{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T13:22:15Z","timestamp":1789910535575,"version":"4.0.1"},"reference-count":65,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2017,12,13]],"date-time":"2017-12-13T00:00:00Z","timestamp":1513123200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/about_us\/legal\/notices"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["K08DK089002"],"award-info":[{"award-number":["K08DK089002"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R37HL061795, P01HL048743, U01HL108630 and P50GM107618"],"award-info":[{"award-number":["R37HL061795, P01HL048743, U01HL108630 and P50GM107618"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018,6,1]]},"DOI":"10.1093\/ndt\/gfx304","type":"journal-article","created":{"date-parts":[[2017,9,29]],"date-time":"2017-09-29T19:10:25Z","timestamp":1506712225000},"page":"923-934","source":"Crossref","is-referenced-by-count":47,"title":["Pre-clinical model of severe glutathione peroxidase-3 deficiency and chronic kidney disease results in coronary artery thrombosis and depressed left ventricular function"],"prefix":"10.1093","volume":"33","author":[{"given":"Paul","family":"Pang","sequence":"first","affiliation":[{"name":"Department of Medicine, Baylor College of Medicine, Houston, TX, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Molly","family":"Abbott","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Brigham and Women's Hospital, Boston, MA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Malyun","family":"Abdi","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Brigham and Women's Hospital, Boston, MA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Quynh-Anh","family":"Fucci","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Brigham and Women's Hospital, Boston, MA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nikita","family":"Chauhan","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Brigham and Women's Hospital, Boston, MA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Murti","family":"Mistri","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Brigham and Women's Hospital, Boston, MA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brandon","family":"Proctor","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew","family":"Chin","sequence":"additional","affiliation":[{"name":"Department of Radiology, Geisinger Health System, Danville, PA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bin","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Surgery, 5th Hospital of Wuhan, Wuhan University, Wuhan, Hubei, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenqing","family":"Yin","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Brigham and Women's Hospital, Boston, MA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tzong-Shi","family":"Lu","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Brigham and Women's Hospital, Boston, MA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arvin","family":"Halim","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Brigham and Women's Hospital, Boston, MA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenneth","family":"Lim","sequence":"additional","affiliation":[{"name":"Massachusetts General Hospital, Boston, MA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diane E","family":"Handy","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Brigham and Women's Hospital, Boston, MA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph","family":"Loscalzo","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Brigham and Women's Hospital, Boston, MA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew M","family":"Siedlecki","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Brigham and Women's Hospital, Boston, MA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2017,12,13]]},"reference":[{"key":"key\n\t\t\t\t20180626083921_gfx304-B1","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1023\/A:1018718727634","article-title":"Epidemiology, diagnosis, and management of cardiac disease in chronic renal disease","volume":"10","author":"Sarnak","year":"2000","journal-title":"J Thromb Thrombolysis"},{"key":"key\n\t\t\t\t20180626083921_gfx304-B2","doi-asserted-by":"crossref","first-page":"1782","DOI":"10.1001\/jama.2009.1488","article-title":"Cardiovascular and noncardiovascular mortality among patients starting dialysis","volume":"302","author":"de Jager","year":"2009","journal-title":"JAMA"},{"key":"key\n\t\t\t\t20180626083921_gfx304-B3","doi-asserted-by":"crossref","first-page":"1296","DOI":"10.1056\/NEJMoa041031","article-title":"Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization","volume":"351","author":"Go","year":"2004","journal-title":"N Engl J Med"},{"key":"key\n\t\t\t\t20180626083921_gfx304-B4","doi-asserted-by":"crossref","first-page":"19891","DOI":"10.1155\/2007\/19891","article-title":"Inflammatory marker but not adipokine predicts mortality among long-term hemodialysis patients","volume":"2007","author":"Tsai","year":"2007","journal-title":"Mediators Inflamm"},{"key":"key\n\t\t\t\t20180626083921_gfx304-B5","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1177\/039139880903200103","article-title":"Hemodialysis modality, percentage of body fat, and patient survival","volume":"32","author":"Stosovic","year":"2009","journal-title":"Int J Artif Organs"},{"key":"key\n\t\t\t\t20180626083921_gfx304-B6","doi-asserted-by":"crossref","first-page":"1191","DOI":"10.1681\/ASN.2007040503","article-title":"Systolic dysfunction portends increased mortality among those waiting for renal transplant","volume":"19","author":"de Mattos","year":"2008","journal-title":"J Am Soc Nephrol"},{"key":"key\n\t\t\t\t20180626083921_gfx304-B7","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1038\/sj.ki.5001570","article-title":"Peripheral tissue release of interleukin-6 in patients with chronic kidney diseases: effects of end-stage renal disease and microinflammatory state","volume":"70","author":"Garibotto","year":"2006","journal-title":"Kidney Int"},{"key":"key\n\t\t\t\t20180626083921_gfx304-B8","doi-asserted-by":"crossref","first-page":"419","DOI":"10.5414\/CNP64419","article-title":"Relations of inflammatory markers to lipid levels and autonomic tone in patients with moderate and severe chronic kidney disease and in patients under maintenance hemodialysis","volume":"64","author":"Psychari","year":"2005","journal-title":"Clin Nephrol"},{"key":"key\n\t\t\t\t20180626083921_gfx304-B9","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1046\/j.1523-1755.1998.00981.x","article-title":"Immunologic function and survival in hemodialysis patients","volume":"54","author":"Kimmel","year":"1998","journal-title":"Kidney Int"},{"key":"key\n\t\t\t\t20180626083921_gfx304-B10","doi-asserted-by":"crossref","first-page":"43","DOI":"10.3747\/pdi.2013.00150","article-title":"Decreased circulating klotho levels in patients undergoing dialysis and relationship to oxidative stress and inflammation","volume":"35","author":"Oh","year":"2015","journal-title":"Perit Dial Int"},{"key":"key\n\t\t\t\t20180626083921_gfx304-B11","doi-asserted-by":"crossref","first-page":"800","DOI":"10.1038\/ki.2008.690","article-title":"Uremic cardiac hypertrophy is reversed by rapamycin but not by lowering of blood pressure","volume":"75","author":"Siedlecki","year":"2009","journal-title":"Kidney Int"},{"key":"key\n\t\t\t\t20180626083921_gfx304-B12","doi-asserted-by":"crossref","first-page":"C367","DOI":"10.1152\/ajpcell.1994.266.2.C367","article-title":"Human kidney proximal tubules are the main source of plasma glutathione peroxidase","volume":"266","author":"Avissar","year":"1994","journal-title":"Am J Physiol"},{"key":"key\n\t\t\t\t20180626083921_gfx304-B13","doi-asserted-by":"crossref","first-page":"1963","DOI":"10.1161\/CIRCULATIONAHA.110.000034","article-title":"Glutathione peroxidase-3 deficiency promotes platelet-dependent thrombosis in vivo","volume":"123","author":"Jin","year":"2011","journal-title":"Circulation"},{"key":"key\n\t\t\t\t20180626083921_gfx304-B14","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1161\/01.STR.0000252027.53766.2b","article-title":"Promoter polymorphisms in the plasma glutathione peroxidase (GPx-3) gene: a novel risk factor for arterial ischemic stroke among young adults and children","volume":"38","author":"Voetsch","year":"2007","journal-title":"Stroke"},{"key":"key\n\t\t\t\t20180626083921_gfx304-B15","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1159\/000045293","article-title":"Plasma glutathione peroxidase activity is reduced in haemodialysis patients","volume":"81","author":"Roxborough","year":"1999","journal-title":"Nephron"},{"key":"key\n\t\t\t\t20180626083921_gfx304-B16","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.cca.2015.12.002","article-title":"Association between plasma soluble RAGE and renal function is unaffected by medication usage and enzymatic antioxidants in chronic kidney disease with type 2 diabetes","volume":"453","author":"Wong","year":"2016","journal-title":"Clin Chim Acta"},{"key":"key\n\t\t\t\t20180626083921_gfx304-B17","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1111\/nep.12502","article-title":"Effects of atorvastatin on oxidative stress in chronic kidney disease","volume":"20","author":"Fassett","year":"2015","journal-title":"Nephrology (Carlton)"},{"key":"key\n\t\t\t\t20180626083921_gfx304-B18","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/j.kint.2016.07.037","article-title":"Human vascular progenitor cells derived from renal arteries are endothelial-like and assist in the repair of injured renal capillary networks","volume":"91","author":"Pang","year":"2017","journal-title":"Kidney Int"},{"key":"key\n\t\t\t\t20180626083921_gfx304-B19","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1172\/JCI6713","article-title":"RGS4 causes increased mortality and reduced cardiac hypertrophy in response to pressure overload","volume":"104","author":"Rogers","year":"1999","journal-title":"J Clin Invest"},{"key":"key\n\t\t\t\t20180626083921_gfx304-B20","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1038\/ki.2014.364","article-title":"RGS4 inhibits angiotensin II signaling and macrophage localization during renal reperfusion injury independent of vasospasm","volume":"87","author":"Pang","year":"2015","journal-title":"Kidney Int"},{"key":"key\n\t\t\t\t20180626083921_gfx304-B21","doi-asserted-by":"crossref","first-page":"3993","DOI":"10.1073\/pnas.90.9.3993","article-title":"Missense mutations in the beta-myosin heavy-chain gene cause central core disease in hypertrophic cardiomyopathy","volume":"90","author":"Fananapazir","year":"1993","journal-title":"Proc Natl Acad Sci USA"},{"key":"key\n\t\t\t\t20180626083921_gfx304-B22","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1038\/sj.ejhg.5201980","article-title":"Myofibrillar myopathy with arrhythmogenic right ventricular cardiomyopathy 7: corroboration and narrowing of the critical region on 10q22.3","volume":"16","author":"Kuhl","year":"2008","journal-title":"Eur J Hum Genet"},{"key":"key\n\t\t\t\t20180626083921_gfx304-B23","doi-asserted-by":"crossref","first-page":"2250","DOI":"10.1161\/ATVBAHA.107.149468","article-title":"Association of plasminogen activator inhibitor (PAI)-1 (SERPINE1) SNPs with myocardial infarction, plasma PAI-1, and metabolic parameters: the HIFMECH study","volume":"27","author":"Morange","year":"2007","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"key\n\t\t\t\t20180626083921_gfx304-B24","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1038\/nature06504","article-title":"Macrophage migration inhibitory factor stimulates AMP-activated protein kinase in the ischaemic heart","volume":"451","author":"Miller","year":"2008","journal-title":"Nature"},{"key":"key\n\t\t\t\t20180626083921_gfx304-B25","doi-asserted-by":"crossref","first-page":"1496","DOI":"10.1681\/ASN.2013040359","article-title":"Severe renal mass reduction impairs recovery and promotes fibrosis after AKI","volume":"25","author":"Polichnowski","year":"2014","journal-title":"J Am Soc Nephrol"},{"key":"key\n\t\t\t\t20180626083921_gfx304-B26","doi-asserted-by":"crossref","first-page":"594","DOI":"10.1681\/ASN.V103594","article-title":"Asymmetric dimethylarginine plasma concentrations differ in patients with end-stage renal disease: relationship to treatment method and atherosclerotic disease","volume":"10","author":"Kielstein","year":"1999","journal-title":"J Am Soc Nephrol"},{"key":"key\n\t\t\t\t20180626083921_gfx304-B27","doi-asserted-by":"crossref","first-page":"979","DOI":"10.1172\/JCI118522","article-title":"Decreased platelet inhibition by nitric oxide in two brothers with a history of arterial thrombosis","volume":"97","author":"Freedman","year":"1996","journal-title":"J Clin Invest"},{"key":"key\n\t\t\t\t20180626083921_gfx304-B28","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1172\/JCI119540","article-title":"Nitric oxide released from activated platelets inhibits platelet recruitment","volume":"100","author":"Freedman","year":"1997","journal-title":"J Clin Invest"},{"key":"key\n\t\t\t\t20180626083921_gfx304-B29","doi-asserted-by":"crossref","first-page":"2806","DOI":"10.1093\/ndt\/gfq828","article-title":"Glutathione peroxidase, superoxide dismutase and catalase genotypes and activities and the progression of chronic kidney disease","volume":"26","author":"Crawford","year":"2011","journal-title":"Nephrol DialTransplant"},{"key":"key\n\t\t\t\t20180626083921_gfx304-B30","doi-asserted-by":"crossref","first-page":"1842","DOI":"10.1093\/ndt\/gfv254","article-title":"New insights in molecular mechanisms involved in chronic kidney disease using high-resolution plasma proteome analysis","volume":"30","author":"Glorieux","year":"2015","journal-title":"Nephrol Dial Transplant"},{"key":"key\n\t\t\t\t20180626083921_gfx304-B31","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1681\/ASN.2004070582","article-title":"Reduced agonist-induced endothelium-dependent vasodilation in uremia is attributable to an impairment of vascular nitric oxide","volume":"16","author":"Passauer","year":"2005","journal-title":"J Am Soc Nephrol"},{"key":"key\n\t\t\t\t20180626083921_gfx304-B32","doi-asserted-by":"crossref","first-page":"2747","DOI":"10.1681\/ASN.V12122747","article-title":"Oxidative stress and endothelial function in chronic renal failure","volume":"12","author":"Annuk","year":"2001","journal-title":"J Am Soc Nephrol"},{"key":"key\n\t\t\t\t20180626083921_gfx304-B33","doi-asserted-by":"crossref","first-page":"691","DOI":"10.2215\/CJN.04291007","article-title":"Endothelial dysfunction in patients with chronic kidney disease results from advanced glycation end products (AGE)-mediated inhibition of endothelial nitric oxide synthase through RAGE activation","volume":"3","author":"Linden","year":"2008","journal-title":"Clin J Am Soc Nephrol"},{"key":"key\n\t\t\t\t20180626083921_gfx304-B34","doi-asserted-by":"crossref","first-page":"H2037","DOI":"10.1152\/ajpheart.00400.2010","article-title":"The nitric oxide donor molsidomine rescues cardiac function in rats with chronic kidney disease and cardiac dysfunction","volume":"299","author":"Bongartz","year":"2010","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"key\n\t\t\t\t20180626083921_gfx304-B35","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1046\/j.1525-139X.2003.16048.x","article-title":"Thrombosis in end-stage renal disease","volume":"16","author":"Casserly","year":"2003","journal-title":"Semin Dial"},{"key":"key\n\t\t\t\t20180626083921_gfx304-B36","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1681\/ASN.2007030308","article-title":"Chronic kidney disease increases risk for venous thromboembolism","volume":"19","author":"Wattanakit","year":"2008","journal-title":"J Am Soc Nephrol"},{"key":"key\n\t\t\t\t20180626083921_gfx304-B37","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1586\/eem.09.41","article-title":"Antioxidant enzyme deficiencies and vascular disease","volume":"5","author":"Loscalzo","year":"2010","journal-title":"Expert Rev Endocrinol Metab"},{"key":"key\n\t\t\t\t20180626083921_gfx304-B38","first-page":"158","article-title":"Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase","volume":"70","author":"Paglia","year":"1967","journal-title":"J Lab Clin Med"},{"key":"key\n\t\t\t\t20180626083921_gfx304-B39","doi-asserted-by":"crossref","first-page":"1605","DOI":"10.1056\/NEJMoa030535","article-title":"Glutathione peroxidase 1 activity and cardiovascular events in patients with coronary artery disease","volume":"349","author":"Blankenberg","year":"2003","journal-title":"N Engl J Med"},{"key":"key\n\t\t\t\t20180626083921_gfx304-B40","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1042\/cs0840611","article-title":"Low platelet glutathione peroxidase activity and serum selenium concentration in patients with chronic renal failure: relations to dialysis treatments, diet and cardiovascular complications","volume":"84","author":"Girelli","year":"1993","journal-title":"Clin Sci"},{"key":"key\n\t\t\t\t20180626083921_gfx304-B41","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1006\/mgme.1998.2760","article-title":"Plasma glutathione peroxidase and its relationship to renal proximal tubule function","volume":"65","author":"Whitin","year":"1998","journal-title":"Mol Gen Metab"},{"key":"key\n\t\t\t\t20180626083921_gfx304-B42","doi-asserted-by":"crossref","first-page":"F1244","DOI":"10.1152\/ajprenal.00662.2009","article-title":"Extracellular glutathione peroxidase (Gpx3) binds specifically to basement membranes of mouse renal cortex tubule cells","volume":"298","author":"Olson","year":"2010","journal-title":"Am J Physiol Renal Physiol"},{"key":"key\n\t\t\t\t20180626083921_gfx304-B43","doi-asserted-by":"crossref","first-page":"G32","DOI":"10.1152\/ajpgi.00064.2011","article-title":"Glutathione peroxidase-3 produced by the kidney binds to a population of basement membranes in the gastrointestinal tract and in other tissues","volume":"301","author":"Burk","year":"2011","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"key":"key\n\t\t\t\t20180626083921_gfx304-B44","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1089\/ars.2011.3997","article-title":"High-resolution imaging of selenium in kidneys: a localized selenium pool associated with glutathione peroxidase 3","volume":"16","author":"Malinouski","year":"2012","journal-title":"Antioxid Redox Signal"},{"key":"key\n\t\t\t\t20180626083921_gfx304-B45","doi-asserted-by":"crossref","first-page":"2478","DOI":"10.1161\/hc4501.098930","article-title":"Intraplatelet tetrahydrobiopterin plays an important role in regulating canine coronary arterial thrombosis by modulating intraplatelet nitric oxide and superoxide generation","volume":"104","author":"Kanaya","year":"2001","journal-title":"Circulation"},{"key":"key\n\t\t\t\t20180626083921_gfx304-B46","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1213\/01.ANE.0000116930.28250.15","article-title":"Platelet activity in washed platelet concentrates","volume":"99","author":"Schoenfeld","year":"2004","journal-title":"Anesth Analg"},{"key":"key\n\t\t\t\t20180626083921_gfx304-B47","doi-asserted-by":"crossref","first-page":"1142","DOI":"10.1093\/eurheartj\/ehp061","article-title":"Association of plasma asymmetrical dimethylarginine (ADMA) with elevated vascular superoxide production and endothelial nitric oxide synthase uncoupling: implications for endothelial function in human atherosclerosis","volume":"30","author":"Antoniades","year":"2009","journal-title":"Eur Heart J"},{"key":"key\n\t\t\t\t20180626083921_gfx304-B48","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1016\/0140-6736(92)90865-Z","article-title":"Accumulation of an endogenous inhibitor of nitric oxide synthesis in chronic renal failure","volume":"339","author":"Vallance","year":"1992","journal-title":"Lancet"},{"key":"key\n\t\t\t\t20180626083921_gfx304-B49","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1681\/ASN.V131170","article-title":"Marked increase of asymmetric dimethylarginine in patients with incipient primary chronic renal disease","volume":"13","author":"Kielstein","year":"2002","journal-title":"J Am Soc Nephrol"},{"key":"key\n\t\t\t\t20180626083921_gfx304-B50","doi-asserted-by":"crossref","first-page":"e36056","DOI":"10.1371\/journal.pone.0036056","article-title":"Mechanisms of endothelial dysfunction in resistance arteries from patients with end-stage renal disease","volume":"7","author":"Luksha","year":"2012","journal-title":"PLoS One"},{"key":"key\n\t\t\t\t20180626083921_gfx304-B51","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/j.jash.2015.11.008","article-title":"Low urinary citrulline\/arginine ratio associated with blood pressure abnormalities and arterial stiffness in childhood chronic kidney disease","volume":"10","author":"Lin","year":"2016","journal-title":"J Am Soc Hypertens"},{"key":"key\n\t\t\t\t20180626083921_gfx304-B52","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1016\/j.clinbiochem.2011.03.024","article-title":"Arginine\/asymmetric dimethylarginine ratio and cardiovascular risk factors in patients with predialytic chronic kidney disease","volume":"44","author":"Hov","year":"2011","journal-title":"Clin Biochem"},{"key":"key\n\t\t\t\t20180626083921_gfx304-B53","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1038\/ncpneph0143","article-title":"Arginine, arginine analogs and nitric oxide production in chronic kidney disease","volume":"2","author":"Baylis","year":"2006","journal-title":"Nat Clin Pract Nephrol"},{"key":"key\n\t\t\t\t20180626083921_gfx304-B54","doi-asserted-by":"crossref","first-page":"1841","DOI":"10.1007\/s00216-012-5929-3","article-title":"Protein-bound uremic toxins in hemodialysis patients measured by liquid chromatography\/tandem mass spectrometry and their effects on endothelial ROS production","volume":"403","author":"Itoh","year":"2012","journal-title":"Anal Bioanal Chem"},{"key":"key\n\t\t\t\t20180626083921_gfx304-B55","doi-asserted-by":"crossref","first-page":"1163","DOI":"10.1001\/jama.298.10.1163","article-title":"Effect of homocysteine lowering on mortality and vascular disease in advanced chronic kidney disease and end-stage renal disease: a randomized controlled trial","volume":"298","author":"Jamison","year":"2007","journal-title":"JAMA"},{"key":"key\n\t\t\t\t20180626083921_gfx304-B56","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1161\/hh0801.089861","article-title":"Nitric oxide insufficiency, platelet activation, and arterial thrombosis","volume":"88","author":"Loscalzo","year":"2001","journal-title":"Circ Res"},{"key":"key\n\t\t\t\t20180626083921_gfx304-B57","doi-asserted-by":"crossref","first-page":"14368","DOI":"10.1074\/jbc.274.20.14368","article-title":"Nitric oxide inhibits thrombin receptor-activating peptide-induced phosphoinositide 3-kinase activity in human platelets","volume":"274","author":"Pigazzi","year":"1999","journal-title":"J Biol Chem"},{"key":"key\n\t\t\t\t20180626083921_gfx304-B58","doi-asserted-by":"crossref","first-page":"888","DOI":"10.1016\/j.ejheart.2004.12.012","article-title":"Hypotension is associated with diuretic resistance in severe chronic heart failure, independent of renal function","volume":"7","author":"De Pasquale","year":"2005","journal-title":"Eur J Heart Fail"},{"key":"key\n\t\t\t\t20180626083921_gfx304-B59","doi-asserted-by":"crossref","first-page":"918","DOI":"10.1161\/CIRCHEARTFAILURE.113.000872","article-title":"Hypotension during hospitalization for acute heart failure is independently associated with 30-day mortality: findings from ASCEND-HF","volume":"7","author":"Patel","year":"2014","journal-title":"Circ Heart Fail"},{"key":"key\n\t\t\t\t20180626083921_gfx304-B60","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1002\/ejhf.260","article-title":"Clinical picture and risk prediction of short-term mortality in cardiogenic shock","volume":"17","author":"Harjola","year":"2015","journal-title":"Eur J Heart Fail"},{"key":"key\n\t\t\t\t20180626083921_gfx304-B61","doi-asserted-by":"crossref","first-page":"2220","DOI":"10.1097\/HJH.0b013e32830ef5e4","article-title":"Oxidative stress after uninephrectomy alters heart morphology in the apolipoprotein E -\/- mouse","volume":"26","author":"Piecha","year":"2008","journal-title":"J Hypertens"},{"key":"key\n\t\t\t\t20180626083921_gfx304-B62","doi-asserted-by":"crossref","first-page":"780","DOI":"10.1016\/S0272-6386(97)90082-2","article-title":"Relationship between left ventricular hypertrophy, myocardial contractility, and load conditions in hemodialysis patients: an echocardiographic study","volume":"30","author":"Dahan","year":"1997","journal-title":"Am J Kidney Dis"},{"key":"key\n\t\t\t\t20180626083921_gfx304-B63","doi-asserted-by":"crossref","first-page":"1290","DOI":"10.1681\/ASN.2014050465","article-title":"Klotho and phosphate are modulators of pathologic uremic cardiac remodeling","volume":"26","author":"Hu","year":"2015","journal-title":"J Am Soc Nephrol"},{"key":"key\n\t\t\t\t20180626083921_gfx304-B64","doi-asserted-by":"crossref","first-page":"2221","DOI":"10.1016\/j.jacc.2004.09.005","article-title":"Induction and reversal of cardiac phenotype of human hypertrophic cardiomyopathy mutation cardiac troponin T-Q92 in switch on-switch off bigenic mice","volume":"44","author":"Lutucuta","year":"2004","journal-title":"J Am Coll Cardiol"},{"key":"key\n\t\t\t\t20180626083921_gfx304-B65","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.numecd.2009.07.006","article-title":"Moderate consumption of red wine, but not gin, decreases erythrocyte superoxide dismutase activity: a randomised cross-over trial","volume":"21","author":"Estruch","year":"2011","journal-title":"Nutr Metab Cardiovasc Dis"}],"container-title":["Nephrology Dialysis Transplantation"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/ndt\/article-pdf\/33\/6\/923\/25093268\/gfx304.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,8,3]],"date-time":"2022-08-03T19:36:12Z","timestamp":1659555372000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ndt\/article\/33\/6\/923\/4735319"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,12,13]]},"references-count":65,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2017,12,13]]},"published-print":{"date-parts":[[2018,6,1]]}},"URL":"https:\/\/doi.org\/10.1093\/ndt\/gfx304","relation":{},"ISSN":["0931-0509","1460-2385"],"issn-type":[{"value":"0931-0509","type":"print"},{"value":"1460-2385","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2018,6]]},"published":{"date-parts":[[2017,12,13]]}}}