{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T22:27:13Z","timestamp":1789165633378,"version":"build-2803163510"},"reference-count":74,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","license":[{"start":{"date-parts":[[2018,7,12]],"date-time":"2018-07-12T00:00:00Z","timestamp":1531353600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neurosurg.","NEUROS"],"published-print":{"date-parts":[[2019,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>BACKGROUND<\/jats:title>\n                    <jats:p>The authors present cystic epithelial masses in the suprasellar region which on histopathology revealed 4 mixed tumors having simple cuboidal epithelium of Rathke's Cleft Cyst (RCC) elements trapped within pituitary adenoma, epidermoid cyst, dermoid cyst, and papillary craniopharyngioma respectively.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>OBJECTIVE<\/jats:title>\n                    <jats:p>To highlight the developmental theory of ectodermal continuum in the realm of suprasellar epithelial cystic lesions and examines the cardinal aspects that distinguish RCC from its confounder, ciliary craniopharyngioma.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS<\/jats:title>\n                    <jats:p>The authors performed a medical chart review on 4 patients who had coexisting RCC with craniopharyngioma, pituitary adenoma, suprasellar dermoid, and epidermoid cysts.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS<\/jats:title>\n                    <jats:p>This series of unique suprasellar lesions elucidate the spectrum of cases from Rathke's cyst to other suprasellar epithelial cysts including a recently identified clinical entity called ciliary craniopharyngioma, which authors feel is a misnomer. The authors also report the first case of ruptured dermoid cyst admixed with elements of Rathke's cyst elements and xanthogranuloma in neurosurgical literature.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSION<\/jats:title>\n                    <jats:p>We propose that the new entity of ciliary craniopharyngioma could be just another variant of RCC elements nested within a typical papillary or adamantinomatous lesion. Further study is warranted to understand the implications of natural history with tumors containing RCC elements.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/neuros\/nyy285","type":"journal-article","created":{"date-parts":[[2018,6,3]],"date-time":"2018-06-03T23:06:14Z","timestamp":1528067174000},"page":"180-188","source":"Crossref","is-referenced-by-count":10,"title":["Intratumoral Rathke's Cleft Cyst Remnants Within Craniopharyngioma, Pituitary Adenoma, Suprasellar Dermoid, and Epidermoid Cysts: A Ubiquitous Signature of Ectodermal Lineage or a Transitional Entity?"],"prefix":"10.1227","volume":"85","author":[{"given":"Sunil","family":"Manjila","sequence":"first","affiliation":[{"name":"Department of Neurological Surgery, The Neurological Institute, University Hospitals Cleveland Medical Center, Cleveland, Ohio"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nadine El","family":"Asmar","sequence":"additional","affiliation":[{"name":"Department of En-docrinology, University Hospitals Cleve-land Medical Center, Cleveland, Ohio"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin M","family":"Vidalis","sequence":"additional","affiliation":[{"name":"Department of Neurological Surgery, University of New Mexico Hospitals, Albuquerque, New Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernando","family":"Alonso","sequence":"additional","affiliation":[{"name":"Department of Neurological Surgery, The Neurological Institute, University Hospitals Cleveland Medical Center, Cleveland, Ohio"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gagandeep","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Pathology, University Hospitals Cleveland Medical Center, Cleveland, Ohio"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karthik","family":"Vadamalai","sequence":"additional","affiliation":[{"name":"Department of Neurological Surgery, The Neurological Institute, University Hospitals Cleveland Medical Center, Cleveland, Ohio"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark L","family":"Cohen","sequence":"additional","affiliation":[{"name":"Department of Pathology, University Hospitals Cleveland Medical Center, Cleveland, Ohio"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicholas C","family":"Bambakidis","sequence":"additional","affiliation":[{"name":"Department of Neurological Surgery, The Neurological Institute, University Hospitals Cleveland Medical Center, Cleveland, Ohio"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Baha M","family":"Arafah","sequence":"additional","affiliation":[{"name":"Department of En-docrinology, University Hospitals Cleve-land Medical Center, Cleveland, Ohio"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Warren R","family":"Selman","sequence":"additional","affiliation":[{"name":"Department of Neurological Surgery, The Neurological Institute, University Hospitals Cleveland Medical Center, Cleveland, Ohio"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2019,8]]},"reference":[{"issue":"12","key":"bib1-20231011","first-page":"745","article-title":"Rathke's cleft and its cysts","volume":"55","author":"Bayoumi","year":"1948","journal-title":"Edinb Med J"},{"issue":"1","key":"bib2-20231011","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1097\/00006123-199801000-00003","article-title":"Transsphenoidal management of 28 symptomatic Rathke's cleft cysts, with special reference to visual and hormonal recovery","volume":"42","author":"el-Mahdy","year":"1998","journal-title":"Neurosurgery"},{"issue":"4","key":"bib3-20231011","doi-asserted-by":"crossref","first-page":"632","DOI":"10.1227\/00006123-199410000-00008","article-title":"Radiological study of symptomatic Rathke's cleft cysts","volume":"35","author":"Oka","year":"1994","journal-title":"Neurosurgery"},{"issue":"11","key":"bib4-20231011","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.2176\/nmc.29.1039","article-title":"Symptomatic Rathke's cleft cyst simulating arachnoid cyst","volume":"29","author":"Onda","year":"1989","journal-title":"Neurol. 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