{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T11:19:59Z","timestamp":1791371999760,"version":"4.3.1"},"reference-count":58,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2022,9,1]],"date-time":"2022-09-01T00:00:00Z","timestamp":1661990400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"DOI":"10.13039\/501100004853","name":"The Chinese University of Hong Kong","doi-asserted-by":"publisher","award":["SBRE-20-332"],"award-info":[{"award-number":["SBRE-20-332"]}],"id":[{"id":"10.13039\/501100004853","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,5,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>This study aimed to evaluate the global incidence, mortality, associated risk factors, and temporal trends of central nervous system (CNS) cancer by sex, age, and country.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>We extracted incidence and mortality of CNS cancer from the GLOBOCAN (2020), Cancer Incidence in Five Continents series I\u2013X, WHO mortality database, the Nordic Cancer Registries, and the Surveillance, Epidemiology, and End Results Program. We searched the Global Health data exchanges for the prevalence of its associated risk factors. We tested the trends by Average Annual Percentage Change (AAPC) from Joinpoint regression analysis with 95% confidence intervals in different age groups.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>The age-standardized rates (ASRs) of CNS cancer incidence and mortality were 3.5 and 2.8 per 100,000 globally. Southern Europe (ASR\u2005=\u20056.0) and Western Asia (ASR\u2005=\u20054.2) had the highest incidence and mortality, respectively. The incidence was associated with Human Development Index, Gross Domestics Products per capita, prevalence of traumatic brain injuries, occupational carcinogens exposure, and mobile phone use at the country level. There was an overall stable and mixed trend in the CNS cancer burden. However, increasing incidence was observed in younger male population from five countries, with Slovakia (AAPC\u2005=\u20055.40; 95% CI 1.88, 9.04; P\u2005=\u2005.007) reporting the largest increase.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>While the overall global trends of cancer have been largely stable, significant increasing trends were found in the younger male population. The presence of some higher-HDI countries with increasing mortality suggested an ample scope for further research and exploration of the reasons behind these epidemiological trends.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/neuonc\/noac213","type":"journal-article","created":{"date-parts":[[2022,8,31]],"date-time":"2022-08-31T12:24:07Z","timestamp":1661948647000},"page":"995-1005","source":"Crossref","is-referenced-by-count":37,"title":["Disease burden, risk factors, and trends of primary central nervous system (CNS) cancer: A global study of registries data"],"prefix":"10.1093","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6241-7210","authenticated-orcid":false,"given":"Junjie","family":"Huang","sequence":"first","affiliation":[{"name":"The Jockey Club School of Public Health and Primary Care, Faculty of Medicine, Chinese University of Hong Kong , Hong Kong SAR , China"},{"name":"Centre for Health Education and Health Promotion, Faculty of Medicine, Chinese University of Hong Kong , Hong Kong SAR , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sze Chai","family":"Chan","sequence":"additional","affiliation":[{"name":"The Jockey Club School of Public Health and Primary Care, Faculty of Medicine, Chinese University of Hong Kong , Hong Kong SAR , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Veeleah","family":"Lok","sequence":"additional","affiliation":[{"name":"Department of Global Public Health, Karolinska Institute, Karolinska University Hospital , Stockholm , Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lin","family":"Zhang","sequence":"additional","affiliation":[{"name":"School of Population and Global Health, The University of Melbourne , Victoria , Australia"},{"name":"School of Public Health, The Chinese Academy of Medical Sciences and Peking Union Medical College , Beijing , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xu","family":"Lin","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, The First Affiliated Hospital, School of Medicine, Zhejiang University , Hangzhou, Zhejiang , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Don Eliseo","family":"Lucero-Prisno","sequence":"additional","affiliation":[{"name":"Department of Global Health and Development, London School of Hygiene and Tropical Medicine , London , UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wanghong","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, School of Public Health, Fudan University , Shanghai , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhi-Jie","family":"Zheng","sequence":"additional","affiliation":[{"name":"Department of Global Health, School of Public Health, Peking University , Beijing , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edmar","family":"Elcarte","sequence":"additional","affiliation":[{"name":"University of the Philippines , Manila , Philippines"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mellissa","family":"Withers","sequence":"additional","affiliation":[{"name":"Department of Population and Health Sciences, Institute for Global Health, University of Southern California , Los Angeles , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin C S","family":"Wong","sequence":"additional","affiliation":[{"name":"The Jockey Club School of Public Health and Primary Care, Faculty of Medicine, Chinese University of Hong Kong , Hong Kong SAR , China"},{"name":"Centre for Health Education and Health Promotion, Faculty of Medicine, Chinese University of Hong Kong , Hong Kong SAR , China"},{"name":"School of Public Health, The Chinese Academy of Medical Sciences and Peking Union Medical College , Beijing , China"},{"name":"Department of Global Health, School of Public Health, Peking University , Beijing , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"NCD Global Health Research Group","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Association of Pacific Rim Universities (APRU)","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2022,9,1]]},"reference":[{"issue":"3","key":"2023050411183553900_CIT0001","doi-asserted-by":"crossref","first-page":"209","DOI":"10.3322\/caac.21660","article-title":"Global Cancer Statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries","volume":"71","author":"Sung","year":"2021","journal-title":"CA Cancer J Clin."},{"issue":"13","key":"2023050411183553900_CIT0002","doi-asserted-by":"crossref","first-page":"2309","DOI":"10.1016\/j.ejca.2014.05.019","article-title":"Changing incidence and improved survival of gliomas","volume":"50","author":"Ho","year":"2014","journal-title":"Eur J Cancer."},{"issue":"10125","key":"2023050411183553900_CIT0003","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1016\/S0140-6736(17)33326-3","article-title":"Global surveillance of trends in cancer survival 2000\u201314 (CONCORD-3): analysis of individual records for 37 513 025 patients diagnosed with one of 18 cancers from 322 population-based registries in 71 countries","volume":"391","author":"Allemani","year":"2018","journal-title":"Lancet."},{"issue":"3","key":"2023050411183553900_CIT0004","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1002\/(SICI)1097-0215(19960729)67:3<318::AID-IJC2>3.0.CO;2-U","article-title":"Incidence of intracranial meningiomas in Nagasaki atomic-bomb survivors","volume":"67","author":"Sadamori","year":"1996","journal-title":"Int J Cancer."},{"issue":"20","key":"2023050411183553900_CIT0005","doi-asserted-by":"crossref","first-page":"1555","DOI":"10.1093\/jnci\/94.20.1555","article-title":"Tumors of the nervous system and pituitary gland associated with atomic bomb radiation exposure","volume":"94","author":"Preston","year":"2002","journal-title":"J Natl Cancer Inst."},{"issue":"8","key":"2023050411183553900_CIT0006","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1093\/aje\/153.8.749","article-title":"Cancer incidence after childhood nasopharyngeal radium irradiation: a follow-up study in Washington County, Maryland","volume":"153","author":"Yeh","year":"2001","journal-title":"Am J Epidemiol."},{"issue":"4","key":"2023050411183553900_CIT0007","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1615\/CritRevOncog.2019032655","article-title":"Role of Epstein-Barr Virus in Glioblastoma","volume":"24","author":"Zavala-Vega","year":"2019","journal-title":"Crit Rev Oncog."},{"issue":"4","key":"2023050411183553900_CIT0008","first-page":"601","article-title":"An exploratory case-control study of brain tumors in adults","volume":"78","author":"Burch","year":"1987","journal-title":"J Natl Cancer Inst."},{"issue":"12","key":"2023050411183553900_CIT0009","doi-asserted-by":"crossref","first-page":"2514","DOI":"10.1158\/1055-9965.EPI-06-0482","article-title":"Lead, genetic susceptibility, and risk of adult brain tumors","volume":"15","author":"Rajaraman","year":"2006","journal-title":"Cancer Epidemiol Biomark Prev."},{"issue":"7","key":"2023050411183553900_CIT0010","doi-asserted-by":"crossref","first-page":"1825","DOI":"10.1038\/bjc.2014.97","article-title":"Immune-related conditions and subsequent risk of brain cancer in a cohort of 4.5 million male US veterans","volume":"110","author":"Cahoon","year":"2014","journal-title":"Br J Cancer."},{"issue":"5","key":"2023050411183553900_CIT0011","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1007\/s10072-017-2850-8","article-title":"Mobile phone use and risk of brain tumours: a systematic review of association between study quality, source of funding, and research outcomes","volume":"38","author":"Prasad","year":"2017","journal-title":"Neurol Sci."},{"issue":"16","key":"2023050411183553900_CIT0012","doi-asserted-by":"crossref","first-page":"1382","DOI":"10.1093\/jnci\/91.16.1382","article-title":"Brain and other central nervous system cancers: recent trends in incidence and mortality","volume":"91","author":"Legler","year":"1999","journal-title":"J Natl Cancer Inst."},{"issue":"5","key":"2023050411183553900_CIT0013","doi-asserted-by":"crossref","first-page":"381","DOI":"10.3322\/caac.21693","article-title":"Brain and other central nervous system tumor statistics, 2021","volume":"71","author":"Miller","year":"2021","journal-title":"CA Cancer J Clin."},{"issue":"2","key":"2023050411183553900_CIT0014","first-page":"270","article-title":"Cancers of the brain and CNS: global patterns and trends in incidence","volume":"19","author":"Miranda-Filho","year":"2017","journal-title":"Neuro Oncol."},{"key":"2023050411183553900_CIT0015","author":"International Agency for Research on Cancer WHO.","year":"2020"},{"key":"2023050411183553900_CIT0016","volume-title":"Human Development Report 2019","author":"UNDP.","year":"2019"},{"key":"2023050411183553900_CIT0017","author":"The World Bank."},{"key":"2023050411183553900_CIT0018","author":"The World Bank.","year":"2021."},{"key":"2023050411183553900_CIT0019","volume-title":"Statistical Update 2018","author":"UNDP.","year":"2018"},{"key":"2023050411183553900_CIT0020","author":"Institute for Health Metrics and Evaluation.","year":"2019"},{"key":"2023050411183553900_CIT0021","volume-title":"Cancer Incidence in Five Continents","author":"Bray","year":"2020"},{"key":"2023050411183553900_CIT0022","author":"World Health Organization.","year":"2019"},{"key":"2023050411183553900_CIT0023","author":"Danckert","year":"2019"},{"key":"2023050411183553900_CIT0024","author":"U.S. Department of Health and Human Services NIoH.","year":"2020"},{"key":"2023050411183553900_CIT0025","author":"World Health Organization.","year":"2019"},{"issue":"4","key":"2023050411183553900_CIT0026","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1136\/gutjnl-2015-310912","article-title":"Global patterns and trends in colorectal cancer incidence and mortality","volume":"66","author":"Arnold","year":"2017","journal-title":"Gut."},{"key":"2023050411183553900_CIT0027","volume-title":"Cancer Mortality for Selected Sites in 24 Countries (1950\u20131957)","author":"Segi","year":"1960"},{"issue":"1","key":"2023050411183553900_CIT0028","doi-asserted-by":"crossref","first-page":"1696","DOI":"10.1186\/s12889-020-09838-4","article-title":"The association between incidence and mortality of brain cancer and human development index (HDI): an ecological study","volume":"20","author":"Khazaei","year":"2020","journal-title":"BMC Public Health."},{"issue":"4","key":"2023050411183553900_CIT0029","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1016\/S1474-4422(18)30468-X","article-title":"Global, regional, and national burden of brain and other CNS cancer, 1990\u20132016: a systematic analysis for the Global Burden of Disease Study 2016","volume":"18","author":"Patel","year":"2019","journal-title":"Lancet Neurol."},{"key":"2023050411183553900_CIT0030","doi-asserted-by":"crossref","first-page":"240","DOI":"10.11604\/pamj.2018.30.240.14000","article-title":"Survey of magnetic resonance imaging availability in West Africa","volume":"30","author":"Ogbole","year":"2018","journal-title":"Pan Afr Med J."},{"key":"2023050411183553900_CIT0031","doi-asserted-by":"crossref","DOI":"10.1016\/S2352-3026(22)00165-X","article-title":"The epidemiological landscape of multiple myeloma: a global cancer registry estimate of disease burden, risk factors, and temporal trends","author":"Huang","year":"2022","journal-title":"Lancet Haematol."},{"issue":"8","key":"2023050411183553900_CIT0032","first-page":"11863","article-title":"Association between X-ray repair cross-complementing group 1 gene polymorphisms and glioma risk: a systematic review and meta-analysis based on 22 case-control studies","volume":"8","author":"Li","year":"2015","journal-title":"Int J Clin Exp Med."},{"issue":"7","key":"2023050411183553900_CIT0033","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1093\/neuonc\/nou087","article-title":"The epidemiology of glioma in adults: a \u201cstate of the science\u201d review","volume":"16","author":"Ostrom","year":"2014","journal-title":"Neuro Oncol."},{"issue":"4","key":"2023050411183553900_CIT0034","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1001\/jamaoncol.2016.5688","article-title":"Global, regional, and national cancer incidence, mortality, years of life lost, years lived with disability, and disability-adjusted life-years for 32 cancer groups, 1990 to 2015: a systematic analysis for the Global Burden of Disease Study","volume":"3","author":"Fitzmaurice","year":"2017","journal-title":"JAMA Oncol."},{"issue":"11","key":"2023050411183553900_CIT0035","doi-asserted-by":"crossref","first-page":"1553","DOI":"10.1001\/jamaoncol.2018.2706","article-title":"Global, regional, and national cancer incidence, mortality, years of life lost, years lived with disability, and disability-adjusted life-years for 29 cancer groups, 1990 to 2016: a systematic analysis for the Global Burden of Disease Study","volume":"4","author":"Fitzmaurice","year":"2018","journal-title":"JAMA Oncol."},{"issue":"6","key":"2023050411183553900_CIT0036","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1007\/s10552-010-9514-9","article-title":"Occupational exposure to terbufos and the incidence of cancer in the Agricultural Health Study","volume":"21","author":"Bonner","year":"2010","journal-title":"Cancer Causes Control."},{"issue":"3","key":"2023050411183553900_CIT0037","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1007\/s10654-011-9647-5","article-title":"Enigmatic sex disparities in cancer incidence","volume":"27","author":"Edgren","year":"2012","journal-title":"Eur J Epidemiol."},{"issue":"7","key":"2023050411183553900_CIT0038","doi-asserted-by":"crossref","first-page":"1194","DOI":"10.1001\/archneur.59.7.1194","article-title":"Nervous system disorders: a global epidemic","volume":"59","author":"Bergen","year":"2002","journal-title":"Arch Neurol."},{"key":"2023050411183553900_CIT0039","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/j.wneu.2015.12.048","article-title":"Global neurosurgery: The Unmet Need","volume":"88","author":"Park","year":"2016","journal-title":"World Neurosurg."},{"issue":"7","key":"2023050411183553900_CIT0040","doi-asserted-by":"crossref","first-page":"1328","DOI":"10.1089\/neu.2011.2235","article-title":"Association between traumatic brain injury and the subsequent risk of brain cancer","volume":"29","author":"Chen","year":"2012","journal-title":"J Neurotrauma."},{"issue":"2","key":"2023050411183553900_CIT0041","doi-asserted-by":"crossref","first-page":"169","DOI":"10.2105\/AJPH.80.2.169","article-title":"An analysis of occupational risks for brain cancer","volume":"80","author":"Brownson","year":"1990","journal-title":"Am J Public Health."},{"issue":"8","key":"2023050411183553900_CIT0042","doi-asserted-by":"crossref","first-page":"976","DOI":"10.1093\/aje\/kwm401","article-title":"Occupational exposure to pesticides and risk of adult brain tumors","volume":"167","author":"Samanic","year":"2008","journal-title":"Am J Epidemiol."},{"issue":"8","key":"2023050411183553900_CIT0043","doi-asserted-by":"crossref","first-page":"1246","DOI":"10.1038\/bjc.2017.285","article-title":"Occupational solvent exposure and risk of glioma in the INTEROCC study","volume":"117","author":"Benke","year":"2017","journal-title":"Br J Cancer."},{"issue":"1","key":"2023050411183553900_CIT0044","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1186\/s12940-017-0300-y","article-title":"Lifetime occupational exposure to metals and welding fumes, and risk of glioma: a 7-country population-based case\u2013control study","volume":"16","author":"Parent","year":"2017","journal-title":"Environ Health."},{"issue":"3","key":"2023050411183553900_CIT0045","doi-asserted-by":"crossref","first-page":"792","DOI":"10.1093\/ije\/dyt072","article-title":"Mobile phone use and risk of brain neoplasms and other cancers: prospective study","volume":"42","author":"Benson","year":"2013","journal-title":"Int J Epidemiol."},{"issue":"1","key":"2023050411183553900_CIT0046","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1186\/s41016-016-0059-y","article-title":"The relationship between mobile phone use and risk of brain tumor: a systematic review and meta-analysis of trails in the last decade","volume":"2","author":"Leng","year":"2016","journal-title":"Chin Neurosurg J."},{"issue":"5","key":"2023050411183553900_CIT0047","doi-asserted-by":"crossref","first-page":"704","DOI":"10.1093\/jnci\/djac042","article-title":"Cellular telephone use and the risk of brain tumors: update of the UK Million Women Study","volume":"114","author":"Sch\u00fcz","year":"2022","journal-title":"J Natl Cancer Inst."},{"key":"2023050411183553900_CIT0048","first-page":"djac109","article-title":"RE: cellular telephone use and the risk of brain tumors: update of the UK Million Women Study","author":"Moskowitz","year":"2022","journal-title":"J Natl Cancer Inst."},{"issue":"5","key":"2023050411183553900_CIT0049","doi-asserted-by":"crossref","first-page":"e0175136","DOI":"10.1371\/journal.pone.0175136","article-title":"Mobile phone use and glioma risk: a systematic review and meta-analysis","volume":"12","author":"Yang","year":"2017","journal-title":"PLoS One."},{"issue":"21","key":"2023050411183553900_CIT0050","doi-asserted-by":"crossref","first-page":"8079","DOI":"10.3390\/ijerph17218079","article-title":"Cellular phone use and risk of tumors: systematic review and meta-analysis","volume":"17","author":"Choi","year":"2020","journal-title":"Int J Environ Res Public Health."},{"issue":"5","key":"2023050411183553900_CIT0051","doi-asserted-by":"crossref","first-page":"673","DOI":"10.3109\/02841861003610200","article-title":"Trends in survival of patients diagnosed with cancers of the brain and nervous system, thyroid, eye, bone, and soft tissues in the Nordic countries 1964\u20132003 followed up until the end of 2006","volume":"49","author":"Bray","year":"2010","journal-title":"Acta Oncol."},{"issue":"3","key":"2023050411183553900_CIT0052","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1158\/1055-9965.EPI-07-0725","article-title":"Issues of diagnostic review in brain tumor studies: from the Brain Tumor Epidemiology Consortium","volume":"17","author":"Davis","year":"2008","journal-title":"Cancer Epidemiol Biomark Prev."},{"issue":"Suppl 2","key":"2023050411183553900_CIT0053","doi-asserted-by":"crossref","first-page":"ii1","DOI":"10.1093\/neuonc\/not151","article-title":"CBTRUS statistical report: primary brain and central nervous system tumors diagnosed in the United States in 2006\u20132010","volume":"15","author":"Ostrom","year":"2013","journal-title":"Neuro Oncol."},{"key":"2023050411183553900_CIT0054","first-page":"369","article-title":"Brain and other nervous system tumours","volume":"19\u201320","author":"Muir","year":"1994","journal-title":"Cancer Surv."},{"key":"2023050411183553900_CIT0055","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1111\/j.1749-6632.1990.tb32067.x","article-title":"Is brain cancer mortality increasing in industrial countries?","volume":"609","author":"Davis","year":"1990","journal-title":"Ann N Y Acad Sci."},{"issue":"20","key":"2023050411183553900_CIT0056","doi-asserted-by":"crossref","first-page":"1621","DOI":"10.1093\/jnci\/82.20.1621","article-title":"Increasing annual incidence of primary malignant brain tumors in the elderly","volume":"82","author":"Greig","year":"1990","journal-title":"J Natl Cancer Inst."},{"issue":"1","key":"2023050411183553900_CIT0057","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1215\/S1522851705000323","article-title":"Temporal trends in incidence of primary brain tumors in the United States, 1985\u20131999","volume":"8","author":"Hoffman","year":"2006","journal-title":"Neuro Oncol."},{"issue":"12","key":"2023050411183553900_CIT0058","doi-asserted-by":"crossref","first-page":"2918","DOI":"10.1002\/ijc.25517","article-title":"Fifty years of cancer incidence: CI5 I\u2013IX","volume":"127","author":"Parkin","year":"2010","journal-title":"Int J Cancer."}],"container-title":["Neuro-Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/neuro-oncology\/advance-article-pdf\/doi\/10.1093\/neuonc\/noac213\/46607326\/noac213.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/neuro-oncology\/article-pdf\/25\/5\/995\/50196471\/noac213.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/neuro-oncology\/article-pdf\/25\/5\/995\/50196471\/noac213.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,4]],"date-time":"2023-05-04T12:38:24Z","timestamp":1683203904000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/neuro-oncology\/article\/25\/5\/995\/6681116"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,9,1]]},"references-count":58,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2022,9,1]]},"published-print":{"date-parts":[[2023,5,4]]}},"URL":"https:\/\/doi.org\/10.1093\/neuonc\/noac213","relation":{},"ISSN":["1522-8517","1523-5866"],"issn-type":[{"value":"1522-8517","type":"print"},{"value":"1523-5866","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2023,5,1]]},"published":{"date-parts":[[2022,9,1]]}}}