{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T02:12:53Z","timestamp":1793239973357,"version":"4.5.0"},"reference-count":20,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2005,10]]},"DOI":"10.1227\/01.neu.0000175856.31210.58","type":"journal-article","created":{"date-parts":[[2005,10,20]],"date-time":"2005-10-20T10:00:49Z","timestamp":1129802449000},"page":"759-763","source":"Crossref","is-referenced-by-count":185,"title":["Clinical Significance of Heterotopic Ossification in Cervical Disc Replacement: A Prospective Multicenter Clinical Trial"],"prefix":"10.1227","volume":"57","author":[{"given":"Clarence","family":"Leung","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adrian Th.","family":"Casey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan","family":"Goffin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierre","family":"Kehr","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Klaus","family":"Liebig","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bengt","family":"Lind","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlo","family":"Logroscino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincent","family":"Pointillart","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-17-20230406","first-page":"153","article-title":"Heterotopic bone after hip arthroplasty. Defining the patient at risk.","author":"Ahrengart","year":"1993","journal-title":"Clin Orthop Relat Res"},{"key":"R2-17-20230406","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/S0883-5403(87)80032-3","article-title":"Myositis ossificans after total hip replacement and perioperative muscle ischemia.","volume":"2","author":"Ahrengart","year":"1987","journal-title":"J Arthroplasty"},{"key":"R3-17-20230406","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1302\/0301-620X.57B1.36","article-title":"Observations on the induction of bone in soft tissues.","volume":"57","author":"Chalmers","year":"1975","journal-title":"J Bone Joint Surg Br"},{"key":"R4-17-20230406","doi-asserted-by":"crossref","first-page":"995","DOI":"10.1097\/00007632-199604150-00015","article-title":"Results of disc prosthesis after a minimum follow-up period of 2 years.","volume":"21","author":"Cinotti","year":"1996","journal-title":"Spine"},{"key":"R5-17-20230406","doi-asserted-by":"crossref","first-page":"1139","DOI":"10.3928\/0147-7447-20011201-11","article-title":"Indomethacin versus radiation therapy for heterotopic ossification after hip arthroplasty.","volume":"24","author":"D\u2019Lima","year":"2001","journal-title":"Orthopedics"},{"key":"R6-17-20230406","first-page":"102","article-title":"Experimental induction of heterotopic bone.","author":"Ekelund","year":"1991","journal-title":"Clin Orthop Relat Res"},{"key":"R7-17-20230406","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1023\/A:1024830213832","article-title":"Prevention of heterotopic ossification after total hip replacement with NSAIDs.","volume":"25","author":"Fijn","year":"2003","journal-title":"Pharm World Sci"},{"key":"R8-17-20230406","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1302\/0301-620X.73B2.1900841","article-title":"Heterotopic bone formation after hip replacement. The influence of the type of osteoarthritis.","volume":"73","author":"Goel","year":"1991","journal-title":"J Bone Joint Surg Br"},{"key":"R9-17-20230406","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1097\/00006123-200209000-00048","article-title":"Preliminary clinical experience with the Bryan Cervical Disc Prosthesis.","volume":"51","author":"Goffin","year":"2002","journal-title":"Neurosurgery"},{"key":"R10-17-20230406","doi-asserted-by":"crossref","first-page":"2673","DOI":"10.1097\/01.BRS.0000099392.90849.AA","article-title":"Intermediate follow-up after treatment of degenerative disc disease with the Bryan Cervical Disc Prosthesis: Single-level and bi-level.","volume":"28","author":"Goffin","year":"2003","journal-title":"Spine"},{"key":"R11-17-20230406","doi-asserted-by":"crossref","first-page":"1842","DOI":"10.1097\/00007632-199408150-00009","article-title":"A multicenter retrospective study of the clinical results of the LINK SB Charite intervertebral prosthesis. The initial European experience.","volume":"19","author":"Griffith","year":"1994","journal-title":"Spine"},{"key":"R12-17-20230406","doi-asserted-by":"crossref","first-page":"409","DOI":"10.5435\/00124635-200211000-00005","article-title":"Heterotopic ossification after hip and knee arthroplasty: Risk factors, prevention, and treatment.","volume":"10","author":"Iorio","year":"2002","journal-title":"J Am Acad Orthop Surg"},{"key":"R13-17-20230406","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1097\/00024720-200308000-00010","article-title":"Classification of heterotopic ossification (HO) in artificial disk replacement.","volume":"16","author":"McAfee","year":"2003","journal-title":"J Spinal Disord Tech"},{"key":"R14-17-20230406","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1046\/j.1445-2197.2003.02647.x","article-title":"Effects of heterotopic bone formation on outcome after hip arthroplasty.","volume":"73","author":"Neal","year":"2003","journal-title":"Aust N Z J Surg"},{"key":"R15-17-20230406","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1016\/S0883-5403(03)00265-1","article-title":"The efficacy of 500 CentiGray radiation in the prevention of heterotopic ossification after total hip arthroplasty: A prospective, randomized, pilot study.","volume":"18","author":"Padgett","year":"2003","journal-title":"J Arthroplasty"},{"key":"R16-17-20230406","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1007\/BF00932162","article-title":"Factors associated with heterotopic bone formation following total hip replacement.","volume":"108","author":"Pedersen","year":"1989","journal-title":"Arch Orthop Trauma Surg"},{"key":"R17-17-20230406","first-page":"269","article-title":"Pathologic bone formation.","author":"Puzas","year":"1989","journal-title":"Clin Orthop Relat Res"},{"key":"R18-17-20230406","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/S0883-5403(03)00279-1","article-title":"Celecoxib versus indomethacin in the prevention of heterotopic ossification after total hip arthroplasty.","volume":"19","author":"Romano","year":"2004","journal-title":"J Arthroplasty"},{"key":"R19-17-20230406","doi-asserted-by":"crossref","first-page":"760","DOI":"10.1016\/S0883-5403(03)00194-3","article-title":"Heterotopic ossification after total knee arthroplasty.","volume":"18","author":"Toyoda","year":"2003","journal-title":"J Arthroplasty"},{"key":"R20-17-20230406","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1302\/0301-620X.74B2.1544955","article-title":"Heterotopic ossification after spinal cord injury. Epidemiology and risk factors.","volume":"74","author":"Wittenberg","year":"1992","journal-title":"J Bone Joint Surg Br"}],"container-title":["Neurosurgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/neurosurgery\/article-pdf\/57\/4\/759\/32571395\/00006123-200510000-00017.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/www.ovid.com\/00006123-200510000-00017","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T16:39:58Z","timestamp":1786120798000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/00006123-200510000-00017"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,10]]},"references-count":20,"aliases":["10.1093\/neurosurgery\/57.4.759"],"journal-issue":{"issue":"4","published-print":{"date-parts":[[2005]]}},"URL":"https:\/\/doi.org\/10.1227\/01.neu.0000175856.31210.58","relation":{},"ISSN":["0148-396X"],"issn-type":[{"value":"0148-396X","type":"print"}],"subject":[],"published":{"date-parts":[[2005,10]]}}}