{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T01:41:08Z","timestamp":1789436468372,"version":"build-2803163510"},"reference-count":38,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2025,12,10]],"date-time":"2025-12-10T00:00:00Z","timestamp":1765324800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,6,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Malignant brain tumors inevitably recur, leading to progressive neurological decline. Palliative care is essential for optimizing patient outcomes, yet its integration into neuro-oncology remains inconsistent. We conducted a nationwide survey to evaluate palliative care practices among German neuro-oncologists and assessed the impact of physicians\u2019 comfort on end-of-life discussions in patient care.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A nationwide, anonymous survey was distributed to 481 neuro-oncologists who are members of the Neuro-oncology Working Group of the German Cancer Society. The questionnaire, developed in collaboration with board-certified palliative care specialists, evaluated physicians\u2019 demographic characteristics, palliative care knowledge, and access to palliative care resources.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Of 92 respondents (survey response rate: 92\/481 \u2013 19%), 81 (88%) reported comfort in discussing end-of-life issues, while 11 (12%) expressed discomfort. Physicians comfortable with these discussions more frequently addressed withholding of life-sustaining interventions (88% vs 55%), arranged home care (81% vs 64%), and facilitated hospice placement (68% vs 36%). They also initiated these conversations earlier and observed greater patient receptivity to palliative care.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>While most neuro-oncologists report comfort with end-of-life discussions, this comfort was associated with differences in timing and extent of palliative care integration. Our findings highlight the need for structured palliative care training to ensure timely and effective discussions, ultimately improving care for neuro-oncological patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/nop\/npaf123","type":"journal-article","created":{"date-parts":[[2025,12,8]],"date-time":"2025-12-08T12:36:51Z","timestamp":1765197411000},"page":"528-536","source":"Crossref","is-referenced-by-count":1,"title":["End-of-life challenges in neuro-oncological patient care: A survey from the Junge Neuroonkologische Arbeitsgemeinschaft"],"prefix":"10.1093","volume":"13","author":[{"given":"Lazaros","family":"Lazaridis","sequence":"first","affiliation":[{"name":"Department of Neurology, University Hospital Knappschaftskrankenhaus Bochum, Ruhr University Bochum , Bochum,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Niklas Benedikt","family":"Pepper","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, University Hospital M\u00fcnster , M\u00fcnster, Germany (N.B.P.)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paula","family":"Klein","sequence":"additional","affiliation":[{"name":"Department of Neurology, University Hospital Knappschaftskrankenhaus Bochum, Ruhr University Bochum , Bochum,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0683-0430","authenticated-orcid":false,"given":"Christoph","family":"Oster","sequence":"additional","affiliation":[{"name":"Department of Neurology and Center for Translational Neuro- and Behavioral Sciences (C-TNBS), Division of Clinical Neurooncology, University Medicine Essen, University Duisburg-Essen , Essen, Germany (C.O., S.Sh., C.K., M.G., S.K.)"},{"name":"German Cancer Consortium (DKTK), partner site Essen\/D\u00fcsseldorf, a partnership between DKFZ and University Hospital Essen , Germany (C.O., M.G., S.K.)"},{"name":"DKFZ-Division Translational Neurooncology at the West German Cancer Center (WTZ), University Medicine Essen, University Duisburg-Essen , Essen, Germany (C.O., M.G., S.K.)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarina","family":"Agkatsev","sequence":"additional","affiliation":[{"name":"Department of Neurology, University Hospital Knappschaftskrankenhaus Bochum, Ruhr University Bochum , Bochum,","place":["Germany"]},{"name":"Institute for Diversity Medicine, Ruhr University Bochum , Bochum, Germany (S.A.)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iris","family":"Mildenberger","sequence":"additional","affiliation":[{"name":"Department of Neurology, Medical Faculty Mannheim, Mannheim Center for Translational Neurosciences (MCTN), University of Heidelberg , Mannheim,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rebecca","family":"Berg","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Alfried Krupp Hospital , Essen,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sabine","family":"Seidel","sequence":"additional","affiliation":[{"name":"Department of Neurology, University Hospital Knappschaftskrankenhaus Bochum, Ruhr University Bochum , Bochum,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandeep","family":"Sharma","sequence":"additional","affiliation":[{"name":"Department of Neurology and Center for Translational Neuro- and Behavioral Sciences (C-TNBS), Division of Clinical Neurooncology, University Medicine Essen, University Duisburg-Essen , Essen, Germany (C.O., S.Sh., C.K., M.G., S.K.)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1114-2771","authenticated-orcid":false,"given":"Raphael","family":"Bodensohn","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, University Hospital T\u00fcbingen , T\u00fcbingen,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Hau","sequence":"additional","affiliation":[{"name":"Department of Neurology and Wilhelm Sander-NeuroOncology Unit, Unversity Hospital Regensburg , Regensburg,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ghazaleh","family":"Tabatabai","sequence":"additional","affiliation":[{"name":"Department of Neurology & Interdisciplinary Neuro-Oncology, University Hospital T\u00fcbingen, Hertie Institute for Clinical Brain Research, Center for Neuro-Oncology, Comprehensive Cancer Center, Eberhard-Karls-University T\u00fcbingen , T\u00fcbingen,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrik","family":"Roser","sequence":"additional","affiliation":[{"name":"Department of Adult Psychiatry and Psychotherapy, University Hospital of Psychiatry Zurich, University of Zurich , Zurich,","place":["Switzerland"]},{"name":"Department of Psychiatry and Psychotherapy, LVR-University Hospital Essen, University Duisburg-Essen , Essen,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernhard","family":"Mallmann","sequence":"additional","affiliation":[{"name":"Institute for Palliative Medicine, University Medicine Essen, University Duisburg-Essen , Essen,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1650-8875","authenticated-orcid":false,"given":"Christoph","family":"Kleinschnitz","sequence":"additional","affiliation":[{"name":"Department of Neurology and Center for Translational Neuro- and Behavioral Sciences (C-TNBS), Division of Clinical Neurooncology, University Medicine Essen, University Duisburg-Essen , Essen, Germany (C.O., S.Sh., C.K., M.G., S.K.)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9073-1821","authenticated-orcid":false,"given":"Ulrich","family":"Sure","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery and Spine Surgery, University Medicine Essen, University Duisburg-Essen , Essen,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Corinna","family":"Seliger","sequence":"additional","affiliation":[{"name":"Department of Neurology, University Hospital Knappschaftskrankenhaus Bochum, Ruhr University Bochum , Bochum,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Glas","sequence":"additional","affiliation":[{"name":"Department of Neurology and Center for Translational Neuro- and Behavioral Sciences (C-TNBS), Division of Clinical Neurooncology, University Medicine Essen, University Duisburg-Essen , Essen, Germany (C.O., S.Sh., C.K., M.G., S.K.)"},{"name":"German Cancer Consortium (DKTK), partner site Essen\/D\u00fcsseldorf, a partnership between DKFZ and University Hospital Essen , Germany (C.O., M.G., S.K.)"},{"name":"DKFZ-Division Translational Neurooncology at the West German Cancer Center (WTZ), University Medicine Essen, University Duisburg-Essen , Essen, Germany (C.O., M.G., S.K.)"},{"name":"Department of Neurology and Neurooncology, St. Marien Hospital L\u00fcnen , L\u00fcnen,","place":["Germany"]},{"name":"Department of Neurooncology, Center for Neurology, University Hospital Bonn , Bonn,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4746-887X","authenticated-orcid":false,"given":"Michael","family":"Platten","sequence":"additional","affiliation":[{"name":"Department of Neurology, Medical Faculty Mannheim, Mannheim Center for Translational Neurosciences (MCTN), University of Heidelberg , 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