{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T06:52:25Z","timestamp":1789195945460,"version":"build-2803163510"},"reference-count":66,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["NEUROSURGERY","NEUROS"],"published-print":{"date-parts":[[2017,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    <jats:bold>BACKGROUND:<\/jats:bold>\n                    Decompression without fusion is a treatment option in patients with lumbar spinal stenosis (LSS) associated with stable low-grade degenerative spondylolisthesis (DS). A minimally invasive unilateral laminotomy (MIL) for \u201cover the top\u201d decompression might be a less destabilizing alternative to traditional open laminectomy (OL).\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>OBJECTIVE:<\/jats:bold>\n                    To review secondary fusion rates after open vs minimally invasive decompression surgery.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>METHODS:<\/jats:bold>\n                    We performed a literature search in Pubmed\/MEDLINE using the keywords \u201clumbar spondylolisthesis\u201d and \u201cdecompression surgery.\u201d All studies that separately reported the outcome of patients with LSS+DS that were treated by OL or MIL (transmuscular or subperiosteal route) were included in our systematic review and meta-analysis. The primary end point was secondary fusion rate. Secondary end points were total reoperation rate, postoperative progression of listhetic slip, and patient satisfaction.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>RESULTS:<\/jats:bold>\n                    We identified 37 studies (19 with OL, 18 with MIL), with a total of 1156 patients, that were published between 1983 and 2015. The studies\u2019 evidence was mostly level 3 or 4. Secondary fusion rates were 12.8% after OL and 3.3% after MIL; the total reoperation rates were 16.3% after OL and 5.8% after MIL. In the OL cohort, 72% of the studies reported a slip progression compared to 0% in the MIL cohort, respectively. After OL, satisfactory outcome was 62.7% compared to 76% after MIL.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>CONCLUSION:<\/jats:bold>\n                    In patients with LSS and DS, minimally invasive decompression is associated with lower reoperation and fusion rates, less slip progression, and greater patient satisfaction than open surgery.\n                  <\/jats:p>","DOI":"10.1093\/neuros\/nyw091","type":"journal-article","created":{"date-parts":[[2017,2,24]],"date-time":"2017-02-24T15:26:01Z","timestamp":1487949961000},"page":"355-367","source":"Crossref","is-referenced-by-count":119,"title":["Lumbar Spinal Stenosis Associated With Degenerative Lumbar Spondylolisthesis: A Systematic Review and Meta-analysis of Secondary Fusion Rates Following Open vs Minimally Invasive Decompression"],"prefix":"10.1227","volume":"80","author":[{"given":"Karsten","family":"Sch\u00f6ller","sequence":"first","affiliation":[{"name":"Weill Cornell Brain and Spine Center, Department of Neurological Surgery, Weill Cornell Medical College, New York Presbyterian Hospital, New York, New York"},{"name":"Department of Neurosurgery, Justus-Liebig University, Giessen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marjan","family":"Alimi","sequence":"additional","affiliation":[{"name":"Weill Cornell Brain and Spine Center, Department of Neurological Surgery, Weill Cornell Medical College, New York Presbyterian Hospital, New York, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guang-Ting","family":"Cong","sequence":"additional","affiliation":[{"name":"Weill Cornell Brain and Spine Center, Department of Neurological Surgery, Weill Cornell Medical College, New York Presbyterian Hospital, New York, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Christos","sequence":"additional","affiliation":[{"name":"Division of Biostatistics and Epidemiology, Department of Healthcare Policy and Research, Weill Cornell Medical College, New York, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roger","family":"H\u00e4rtl","sequence":"additional","affiliation":[{"name":"Weill Cornell Brain and Spine Center, Department of Neurological Surgery, Weill Cornell Medical College, New York Presbyterian Hospital, New York, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2017,3]]},"reference":[{"issue":"7","key":"bib1-20231011","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1016\/j.spinee.2009.03.016","article-title":"An evidence-based clinical guideline for the diagnosis and treatment of degenerative lumbar spondylolisthesis","volume":"9","author":"Watters","year":"2009","journal-title":"Spine J"},{"issue":"22","key":"bib2-20231011","doi-asserted-by":"crossref","first-page":"2257","DOI":"10.1056\/NEJMoa070302","article-title":"Surgical versus nonsurgical treatment for lumbar degenerative spondylolisthesis","volume":"356","author":"Weinstein","year":"2007","journal-title":"N Engl J Med"},{"issue":"6","key":"bib3-20231011","doi-asserted-by":"crossref","first-page":"1295","DOI":"10.2106\/JBJS.H.00913","article-title":"Surgical compared with nonoperative treatment for lumbar degenerative spondylolisthesis. 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