{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T20:12:59Z","timestamp":1778271179313,"version":"3.51.4"},"reference-count":18,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2025,9,26]],"date-time":"2025-09-26T00:00:00Z","timestamp":1758844800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"name":"BONFOR"},{"name":"Medical Faculty of the University of Bonn","award":["2024-1A-03"],"award-info":[{"award-number":["2024-1A-03"]}]},{"name":"Neuro-aCSis Bonn Neuroscience Clinician Scientist Program","award":["2024-12-07"],"award-info":[{"award-number":["2024-12-07"]}]},{"DOI":"10.13039\/501100002347","name":"Federal Ministry of Education and Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002347","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002347","name":"BMBF","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002347","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,4,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>High-field (HF) MRI is a standard diagnostic tool for brain cancer, but its high cost and technical demands limit accessibility in low- and middle-income countries. Recent advancements in ultra-low field (ULF) MRI technology, including the development of portable scanners, offer a promising solution to these challenges. This study evaluates the diagnostic capabilities of ULF-MRI in detecting brain cancer and compares radiological evaluation using ULF- with HF-MRI.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Consecutive patients with suspected or confirmed brain tumors undergoing routine 3T HF-MRI at the University Hospital Bonn were recruited for this study and underwent ULF-MRI. Eligible patients were at least 18 years old and had MRI-abnormalities in the HF-MRI. The 0.064 Tesla Swoop portable MR Imaging System was utilized. HF-MRI and ULF-MRI scans were independently evaluated by two experienced neuroradiologists and results were compared.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Thirteen patients were recruited, of whom 11 (85%) were diagnosed with brain tumors. In 11\/11 (100%) patients with brain tumors, ULF-MRI identified tumor lesions corresponding to the findings of HF-MRI. In 7\/11 (63.6%) identification of all tumor lesions could be achieved. Three of four further relevant imaging findings in HF-MRI (e.g. acute hydrocephalus or concomitant ischemia) were also found in in ULF-MRI.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This single-center study demonstrates that ULF-MRI is a practical tool in neuro-oncology, which may particularly be helpful in resource-limited settings. Further research is required to define the role of ULF-MRI alongside existing imaging modalities for brain cancer diagnosis and management.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/nop\/npaf101","type":"journal-article","created":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T12:02:15Z","timestamp":1758801735000},"page":"415-421","source":"Crossref","is-referenced-by-count":1,"title":["Proof of concept: Portable ultra-low-field MRI for the assessment of brain tumors"],"prefix":"10.1093","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-2919-8622","authenticated-orcid":false,"given":"Thomas","family":"Zeyen","sequence":"first","affiliation":[{"name":"Department of Neurooncology, Center for Neurology, University Hospital Bonn , Bonn,","place":["Germany"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hemmen","family":"Sabir","sequence":"additional","affiliation":[{"name":"Department of Neonatology and Pediatric Intensive Care, 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Bonn,","place":["Germany"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nils","family":"Lehnen","sequence":"additional","affiliation":[{"name":"Department of Neuroradiology, University Hospital Bonn , Bonn,","place":["Germany"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mousa","family":"Zidan","sequence":"additional","affiliation":[{"name":"Department of Neuroradiology, University Hospital Bonn , Bonn,","place":["Germany"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simon","family":"Olbrich","sequence":"additional","affiliation":[{"name":"Department of Neuroradiology, University Hospital Bonn , Bonn,","place":["Germany"]},{"name":"Department of Epileptology, University Hospital Bonn , Bonn,","place":["Germany"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Annalena","family":"Lange","sequence":"additional","affiliation":[{"name":"Department of Neuroradiology, University Hospital Bonn , 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Bonn,","place":["Germany"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jennifer","family":"Faber","sequence":"additional","affiliation":[{"name":"German Center for Neurodegenerative Diseases (DZNE) , Bonn,","place":["Germany"]},{"name":"Department of Movement Disorders, University of Bonn , Bonn,","place":["Germany"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lea","family":"R\u00f6ver","sequence":"additional","affiliation":[{"name":"Department of Neurooncology, Center for Neurology, University Hospital Bonn , Bonn,","place":["Germany"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Niklas","family":"Sch\u00e4fer","sequence":"additional","affiliation":[{"name":"Department of Neurooncology, Center for Neurology, University Hospital Bonn , 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