","year":"2009","journal-title":"Nephrol Dial Transplant"},{"key":"2025102312475293800_GFW351C21","doi-asserted-by":"crossref","first-page":"1517","DOI":"10.1681\/ASN.2010121321","article-title":"GFR normalized to total body water allows comparisons across genders and body sizes","volume":"22","author":"Eriksen","year":"2011","journal-title":"J Am Soc Nephrol"},{"key":"2025102312475293800_GFW351C22","doi-asserted-by":"crossref","first-page":"1634","DOI":"10.1016\/S0140-6736(14)62053-5","article-title":"Central arteriovenous anastomosis for the treatment of patients with uncontrolled hypertension (the ROX CONTROL HTN study): a randomised controlled trial","volume":"385","author":"Lobo","year":"2015","journal-title":"Lancet"},{"key":"2025102312475293800_GFW351C23","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1161\/HYPERTENSIONAHA.114.02925","article-title":"Arteriovenous anastomosis: is this the way to control hypertension?","volume":"64","author":"Burchell","year":"2014","journal-title":"Hypertension"},{"key":"2025102312475293800_GFW351C24","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1159\/000353708","article-title":"Creation of an arteriovenous fistula is associated with significant acute local and systemic changes in microvascular function","volume":"123","author":"Korsheed","year":"2013","journal-title":"Nephron Clin Pract"}],"container-title":["Nephrology Dialysis Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/ndt\/article-pdf\/32\/1\/196\/9675199\/gfw351.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ndt\/article-pdf\/32\/1\/196\/9675199\/gfw351.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,23]],"date-time":"2025-10-23T16:48:11Z","timestamp":1761238091000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ndt\/article\/32\/1\/196\/2327318"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,10,17]]},"references-count":24,"URL":"https:\/\/doi.org\/10.1093\/ndt\/gfw351","relation":{},"ISSN":["0931-0509","1460-2385"],"issn-type":[{"value":"0931-0509","type":"print"},{"value":"1460-2385","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,10,17]]},"article-number":"gfw351"}}