{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T19:49:15Z","timestamp":1793735355289,"version":"4.6.1"},"reference-count":50,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2018,2,17]],"date-time":"2018-02-17T00:00:00Z","timestamp":1518825600000},"content-version":"vor","delay-in-days":1,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"H4KH Foundation"},{"DOI":"10.13039\/501100004063","name":"Knut and Alice Wallenberg Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004063","id-type":"DOI","asserted-by":"publisher"}]},{"name":"G\u00f6ran Gustafsson Foundation"},{"name":"Swedish Heart- and Lung Foundation"},{"DOI":"10.13039\/501100004359","name":"Swedish Research Council","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004359","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010663","name":"European Research Council","doi-asserted-by":"publisher","award":["StG282255"],"award-info":[{"award-number":["StG282255"]}],"id":[{"id":"10.13039\/100010663","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100009708","name":"Novo Nordisk Foundation","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100009708","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100009780","name":"Region Sk\u00e5ne","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100009780","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100011077","name":"Sk\u00e5ne University Hospital","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100011077","id-type":"DOI","asserted-by":"crossref"}]},{"name":"ALF-funds"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,1,1]]},"DOI":"10.1093\/ndt\/gfy017","type":"journal-article","created":{"date-parts":[[2018,1,14]],"date-time":"2018-01-14T20:07:20Z","timestamp":1515960440000},"page":"74-82","source":"Crossref","is-referenced-by-count":28,"title":["Plasma copeptin as a predictor of kidney disease"],"prefix":"10.1093","volume":"34","author":[{"given":"Sofia","family":"Enh\u00f6rning","sequence":"first","affiliation":[{"name":"Department of Endocrinology, Sk\u00e5ne University Hospital, Lund, Sweden"},{"name":"Department of Clinical Sciences, Lund University, Malm\u00f6, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anders","family":"Christensson","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences, Lund University, Malm\u00f6, Sweden"},{"name":"Department of Nephrology, Sk\u00e5ne University Hospital, Lund, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olle","family":"Melander","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences, Lund University, Malm\u00f6, Sweden"},{"name":"Department of Internal Medicine, Sk\u00e5ne University Hospital, Lund, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2018,2,16]]},"reference":[{"key":"key\n\t\t\t\t2019010709180960700_gfy017-B1","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1016\/S0140-6736(13)60687-X","article-title":"Chronic kidney disease: global dimension and perspectives","volume":"382","author":"Jha","year":"2013","journal-title":"Lancet"},{"key":"key\n\t\t\t\t2019010709180960700_gfy017-B2","doi-asserted-by":"crossref","first-page":"1296","DOI":"10.1056\/NEJMoa041031","article-title":"Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization","volume":"351","author":"Go","year":"2004","journal-title":"N Engl J Med"},{"key":"key\n\t\t\t\t2019010709180960700_gfy017-B3","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1146\/annurev.ph.43.030181.003143","article-title":"Antidiuretic hormone","volume":"43","author":"Handler","year":"1981","journal-title":"Annu Rev Physiol"},{"key":"key\n\t\t\t\t2019010709180960700_gfy017-B4","doi-asserted-by":"crossref","first-page":"2763","DOI":"10.1172\/JCI118731","article-title":"Rat renal arcade segment expresses vasopressin-regulated water channel and vasopressin V2 receptor","volume":"97","author":"Kishore","year":"1996","journal-title":"J Clin Invest"},{"key":"key\n\t\t\t\t2019010709180960700_gfy017-B5","doi-asserted-by":"crossref","first-page":"2102","DOI":"10.1161\/CIRCULATIONAHA.109.909663","article-title":"Plasma copeptin and the risk of diabetes mellitus","volume":"121","author":"Enhorning","year":"2010","journal-title":"Circulation"},{"key":"key\n\t\t\t\t2019010709180960700_gfy017-B6","doi-asserted-by":"crossref","first-page":"1963","DOI":"10.1007\/s00125-012-2545-x","article-title":"Sex differences in the association between plasma copeptin and incident type 2 diabetes: the Prevention of Renal and Vascular Endstage Disease (PREVEND) study","volume":"55","author":"Abbasi","year":"2012","journal-title":"Diabetologia"},{"key":"key\n\t\t\t\t2019010709180960700_gfy017-B7","doi-asserted-by":"crossref","first-page":"E1065","DOI":"10.1210\/jc.2010-2981","article-title":"Plasma copeptin, a unifying factor behind the metabolic syndrome","volume":"96","author":"Enhorning","year":"2011","journal-title":"J Clin Endocrinol Metab"},{"key":"key\n\t\t\t\t2019010709180960700_gfy017-B8","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1038\/ijo.2012.88","article-title":"Copeptin, a marker of vasopressin, in abdominal obesity, diabetes and microalbuminuria: the prospective Malmo Diet and Cancer Study cardiovascular cohort","volume":"37","author":"Enhorning","year":"2013","journal-title":"Int J Obes"},{"key":"key\n\t\t\t\t2019010709180960700_gfy017-B9","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1016\/j.ahj.2014.11.020","article-title":"Copeptin is an independent predictor of diabetic heart disease and death","volume":"169","author":"Enhorning","year":"2015","journal-title":"Am Heart J"},{"key":"key\n\t\t\t\t2019010709180960700_gfy017-B10","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1136\/heartjnl-2015-308183","article-title":"Copeptin predicts coronary artery disease cardiovascular and total mortality","volume":"102","author":"Tasevska","year":"2016","journal-title":"Heart"},{"key":"key\n\t\t\t\t2019010709180960700_gfy017-B11","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1016\/S0022-3565(25)23348-1","article-title":"Human vascular vasopressin receptors: analysis with selective vasopressin receptor antagonists","volume":"239","author":"Ohlstein","year":"1986","journal-title":"J Pharmacol Exp Ther"},{"key":"key\n\t\t\t\t2019010709180960700_gfy017-B12","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/0049-3848(87)90252-0","article-title":"Mechanism of vasopressin-induced platelet aggregation","volume":"45","author":"Filep","year":"1987","journal-title":"Thromb Res"},{"key":"key\n\t\t\t\t2019010709180960700_gfy017-B13","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1042\/bj1760893","article-title":"Stimulation by vasopressin, angiotensin and oxytocin of gluconeogenesis in hepatocyte suspensions","volume":"176","author":"Whitton","year":"1978","journal-title":"Biochem J"},{"key":"key\n\t\t\t\t2019010709180960700_gfy017-B14","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/0304-4165(79)90371-4","article-title":"The nature of the hepatic receptors involved in vasopressin-induced glycogenolysis","volume":"588","author":"Keppens","year":"1979","journal-title":"Biochim Biophys Acta"},{"key":"key\n\t\t\t\t2019010709180960700_gfy017-B15","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1172\/JCI200419656","article-title":"The vasopressin V1b receptor critically regulates hypothalamic-pituitary-adrenal axis activity under both stress and resting conditions","volume":"113","author":"Tanoue","year":"2004","journal-title":"J Clin Invest"},{"key":"key\n\t\t\t\t2019010709180960700_gfy017-B16","first-page":"1522","article-title":"Vasopressin stimulates cortisol secretion from human adrenocortical tissue through activation of V1 receptors","volume":"76","author":"Perraudin","year":"1993","journal-title":"J Clin Endocrinol Metab"},{"key":"key\n\t\t\t\t2019010709180960700_gfy017-B17","doi-asserted-by":"crossref","first-page":"1184","DOI":"10.1053\/meta.2002.34052","article-title":"Glucose dependency of arginine vasopressin-induced insulin and glucagon release from the perfused rat pancreas","volume":"51","author":"Abu-Basha","year":"2002","journal-title":"Metab Clin Exp"},{"key":"key\n\t\t\t\t2019010709180960700_gfy017-B18","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.1172\/JCI108377","article-title":"Distribution, blood transport, and degradation of antidiuretic hormone in man","volume":"57","author":"Baumann","year":"1976","journal-title":"J Clin Invest"},{"key":"key\n\t\t\t\t2019010709180960700_gfy017-B19","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1373\/clinchem.2005.060038","article-title":"Assay for the measurement of copeptin, a stable peptide derived from the precursor of vasopressin","volume":"52","author":"Morgenthaler","year":"2006","journal-title":"Clin Chem"},{"key":"key\n\t\t\t\t2019010709180960700_gfy017-B20","doi-asserted-by":"crossref","first-page":"2432","DOI":"10.1210\/jc.2016-1113","article-title":"Plasma copeptin, AVP gene variants, and incidence of type 2 diabetes in a cohort from the community","volume":"101","author":"Roussel","year":"2016","journal-title":"J Clin Endocrinol Metab"},{"key":"key\n\t\t\t\t2019010709180960700_gfy017-B21","doi-asserted-by":"crossref","first-page":"991","DOI":"10.1016\/S0024-3205(99)00330-6","article-title":"Contribution of vasopressin to progression of chronic renal failure: study in Brattleboro rats","volume":"65","author":"Bouby","year":"1999","journal-title":"Life Sci"},{"key":"key\n\t\t\t\t2019010709180960700_gfy017-B22","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1093\/ndt\/18.3.497","article-title":"Vasopressin increases urinary albumin excretion in rats and humans: involvement of V2 receptors and the renin-angiotensin system","volume":"18","author":"Bardoux","year":"2003","journal-title":"Nephrol Dial Transplant"},{"key":"key\n\t\t\t\t2019010709180960700_gfy017-B23","first-page":"F973","article-title":"Effect of water intake on the progression of chronic renal failure in the 5\/6 nephrectomized rat","volume":"258","author":"Bouby","year":"1990","journal-title":"Am J Physiol"},{"key":"key\n\t\t\t\t2019010709180960700_gfy017-B24","doi-asserted-by":"crossref","first-page":"960","DOI":"10.1038\/ki.2009.267","article-title":"V1\/V2 Vasopressin receptor antagonism potentiates the renoprotection of renin-angiotensin system inhibition in rats with renal mass reduction","volume":"76","author":"Perico","year":"2009","journal-title":"Kidney Int"},{"key":"key\n\t\t\t\t2019010709180960700_gfy017-B25","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1111\/j.1440-1797.2010.01415.x","article-title":"Fluid and nutrient intake and risk of chronic kidney disease","volume":"16","author":"Strippoli","year":"2011","journal-title":"Nephrology (Carlton)"},{"key":"key\n\t\t\t\t2019010709180960700_gfy017-B26","doi-asserted-by":"crossref","first-page":"2634","DOI":"10.2215\/CJN.01990211","article-title":"Urine volume and change in estimated GFR in a community-based cohort study","volume":"6","author":"Clark","year":"2011","journal-title":"Clin J Am Soc Nephrol"},{"key":"key\n\t\t\t\t2019010709180960700_gfy017-B27","doi-asserted-by":"crossref","first-page":"1062","DOI":"10.1016\/j.jdiacomp.2015.07.006","article-title":"Association between copeptin and declining glomerular filtration rate in people with newly diagnosed diabetes. The Skaraborg Diabetes Register","volume":"29","author":"Pikkemaat","year":"2015","journal-title":"J Diabetes Complications"},{"key":"key\n\t\t\t\t2019010709180960700_gfy017-B28","doi-asserted-by":"crossref","first-page":"1680","DOI":"10.1007\/s00125-013-2922-0","article-title":"Copeptin, a surrogate marker for arginine vasopressin, is associated with declining glomerular filtration in patients with diabetes mellitus (ZODIAC-33)","volume":"56","author":"Boertien","year":"2013","journal-title":"Diabetologia"},{"key":"key\n\t\t\t\t2019010709180960700_gfy017-B29","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1159\/000439061","article-title":"Plasma copeptin and decline in renal function in a cohort from the community: the prospective D.E.S.I.R. study","volume":"42","author":"Roussel","year":"2015","journal-title":"Am J Nephrol"},{"key":"key\n\t\t\t\t2019010709180960700_gfy017-B30","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1159\/000447522","article-title":"Increased levels of copeptin, a surrogate marker of arginine vasopressin, are associated with an increased risk of chronic kidney disease in a general population","volume":"44","author":"Tasevska","year":"2016","journal-title":"Am J Nephrol"},{"key":"key\n\t\t\t\t2019010709180960700_gfy017-B31","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1111\/j.1365-2796.1993.tb00647.x","article-title":"The malmo diet and cancer study. Design and feasibility","volume":"233","author":"Berglund","year":"1993","journal-title":"J Intern Med"},{"key":"key\n\t\t\t\t2019010709180960700_gfy017-B32","doi-asserted-by":"crossref","first-page":"1411","DOI":"10.1161\/ATVBAHA.107.142679","article-title":"Elevated Lp-PLA2 levels add prognostic information to the metabolic syndrome on incidence of cardiovascular events among middle-aged nondiabetic subjects","volume":"27","author":"Persson","year":"2007","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"key\n\t\t\t\t2019010709180960700_gfy017-B33","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1186\/1471-2458-11-450","article-title":"External review and validation of the Swedish national inpatient register","volume":"11","author":"Ludvigsson","year":"2011","journal-title":"BMC Public Health"},{"key":"key\n\t\t\t\t2019010709180960700_gfy017-B34","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1093\/ije\/29.3.495","article-title":"Comparing Swedish hospital discharge records with death certificates: implications for mortality statistics","volume":"29","author":"Johansson","year":"2000","journal-title":"Int J Epidemiol"},{"key":"key\n\t\t\t\t2019010709180960700_gfy017-B35","year":"2008"},{"key":"key\n\t\t\t\t2019010709180960700_gfy017-B36","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1056\/NEJMoa1114248","article-title":"Estimating glomerular filtration rate from serum creatinine and cystatin C","volume":"367","author":"Inker","year":"2012","journal-title":"N Engl J Med"},{"key":"key\n\t\t\t\t2019010709180960700_gfy017-B37","doi-asserted-by":"crossref","first-page":"1327","DOI":"10.1016\/j.bbadis.2011.06.012","article-title":"Fibrosis and progression of autosomal dominant polycystic kidney disease (ADPKD)","volume":"1812","author":"Norman","year":"2011","journal-title":"Biochim Biophys Acta"},{"key":"key\n\t\t\t\t2019010709180960700_gfy017-B38","first-page":"41","article-title":"Obstructive renal injury: from fluid mechanics to molecular cell biology","volume":"2","author":"Ucero","year":"2010","journal-title":"Open Access J Urol"},{"key":"key\n\t\t\t\t2019010709180960700_gfy017-B39","doi-asserted-by":"crossref","first-page":"10397","DOI":"10.1073\/pnas.96.18.10397","article-title":"Vasopressin contributes to hyperfiltration, albuminuria, and renal hypertrophy in diabetes mellitus: study in vasopressin-deficient Brattleboro rats","volume":"96","author":"Bardoux","year":"1999","journal-title":"Proc Natl Acad Sci USA"},{"key":"key\n\t\t\t\t2019010709180960700_gfy017-B40","doi-asserted-by":"crossref","first-page":"2934","DOI":"10.1097\/01.ASN.0000095249.99803.85","article-title":"Risk factors for chronic kidney disease: a prospective study of 23, 534 men and women in Washington County, Maryland","volume":"14","author":"Haroun","year":"2003","journal-title":"J Am Soc Nephrol"},{"key":"key\n\t\t\t\t2019010709180960700_gfy017-B41","doi-asserted-by":"crossref","first-page":"1293","DOI":"10.1001\/jama.1997.03540400043029","article-title":"End-stage renal disease in African-American and white men. 16-year MRFIT findings","volume":"277","author":"Klag","year":"1997","journal-title":"JAMA"},{"key":"key\n\t\t\t\t2019010709180960700_gfy017-B42","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1016\/S0008-6363(01)00328-5","article-title":"Antidiuretic action of vasopressin: quantitative aspects and interaction between V1a and V2 receptor-mediated effects","volume":"51","author":"Bankir","year":"2001","journal-title":"Cardiovasc Res"},{"key":"key\n\t\t\t\t2019010709180960700_gfy017-B43","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1146\/annurev.ph.56.030194.003431","article-title":"Hormonal signaling and regulation of salt and water transport in the collecting duct","volume":"56","author":"Breyer","year":"1994","journal-title":"Annu Rev Physiol"},{"key":"key\n\t\t\t\t2019010709180960700_gfy017-B44","doi-asserted-by":"crossref","first-page":"842","DOI":"10.1681\/ASN.V76842","article-title":"Vasopressin increases glomerular filtration rate in conscious rats through its antidiuretic action","volume":"7","author":"Bouby","year":"1996","journal-title":"J Am Soc Nephrol"},{"key":"key\n\t\t\t\t2019010709180960700_gfy017-B45","doi-asserted-by":"crossref","first-page":"1598","DOI":"10.1038\/ki.1996.232","article-title":"Direct and indirect cost of urea excretion","volume":"49","author":"Bankir","year":"1996","journal-title":"Kidney Int"},{"key":"key\n\t\t\t\t2019010709180960700_gfy017-B46","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1038\/ki.1983.72","article-title":"Hemodynamically mediated glomerular injury and the progressive nature of kidney disease","volume":"23","author":"Brenner","year":"1983","journal-title":"Kidney Int"},{"key":"key\n\t\t\t\t2019010709180960700_gfy017-B47","doi-asserted-by":"crossref","first-page":"1140","DOI":"10.2215\/CJN.00790209","article-title":"A case for water in the treatment of polycystic kidney disease","volume":"4","author":"Torres","year":"2009","journal-title":"Clin J Am Soc Nephrol"},{"key":"key\n\t\t\t\t2019010709180960700_gfy017-B48","doi-asserted-by":"crossref","first-page":"3220","DOI":"10.1210\/endo.139.7.6121","article-title":"Glucocorticoids increase vasopressin V1b receptor coupling to phospholipase C","volume":"139","author":"Rabadan-Diehl","year":"1998","journal-title":"Endocrinology"},{"key":"key\n\t\t\t\t2019010709180960700_gfy017-B49","doi-asserted-by":"crossref","first-page":"2692","DOI":"10.1210\/jc.2009-0370","article-title":"Clinical review: the pathogenetic role of cortisol in the metabolic syndrome: a hypothesis","volume":"94","author":"Anagnostis","year":"2009","journal-title":"J Clin Endocrinol Metab"},{"key":"key\n\t\t\t\t2019010709180960700_gfy017-B50","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.ygcen.2010.07.004","article-title":"Cushing\u2019s syndrome, glucocorticoids and the kidney","volume":"169","author":"Smets","year":"2010","journal-title":"Gen Comp Endocrinol"}],"container-title":["Nephrology Dialysis Transplantation"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/ndt\/article-pdf\/34\/1\/74\/27376152\/gfy017.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,29]],"date-time":"2025-06-29T21:00:21Z","timestamp":1751230821000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ndt\/article\/34\/1\/74\/4868486"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,2,16]]},"references-count":50,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2018,2,16]]},"published-print":{"date-parts":[[2019,1,1]]}},"URL":"https:\/\/doi.org\/10.1093\/ndt\/gfy017","relation":{},"ISSN":["0931-0509","1460-2385"],"issn-type":[{"value":"0931-0509","type":"print"},{"value":"1460-2385","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2019,1]]},"published":{"date-parts":[[2018,2,16]]}}}