{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T06:57:00Z","timestamp":1790146620013,"version":"4.0.1"},"reference-count":42,"publisher":"Oxford University Press (OUP)","issue":"7","license":[{"start":{"date-parts":[[2020,2,6]],"date-time":"2020-02-06T00:00:00Z","timestamp":1580947200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,7,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>We quantified the spontaneous imaging growth rate of oligodendrogliomas. We assessed whether (i) it discriminates between World Health Organization (WHO) grade II and grade III oligodendrogliomas, and (ii) grade III oligodendrogliomas with neo-angiogenesis are associated with more fast growth rates (\u22658 mm\/y).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This work employed a retrospective bicentric cohort study (2010\u20132016) of adult patients harboring a newly diagnosed supratentorial oligodendroglioma, isocitrate dehydrogenase (IDH) mutant and 1p\/19q codeleted (WHO 2016 classification), with a minimum of 2 available MRIs before any treatment (minimum 6-week interval) to measure the spontaneous tumor growth rate.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>We included 108 patients (age 44.7 \u00b1 14.1 y, 60 males). The tumor growth rate was higher in grade III oligodendrogliomas with neo-angiogenesis (n = 37, median 10.4 mm\/y, mean 10.0 \u00b1 6.9) than in grade III oligodendrogliomas with increased mitosis count only (cutoff \u22656 mitoses, n = 18, median 3.9 mm\/y, mean 4.5 \u00b1 3.2; P = 0.004), and higher than in grade II oligodendrogliomas (n = 53, median 2.3 mm\/y, mean 2.8 \u00b1 2.2; P &amp;lt; 0.001). There was increased prevalence of fast tumor growth rates in grade III oligodendrogliomas with neo-angiogenesis (54.1%) compared with grade III oligodendrogliomas with increased mitosis count only (11.1%; P &amp;lt; 0.001), and in grade II oligodendrogliomas (0.0%; P &amp;lt; 0.001). The tumor growth rate trends did not differ between centers (P = 0.121). Neo-angiogenesis (P &amp;lt; 0.001) and mitosis count at \u22659 (P = 0.013) were independently associated with tumor growth rates \u22658 mm\/year. A tumor growth rate \u22658 mm\/year was the only predictor independently associated with shorter progression-free survival (P = 0.041).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The spontaneous tumor growth rate recapitulates oligodendroglioma aggressiveness, permits identification of grade III oligodendrogliomas preoperatively when \u22658 mm\/year, and questions the grading by mitosis count.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/neuonc\/noaa022","type":"journal-article","created":{"date-parts":[[2020,2,4]],"date-time":"2020-02-04T23:31:51Z","timestamp":1580859111000},"page":"993-1005","source":"Crossref","is-referenced-by-count":21,"title":["Imaging growth as a predictor of grade of malignancy and aggressiveness of IDH-mutant and 1p\/19q-codeleted oligodendrogliomas in adults"],"prefix":"10.1093","volume":"22","author":[{"given":"Alexandre","family":"Roux","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, University Hospital Group for Psychiatry and Neurosciences (GHU)\u2013Sainte-Anne Hospital, Paris, France"},{"name":"Paris Descartes University, Sorbonne Paris Cit\u00e9, Paris, France"},{"name":"INSERM Unit 1266, Imaging Biomarkers of Brain Disorders (IMA-BRAIN), Institute of Psychiatry and Neurosciences of Paris, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arnault","family":"Tauziede-Espariat","sequence":"first","affiliation":[{"name":"Paris Descartes University, Sorbonne Paris Cit\u00e9, Paris, France"},{"name":"INSERM Unit 1266, Imaging Biomarkers of Brain Disorders (IMA-BRAIN), Institute of Psychiatry and Neurosciences of Paris, Paris, France"},{"name":"Department of Neuropathology, GHU\u2013Sainte-Anne Hospital, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc","family":"Zanello","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, University Hospital Group for Psychiatry and Neurosciences (GHU)\u2013Sainte-Anne Hospital, Paris, France"},{"name":"Paris Descartes University, Sorbonne Paris Cit\u00e9, Paris, France"},{"name":"INSERM Unit 1266, Imaging Biomarkers of Brain Disorders (IMA-BRAIN), Institute of Psychiatry and Neurosciences of Paris, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sophie","family":"Peeters","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, University of California Los Angeles, Los Angeles, California, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gilles","family":"Zah-Bi","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, University Hospital Group for Psychiatry and Neurosciences (GHU)\u2013Sainte-Anne Hospital, Paris, France"},{"name":"Paris Descartes University, Sorbonne Paris Cit\u00e9, Paris, France"},{"name":"INSERM Unit 1266, Imaging Biomarkers of Brain Disorders (IMA-BRAIN), Institute of Psychiatry and Neurosciences of Paris, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eduardo","family":"Parraga","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, University Hospital Group for Psychiatry and Neurosciences (GHU)\u2013Sainte-Anne Hospital, Paris, France"},{"name":"Paris Descartes University, Sorbonne Paris Cit\u00e9, Paris, France"},{"name":"INSERM Unit 1266, Imaging Biomarkers of Brain Disorders (IMA-BRAIN), Institute of Psychiatry and Neurosciences of Paris, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Myriam","family":"Edjlali","sequence":"first","affiliation":[{"name":"Paris Descartes University, Sorbonne Paris Cit\u00e9, Paris, France"},{"name":"INSERM Unit 1266, Imaging Biomarkers of Brain Disorders (IMA-BRAIN), Institute of Psychiatry and Neurosciences of Paris, Paris, France"},{"name":"Department of Neuroradiology, GHU\u2013Sainte-Anne Hospital, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emmanu\u00e8le","family":"Lechapt","sequence":"first","affiliation":[{"name":"Paris Descartes University, Sorbonne Paris Cit\u00e9, Paris, France"},{"name":"INSERM Unit 1266, Imaging Biomarkers of Brain Disorders (IMA-BRAIN), Institute of Psychiatry and Neurosciences of Paris, Paris, France"},{"name":"Department of Neuropathology, GHU\u2013Sainte-Anne Hospital, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natalia","family":"Shor","sequence":"first","affiliation":[{"name":"Department of Neuroradiology, Piti\u00e9-Salp\u00eatri\u00e8re Hospital, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luisa","family":"Bellu","sequence":"first","affiliation":[{"name":"Department of Neuro-Oncology, Piti\u00e9-Salp\u00eatri\u00e8re Hospital, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giulia","family":"Berzero","sequence":"first","affiliation":[{"name":"Department of Neuro-Oncology, Piti\u00e9-Salp\u00eatri\u00e8re Hospital, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Didier","family":"Dormont","sequence":"first","affiliation":[{"name":"Department of Neuroradiology, Piti\u00e9-Salp\u00eatri\u00e8re Hospital, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edouard","family":"Dezamis","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, University Hospital Group for Psychiatry and Neurosciences (GHU)\u2013Sainte-Anne Hospital, Paris, France"},{"name":"Paris Descartes University, Sorbonne Paris Cit\u00e9, Paris, France"},{"name":"INSERM Unit 1266, Imaging Biomarkers of Brain Disorders (IMA-BRAIN), Institute of Psychiatry and Neurosciences of Paris, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabrice","family":"Chretien","sequence":"first","affiliation":[{"name":"Paris Descartes University, Sorbonne Paris Cit\u00e9, Paris, France"},{"name":"INSERM Unit 1266, Imaging Biomarkers of Brain Disorders (IMA-BRAIN), Institute of Psychiatry and Neurosciences of Paris, Paris, France"},{"name":"Department of Neuropathology, GHU\u2013Sainte-Anne Hospital, Paris, France"},{"name":"Laboratory of Experimental Neuropathology, Pasteur Institute, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine","family":"Oppenheim","sequence":"first","affiliation":[{"name":"Paris Descartes University, Sorbonne Paris Cit\u00e9, Paris, France"},{"name":"INSERM Unit 1266, Imaging Biomarkers of Brain Disorders (IMA-BRAIN), Institute of Psychiatry and Neurosciences of Paris, Paris, France"},{"name":"Department of Neuroradiology, GHU\u2013Sainte-Anne Hospital, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc","family":"Sanson","sequence":"first","affiliation":[{"name":"Department of Neuro-Oncology, Piti\u00e9-Salp\u00eatri\u00e8re Hospital, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pascale","family":"Varlet","sequence":"first","affiliation":[{"name":"Paris Descartes University, Sorbonne Paris Cit\u00e9, Paris, France"},{"name":"INSERM Unit 1266, Imaging Biomarkers of Brain Disorders (IMA-BRAIN), Institute of Psychiatry and Neurosciences of Paris, Paris, France"},{"name":"Department of Neuropathology, GHU\u2013Sainte-Anne Hospital, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laurent","family":"Capelle","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, Piti\u00e9-Salp\u00eatri\u00e8re Hospital, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fr\u00e9d\u00e9ric","family":"Dhermain","sequence":"first","affiliation":[{"name":"Department of Radiotherapy, Gustave Roussy University Hospital, Villejuif, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1652-9844","authenticated-orcid":false,"given":"Johan","family":"Pallud","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, University Hospital Group for Psychiatry and Neurosciences (GHU)\u2013Sainte-Anne Hospital, Paris, France"},{"name":"Paris Descartes University, Sorbonne Paris Cit\u00e9, Paris, France"},{"name":"INSERM Unit 1266, Imaging Biomarkers of Brain Disorders (IMA-BRAIN), Institute of Psychiatry and Neurosciences of Paris, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2020,2,6]]},"reference":[{"key":"2020070708541420100_CIT0001","volume-title":"WHO Classification of Tumours of the Central Nervous System.","author":"Louis","edition":"Revised 4th edn"},{"issue":"5","key":"2020070708541420100_CIT0002","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1093\/neuonc\/nos331","article-title":"Velocity of tumor spontaneous expansion predicts long-term outcomes for diffuse low-grade gliomas","volume":"15","author":"Pallud","year":"2013","journal-title":"Neuro Oncol."},{"issue":"21","key":"2020070708541420100_CIT0003","doi-asserted-by":"crossref","first-page":"2394","DOI":"10.1200\/JCO.2017.72.6737","article-title":"Diffuse infiltrating oligodendroglioma and astrocytoma","volume":"35","author":"van den Bent","year":"2017","journal-title":"J Clin Oncol."},{"issue":"3","key":"2020070708541420100_CIT0004","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1093\/jnen\/60.3.248","article-title":"Oligodendrogliomas: reproducibility and prognostic value of histologic diagnosis and grading","volume":"60","author":"Giannini","year":"2001","journal-title":"J Neuropathol Exp Neurol."},{"issue":"3","key":"2020070708541420100_CIT0005","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1200\/JCO.2012.43.2229","article-title":"Adjuvant procarbazine, lomustine, and vincristine chemotherapy in newly diagnosed anaplastic oligodendroglioma: long-term follow-up of EORTC brain tumor group study 26951","volume":"31","author":"van den Bent","year":"2013","journal-title":"J Clin Oncol."},{"issue":"3","key":"2020070708541420100_CIT0006","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1200\/JCO.2012.43.2674","article-title":"Phase III trial of chemoradiotherapy for anaplastic oligodendroglioma: long-term results of RTOG 9402","volume":"31","author":"Cairncross","year":"2013","journal-title":"J Clin Oncol."},{"issue":"6","key":"2020070708541420100_CIT0007","doi-asserted-by":"crossref","first-page":"e315","DOI":"10.1016\/S1470-2045(17)30194-8","article-title":"European Association for Neuro-Oncology (EANO) guideline on the diagnosis and treatment of adult astrocytic and oligodendroglial gliomas","volume":"18","author":"Weller","year":"2017","journal-title":"Lancet Oncol."},{"key":"2020070708541420100_CIT0008","doi-asserted-by":"crossref","DOI":"10.1093\/neuonc\/noz033","article-title":"Recent developments and future directions in adult lower-grade gliomas: Society for Neuro-Oncology (SNO) and European Association of Neuro-Oncology (EANO) consensus","author":"Schiff","year":"2019","journal-title":"Neuro Oncol."},{"key":"2020070708541420100_CIT0009","doi-asserted-by":"crossref","first-page":"e346","DOI":"10.1016\/j.wneu.2017.10.172","article-title":"Low-grade glioma with foci of early transformation does not necessarily require adjuvant therapy after radical surgical resection","volume":"110","author":"Al-Tamimi","year":"2018","journal-title":"World Neurosurg."},{"key":"2020070708541420100_CIT0010","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1016\/j.wneu.2017.12.073","article-title":"Actual oncologic impact of radical surgical resection for malignant gliomas","volume":"112","author":"Pallud","year":"2018","journal-title":"World Neurosurg."},{"key":"2020070708541420100_CIT0011","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3171\/2019.4.JNS183395","article-title":"To treat or not to treat? A retrospective multicenter assessment of survival in patients with IDH-mutant low-grade glioma based on adjuvant treatment","author":"Pa\u013ea","year":"2019","journal-title":"J Neurosurg."},{"issue":"1","key":"2020070708541420100_CIT0012","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1007\/s00401-014-1370-3","article-title":"ATRX and IDH1-R132H immunohistochemistry with subsequent copy number analysis and IDH sequencing as a basis for an \u201cintegrated\u201d diagnostic approach for adult astrocytoma, oligodendroglioma and glioblastoma","volume":"129","author":"Reuss","year":"2015","journal-title":"Acta Neuropathol (Berl)."},{"issue":"5","key":"2020070708541420100_CIT0013","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1038\/ng.3273","article-title":"Mutational landscape and clonal architecture in grade II and III gliomas","volume":"47","author":"Suzuki","year":"2015","journal-title":"Nat Genet."},{"issue":"4","key":"2020070708541420100_CIT0014","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1007\/s00401-015-1398-z","article-title":"IDH mutation status and role of WHO grade and mitotic index in overall survival in grade II-III diffuse gliomas","volume":"129","author":"Olar","year":"2015","journal-title":"Acta Neuropathol."},{"issue":"6","key":"2020070708541420100_CIT0015","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1007\/s00401-017-1690-1","article-title":"Adult infiltrating gliomas with WHO 2016 integrated diagnosis: additional prognostic roles of ATRX and TERT","volume":"133","author":"Pekmezci","year":"2017","journal-title":"Acta Neuropathol (Berl)."},{"issue":"26","key":"2020070708541420100_CIT0016","doi-asserted-by":"crossref","first-page":"2481","DOI":"10.1056\/NEJMoa1402121","article-title":"Comprehensive, integrative genomic analysis of diffuse lower-grade gliomas","volume":"372","author":"Cancer Genome Atlas Research Network","year":"2015","journal-title":"N Engl J Med"},{"key":"2020070708541420100_CIT0017","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1159\/000467376","article-title":"Chemotherapy of oligodendrogliomas","volume":"31","author":"Drappatz","year":"2018","journal-title":"Prog Neurol Surg."},{"issue":"12","key":"2020070708541420100_CIT0018","first-page":"1519","article-title":"CDKN2A homozygous deletion is a strong adverse prognosis factor in diffuse malignant IDH-mutant gliomas","volume":"21","author":"Appay","year":"2019","journal-title":"Neuro Oncol."},{"issue":"1","key":"2020070708541420100_CIT0019","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1186\/s40478-017-0443-7","article-title":"Multidimensional scaling of diffuse gliomas: application to the 2016 World Health Organization classification system with prognostically relevant molecular subtype discovery","volume":"5","author":"Cimino","year":"2017","journal-title":"Acta Neuropathol Commun."},{"issue":"3","key":"2020070708541420100_CIT0020","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1093\/neuonc\/nov182","article-title":"Molecular classification of anaplastic oligodendroglioma using next-generation sequencing: a report of the prospective randomized EORTC Brain Tumor Group 26951 phase III trial","volume":"18","author":"Dubbink","year":"2016","journal-title":"Neuro Oncol."},{"issue":"3","key":"2020070708541420100_CIT0021","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1227\/NEU.0b013e31826213de","article-title":"Quantitative morphological magnetic resonance imaging follow-up of low-grade glioma: a plea for systematic measurement of growth rates","volume":"71","author":"Pallud","year":"2012","journal-title":"Neurosurgery."},{"issue":"3","key":"2020070708541420100_CIT0022","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1007\/s10143-008-0128-6","article-title":"Computational modeling of the WHO grade II glioma dynamics: principles and applications to management paradigm","volume":"31","author":"Mandonnet","year":"2008","journal-title":"Neurosurg Rev."},{"issue":"3","key":"2020070708541420100_CIT0023","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1002\/ana.20946","article-title":"Prognostic value of initial magnetic resonance imaging growth rates for World Health Organization grade II gliomas","volume":"60","author":"Pallud","year":"2006","journal-title":"Ann Neurol."},{"issue":"8","key":"2020070708541420100_CIT0024","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1038\/nrclinonc.2009.92","article-title":"Quantitative imaging biomarkers in neuro-oncology","volume":"6","author":"Waldman","year":"2009","journal-title":"Nat Rev Clin Oncol."},{"issue":"2","key":"2020070708541420100_CIT0025","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1148\/radiol.2532081623","article-title":"Low-grade gliomas: six-month tumor growth predicts patient outcome better than admission tumor volume, relative cerebral blood volume, and apparent diffusion coefficient","volume":"253","author":"Brasil Caseiras","year":"2009","journal-title":"Radiology"},{"issue":"1","key":"2020070708541420100_CIT0026","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/j.media.2011.05.014","article-title":"Differential MRI analysis for quantification of low grade glioma growth","volume":"16","author":"Angelini","year":"2012","journal-title":"Med Image Anal."},{"issue":"3","key":"2020070708541420100_CIT0027","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1007\/s11060-015-1908-9","article-title":"The role of imaging in the management of adults with diffuse low grade glioma: a systematic review and evidence-based clinical practice guideline","volume":"125","author":"Fouke","year":"2015","journal-title":"J Neurooncol."},{"issue":"1","key":"2020070708541420100_CIT0028","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1007\/s11060-018-2857-x","article-title":"Tumor growth dynamics in serially-imaged low-grade glioma patients","volume":"139","author":"Gui","year":"2018","journal-title":"J Neurooncol."},{"issue":"1","key":"2020070708541420100_CIT0029","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.nec.2018.08.002","article-title":"Clinical presentation, natural history, and prognosis of diffuse low-grade gliomas","volume":"30","author":"Smits","year":"2019","journal-title":"Neurosurg Clin N Am."},{"issue":"5","key":"2020070708541420100_CIT0030","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1002\/ana.21125","article-title":"Dynamic history of low-grade gliomas before and after temozolomide treatment","volume":"61","author":"Ricard","year":"2007","journal-title":"Ann Neurol."},{"issue":"3","key":"2020070708541420100_CIT0031","doi-asserted-by":"crossref","first-page":"1014","DOI":"10.1148\/radiol.100299","article-title":"Comment on parameters of low-grade glioma as predictors","volume":"256","author":"Pallud","year":"2010","journal-title":"Radiology."},{"issue":"8","key":"2020070708541420100_CIT0032","doi-asserted-by":"crossref","first-page":"2076","DOI":"10.1200\/JCO.2002.08.121","article-title":"Prognostic factors for survival in adult patients with cerebral low-grade glioma","volume":"20","author":"Pignatti","year":"2002","journal-title":"J Clin Oncol."},{"issue":"2","key":"2020070708541420100_CIT0033","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1215\/15228517-2008-066","article-title":"Prognostic significance of imaging contrast enhancement for WHO grade II gliomas","volume":"11","author":"Pallud","year":"2009","journal-title":"Neuro Oncol."},{"key":"2020070708541420100_CIT0034","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.ejca.2018.10.019","article-title":"Contrast enhancement is a prognostic factor in IDH1\/2 mutant, but not in wild-type WHO grade II\/III glioma as confirmed by machine learning","volume":"107","author":"Suchorska","year":"2019","journal-title":"Eur J Cancer."},{"issue":"4","key":"2020070708541420100_CIT0035","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1111\/bpa.12732","article-title":"cIMPACT-NOW: a practical summary of diagnostic points from round 1 updates","volume":"29","author":"Louis","year":"2019","journal-title":"Brain Pathol."},{"issue":"4","key":"2020070708541420100_CIT0036","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1002\/ana.10528","article-title":"Continuous growth of mean tumor diameter in a subset of grade II gliomas","volume":"53","author":"Mandonnet","year":"2003","journal-title":"Ann Neurol."},{"issue":"1","key":"2020070708541420100_CIT0037","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1007\/s10143-009-0229-x","article-title":"Inter- and intrapatients comparison of WHO grade II glioma kinetics before and after surgical resection","volume":"33","author":"Mandonnet","year":"2010","journal-title":"Neurosurg Rev."},{"issue":"10","key":"2020070708541420100_CIT0038","doi-asserted-by":"crossref","first-page":"1078","DOI":"10.1093\/neuonc\/noq055","article-title":"Prolonged response without prolonged chemotherapy: a lesson from PCV chemotherapy in low-grade gliomas","volume":"12","author":"Peyre","year":"2010","journal-title":"Neuro Oncol."},{"issue":"1","key":"2020070708541420100_CIT0039","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1007\/s11060-009-9991-4","article-title":"Predictive value of multimodality MRI using conventional, perfusion, and spectroscopy MR in anaplastic transformation of low-grade oligodendrogliomas","volume":"97","author":"Hlaihel","year":"2010","journal-title":"J Neurooncol."},{"issue":"5","key":"2020070708541420100_CIT0040","doi-asserted-by":"crossref","first-page":"e1002810","DOI":"10.1371\/journal.pmed.1002810","article-title":"Diagnosing growth in low-grade gliomas with and without longitudinal volume measurements: a retrospective observational study","volume":"16","author":"Fathallah-Shaykh","year":"2019","journal-title":"PLoS Med."},{"issue":"6","key":"2020070708541420100_CIT0041","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1093\/neuonc\/nou332","article-title":"Imaging of gliomas at 1.5 and 3 Tesla\u2014a comparative study","volume":"17","author":"Tselikas","year":"2015","journal-title":"Neuro Oncol."},{"key":"2020070708541420100_CIT0042","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1038\/s41698-018-0067-9","article-title":"Multi-faceted computational assessment of risk and progression in oligodendroglioma implicates NOTCH and PI3K pathways","volume":"2","author":"Halani","year":"2018","journal-title":"NPJ Precis Oncol."}],"container-title":["Neuro-Oncology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/neuro-oncology\/advance-article-pdf\/doi\/10.1093\/neuonc\/noaa022\/32761655\/noaa022.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"http:\/\/academic.oup.com\/neuro-oncology\/article-pdf\/22\/7\/993\/33471076\/noaa022.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/academic.oup.com\/neuro-oncology\/article-pdf\/22\/7\/993\/33471076\/noaa022.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,26]],"date-time":"2023-09-26T03:28:54Z","timestamp":1695698934000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/neuro-oncology\/article\/22\/7\/993\/5728482"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,2,6]]},"references-count":42,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2020,2,6]]},"published-print":{"date-parts":[[2020,7,7]]}},"URL":"https:\/\/doi.org\/10.1093\/neuonc\/noaa022","relation":{},"ISSN":["1522-8517","1523-5866"],"issn-type":[{"value":"1522-8517","type":"print"},{"value":"1523-5866","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2020,7]]},"published":{"date-parts":[[2020,2,6]]}}}