{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T17:51:41Z","timestamp":1786125101510,"version":"build-2736575974"},"reference-count":62,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["NEUROSURGERY","NEUROS"],"published-print":{"date-parts":[[2017,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    <jats:bold>BACKGROUND:<\/jats:bold>\n                    Spinal intradural arachnoid cysts are rare causes of radiculopathy or myelopathy. Treatment options include resection, fenestration, or cyst drainage.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>OBJECTIVE:<\/jats:bold>\n                    To classify intradural spinal arachnoid cysts and present results of their treatment.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>METHODS:<\/jats:bold>\n                    Among 1519 patients with spinal space occupying lesions, 130 patients demonstrated intradural arachnoid cysts. Neuroradiological and surgical features were reviewed and clinical data analyzed.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>RESULTS:<\/jats:bold>\n                    Twenty-one patients presented arachnoid cysts as a result of an inflammatory leptomeningeal reaction related to meningitis, subarachnoid hemorrhage, intrathecal injections, intradural surgery, or trauma, ie, secondary cysts. For the remaining 109 patients, no such history could be elucidated, ie, primary cysts. Forty-six percent of primary and 86% of secondary cysts were associated with syringomyelia. Patients presented after an average history of 53 \u00b1 88 months. There were 122 thoracic and 7 lumbar cysts plus 1 cervical cyst. Fifty-nine patients with primary and 15 patients with secondary cysts underwent laminotomies with complete or partial cyst resection and duraplasty. Mean follow-up was 57 \u00b1 52 months. In the first postoperative year, profound improvements for primary cysts were noted, in contrast to marginal changes for secondary cysts. Progression-free survival for 10 years following surgery was determined as 83% for primary compared to 15% for secondary cysts. Despite differences in clinical presentation, progression-free survival was almost identical for patients with or without syringomyelia.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>CONCLUSIONS:<\/jats:bold>\n                    Complete or partial resection leads to favorable short- and long-term results for primary arachnoid cysts. For secondary cysts, surgery can only provide clinical stabilization for a limited time due to the often extensive arachnoiditis.\n                  <\/jats:p>","DOI":"10.1093\/neuros\/nyx050","type":"journal-article","created":{"date-parts":[[2017,2,15]],"date-time":"2017-02-15T03:57:32Z","timestamp":1487131052000},"page":"217-229","source":"Crossref","is-referenced-by-count":53,"title":["A New Classification for Pathologies of Spinal Meninges\u2014Part 2: Primary and Secondary Intradural Arachnoid Cysts"],"prefix":"10.1227","volume":"81","author":[{"given":"J\u00f6rg","family":"Klekamp","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, Christlich-es Krankenhaus Quakenbr\u00fcck, Quaken-br\u00fcck, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2017,8]]},"reference":[{"key":"bib1-20231011","article-title":"New classification for pathologies of spinal meninges, part 1: dural cysts, dissections and ectasias","author":"Klekamp","journal-title":"Neurosurgery"},{"issue":"suppl 3","key":"bib4-20231011","doi-asserted-by":"crossref","first-page":"S329","DOI":"10.1007\/s00586-012-2373-1","article-title":"Intradural extramedullary primary hydatid cyst of the spine: a case report and review of literature","volume":"22","author":"Lotfinia","year":"2013","journal-title":"Eur Spine J."},{"issue":"3","key":"bib5-20231011","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1067\/cdr.2002.125402","article-title":"Magnetic resonance imaging of intraspinal cystic lesions: a pictorial review","volume":"31","author":"Evans","year":"2002","journal-title":"Curr Probl Diagn Radiol"},{"issue":"6","key":"bib6-20231011","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1007\/s00247-007-0463-8","article-title":"Differentiation between pediatric spinal arachnoid and epidermoid-dermoid cysts: is diffusion-weighted MRI useful?","volume":"37","author":"Kukreja","year":"2007","journal-title":"Pediatr Radiol"},{"issue":"2-3","key":"bib7-20231011","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1007\/BF02389320","article-title":"Cystic spinal cord tumors: magnetic resonance imaging correlated to histopathological findings","volume":"21","author":"Matsui","year":"1998","journal-title":"Neurosurg Rev"},{"issue":"3","key":"bib8-20231011","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1227\/NEU.0b013e31827fcc8f","article-title":"Treatment of syringomyelia related to nontraumatic arachnoid pathologies of the spinal canal","volume":"72","author":"Klekamp","year":"2013","journal-title":"Neurosurgery"},{"key":"bib9-20231011","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1080\/01621459.1958.10501452","article-title":"Nonparametric estimation from incomplete observations","volume":"53","author":"Kaplan","year":"1958","journal-title":"J Am Stat Assoc"},{"key":"bib10-20231011","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1016\/j.wneu.2015.09.058","article-title":"Intradural spinal arachnoid cyst: a long-term postlaminectomy complication: a case report and review of the literature","volume":"85","author":"Nath","year":"2016","journal-title":"World Neurosurg"},{"issue":"2","key":"bib11-20231011","doi-asserted-by":"crossref","first-page":"276","DOI":"10.3171\/jns.1988.69.2.0276","article-title":"The fine anatomy of the human spinal meninges. 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