{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T23:48:22Z","timestamp":1791330502863,"version":"4.3.1"},"reference-count":41,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2024,11,11]],"date-time":"2024-11-11T00:00:00Z","timestamp":1731283200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"ALF-agreement","award":["ALFGBG-965941"],"award-info":[{"award-number":["ALFGBG-965941"]}]},{"name":"The Swedish Cancer Society","award":["21 1580Pj01H"],"award-info":[{"award-number":["21 1580Pj01H"]}]},{"DOI":"10.13039\/100016669","name":"The Sj\u00f6berg Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100016669","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,6,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Malignant brain tumors often lead to death. While improving future treatments is essential, end-of-life care must also be addressed. To ensure equitable palliative care, understanding the place of death is crucial, as disparities may lead to inequity of care. This study aims to identify the place of death in adults with malignant brain tumors in Sweden, and the potential associations with official palliative care status by the ICD-10 code Z51.5, sociodemographic factors, health service characteristics, and healthcare service utilization.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>A population-level registry study examined the place of death among adults who died of malignant brain tumors in Sweden from 2013 to 2019. Descriptive statistics, univariable, and multivariable binary logistic regression analyses were performed.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>We identified 3,888 adults who died from malignant brain tumors. Of these, 64.4% did not receive an official palliative care status. Specialized palliative care was not utilized in 57.2% at the place of death and in 80% of nursing home deaths. In the last month of life, 53.5% of hospital deaths involved 1 transfer, while 41.8% had 2 or more transfers. The odds ratio (OR) of dying in hospital versus at home was higher, with 2 or more transfers (OR 0.63 [0.40, 0.99]). The OR of dying in a hospital versus at home showed significant regional differences.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Despite the severity of their diagnosis, only a minority of patients utilized specialized palliative services at death, and this varied by the place of death. Significant regional disparities were found between hospital and home deaths, indicating unequal end-of-life palliative care in this patient group.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/nop\/npae113","type":"journal-article","created":{"date-parts":[[2024,11,11]],"date-time":"2024-11-11T16:09:46Z","timestamp":1731341386000},"page":"511-519","source":"Crossref","is-referenced-by-count":4,"title":["Disparities in end-of-life care and place of death in people with malignant brain tumors\u2014A Swedish registry study"],"prefix":"10.1093","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1737-3359","authenticated-orcid":false,"given":"Anneli","family":"Ozanne","sequence":"first","affiliation":[{"name":"Department of Neurology, Sahlgrenska University Hospital , Gothenburg,","place":["Sweden"]},{"name":"Institute of Health and Care Sciences, Sahlgrenska Academy, University of Gothenburg , Gothenburg,","place":["Sweden"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2429-8705","authenticated-orcid":false,"given":"Joakim","family":"\u00d6hl\u00e9n","sequence":"additional","affiliation":[{"name":"Centre for Person-centred Care (GPCC), Sahlgrenska Academy, University of Gothenburg , Gothenburg,","place":["Sweden"]},{"name":"Institute of Health and Care Sciences, Sahlgrenska Academy, University of Gothenburg , Gothenburg,","place":["Sweden"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4998-0324","authenticated-orcid":false,"given":"Stina","family":"Nyblom","sequence":"additional","affiliation":[{"name":"Institute of Medicine, Sahlgrenska Academy, University of Gothenburg , Gothenburg,","place":["Sweden"]},{"name":"Palliative Centre, Sahlgrenska University Hospital , V\u00e4stra Fr\u00f6lunda,","place":["Sweden"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2860-9331","authenticated-orcid":false,"given":"Asgeir Store","family":"Jakola","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Sahlgrenska University Hospital , Gothenburg,","place":["Sweden"]},{"name":"Department of Clinical Neuroscience, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg , Gothenburg,","place":["Sweden"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4171-2672","authenticated-orcid":false,"given":"Anja","family":"Smits","sequence":"additional","affiliation":[{"name":"Department of Clinical Neuroscience, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg , Gothenburg,","place":["Sweden"]},{"name":"Department of Neurology, Sahlgrenska University Hospital , Gothenburg,","place":["Sweden"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3660-6306","authenticated-orcid":false,"given":"Cecilia","family":"Larsdotter","sequence":"additional","affiliation":[{"name":"Department of Nursing Science, Sophiahemmet University , Stockholm,","place":["Sweden"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2024,11,11]]},"reference":[{"issue":"4","key":"2025060501015410900_CIT0001","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1016\/j.jpainsymman.2012.09.013","article-title":"Quality indicators for palliative care: update of a systematic review","volume":"46","author":"De Roo","year":"2013","journal-title":"J Pain Symptom Manage."},{"issue":"4","key":"2025060501015410900_CIT0002","doi-asserted-by":"crossref","first-page":"e93762","DOI":"10.1371\/journal.pone.0093762","article-title":"Actual and preferred place of death of home-dwelling patients in four European countries: making sense of quality indicators","volume":"9","author":"De Roo","year":"2014","journal-title":"PLoS One."},{"issue":"7","key":"2025060501015410900_CIT0003","doi-asserted-by":"crossref","first-page":"744","DOI":"10.1177\/1403494815595774","article-title":"A population-level study of place of death and associated factors in Sweden","volume":"43","author":"H\u00e5kanson","year":"2015","journal-title":"Scand J Public Health."},{"issue":"18","key":"2025060501015410900_CIT0004","doi-asserted-by":"crossref","first-page":"26323524241238232","DOI":"10.1177\/26323524241238232","article-title":"Trends in the place of death in Sweden from 2013 to 2019\u2013disclosing prerequisites for palliative care","volume":"16","author":"Larsdotter","year":"2024","journal-title":"Palliat Care Soc Pract"},{"issue":"17","key":"2025060501015410900_CIT0005","doi-asserted-by":"crossref","first-page":"26323524231156944","DOI":"10.1177\/26323524231156944","article-title":"\u201cThe beauty and the less beautiful\u201d: exploring the meanings of dying at \u201chome\u201d among community and practitioner representatives and advocates across Canada","volume":"14","author":"Funk","year":"2023","journal-title":"Palliat Care Soc Pract"},{"issue":"6","key":"2025060501015410900_CIT0006","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1111\/ajco.12678","article-title":"End-of-life care: where do cancer patients want to die? A systematic review","volume":"13","author":"Nilsson","year":"2017","journal-title":"Asia Pac J Clin Oncol"},{"issue":"4","key":"2025060501015410900_CIT0007","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1177\/1403494817751329","article-title":"Public awareness of palliative care in Sweden","volume":"46","author":"Westerlund","year":"2018","journal-title":"Scand J Public Health."},{"issue":"3","key":"2025060501015410900_CIT0008","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1089\/jpm.2000.3.287","article-title":"Place of care in advanced cancer: a qualitative systematic literature review of patient preferences","volume":"3","author":"Higginson","year":"2000","journal-title":"J Palliat Med."},{"issue":"12","key":"2025060501015410900_CIT0009","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1007\/s11910-021-01152-9","article-title":"Epidemiology of brain and other CNS tumors","volume":"21","author":"Ostrom","year":"2021","journal-title":"Curr Neurol Neurosci Rep."},{"issue":"12 Suppl 2","key":"2025060501015410900_CIT0010","doi-asserted-by":"crossref","first-page":"iv1","DOI":"10.1093\/neuonc\/noaa200","article-title":"CBTRUS statistical report: primary brain and other central nervous system tumors diagnosed in the United States in 2013\u20132017","volume":"22","author":"Ostrom","year":"2020","journal-title":"Neuro Oncol"},{"issue":"1","key":"2025060501015410900_CIT0011","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1093\/neuonc\/nov249","article-title":"Years of potential life lost for brain and CNS tumors relative to other cancers in adults in the United States, 2010","volume":"18","author":"Rouse","year":"2016","journal-title":"Neuro Oncol"},{"issue":"Suppl 4","key":"2025060501015410900_CIT0012","doi-asserted-by":"crossref","first-page":"iv1","DOI":"10.1093\/neuonc\/nov189","article-title":"CBTRUS statistical report: primary brain and central nervous system tumors diagnosed in the United States in 2008-2012","volume":"17","author":"Ostrom","year":"2015","journal-title":"Neuro Oncol"},{"issue":"4","key":"2025060501015410900_CIT0013","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1007\/s11764-017-0602-7","article-title":"Life beyond a diagnosis of glioblastoma: a systematic review of the literature","volume":"11","author":"Gately","year":"2017","journal-title":"J Cancer Surviv"},{"issue":"1","key":"2025060501015410900_CIT0014","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1007\/s11060-008-9670-x","article-title":"End of life issues in brain tumor patients","volume":"91","author":"Pace","year":"2009","journal-title":"J Neurooncol."},{"issue":"11","key":"2025060501015410900_CIT0015","doi-asserted-by":"crossref","first-page":"1413","DOI":"10.2147\/NDT.S65874","article-title":"Psychiatric symptoms in glioma patients: from diagnosis to management","volume":"10","author":"Boele","year":"2015","journal-title":"Neuropsychiatr Dis Treat."},{"issue":"4","key":"2025060501015410900_CIT0016","doi-asserted-by":"crossref","first-page":"989","DOI":"10.3171\/2015.4.JNS15194","article-title":"Quality of survival the 1st year with glioblastoma: a longitudinal study of patient-reported quality of life","volume":"124","author":"Sagberg","year":"2016","journal-title":"J Neurosurg."},{"issue":"1","key":"2025060501015410900_CIT0017","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1111\/ane.13625","article-title":"Quality of life in patients with glioblastoma and their relatives","volume":"146","author":"St\u00e5hl","year":"2022","journal-title":"Acta Neurol Scand."},{"issue":"5","key":"2025060501015410900_CIT0018","first-page":"1","article-title":"Sweden health system review","volume":"14","author":"Anell","year":"2012","journal-title":"Health Syst Transit"},{"key":"2025060501015410900_CIT0019","author":"WHO"},{"issue":"2","key":"2025060501015410900_CIT0020","doi-asserted-by":"crossref","first-page":"161","DOI":"10.3109\/0284186X.2013.865079","article-title":"Implications of patients\u2019 socioeconomic status\u2013what oncologists should be aware of","volume":"53","author":"Cavalli-Bj\u00f6rkman","year":"2014","journal-title":"Acta Oncol."},{"issue":"4","key":"2025060501015410900_CIT0021","doi-asserted-by":"crossref","first-page":"e001248","DOI":"10.1136\/bmjopen-2012-001248","article-title":"Equal cancer treatment regardless of education level and family support? A qualitative study of oncologists\u2019 decision-making","volume":"2","author":"Cavalli-Bj\u00f6rkman","year":"2012","journal-title":"BMJ Open"},{"issue":"7","key":"2025060501015410900_CIT0022","doi-asserted-by":"crossref","first-page":"874","DOI":"10.1080\/0284186X.2022.2062681","article-title":"Advanced cancer and concomitant dementia: access to specialized palliative care, emergency room, hospital care, and place of death","volume":"61","author":"F\u00fcrst","year":"2022","journal-title":"Acta Oncol."},{"key":"2025060501015410900_CIT0023","author":"National Board of Health and Welfare S, Sweden"},{"key":"2025060501015410900_CIT0024","author":"Regeringskansliet"},{"key":"2025060501015410900_CIT0025","author":"Regionala cancercentrum i samverkan [Regional Cancer Center in collaboration] SG, Sweden"},{"issue":"11","key":"2025060501015410900_CIT0026","doi-asserted-by":"crossref","first-page":"e588","DOI":"10.1016\/S1470-2045(18)30415-7","article-title":"Integration of oncology and palliative care: a Lancet Oncology Commission","volume":"19","author":"Kaasa","year":"2018","journal-title":"Lancet Oncol."},{"key":"2025060501015410900_CIT0027","doi-asserted-by":"crossref","DOI":"10.1093\/acprof:oso\/9780199599400.001.0001","volume-title":"A Public Health Perspective on End of Life Care","author":"Cohen","year":"2012"},{"issue":"1","key":"2025060501015410900_CIT0028","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1177\/0269216313489367","article-title":"How many people need palliative care? A study developing and comparing methods for population-based estimates","volume":"28","author":"Murtagh","year":"2014","journal-title":"Palliat Med."},{"issue":"6","key":"2025060501015410900_CIT0029","doi-asserted-by":"crossref","first-page":"e330","DOI":"10.1016\/S1470-2045(17)30345-5","article-title":"European Association for Neuro-Oncology (EANO) guidelines for palliative care in adults with glioma","volume":"18","author":"Pace","year":"2017","journal-title":"Lancet Oncol."},{"key":"2025060501015410900_CIT0030","author":"samverkan Rci"},{"key":"2025060501015410900_CIT0031","author":"Mikkelsen"},{"issue":"8","key":"2025060501015410900_CIT0032","doi-asserted-by":"crossref","first-page":"900","DOI":"10.1177\/0269216319847089","article-title":"What socio-economic factors determine place of death for people with life-limiting illness? A systematic review and appraisal of methodological rigour","volume":"33","author":"Neergaard","year":"2019","journal-title":"Palliat Med."},{"issue":"3","key":"2025060501015410900_CIT0033","first-page":"107","article-title":"A population-based conceptual framework for evaluating the role of healthcare services in place of death","volume":"6","author":"Gao","year":"2018","journal-title":"Healthcare (Basel, Switzerland)"},{"issue":"1","key":"2025060501015410900_CIT0034","doi-asserted-by":"crossref","first-page":"e11","DOI":"10.1016\/j.jpainsymman.2020.09.043","article-title":"Were clinical routines for good end-of-life care maintained in hospitals and nursing homes during the first three months of the outbreak of COVID-19? A national register study","volume":"61","author":"Martinsson","year":"2021","journal-title":"J Pain Symptom Manage."},{"issue":"1","key":"2025060501015410900_CIT0035","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1007\/s11060-014-1360-2","article-title":"Patterns of care at end of life for people with primary intracranial tumors: lessons learned","volume":"117","author":"Alturki","year":"2014","journal-title":"J Neurooncol."},{"issue":"2","key":"2025060501015410900_CIT0036","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/j.jpainsymman.2016.09.008","article-title":"Frequency and predictors of acute hospitalization before death in patients with glioblastoma","volume":"53","author":"Diamond","year":"2017","journal-title":"J Pain Symptom Manage."},{"issue":"1","key":"2025060501015410900_CIT0037","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1186\/s12904-022-01022-2","article-title":"Acute healthcare utilization in end-of-life among Swedish brain tumor patients\u2013a population based register study","volume":"21","author":"Lindskog","year":"2022","journal-title":"BMC Palliat Care"},{"issue":"4","key":"2025060501015410900_CIT0038","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1200\/JCO.2014.57.3568","article-title":"Emergency department attendance by patients with cancer in their last month of life: a systematic review and meta-analysis","volume":"33","author":"Henson","year":"2015","journal-title":"J Clin Oncol."},{"issue":"6","key":"2025060501015410900_CIT0039","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1080\/0284186X.2020.1736335","article-title":"Inequity in palliative care service full utilisation among patients with advanced cancer: a retrospective Cohort study","volume":"59","author":"D\u2019Angelo","year":"2020","journal-title":"Acta Oncol."},{"issue":"1","key":"2025060501015410900_CIT0040","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1186\/s12904-021-00736-z","article-title":"Socioeconomy as a prognostic factor for location of death in Swedish palliative cancer patients","volume":"20","author":"Nilsson","year":"2021","journal-title":"BMC Palliat Care"},{"issue":"2","key":"2025060501015410900_CIT0041","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1038\/nrclinonc.2013.217","article-title":"End-of-life care--what do cancer patients want","volume":"11","author":"Khan","year":"2014","journal-title":"Nat Rev Clin Oncol."}],"container-title":["Neuro-Oncology Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/nop\/advance-article-pdf\/doi\/10.1093\/nop\/npae113\/60964068\/npae113.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/nop\/article-pdf\/12\/3\/511\/60964068\/npae113.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/nop\/article-pdf\/12\/3\/511\/60964068\/npae113.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,5]],"date-time":"2025-06-05T05:02:08Z","timestamp":1749099728000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/nop\/article\/12\/3\/511\/7889356"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11,11]]},"references-count":41,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2024,11,11]]},"published-print":{"date-parts":[[2025,6,4]]}},"URL":"https:\/\/doi.org\/10.1093\/nop\/npae113","relation":{},"ISSN":["2054-2577","2054-2585"],"issn-type":[{"value":"2054-2577","type":"print"},{"value":"2054-2585","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2025,6]]},"published":{"date-parts":[[2024,11,11]]}}}