{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T17:45:46Z","timestamp":1786124746071,"version":"build-2736575974"},"reference-count":43,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","license":[{"start":{"date-parts":[[2018,9,20]],"date-time":"2018-09-20T00:00:00Z","timestamp":1537401600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"name":"NCI Cancer Center Support","award":["5P30CA124435"],"award-info":[{"award-number":["5P30CA124435"]}]},{"DOI":"10.13039\/100000002","name":"NIH","doi-asserted-by":"publisher","award":["UL1 RR025744"],"award-info":[{"award-number":["UL1 RR025744"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000097","name":"NCRR","doi-asserted-by":"publisher","award":["UL1 RR025744"],"award-info":[{"award-number":["UL1 RR025744"]}],"id":[{"id":"10.13039\/100000097","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neurosurg.","NEUROS"],"published-print":{"date-parts":[[2019,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>BACKGROUND<\/jats:title>\n                    <jats:p>An understanding of the hearing outcomes is needed for treatment counseling for patients with vestibular schwannomas (VS).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>OBJECTIVE<\/jats:title>\n                    <jats:p>To determine long-term hearing results following stereotactic radiosurgery (SRS) for VS and identify any influential variables.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS<\/jats:title>\n                    <jats:p>Tertiary hospital retrospective cohort.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS<\/jats:title>\n                    <jats:p>\n                      There were 579 tumors (576 patients) treated with SRS. Eighty-two percent (473) of tumors had \u22651 yr and 59% (344 \u22653 yr follow-up. In the 244 tumor ears, with measurable hearing before SRS who were followed \u22651 yr, 14% (31) had improved hearing, 13% (29) unchanged hearing, and 74% (158) had worsened hearing. In 175 patients with \u22653 yr follow-up and who had measurable hearing pretreatment, 6% (11 ears) improved hearing, 31% (54 ears) unchanged hearing, and 63% (110 ears) had worsened hearing. Patients with tumors with larger target volumes (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u00a0=\u00a0.040) and with neurofibromatosis type 2 (NF2;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u00a0=\u00a0.017) were associated with poorer hearing (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u00a0=\u00a0.040). Patients with word recognition scores (WRS) of 50% or poorer had tumors with a larger volume (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u00a0=\u00a0.0002), larger linear size (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u00a0=\u00a0.032), and NF2 (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u00a0=\u00a0.045). Traditionally reported hearing outcomes using the Gardner Robertson maintenance of PTA \u226450 db or WRS \u226550% were 48% at 3 yr, which overestimates hearing outcomes compared to the above reporting standards.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSION<\/jats:title>\n                    <jats:p>Hearing declines over time in VS treated with SRS in a high proportion of cases. The frequency and magnitude of long-term hearing decline following SRS argues against prophylactic radiation for small tumors in hearing ears with undetermined growth behavior.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/neuros\/nyy407","type":"journal-article","created":{"date-parts":[[2018,8,1]],"date-time":"2018-08-01T15:13:36Z","timestamp":1533136416000},"page":"550-559","source":"Crossref","is-referenced-by-count":34,"title":["Long-Term Hearing Outcomes Following Stereotactic Radiosurgery in Vestibular Schwannoma Patients\u2014A Retrospective Cohort Study"],"prefix":"10.1227","volume":"85","author":[{"given":"Peter L","family":"Santa Maria","sequence":"first","affiliation":[{"name":"Department of Otolaryngology, Head and Neck Surgery, Stanford University, Palo Alto, California"},{"name":"Department of Ear Sciences, The University of Western Australia, Nedlands, Australia"},{"name":"Ear Science Institute Australia, Subiaco, 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California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chloe","family":"Santa Maria","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Head and Neck Surgery, Stanford University, Palo Alto, California"},{"name":"Department of Ear Sciences, The University of Western Australia, Nedlands, Australia"},{"name":"Ear Science Institute Australia, Subiaco, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin","family":"Murray","sequence":"additional","affiliation":[{"name":"School of Population and Global Health, The University of Western Australia, Nedlands, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven D","family":"Chang","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Stanford University, Stanford, California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nikolas 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