{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,6]],"date-time":"2026-11-06T10:36:27Z","timestamp":1793961387783,"version":"4.8.0"},"reference-count":10,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","license":[{"start":{"date-parts":[[2021,4,7]],"date-time":"2021-04-07T00:00:00Z","timestamp":1617753600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neurosurg.","NEUROS"],"published-print":{"date-parts":[[2021,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>BACKGROUND<\/jats:title>\n                    <jats:p>Heterogeneous effect of endovascular aneurysm therapy has been observed across different anatomic locations. There is a paucity of data for stent-assisted coiling of middle cerebral artery (MCA) aneurysms.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>OBJECTIVE<\/jats:title>\n                    <jats:p>To present the results of the MCA aneurysm group from the Neuroform Atlas (Stryker Neurovascular) investigational device exemption (IDE) trial.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS<\/jats:title>\n                    <jats:p>The Atlas IDE trial is a prospective, multicenter, single-arm, open-label study of wide-neck aneurysms (neck\u00a0\u2265\u00a04 mm\u00a0or dome-to-neck ratio\u00a0&lt;\u00a02)\u00a0in the anterior circulation treated with the Neuroform Atlas Stent and approved coils. Follow-up was obtained immediately postprocedure and 2, 6, and 12 mo postoperatively. We herein describe safety and efficacy outcomes, and functional independence of the subjects with aneurysms from all segments of MCA.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS<\/jats:title>\n                    <jats:p>A total of 35 patients were included (27 MCA bifurcation, 5 M1, 3 M2). The mean aneurysm size was 6.0\u00a0\u00b1 1.8\u00a0mm, and the mean neck was 4.4\u00a0\u00b1 1.2\u00a0mm. Technical procedural success was achieved in all patients. A total of 26 patients had follow-up digital subtraction angiography available at 12 mo, with 80.8% (21\/26) having complete aneurysm occlusion. Twelve-month safety data were collected for 91.4% (32\/35), 8.5% (3\/35) had primary safety endpoint, all 3 major ischemic strokes. Mortality occurred in 2 patients beyond 30 d unrelated to procedure (1 gallbladder cancer and 1 fentanyl intoxication). At 1 yr, modified Rankin Score was 0 to 2 in 84.4% (27\/32), 3 in 9.4%, and 3 patients were missing. Approximately 5.7% (2\/35) of patients were retreated at 12 mo.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSION<\/jats:title>\n                    <jats:p>Stent-assisted coiling with the Neuroform Atlas Stent is a viable alternative to clipping for selected MCA aneurysms. Complete aneurysm occlusion rates have improved compared to historical data. Proper case selection can lead to acceptable endovascular results.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/neuros\/nyab090","type":"journal-article","created":{"date-parts":[[2021,2,27]],"date-time":"2021-02-27T15:07:53Z","timestamp":1614438473000},"page":"102-108","source":"Crossref","is-referenced-by-count":28,"title":["Neuroform Atlas Stent for Treatment of Middle Cerebral Artery Aneurysms: 1-Year Outcomes From Neuroform Atlas Stent Pivotal Trial"],"prefix":"10.1227","volume":"89","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7195-5806","authenticated-orcid":false,"given":"Ricardo A","family":"Hanel","sequence":"first","affiliation":[{"name":"Lyerly Neurosurgery, Jacksonville, Florida, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nam","family":"Yoon","sequence":"additional","affiliation":[{"name":"Lyerly Neurosurgery, Jacksonville, Florida, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4399-1142","authenticated-orcid":false,"given":"Eric","family":"Sauvageau","sequence":"additional","affiliation":[{"name":"Lyerly Neurosurgery, Jacksonville, Florida, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1797-5627","authenticated-orcid":false,"given":"Amin","family":"Aghaebrahim","sequence":"additional","affiliation":[{"name":"Lyerly Neurosurgery, Jacksonville, Florida, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eugene","family":"Lin","sequence":"additional","affiliation":[{"name":"Neuroscience Department, Bon Secours Mercy Health St. Vincent Medical Center, Toledo, Ohio, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashutosh P","family":"Jadhav","sequence":"additional","affiliation":[{"name":"The Stroke Institute, Department of Neurology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tudor G","family":"Jovin","sequence":"additional","affiliation":[{"name":"Cooper University Hospital Neurological Institute, Camden, New Jersey, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmad","family":"Khaldi","sequence":"additional","affiliation":[{"name":"WellStar Medical Group, Neurosurgery WellStar Health System, Marietta, Georgia, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rishi G","family":"Gupta","sequence":"additional","affiliation":[{"name":"WellStar Medical Group, Neurosurgery WellStar Health System, Marietta, Georgia, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Johnson","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Northshore University Health System, Chicago, Illinois, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donald","family":"Frei","sequence":"additional","affiliation":[{"name":"Radiology Imaging Associates, Swedish Medical Center, Englewood, Colorado, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Loy","sequence":"additional","affiliation":[{"name":"Department of Radiology and Medical Imaging, University of Virginia, Charlottesville, Virginia, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adel","family":"Malek","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Tufts Medical Center, Boston, Massachusetts, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3646-3635","authenticated-orcid":false,"given":"Gabor","family":"Toth","sequence":"additional","affiliation":[{"name":"Cerebrovascular Center, Cleveland Clinic, Cleveland, Ohio, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adnan","family":"Siddiqui","sequence":"additional","affiliation":[{"name":"SUNY University at Buffalo, Buffalo, New York, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Reavey-Cantwell","sequence":"additional","affiliation":[{"name":"Virginia Commonwealth University Medical Center, Richmond, Virginia, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4412-3152","authenticated-orcid":false,"given":"Ajith","family":"Thomas","sequence":"additional","affiliation":[{"name":"Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven W","family":"Hetts","sequence":"additional","affiliation":[{"name":"Interventional Neuroradiology, University of California San Francisco, San Francisco, California, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian T","family":"Jankowitz","sequence":"additional","affiliation":[{"name":"Cooper University Hospital, Camden, New Jersey, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Osama O","family":"Zaidat","sequence":"additional","affiliation":[{"name":"Neuroscience Department, Bon Secours Mercy Health St. Vincent Medical Center, Toledo, Ohio, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2021,7]]},"reference":[{"issue":"10","key":"bib1-20231011","doi-asserted-by":"crossref","first-page":"957","DOI":"10.1136\/neurintsurg-2019-015702","article-title":"Cerebral aneurysm treatment trends in National Inpatient Sample 2007-2016: endovascular therapies favored over surgery","volume":"12","author":"Wang","year":"2020","journal-title":"J Neurointerv 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