{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T14:26:49Z","timestamp":1790864809046,"version":"4.1.0"},"reference-count":47,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":["NEUROSURGERY","NEUROS"],"published-print":{"date-parts":[[2017,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    <jats:bold>BACKGROUND:<\/jats:bold>\n                    Classically used for treatment of orbital lesions, the lateral orbitotomy with cantholysis can be combined with a temporal craniectomy for lesions involving the middle cranial fossa.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>OBJECTIVE:<\/jats:bold>\n                    To present a single-center experience with the lateral orbitotomy approach for lesions involving the middle fossa.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>METHODS:<\/jats:bold>\n                    Twenty-five patients underwent lateral orbitotomies from April 2012 to July 2015. Excluding patients with solely intraorbital pathologies, 13 patients\u2019 clinical and radiographic records were retrospectively reviewed.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>RESULTS:<\/jats:bold>\n                    Signs\/symptoms in the 13 patients (ages 28-81) included proptosis (69%), decreased visual acuity (31%), diplopia (54%), and afferent pupillary defect (69%). Pathologies were meningioma (8), esthesioneuroblastoma, lymphoma, chordoma, Ewing's sarcoma, and squamous cell carcinoma. Surgical goals were maximal safe resection in 8 patients, palliative debulking in 3 patients, and cavernous sinus biopsy in 2 patients. In 8 patients for whom maximal resection was the goal, 2 had gross total resection, while 6 had near-total resection. All patients (3) for whom palliation was the goal had symptomatic improvement. Both cavernous sinus biopsies obtained diagnostic tissue without complications. All patients with proptosis (n = 9) and diplopia (n = 7), and 2 of 4 patients with decreased visual acuity had improvement in their symptoms. No patient reported worsening of their symptoms. Mean follow-up was 12 mo (2-30 mo). Complications included oculorrhea (1), pseudomeningocele (2), transient ptosis (2), and forehead numbness (1).\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>CONCLUSION:<\/jats:bold>\n                    The lateral orbitotomy is a promising approach for carefully selected lesions with involvement of both the lateral orbit and middle cranial fossa. It provides minimally invasive access for biopsy, decompression, or resection.\n                  <\/jats:p>","DOI":"10.1093\/neuros\/nyw045","type":"journal-article","created":{"date-parts":[[2017,2,7]],"date-time":"2017-02-07T19:12:16Z","timestamp":1486494736000},"page":"309-322","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":49,"title":["Lateral Orbitotomy Approach for Lesions Involving the Middle Fossa: A Retrospective Review of Thirteen Patients"],"prefix":"10.1227","volume":"80","author":[{"given":"Joseph D.","family":"Chabot","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, Univer-sity of Pittsburgh Medical Center, Pitts-burgh, Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul A.","family":"Gardner","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Univer-sity of Pittsburgh Medical Center, Pitts-burgh, Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S. Tonya","family":"Stefko","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nathan T.","family":"Zwagerman","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Univer-sity of Pittsburgh Medical Center, Pitts-burgh, Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan Carlos","family":"Fernandez- Miranda","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Univer-sity of Pittsburgh Medical Center, Pitts-burgh, Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2017,2]]},"reference":[{"key":"bib1-20240906","first-page":"193","article-title":"A modified kronlein operation","volume":"51","author":"Berke","year":"1953","journal-title":"Trans Am Ophthalmol Soc"},{"issue":"5","key":"bib2-20240906","doi-asserted-by":"crossref","first-page":"556","DOI":"10.3171\/jns.1976.44.5.0556","article-title":"Lateral microsurgical approach to intraorbital tumors","volume":"44","author":"Maroon","year":"1976","journal-title":"J Neurosurg"},{"issue":"7","key":"bib3-20240906","doi-asserted-by":"crossref","first-page":"1206","DOI":"10.1097\/00005537-200307000-00017","article-title":"Medial and lateral orbital wall surgery for balanced decompression in thyroid eye disease","volume":"113","author":"Graham","year":"2003","journal-title":"Laryngoscope"},{"issue":"4","key":"bib4-20240906","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1016\/j.otc.2011.06.011","article-title":"Orbit and orbital apex","volume":"44","author":"Robinson","year":"2011","journal-title":"Otolaryngol Clin North Am"},{"issue":"11","key":"bib5-20240906","doi-asserted-by":"crossref","first-page":"1170","DOI":"10.1089\/thy.2012.0272","article-title":"Rehabilitative orbital decompression for Graves\u2019 orbitopathy: risk factors influencing the new onset of diplopia in primary gaze, outcome and patients' satisfaction. 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