{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,7]],"date-time":"2026-11-07T00:21:27Z","timestamp":1794010887342,"version":"4.8.0"},"reference-count":78,"publisher":"Oxford University Press (OUP)","issue":"2","funder":[{"DOI":"10.13039\/100009519","name":"Ottawa Hospital Research Institute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009519","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009519","name":"OHRI","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009519","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018,2,1]]},"DOI":"10.1093\/ndt\/gfw470","type":"journal-article","created":{"date-parts":[[2018,2,1]],"date-time":"2018-02-01T10:35:20Z","timestamp":1517481320000},"page":"331-342","source":"Crossref","is-referenced-by-count":151,"title":["The association between proton pump inhibitor use and the risk of adverse kidney outcomes: a systematic review and meta-analysis"],"prefix":"10.1093","volume":"33","author":[{"given":"Surapon","family":"Nochaiwong","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chidchanok","family":"Ruengorn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ratanaporn","family":"Awiphan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kiatkriangkrai","family":"Koyratkoson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chayutthaphong","family":"Chaisai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kajohnsak","family":"Noppakun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wilaiwan","family":"Chongruksut","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kednapa","family":"Thavorn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2017,2,23]]},"reference":[{"key":"key\n\t\t\t\t20180205035631_gfw470-B1","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1503\/cmaj.150570","article-title":"Potential harms of proton pump inhibitor therapy: rare adverse effects of commonly used drugs","volume":"188","author":"Benmassaoud","year":"2016","journal-title":"CMAJ"},{"key":"key\n\t\t\t\t20180205035631_gfw470-B2","doi-asserted-by":"crossref","first-page":"154","DOI":"10.3109\/02813432.2010.493315","article-title":"Use of proton-pump inhibitors and their associated risks among frail elderly nursing home residents","volume":"28","author":"Teramura-Gronblad","year":"2010","journal-title":"Scand J Prim Health Care"},{"key":"key\n\t\t\t\t20180205035631_gfw470-B3","doi-asserted-by":"crossref","first-page":"652","DOI":"10.1111\/j.1365-2036.2009.04085.x","article-title":"Therapeutic intent of proton pump inhibitor prescription among elderly nonsteroidal anti-inflammatory drug users","volume":"30","author":"Dries","year":"2009","journal-title":"Aliment Pharmacol Ther"},{"key":"key\n\t\t\t\t20180205035631_gfw470-B4","doi-asserted-by":"crossref","first-page":"1019","DOI":"10.1002\/pds.1969","article-title":"Marked increase in proton pump inhibitors use in Australia","volume":"19","author":"Hollingworth","year":"2010","journal-title":"Pharmacoepidemiol Drug Saf"},{"key":"key\n\t\t\t\t20180205035631_gfw470-B5","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1111\/apt.13649","article-title":"Medical and non-medical predictors of initiating long-term use of proton pump inhibitors: a nationwide cohort study of first-time users during a 10-year period","volume":"44","author":"Haastrup","year":"2016","journal-title":"Aliment Pharmacol Ther"},{"key":"key\n\t\t\t\t20180205035631_gfw470-B6","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1177\/1756283X12437358","article-title":"Overutilization of proton-pump inhibitors: what the clinician needs to know","volume":"5","author":"Heidelbaugh","year":"2012","journal-title":"Therap Adv Gastroenterol"},{"key":"key\n\t\t\t\t20180205035631_gfw470-B7","first-page":"235","article-title":"Potential effects of rational prescribing on national health care spending: more than half a billion dollars in annual savings","volume":"62","author":"Littman","year":"2016","journal-title":"Can Fam Physician"},{"key":"key\n\t\t\t\t20180205035631_gfw470-B8","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1159\/000235953","article-title":"Management of reflux symptoms with over-the-counter proton pump inhibitors: issues and proposed guidelines","volume":"80","author":"Haag","year":"2009","journal-title":"Digestion"},{"key":"key\n\t\t\t\t20180205035631_gfw470-B9","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1038\/ajg.2013.421","article-title":"Consumer use of over-the-counter proton pump inhibitors in patients with gastroesophageal reflux disease","volume":"109","author":"Sheikh","year":"2014","journal-title":"Am J Gastroenterol"},{"key":"key\n\t\t\t\t20180205035631_gfw470-B10","doi-asserted-by":"crossref","first-page":"1856","DOI":"10.1001\/jamainternmed.2014.2900","article-title":"National use of proton pump inhibitors from 2007 to 2011","volume":"174","author":"Johansen","year":"2014","journal-title":"JAMA Intern Med"},{"key":"key\n\t\t\t\t20180205035631_gfw470-B11","doi-asserted-by":"crossref","first-page":"1265","DOI":"10.1007\/s00228-010-0871-9","article-title":"Appropriateness of treatment recommendations for PPI in hospital discharge letters","volume":"66","author":"Ahrens","year":"2010","journal-title":"Eur J Clin Pharmacol"},{"key":"key\n\t\t\t\t20180205035631_gfw470-B12","first-page":"e228","article-title":"Magnitude and economic effect of overuse of antisecretory therapy in the ambulatory care setting","volume":"16","author":"Heidelbaugh","year":"2010","journal-title":"Am J Manag Care"},{"key":"key\n\t\t\t\t20180205035631_gfw470-B13","doi-asserted-by":"crossref","first-page":"e0141779","DOI":"10.1371\/journal.pone.0141779","article-title":"Multimorbidities and overprescription of proton pump inhibitors in older patients","volume":"10","author":"Delcher","year":"2015","journal-title":"PLoS One"},{"key":"key\n\t\t\t\t20180205035631_gfw470-B14","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1007\/s40266-014-0166-4","article-title":"A benefit-risk assessment of the use of proton pump inhibitors in the elderly","volume":"31","author":"Masclee","year":"2014","journal-title":"Drugs Aging"},{"key":"key\n\t\t\t\t20180205035631_gfw470-B15","first-page":"S491","article-title":"A critical evaluation of proton pump inhibitors in the treatment of gastroesophageal reflux disease","volume":"6(Suppl 9)","author":"Berardi","year":"2000","journal-title":"Am J Manag Care"},{"key":"key\n\t\t\t\t20180205035631_gfw470-B16","year":"2016"},{"key":"key\n\t\t\t\t20180205035631_gfw470-B17","year":"2013"},{"key":"key\n\t\t\t\t20180205035631_gfw470-B18","year":"2012"},{"key":"key\n\t\t\t\t20180205035631_gfw470-B19","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1001\/jamainternmed.2015.7927","article-title":"Adverse effects associated with proton pump inhibitors","volume":"176","author":"Schoenfeld","year":"2016","journal-title":"JAMA Intern Med"},{"key":"key\n\t\t\t\t20180205035631_gfw470-B20","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1111\/jgh.12065","article-title":"Acid-suppressive therapy is associated with spontaneous bacterial peritonitis in cirrhotic patients: a meta-analysis","volume":"28","author":"Deshpande","year":"2013","journal-title":"J Gastroenterol Hepatol"},{"key":"key\n\t\t\t\t20180205035631_gfw470-B21","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1001\/jamaneurol.2015.4791","article-title":"Association of proton pump inhibitors with risk of dementia: a pharmacoepidemiological claims data analysis","volume":"73","author":"Gomm","year":"2016","journal-title":"JAMA Neurol"},{"key":"key\n\t\t\t\t20180205035631_gfw470-B22","doi-asserted-by":"crossref","first-page":"3428","DOI":"10.1111\/j.1572-0241.2001.05345.x","article-title":"Acute interstitial nephritis due to omeprazole","volume":"96","author":"Myers","year":"2001","journal-title":"Am J Gastroenterol"},{"key":"key\n\t\t\t\t20180205035631_gfw470-B23","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1053\/j.ajkd.2014.04.027","article-title":"Biopsy-proven acute interstitial nephritis, 1993\u20132011: a case series","volume":"64","author":"Muriithi","year":"2014","journal-title":"Am J Kidney Dis"},{"key":"key\n\t\t\t\t20180205035631_gfw470-B24","doi-asserted-by":"crossref","first-page":"1155","DOI":"10.1002\/pds.3329","article-title":"Proton pump inhibitors and traditional nonsteroidal anti-inflammatory drugs and the risk of acute interstitial nephritis and acute kidney injury","volume":"21","author":"Leonard","year":"2012","journal-title":"Pharmacoepidemiol Drug Saf"},{"key":"key\n\t\t\t\t20180205035631_gfw470-B25","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1186\/1471-2369-14-150","article-title":"Proton pump inhibitors and acute kidney injury: a nested case\u2013control study","volume":"14","author":"Klepser","year":"2013","journal-title":"BMC Nephrol"},{"key":"key\n\t\t\t\t20180205035631_gfw470-B26","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1038\/ki.2014.74","article-title":"A nationwide nested case\u2013control study indicates an increased risk of acute interstitial nephritis with proton pump inhibitor use","volume":"86","author":"Blank","year":"2014","journal-title":"Kidney Int"},{"key":"key\n\t\t\t\t20180205035631_gfw470-B27","doi-asserted-by":"crossref","first-page":"E166","DOI":"10.9778\/cmajo.20140074","article-title":"Proton pump inhibitors and the risk of acute kidney injury in older patients: a population-based cohort study","volume":"3","author":"Antoniou","year":"2015","journal-title":"CMAJ Open"},{"key":"key\n\t\t\t\t20180205035631_gfw470-B28","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1186\/s12882-016-0325-4","article-title":"Proton pump inhibitors are associated with increased risk of development of chronic kidney disease","volume":"17","author":"Arora","year":"2016","journal-title":"BMC Nephrol"},{"key":"key\n\t\t\t\t20180205035631_gfw470-B29","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1001\/jamainternmed.2015.7193","article-title":"Proton pump inhibitor use and the risk of chronic kidney disease","volume":"176","author":"Lazarus","year":"2016","journal-title":"JAMA Intern Med"},{"key":"key\n\t\t\t\t20180205035631_gfw470-B30","doi-asserted-by":"crossref","first-page":"3153","DOI":"10.1681\/ASN.2015121377","article-title":"Proton pump inhibitors and risk of incident CKD and progression to ESRD","volume":"27","author":"Xie","year":"2016","journal-title":"J Am Soc Nephrol"},{"key":"key\n\t\t\t\t20180205035631_gfw470-B31","year":"2014"},{"key":"key\n\t\t\t\t20180205035631_gfw470-B32","doi-asserted-by":"crossref","first-page":"2008","DOI":"10.1001\/jama.283.15.2008","article-title":"Meta-analysis of observational studies in epidemiology: a proposal for reporting. Meta-analysis of observational studies in epidemiology (MOOSE) group","volume":"283","author":"Stroup","year":"2000","journal-title":"JAMA"},{"key":"key\n\t\t\t\t20180205035631_gfw470-B33","first-page":"1","article-title":"KDIGO clinical practice guideline for acute kidney injury","volume":"2","author":"Kidney Disease: Improving Global Outcomes (KDIGO) Acute Kidney Injury Work Group","year":"2012","journal-title":"Kidney Int Suppl"},{"key":"key\n\t\t\t\t20180205035631_gfw470-B34","first-page":"1","article-title":"KDIGO 2012 clinical practice guideline for the evaluation and management of chronic kidney disease","volume":"3","author":"Kidney Disease: Improving Global Outcomes (KDIGO) CKD Work Group","year":"2013","journal-title":"Kidney Int Suppl"},{"key":"key\n\t\t\t\t20180205035631_gfw470-B35","author":"Wells"},{"key":"key\n\t\t\t\t20180205035631_gfw470-B36","doi-asserted-by":"crossref","first-page":"1312","DOI":"10.1016\/j.jclinepi.2014.11.023","article-title":"Grading the strength of a body of evidence when assessing health care interventions: an EPC update","volume":"68","author":"Berkman","year":"2015","journal-title":"J Clin Epidemiol"},{"key":"key\n\t\t\t\t20180205035631_gfw470-B37","doi-asserted-by":"crossref","first-page":"iii","DOI":"10.3310\/hta10050","article-title":"Comparison of conference abstracts and presentations with full-text articles in the health technology assessments of rapidly evolving technologies","volume":"10","author":"Dundar","year":"2006","journal-title":"Health Technol Assess"},{"key":"key\n\t\t\t\t20180205035631_gfw470-B38","doi-asserted-by":"crossref","first-page":"1690","DOI":"10.1001\/jama.280.19.1690","article-title":"What\u2019s the relative risk? A method of correcting the odds ratio in cohort studies of common outcomes","volume":"280","author":"Zhang","year":"1998","journal-title":"JAMA"},{"key":"key\n\t\t\t\t20180205035631_gfw470-B39","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/0197-2456(86)90046-2","article-title":"Meta-analysis in clinical trials","volume":"7","author":"DerSimonian","year":"1986","journal-title":"Control Clin Trials"},{"key":"key\n\t\t\t\t20180205035631_gfw470-B40","first-page":"687","article-title":"The ARIC investigators","volume":"129","author":"The Atherosclerosis Risk in Communities (ARIC) Study: design and objectives","year":"1989","journal-title":"Am J Epidemiol"},{"key":"key\n\t\t\t\t20180205035631_gfw470-B41","doi-asserted-by":"crossref","first-page":"15","DOI":"10.2105\/AJPH.88.1.15","article-title":"Use and misuse of population attributable fractions","volume":"88","author":"Rockhill","year":"1998","journal-title":"Am J Public Health"},{"key":"key\n\t\t\t\t20180205035631_gfw470-B42","doi-asserted-by":"crossref","first-page":"1079","DOI":"10.1002\/pds.4043","article-title":"Proton pump inhibitor prescribing patterns in the UK: a primary care database study","volume":"25","author":"Othman","year":"2016","journal-title":"Pharmacoepidemiol Drug Saf"},{"key":"key\n\t\t\t\t20180205035631_gfw470-B43","doi-asserted-by":"crossref","first-page":"1818","DOI":"10.1001\/jama.2015.13766","article-title":"Trends in prescription drug use among adults in the United States from 1999\u20132012","volume":"314","author":"Kantor","year":"2015","journal-title":"JAMA"},{"key":"key\n\t\t\t\t20180205035631_gfw470-B44","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1001\/jamainternmed.2015.8581","article-title":"Changes in prescription and over-the-counter medication and dietary supplement use among older adults in the United States, 2005 vs 2011","volume":"176","author":"Qato","year":"2016","journal-title":"JAMA Intern Med"},{"key":"key\n\t\t\t\t20180205035631_gfw470-B45","doi-asserted-by":"crossref","first-page":"2616","DOI":"10.1016\/S0140-6736(15)60126-X","article-title":"International Society of Nephrology\u2019s 0by25 initiative for acute kidney injury (zero preventable deaths by 2025): a human rights case for nephrology","volume":"385","author":"Mehta","year":"2015","journal-title":"Lancet"},{"key":"key\n\t\t\t\t20180205035631_gfw470-B46","doi-asserted-by":"crossref","first-page":"950","DOI":"10.1038\/ki.2015.230","article-title":"A systematic analysis of worldwide population-based data on the global burden of chronic kidney disease in 2010","volume":"88","author":"Mills","year":"2015","journal-title":"Kidney Int"},{"key":"key\n\t\t\t\t20180205035631_gfw470-B47","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1136\/bmj.327.7414.557","article-title":"Measuring inconsistency in meta-analyses","volume":"327","author":"Higgins","year":"2003","journal-title":"BMJ"},{"key":"key\n\t\t\t\t20180205035631_gfw470-B48","doi-asserted-by":"crossref","first-page":"3336","DOI":"10.1093\/eurheartj\/ehu424","article-title":"Systematic reviews and meta-analyses of randomized trials: principles and pitfalls","volume":"35","author":"da Costa","year":"2014","journal-title":"Eur Heart J"},{"key":"key\n\t\t\t\t20180205035631_gfw470-B49","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1186\/1471-2288-8-79","article-title":"Undue reliance on I(2) in assessing heterogeneity may mislead","volume":"8","author":"Rucker","year":"2008","journal-title":"BMC Med Res Methodol"},{"key":"key\n\t\t\t\t20180205035631_gfw470-B50","doi-asserted-by":"crossref","first-page":"1088","DOI":"10.2307\/2533446","article-title":"Operating characteristics of a rank correlation test for publication bias","volume":"50","author":"Begg","year":"1994","journal-title":"Biometrics"},{"key":"key\n\t\t\t\t20180205035631_gfw470-B51","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1136\/bmj.315.7109.629","article-title":"Bias in meta-analysis detected by a simple, graphical test","volume":"315","author":"Egger","year":"1997","journal-title":"BMJ"},{"key":"key\n\t\t\t\t20180205035631_gfw470-B52","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1111\/j.0006-341X.2000.00455.x","article-title":"Trim and fill: a simple funnel-plot-based method of testing and adjusting for publication bias in meta-analysis","volume":"56","author":"Duval","year":"2000","journal-title":"Biometrics"},{"key":"key\n\t\t\t\t20180205035631_gfw470-B53","doi-asserted-by":"crossref","first-page":"1500","DOI":"10.1002\/jcph.805","article-title":"Proton pump inhibitors are not associated with acute kidney injury in critical illness","volume":"56","author":"Lee","year":"2016","journal-title":"J Clin Pharmacol"},{"key":"key\n\t\t\t\t20180205035631_gfw470-B54","doi-asserted-by":"crossref","first-page":"e3363","DOI":"10.1097\/MD.0000000000003363","article-title":"Association between the use of proton pump inhibitors and the risk of ESRD in renal diseases: a population-based, case\u2013control study","volume":"95","author":"Peng","year":"2016","journal-title":"Medicine (Baltimore)"},{"key":"key\n\t\t\t\t20180205035631_gfw470-B55","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1111\/j.1365-2036.2007.03407.x","article-title":"Systematic review: proton pump inhibitor-associated acute interstitial nephritis","volume":"26","author":"Sierra","year":"2007","journal-title":"Aliment Pharmacol Ther"},{"key":"key\n\t\t\t\t20180205035631_gfw470-B56","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1111\/j.1440-1797.2006.00651.x","article-title":"Proton pump inhibitors and acute interstitial nephritis: report and analysis of 15 cases","volume":"11","author":"Simpson","year":"2006","journal-title":"Nephrology (Carlton)"},{"key":"key\n\t\t\t\t20180205035631_gfw470-B57","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1007\/s40620-016-0309-2","article-title":"PPIs and kidney disease: from AIN to CKD","volume":"29","author":"Moledina","year":"2016","journal-title":"J Nephrol"},{"key":"key\n\t\t\t\t20180205035631_gfw470-B58","doi-asserted-by":"crossref","first-page":"956","DOI":"10.1038\/ki.2010.89","article-title":"Acute interstitial nephritis","volume":"77","author":"Praga","year":"2010","journal-title":"Kidney Int"},{"key":"key\n\t\t\t\t20180205035631_gfw470-B59","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1111\/nep.12226","article-title":"Omeprazole-induced acute interstitial nephritis: a possible Th1\u2013Th17-mediated injury?","volume":"19","author":"Berney-Meyer","year":"2014","journal-title":"Nephrology (Carlton)"},{"key":"key\n\t\t\t\t20180205035631_gfw470-B60","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1038\/nrneph.2010.71","article-title":"Drug-induced acute interstitial nephritis","volume":"6","author":"Perazella","year":"2010","journal-title":"Nat Rev Nephrol"},{"key":"key\n\t\t\t\t20180205035631_gfw470-B61","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1016\/j.cgh.2005.11.004","article-title":"Proton pump inhibitors and acute interstitial nephritis","volume":"4","author":"Geevasinga","year":"2006","journal-title":"Clin Gastroenterol Hepatol"},{"key":"key\n\t\t\t\t20180205035631_gfw470-B62","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1056\/NEJMra1214243","article-title":"Acute kidney injury and chronic kidney disease as interconnected syndromes","volume":"371","author":"Chawla","year":"2014","journal-title":"N Engl J Med"},{"key":"key\n\t\t\t\t20180205035631_gfw470-B63","doi-asserted-by":"crossref","first-page":"742","DOI":"10.1053\/j.ajkd.2015.10.019","article-title":"Acute kidney injury recovery pattern and subsequent risk of CKD: an analysis of veterans health administration data","volume":"67","author":"Heung","year":"2016","journal-title":"Am J Kidney Dis"},{"key":"key\n\t\t\t\t20180205035631_gfw470-B64","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1038\/ki.2011.379","article-title":"Chronic kidney disease after acute kidney injury: a systematic review and meta-analysis","volume":"81","author":"Coca","year":"2012","journal-title":"Kidney Int"},{"key":"key\n\t\t\t\t20180205035631_gfw470-B65","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1038\/nrneph.2012.280","article-title":"Chronic kidney disease following acute kidney injury\u2014risk and outcomes","volume":"9","author":"Leung","year":"2013","journal-title":"Nat Rev Nephrol"},{"key":"key\n\t\t\t\t20180205035631_gfw470-B66","doi-asserted-by":"crossref","first-page":"e36","DOI":"10.1161\/CIRCRESAHA.116.308807","article-title":"Proton pump inhibitors accelerate endothelial senescence","volume":"118","author":"Yepuri","year":"2016","journal-title":"Circ Res"},{"key":"key\n\t\t\t\t20180205035631_gfw470-B67","first-page":"58","article-title":"Magnesium deficiency and endothelial dysfunction: is oxidative stress involved?","volume":"21","author":"Wolf","year":"2008","journal-title":"Magnes Res"},{"key":"key\n\t\t\t\t20180205035631_gfw470-B68","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.abb.2006.03.031","article-title":"Magnesium and the inflammatory response: potential physiopathological implications","volume":"458","author":"Mazur","year":"2007","journal-title":"Arch Biochem Biophys"},{"key":"key\n\t\t\t\t20180205035631_gfw470-B69","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1161\/STROKEAHA.107.490631","article-title":"Overexpression of dimethylarginine dimethylaminohydrolase inhibits asymmetric dimethylarginine-induced endothelial dysfunction in the cerebral circulation","volume":"39","author":"Dayoub","year":"2008","journal-title":"Stroke"},{"key":"key\n\t\t\t\t20180205035631_gfw470-B70","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1161\/CIRCULATIONAHA.113.003602","article-title":"Unexpected effect of proton pump inhibitors: elevation of the cardiovascular risk factor asymmetric dimethylarginine","volume":"128","author":"Ghebremariam","year":"2013","journal-title":"Circulation"},{"key":"key\n\t\t\t\t20180205035631_gfw470-B71","doi-asserted-by":"crossref","first-page":"e0124653","DOI":"10.1371\/journal.pone.0124653","article-title":"Proton pump inhibitor usage and the risk of myocardial infarction in the general population","volume":"10","author":"Shah","year":"2015","journal-title":"PLoS One"},{"key":"key\n\t\t\t\t20180205035631_gfw470-B72","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1136\/bmj.39406.449456.BE","article-title":"Overprescribing proton pump inhibitors","volume":"336","author":"Forgacs","year":"2008","journal-title":"BMJ"},{"key":"key\n\t\t\t\t20180205035631_gfw470-B73","year":"2016"},{"key":"key\n\t\t\t\t20180205035631_gfw470-B74","year":"2015"},{"key":"key\n\t\t\t\t20180205035631_gfw470-B75","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1053\/j.ajkd.2015.02.337","article-title":"A meta-analysis of the association of estimated GFR, albuminuria, age, race, and sex with acute kidney injury","volume":"66","author":"Grams","year":"2015","journal-title":"Am J Kidney Dis"},{"key":"key\n\t\t\t\t20180205035631_gfw470-B76","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1053\/j.ajkd.2015.02.338","article-title":"A meta-analysis of the association of estimated GFR, albuminuria, diabetes mellitus, and hypertension with acute kidney injury","volume":"66","author":"James","year":"2015","journal-title":"Am J Kidney Dis"},{"key":"key\n\t\t\t\t20180205035631_gfw470-B77","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1001\/jama.2015.18202","article-title":"Multinational assessment of accuracy of equations for predicting risk of kidney failure: a meta-analysis","volume":"315","author":"Tangri","year":"2016","journal-title":"JAMA"},{"key":"key\n\t\t\t\t20180205035631_gfw470-B78","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1016\/S0140-6736(13)60687-X","article-title":"Chronic kidney disease: global dimension and perspectives","volume":"382","author":"Jha","year":"2013","journal-title":"Lancet"}],"container-title":["Nephrology Dialysis Transplantation"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/ndt\/article-pdf\/33\/2\/331\/23788890\/gfw470.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,2,5]],"date-time":"2018-02-05T03:56:56Z","timestamp":1517803016000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ndt\/article\/33\/2\/331\/3052311"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,2,23]]},"references-count":78,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2017,2,23]]},"published-print":{"date-parts":[[2018,2,1]]}},"URL":"https:\/\/doi.org\/10.1093\/ndt\/gfw470","relation":{},"ISSN":["0931-0509","1460-2385"],"issn-type":[{"value":"0931-0509","type":"print"},{"value":"1460-2385","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2018,2]]},"published":{"date-parts":[[2017,2,23]]}}}